Polymorphisms in Toll-like receptor genes influence antibody responses to cytomegalovirus glycoprotein B vaccineRavit Arav-Boger
Department of Pediatrics, Division of Infectious Diseases, Johns Hopkins Hospital, Baltimore, Maryland 21287 4933, USA
BMC Res Notes 5:140. 2012
..A clinical trial of CMV glycoprotein B (gB) vaccine in young women showed promising efficacy. Improved understanding of the basis for prevention of CMV infection is essential for developing improved vaccines...
- Seroprevalence of 13 common pathogens in a rapidly growing U.S. minority population: Mexican Americans from San Antonio, TX
Rohina Rubicz
Department of Genetics, Texas Biomedical Research Institute, PO Box 760549, San Antonio, TX 78245 0549, USA
BMC Res Notes 4:433. 2011
..abstract:..
- Establishing the baseline level of repetitive element expression in the human cortex
Svitlana Tyekucheva
Department of Biostatistics and Computational Biology, Dana Farber CancerInstitute, 450 Brookline Ave, Boston, 02115, USA
BMC Genomics 12:495. 2011
..Hence, we performed whole transcriptome sequencing to investigate the expression of repetitive elements in human frontal cortex using postmortem tissue obtained from the Stanley Medical Research Institute...
- A systematic evaluation of expression of HERV-W elements; influence of genomic context, viral structure and orientation
Fang Li
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
BMC Genomics 12:22. 2011
..Therefore, potential influences of genomic context, structure and orientation on the expression levels of individual HERV-W elements in normal human tissues were systematically investigated...
Serological evidence of exposure to Herpes Simplex Virus type 1 is associated with cognitive deficits in the CATIE schizophrenia sampleRobert H Yolken
Stanley Neurovirology Laboratory, Johns Hopkins School of Medicine, USA
Schizophr Res 128:61-5. 2011
..A better understanding of the role of HSV-1 may lead to better methods of treatment for the cognitive impairments associated with schizophrenia...
- Toxoplasma and schizophrenia
R H Yolken
Stanley Division of Developmental Neurovirology, Johns Hopkins University School of Medicine, Baltimore, MD 21287 4933, USA
Parasite Immunol 31:706-15. 2009
....
Antibodies to Toxoplasma gondii in individuals with first-episode schizophreniaR H Yolken
Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287 4933, USA
Clin Infect Dis 32:842-4. 2001
..We found that the individuals with first-episode schizophrenia had significantly increased levels of IgG, IgM, and IgA class antibodies to Toxoplasma proteins, as compared with the control subjects...
- Endogenous retroviruses and schizophrenia
R H Yolken
Johns Hopkins University School of Medicine, Stanley Division of Developmental Neurovirology, Department of Pediatrics, 600 N Wolfe Street, Blalock 1111, Baltimore, MD, USA
Brain Res Brain Res Rev 31:193-9. 2000
..The delineation of a role for retroviruses in disease pathogenesis might lead to new methods for the diagnosis and treatment of schizophrenia...
- Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder. The Stanley Neuropathology Consortium
N L Johnston-Wilson
Stanley Division of Developmental Neurovirology, Johns Hopkins University, Baltimore, MD 21287 4933, USA
Mol Psychiatry 5:142-9. 2000
..Two spots, carbonic anhydrase 1 and fructose biphosphate aldolase C, show increase in one or more diseases compared to controls. Proteomic analysis may identify novel pathogenic mechanisms of human neuropsychiatric diseases...
- Emerging technologies for large-scale screening of human tissues and fluids in the study of severe psychiatric disease
N L Johnston-Wilson
Stanley Division of Devlopmental Neurovirology, John Hopkins School of Medicine, Baltimore, MD 21287, USA
Int J Neuropsychopharmacol 4:83-92. 2001
..The characterization of these pathways may allow for the development of new methods for the diagnosis and treatment of schizophrenia, bipolar disorder, and other human psychiatric diseases...
- Serial analysis of gene expression in the frontal cortex of patients with bipolar disorder
Y Sun
Stanley Division of Developmental Neurovirology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Br J Psychiatry Suppl 41:s137-41. 2001
..CONCLUSION: The SAGE technique offers promise for the characterisation of complex human brain diseases...
- Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia
H Karlsson
Stanley Division of Developmental Neurovirology, Department of Pediatrics, and Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
Proc Natl Acad Sci U S A 98:4634-9. 2001
..The further characterization of retroviral elements within the central nervous system of individuals with schizophrenia might lead to improved methods for the diagnosis and management of this disorder...
- Are some cases of psychosis caused by microbial agents? A review of the evidence
R H Yolken
The Stanley Laboratory of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University Medical Center, Baltimore, MD 21287 4933, USA
Mol Psychiatry 13:470-9. 2008
..The identification of infectious agents associated with the etiopathogenesis of schizophrenia might lead to new methods for the diagnosis, treatment and prevention of this disorder...
- Novel alpha7 nicotinic receptor isoforms and deficient cholinergic transcription in schizophrenia
E G Severance
Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD21287 4933, USA
Genes Brain Behav 7:37-45. 2008
..Our data demonstrate that alpha7 transcription is altered in several ways in SZ, suggesting that transcription-level mechanisms could account in part for the impaired cholinergic neurotransmission observed in this disease...
- Lack of RIC-3 congruence with beta2 subunit-containing nicotinic acetylcholine receptors in bipolar disorder
E G Severance
Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
Neuroscience 148:454-60. 2007
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