The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degenerationZuhal Yildirim
Etimesgut Public Health Laboratory, Ankara, Turkey
Clinics (Sao Paulo) 66:743-6. 2011
..To investigate the role of oxidant/antioxidant status and protein oxidation in the development of age-related macular degeneration...
Pseudoexfoliation syndrome and trace elementsZuhal Yildirim
Gazi University, Faculty of Medicine, Department of Medical Biochemistry, 06510 Besevler, Ankara, Turkey
Ann N Y Acad Sci 1100:207-12. 2007
..38-92.14 microg/g tissue) was not statistically different. The decreased content of zinc could increase oxidative stress. The results support the role of oxidative stress in the development of PSX in cataract patients...
Effects of taurine in cellular responses to oxidative stress in young and middle-aged rat liverZuhal Yildirim
Gazi University, Faculty of Medicine, Department of Medical Biochemistry, 06510 Besevler, Ankara, Turkey
Ann N Y Acad Sci 1100:553-61. 2007
..These results suggested that exogenous taurine might play a role in aging by means of its reducing effects on free radical levels in parallel to an increase in the antioxidant capacity...
The evaluation of the oxidative stress parameters in nondiabetic and diabetic senile cataract patientsZuhal Yildirim
Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Besevler, Ankara, Turkey
Biol Trace Elem Res 128:135-43. 2009
..Oxidative events are of great importance in diabetic complications and, particularly in the lens, may have a role in the pathogenesis of cataract associated with diabetes mellitus as exhibited in this study...
Fluorometric determination of acid proteinase activity in Candida albicans strains from diabetic patients with vulvovaginal candidiasisZuhal Yildirim
Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Besevler, Ankara, Turkey
Mycoses 54:e463-7. 2011
..Improving glucose control may reduce the risk of Candida colonisation and potentially symptomatic infection, among women with diabetes and hence may be useful even for weaker enzyme activity measurements...
Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbitsAydemir Kale
Department of Neurosurgery, Gazi University, Faculty of Medicine, Ankara, Turkey
J Neurosurg Spine 15:228-37. 2011
..This study aims to investigate the neuroprotective effects of gabapentin in an experimental spinal cord ischemia reperfusion injury...
Antioxidant enzymes and diabetic retinopathyZuhal Yildirim
Department of Medical Biochemistry, Faculty of Medicine, Gazi University, 06510 Besevler, Ankara, Turkey
Ann N Y Acad Sci 1100:199-206. 2007
..AOPP levels were statistically increased in group 1 compared to control group. It can be suggested that hyperglycemia in DM is associated with accelerated nonenzymatic glycation and oxidative stress...
Anti-apoptotic and neuroprotective effects of α-lipoic acid on spinal cord ischemia-reperfusion injury in rabbitsHakan Emmez
Department of Neurosurgery, Faculty of Medicine, Gazi University, Polikliniği Kat 1, Ankara 06500, Turkey
Acta Neurochir (Wien) 152:1591-600; discussion 1600-1. 2010
..The aim of this study is to investigate the neuroprotective and anti-apoptotic effects of alpha-lipoic acid on spinal cord ischemia-reperfusion...
The importance of serum lipids in exudative diabetic macular edema in type 2 diabetic patientsNil Irem Uçgun
Gazi University, Faculty of Medicine, Department of Medical Biochemistry, 06510 Besevler, Ankara, Turkey
Ann N Y Acad Sci 1100:213-7. 2007
..We must consider regulation of high blood sugar and elevated total serum cholesterol or LDL levels in patients with macular edema and high hard exudates...
Neuroprotective effects of infliximab in experimental spinal cord ischemic injuryCagatay Guven
Department of Neurosurgery, Gazi University, Faculty of Medicine, Besevler, Ankara 06500, Turkey
J Clin Neurosci 17:1563-7. 2010
..These results indicate that infliximab may protect the spinal cord against injury in a rabbit I/R model...