Genomes and Genes

Species

Fei Yin

Summary

Publications

  1. request reprint
    Wu L, Zhang C, Yin F. Dynamic changes in the proteomic profile of mesial temporal lobe epilepsy at different disease stages in an immature rat model. Protein Pept Lett. 2015;22:180-92 pubmed
    ..Our results show that the synaptic dysfunction caused by abnormal expression of synaptic proteins play a critical role in the pathogenesis of chronic MTLE. ..
  2. request reprint
    Ma Y, Peng J, Wang Y, Chen Y, Wu L, Yin F. [Clinical features and genome-wide copy number variation analysis in 60 children with early-onset epileptic encephalopathies of unknown cause]. Zhongguo Dang Dai Er Ke Za Zhi. 2014;16:1100-4 pubmed
    ..This research expands the gene bank of EEEs and improves the understanding about possible etiology of unexplained EEEs. The results provide a reference for genetic counseling regarding reproduction in the patient's family. ..
  3. Xiao Z, Peng J, Yang L, Kong H, Yin F. Interleukin-1β plays a role in the pathogenesis of mesial temporal lobe epilepsy through the PI3K/Akt/mTOR signaling pathway in hippocampal neurons. J Neuroimmunol. 2015;282:110-7 pubmed publisher
    ..Therefore, modulation of the PI3K/Akt/mTOR signaling pathway may be a novel therapeutic target for the treatment of MTLE. ..
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    He F, Peng J, Yin F. [Progress in diagnosis and treatment of intracranial hypertension and hydrocephalus in children with intracranial infections]. Zhongguo Dang Dai Er Ke Za Zhi. 2015;17:549-53 pubmed
    ..This paper introduces the progress in the etiology, diagnosis, and treatment of intracranial hypertension and hydrocephalus in children with intracranial infections. ..
  5. Wang Y, Yin F. A Review of X-linked Charcot-Marie-Tooth Disease. J Child Neurol. 2016;31:761-72 pubmed publisher
    ..Moreover, several cases are presented to illustrate the central nervous system manifestations. ..
  6. Kessi M, Peng J, Yang L, Xiong J, Duan H, Pang N, et al. Genetic etiologies of the electrical status epilepticus during slow wave sleep: systematic review. BMC Genet. 2018;19:40 pubmed publisher
    ..We also suggest development of common cut-off value for spike-wave index to ensure common language among clinicians and researchers. ..
  7. Ma Y, Wang Y, He F, Chen C, Zhang C, Deng X, et al. Analysis copy number variation of Chinese children in early-onset epileptic encephalopathies with unknown cause. Clin Genet. 2016;90:428-436 pubmed publisher
    ..Further, we identified potential candidate gene involved in EOEEs. The association of CNVs and clinical features will contribute to the understanding of EOEEs. ..
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    Xiong J, Peng J, Duan H, Chen C, Wang X, Chen S, et al. [Recurrent convulsion and pulmonary infection complicated by psychomotor retardation in an infant]. Zhongguo Dang Dai Er Ke Za Zhi. 2018;20:154-157 pubmed
    ..For children with unexplained early infantile epileptic encephalopathy, GNAO1 gene mutations should be considered and genetic tests should be performed as early as possible. Recurrent pulmonary infection should also be taken seriously. ..
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    Yang L, Kong H, Zhang X, Yin F. [Roles of PKCα on the biological functions of T cells]. Zhongguo Dang Dai Er Ke Za Zhi. 2015;17:1354-9 pubmed
    ..The differentiation rate of Th17 cells decreased, while the iTreg production increased in the PKCα⁻/⁻ group compared with the PKCα⁺/⁺ group. PKC-α is proinflammatory. ..

More Information

Publications11

  1. Yang L, Qiao G, Hassan Y, Li Z, Zhang X, Kong H, et al. Program Death-1 Suppresses Autoimmune Arthritis by Inhibiting Th17 Response. Arch Immunol Ther Exp (Warsz). 2016;64:417-23 pubmed publisher
    ..Therefore, our data indicate that PD-1 dampens antigen-specific Th17 response, thus inhibiting the disease. ..
  2. Wang Y, Zhang W, Yin J, Lu Q, Yin F, He F, et al. Anti-N-methyl-d-aspartate receptor encephalitis in children of Central South China: Clinical features, treatment, influencing factors, and outcomes. J Neuroimmunol. 2017;312:59-65 pubmed publisher
    ..Children with anti-NMDAR encephalitis in China have a much lower incidence of tumors, lower mortality rates, and a lower proportion of lethal autonomic instability than adults. ..