Li Y, Chen Z, Liu Z, Liu J, Yang J, Li Q, et al
. First report of Theileria and Anaplasma in the Mongolian gazelle, Procapra gutturosa. Parasit Vectors. 2014;7:614 pubmed publisher
..gutturosa in China. Our results extend our understanding of the epidemiology of theileriosis and anaplasmosis in P. gutturosa, and will facilitate the implementation of measures to control these tick-borne diseases in China. ..
Wang J, Yang J, Liu J, Wang X, Xu J, Liu A, et al
. Molecular detection and genetic diversity of Theileria orientalis in cattle in China. Parasitol Res. 2018;117:3689-3694 pubmed publisher
..orientalis comprised of eight MPSP types, 1, 2, 3, 4, 5, 7, N1, and N2. This is the first report of new T. orientalis MPSP genotypes N1 and N2 in cattle in China. ..
Yang J, Li Y, Liu Z, Liu J, Niu Q, Ren Q, et al
. Molecular detection and characterization of Anaplasma spp. in sheep and cattle from Xinjiang, northwest China. Parasit Vectors. 2015;8:108 pubmed publisher
..platys was identified in ruminants. This survey revealed a high prevalence of Anaplasma sp. infections in sheep and cattle in the northwestern border regions of China, indicating the potential risk of transboundary disease. ..
Lu Y, Wang Y, Li Y, Gou H, Luo J, Yin H, et al
. Identification and characterization of Tu88, an antigenic gene from Theileria uilenbergi. Exp Parasitol. 2015;153:63-7 pubmed publisher
..These findings suggest that Tu88 is a potential candidate antigen for the development of a sero-diagnostic tool. ..
Tian Z, Du X, Du J, Gao S, Yu R, Hassan M, et al
. Development of an indirect ELISA based on the recombinant Spm2 protein for detection of tropical theileriosis. Acta Trop. 2018;182:232-236 pubmed publisher
..This indicated that the Spm2 ELISA could be used as a reliable diagnostic tool for serological survey of T. annulata infection in areas where Theileria parva is not present. ..
Yang J, Liu Z, Niu Q, Tian Z, Liu J, Guan G, et al
. Tick-borne zoonotic pathogens in birds in Guangxi, Southwest China. Parasit Vectors. 2015;8:637 pubmed publisher
..were identified in wild birds in southwest China. The presence of these agents in birds increases the potential spread over long distances and the risk of transmission of infection from birds to new hosts, including humans. ..
Niu Q, Liu Z, Yang J, Yu P, Pan Y, Zhai B, et al
. Genetic diversity and molecular characterization of Babesia motasi-like in small ruminants and ixodid ticks from China. Infect Genet Evol. 2016;41:8-15 pubmed publisher
..B. motasi-like infections have not previously been reported in D. silvarum, I. persulcatus or R. sanguineus. The findings obtained in this study could be used for planning effective control strategies against babesiosis in China. ..
Niu Q, Liu Z, Yang J, Yu P, Pan Y, Zhai B, et al
. Expression analysis and biological characterization of Babesia sp. BQ1 (Lintan) (Babesia motasi-like) rhoptry-associated protein 1 and its potential use in serodiagnosis via ELISA. Parasit Vectors. 2016;9:313 pubmed publisher
..The results indicated that the average positive rate was 36.02 %. The present study suggests that rRAP-1a61-1/CT might be a potential diagnostic antigen for detecting several isolates of B. motasi-like parasites infection. ..
Xing S, Du J, Gao S, Tian Z, Zheng Y, Liu G, et al
. Analysis of the miRNA expression profile in an Aedes albopictus cell line in response to bluetongue virus infection. Infect Genet Evol. 2016;39:74-84 pubmed publisher
..albopictus cells. This investigation provides information concerning the cellular miRNA expression profile in response to BTV infection, and it offers clues for identifying potential candidates for vector-based antiviral strategies. ..
Lu Y, Guan G, Jiang T, Li Y, Yang J, Liu G, et al
. Development of an immunochromatographic strip for the serodiagnosis of Theileria infection in sheep. Parasit Vectors. 2015;8:621 pubmed publisher
..This is a rapid test (approximately 15Â min to completion) for the detection of T. uilenbergi and/or T. luwenshuni infection that is easy to perform and; delivers results that are visible to the naked eye. ..
Tian Z, Du J, Yang J, Liu A, Liu X, Liu G, et al
. A PCR-RFLP Assay targeting RPS8 gene for the discrimination between bovine Babesia and Theileria species in China. Parasit Vectors. 2015;8:475 pubmed publisher
Tian Z, Du J, Gao S, Yang J, Luo J, Xing S, et al
. Primary characterization of a putative novel TBC1 domain family member 13 from Haemaphysalis qinghaiensis. Vet Parasitol. 2016;223:14-9 pubmed publisher
..8% oviposition compared to the control group. These results indicated that the HqTBC1D13 in ticks could be invovled in the regulation of feeding and oviposition. ..
Qin G, Li Y, Liu J, Liu Z, Yang J, Zhang L, et al
. Molecular detection and characterization of Theileria infection in cattle and yaks from Tibet Plateau Region, China. Parasitol Res. 2016;115:2647-52 pubmed publisher
..No other Theileria sp. was detected in these samples. T. sinensis and T. orientalis infections were detected in cattle and yaks, and T. luwenshuni was discovered for the first time in cattle and yaks in the Tibet Plateau Region, China. ..
Gao S, Du J, Tian Z, Xing S, Chang H, Liu G, et al
. Genome analysis of an atypical bovine pestivirus from fetal bovine serum. Virus Genes. 2016;52:561-3 pubmed publisher
..Alignment of the complete nucleotide sequence and phylogenetic analysis indicate that this viral isolate belongs to atypical pestiviruses. ..
Yang J, Tian Z, Liu Z, Niu Q, Han R, Li Y, et al
. Novel spotted fever group rickettsiae in Haemaphysalis qinghaiensis ticks from Gansu, Northwest China. Parasit Vectors. 2016;9:146 pubmed publisher
Niu Q, Liu Z, Yu P, Yang J, Abdallah M, Guan G, et al
. Genetic characterization and molecular survey of Babesia bovis, Babesia bigemina and Babesia ovata in cattle, dairy cattle and yaks in China. Parasit Vectors. 2015;8:518 pubmed publisher
..The data obtained in this study can be used to plan effective control strategies against babesiosis in China. ..
Yu P, Niu Q, Liu Z, Yang J, Chen Z, Guan G, et al
. Molecular epidemiological surveillance to assess emergence and re-emergence of tick-borne infections in tick samples from China evaluated by nested PCRs. Acta Trop. 2016;158:181-188 pubmed publisher
..qinghaiensis, and I. persulcatus and Ehrlichia canis (named E. canis-like) from Haemaphysalis bispinosa were also detected in this work. ..
Yang J, Liu Z, Niu Q, Liu J, Xie J, Chen Q, et al
. Evaluation of different nested PCRs for detection of Anaplasma phagocytophilum in ruminants and ticks. BMC Vet Res. 2016;12:35 pubmed publisher
..Two A. phagocytophilum genotypes were identified, that varied between sheep and cattle in sample collection sites. This report provides more valuable information for the diagnosis and management of granulocytic anaplasmosis in China. ..
Omar Abdallah M, Niu Q, Yu P, Guan G, Yang J, Chen Z, et al
. Identification of piroplasm infection in questing ticks by RLB: a broad range extension of tick-borne piroplasm in China?. Parasitol Res. 2016;115:2035-44 pubmed publisher
..The piroplasms species-specific RLB assay may have potential clinical application in the simultaneous detection and differentiation of Babesia and Theileria species. ..
Yang J, Han R, Liu Z, Niu Q, Guan G, Liu G, et al
. Insight into the genetic diversity of Anaplasma marginale in cattle from ten provinces of China. Parasit Vectors. 2017;10:565 pubmed publisher
..Forty-two Msp1a tandem repeats and 61 genotypes of A. marginale were identified. This study, for the first time, revealed the genetic diversity of A. marginale strains in cattle in China. ..
Han R, Yang J, Niu Q, Liu Z, Chen Z, Kan W, et al
. Molecular prevalence of spotted fever group rickettsiae in ticks from Qinghai Province, northwestern China. Infect Genet Evol. 2018;57:1-7 pubmed publisher
..nuttalli and I. crenulatus. These findings extend our knowledge of the potential vector spectrum and distribution of rickettsiae, and provided valuable information for assessing the potential risk for public health. ..
Zhao S, Guan G, Liu J, Liu A, Li Y, Yin H, et al
. Screening and identification of host proteins interacting with Theileria annulata cysteine proteinase (TaCP) by yeast-two-hybrid system. Parasit Vectors. 2017;10:536 pubmed publisher
..The interaction with CRBN and Ppp4C indicate that TaCP possibly is involved in regulating signaling pathways and cell proliferation, which is helpful for understanding the interaction between T. annulata and host cells. ..
Ali A, Salih D, Njahira M, Hassan S, El Hussein A, Liu Z, et al
. Genotyping of Theileria lestoquardi from sheep and goats in Sudan to support control of Malignant Ovine Theileriosis. Vet Parasitol. 2017;239:7-14 pubmed publisher
..lestoquardi. The results of this work will inform on the best approach for controlling MOT in Sudan. ..
Li S, Liu J, Liu A, Li Y, Wang S, Wang S, et al
. Molecular investigation of piroplasma infection in white yaks (Bos grunniens) in Gansu province, China. Acta Trop. 2017;171:220-225 pubmed publisher
..annulata, T. sergenti and T. sinensis. The findings also offer novel insights into the role of white yaks in Babesia/Theileria epidemiology and valuable information for the control and management of piroplasmosis in white yaks. ..
Li Y, Zhang X, Liu Z, Chen Z, Yang J, He H, et al
. An epidemiological survey of Theileria infections in small ruminants in central China. Vet Parasitol. 2014;200:198-202 pubmed publisher
Chen X, Yang J, Ji Y, Okoth E, Liu B, Li X, et al
. Recombinant Newcastle disease virus expressing African swine fever virus protein 72 is safe and immunogenic in mice. Virol Sin. 2016;31:150-9 pubmed publisher
..Immunization also elicited T-cell proliferation and secretion of IFN-Î³ and IL-4. Taken together, these results indicate that rNDV expressing ASFV p72 might be a potential vaccine candidate for preventing ASF. ..
Guan G, Korhonen P, Young N, Koehler A, Wang T, Li Y, et al
. Genomic resources for a unique, low-virulence Babesia taxon from China. Parasit Vectors. 2016;9:564 pubmed
..Moreover, the present genomic resource and an in vitro culture system for Bx raises the prospect of establishing a functional genomic platform to explore essential genes as new intervention targets against babesiosis. ..
Wang T, Guan G, Korhonen P, Koehler A, Young N, Hall R, et al
. Mitochondrial genomes of two Babesia taxa from sheep in China as a foundation for population genetic and epidemiological investigations. Infect Genet Evol. 2017;47:51-55 pubmed publisher
..We propose that the sequencing-bioinformatic approach used here should be applicable to a wide range of protists of veterinary importance. ..
Niu Q, Liu Z, Yang J, Gao S, Pan Y, Guan G, et al
. Genetic characterization and molecular survey of Babesia sp. Xinjiang infection in small ruminants and ixodid ticks in China. Infect Genet Evol. 2017;49:330-335 pubmed publisher
..Xinjiang from field blood and tick samples indicated 100% identity. The presence of Babesia sp. Xinjiang infection may increase in China. Novel potential transmitting vectors might be more extensive than previously thought. ..
Yan D, Teng Z, Sun S, Jiang S, Dong H, Gao Y, et al
. Foot-and-mouth disease virus-like particles as integrin-based drug delivery system achieve targeting anti-tumor efficacy. Nanomedicine. 2017;13:1061-1070 pubmed publisher
..All results supported the potential of FMDV VLPs as a platform for specific targeted delivery of drugs or chemical reagents. ..
Wang T, Guan G, Korhonen P, Koehler A, Hall R, Young N, et al
. The apicoplast genomes of two taxonomic units of Babesia from sheep. Vet Parasitol. 2017;233:123-128 pubmed publisher
..Although the focus of the present study was on Babesia, we propose that the present sequencing-bioinformatic approach should be applicable to organellar genomes of a wide range of apicomplexans of veterinary importance. ..
Yang J, Liu Z, Niu Q, Liu J, Han R, Liu G, et al
. Molecular survey and characterization of a novel Anaplasma species closely related to Anaplasma capra in ticks, northwestern China. Parasit Vectors. 2016;9:603 pubmed
..capra-like bacteria. The present study reports a potential novel Anaplasma species closely related to A. capra in H. qinghaiensis in northwestern China. The zoonotic potential of A. capra-like bacteria needs to be further determined. ..
Yang J, Liu Z, Niu Q, Liu J, Han R, Guan G, et al
. Anaplasma phagocytophilum in sheep and goats in central and southeastern China. Parasit Vectors. 2016;9:593 pubmed
..Moreover, a potential novel Anaplasma species was reported in goats. Our findings provide additional information on the complexity of A. phagocytophilum in terms of genetic diversity in China. ..
Zheng F, Chen Q, Li Z, Gong X, Wang J, Yin H. Experimental infection with bovine ephemeral fever virus and analysis of its antibody response cattle. Res Vet Sci. 2016;104:146-51 pubmed publisher
..However, after 3 or 6months, when nAbs were no longer apparent, re-infected cattle displayed typical symptoms of BEF. Our findings indicated that vaccination should be performed once the titer of nAb decreased to 5 or 6. ..
Yin F, Liu J, Liu A, Li Y, Luo J, Guan G, et al
. Rapid diagnosis of Theileria annulata by recombinase polymerase amplification combined with a lateral flow strip (LF-RPA) in epidemic regions. Vet Parasitol. 2017;237:125-129 pubmed publisher
..annulata in endemic regions with limited to fewer and local resources and could also be a potential technique for the surveillance and control of blood protozoa. ..
Zhai B, Niu Q, Yang J, Liu Z, Liu J, Yin H, et al
. Identification and molecular survey of Borrelia burgdorferi sensu lato in sika deer (Cervus nippon) from Jilin Province, north-eastern China. Acta Trop. 2017;166:54-57 pubmed publisher
..This is the first report of Borrelia pathogens in sika deer in China. The findings in this study indicated that sika deer as potential natural host and may spread Lyme disease pathogen to animals, ticks, and even humans. ..
Li Y, Liu Z, Liu J, Yang J, Li Q, Guo P, et al
. Seroprevalence of bovine theileriosis in northern China. Parasit Vectors. 2016;9:591 pubmed
..This is the first report on the seroprevalence of bovine theileriosis in northern China, and it also provides seroepidemiological data on bovine theileriosis in China. ..
Yang J, Han R, Niu Q, Liu Z, Guan G, Liu G, et al
. Occurrence of four Anaplasma species with veterinary and public health significance in sheep, northwestern China. Ticks Tick Borne Dis. 2018;9:82-85 pubmed publisher
..This study gives the first insight of presence of four distinct Anaplasma species with veterinary and medical significance in sheep in northwestern China. ..
Yu P, Liu Z, Niu Q, Yang J, Abdallah M, Chen Z, et al
. Molecular evidence of tick-borne pathogens in Hyalomma anatolicum ticks infesting cattle in Xinjiang Uygur Autonomous Region, Northwestern China. Exp Appl Acarol. 2017;73:269-281 pubmed publisher
..Our findings highlight the risk of infection of animals and humans with these pathogens in north-western China. ..
Gao S, Du J, Tian Z, Niu Q, Zheng F, Huang D, et al
. Complete genome sequence of a bovine ephemeral fever virus JT02L strain in mainland China. Arch Virol. 2017;162:3555-3558 pubmed publisher
..To our knowledge, this is the first report describing the complete genome of a BEFV strain of East Asian lineage, which may facilitate studies on genomic diversity among geographic strains of BEFV in China and the world. ..
Yang J, Liu Z, Niu Q, Liu J, Han R, Guan G, et al
. A novel zoonotic Anaplasma species is prevalent in small ruminants: potential public health implications. Parasit Vectors. 2017;10:264 pubmed publisher
..7% in goats and sheep with isolates indistinguishable from those found in humans. These findings warrant increased public health awareness for human anaplasmosis. ..
Du J, Gao S, Tian Z, Xing S, Huang D, Zhang G, et al
. MicroRNA expression profiling of primary sheep testicular cells in response to bluetongue virus infection. Infect Genet Evol. 2017;49:256-267 pubmed publisher
..This study provides a valuable basis for further investigation on the roles of miRNAs in BTV replication and pathogenesis. ..