Clinical significance of detecting survivin-expressing circulating cancer cells in patients with non-small cell lung cancerShang mian Yie
Core Laboratory, Sichuan Academy of Medical Sciences, Sichuan Provincial People s Hospital, Chengdu, Sichuan, PR China
Lung Cancer 63:284-90. 2009
..5; 95% CI=2.67-70.9; P=0.008) and survival (HR=1.35; 95% CI=1.02-4.31; P=0.049). Thus, detection of survivin-expressing CCC could be used in the prediction of disease recurrence as well as in the prognosis of NSCLC...
Expression of human leucocyte antigen G (HLA-G) is associated with prognosis in non-small cell lung cancerShang mian Yie
Chengdu Bioengineering Institute for Cancer Research, Chengdu, Sichuan, PR China
Lung Cancer 58:267-74. 2007
..40-11.9). All in all, our results indicate that the expression of HLA-G is a characteristic feature of NSCLC, and they suggest that immunostaining by anti-HLA-G antibodies may be a potentially useful prognostic indicator...
- Expression of human leukocyte antigen G (HLA-G) correlates with poor prognosis in gastric carcinoma
Shang mian Yie
Chengdu Bioengineering Institute for Cancer Research, Chengdu, Sichuan, P R China
Ann Surg Oncol 14:2721-9. 2007
..Currently, we investigate whether or not HLA-G is also expressed in patients with gastric carcinoma and whether the expression has any clinical application value...
- Detection of Survivin-expressing circulating cancer cells in the peripheral blood of breast cancer patients by a RT-PCR ELISA
Shang mian Yie
Chengdu Bio Engineering Institute for Cancer Research, Chengdu, Sichuan, PR China
Clin Exp Metastasis 23:279-89. 2006
..Thus, the detection of circulating cancer cells expressing Survivin mRNA could provide valuable information for the prediction of metastasis and recurrence of breast cancer...
- Detection of survivin-expressing circulating cancer cells (CCCs) in peripheral blood of patients with gastric and colorectal cancer reveals high risks of relapse
Shang mian Yie
Core Laboratory, Sichuan Academy of Medical Sciences, Sichuan Provincial People s Hospital, 32 Yi Huan Lu Xi Er Duan 610078, Chengdu, Sichuan, People s Republic of China
Ann Surg Oncol 15:3073-82. 2008
..The objective of this study was to investigate whether or not the detection of survivin expression in the peripheral blood could also have significant effects on the clinical outcomes of patients with gastric and colorectal cancer...
- Human leukocyte antigen-G (HLA-G) as a marker for diagnosis, prognosis and tumor immune escape in human malignancies
Shang mian Yie
Research Center, The Second Medical College Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, PR China
Histol Histopathol 26:409-20. 2011
..In this review, we will summarize available literature data as well as our own works on HLA-G in cancer, and address some of the issues concerning its application in human neoplasia...
- HLA-G expression in human breast cancer: implications for diagnosis and prognosis, and effect on allocytotoxic lymphocyte response after hormone treatment in vitro
Xu He
Core Laboratory, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, People s Republic of China
Ann Surg Oncol 17:1459-69. 2010
..The aim of this study is to investigate clinical implications of human leukocyte antigen-G (HLA-G) expression in breast cancer...
- Human leukocyte antigen G expression: as a significant prognostic indicator for patients with colorectal cancer
Shang rong Ye
Department of Immunology, Chengdu Bioengineering Institute for Cancer Research, Chengdu, Sichuan, PR China
Mod Pathol 20:375-83. 2007
..021, relative risk 3.14; 95% confidence interval, 1.34-8.10). Therefore, it can be gathered that HLA-G might serve as an independent prognostic factor for colorectal cancer patients...
- Expression of HLA-G is associated with prognosis in esophageal squamous cell carcinoma
Shang mian Yie
Core Laboratory of Sichuan Academy of Medical Sciences, Chengdu, Sichuan, Peoples Republic of China
Am J Clin Pathol 128:1002-9. 2007
..Our results indicate that expression of HLA-G is a characteristic feature of ESCC and suggest that immunostaining by anti-HLA-G antibodies may be a potentially useful prognostic indicator...
- Detection of survivin-expressing circulating cancer cells in the peripheral blood of patients with esophageal squamous cell carcinoma and its clinical significance
Mei Cao
Core Laboratory, Sichuan Academy of Medical Sciences, Sichuan Provincial People s Hospital, Chengdu, Sichuan, People s Republic of China
Clin Exp Metastasis 26:751-8. 2009
..002 and 0.016, respectively). Examination of survivin-expressing CCC could provide valuable information in the prediction of haematogenous recurrence as well as in the prognosis of ESCC...
- Importance of HLA-G expression and tumor infiltrating lymphocytes in molecular subtypes of breast cancer
Dan Dan Dong
Department of Pathology, Sichuan Academy of Medical Sciences, Sichuan Provincial People s Hospital, Chengdu, Sichuan, PR China
Hum Immunol 73:998-1004. 2012
..Therefore, a combination of the status of HLA-G and TIL could improve the prognostic prediction for patients with various molecular subtypes of breast cancer...
- Human leukocyte antigen-G (HLA-G) expression in cervical lesions: association with cancer progression, HPV 16/18 infection, and host immune response
Dan Dan Dong
Department of Pathology, Sichuan Academy of Medical Sciences, Sichuan Provincial People s Hospital, Chengdu, Sichuan, PR China
Reprod Sci 17:718-23. 2010
..These results suggest that HLA-G expression in cervical lesions is associated with carcinogenesis, HPV infection, and host immune response...
- You Gui Wan can reverse atrophic effect of ovariectomy on rat vaginal fold and blood vessels in the lamina propria
Xiang Hu
Department of Gynecology and Obstetrics, The Second Medical College Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610041, P R China
Biol Pharm Bull 34:1808-14. 2011
..This indicates the herbal formula as an alternative to hormone replacement therapy in the management of menopausal vaginal atrophy. Recovery of ER expressions in the vagina might be one of mechanisms underlying the effects of YGW...
- Progesterone regulates HLA-G gene expression through a novel progesterone response element
Shang mian Yie
Department of Gynecology and Obstetrics, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
Hum Reprod 21:2538-44. 2006
..The objective of this study was to explore the molecular mechanisms of this effect...
- Progesterone enhances HLA-G gene expression in JEG-3 choriocarcinoma cells and human cytotrophoblasts in vitro
Shang-mian Yie
Department of Gynecology and Obstetrics, Sunnybrook and Women's College Health Science Center, Toronto, Ontario, Canada
Hum Reprod 21:46-51. 2006
..CONCLUSION: Progesterone has an up-regulatory effect on HLA-G gene expression in first trimester trophoblasts and JEG-3 cells in vitro...
- Low plasma HLA-G protein concentrations in early gestation indicate the development of preeclampsia later in pregnancy
Shang-mian Yie
Department of Obstetrics and Gynecology, Sunnybrook and Women's College Health Sciences Centre (SWCHSC, Toronto, Ontario, Canada
Am J Obstet Gynecol 193:204-8. 2005
..This suggests that determination of circulating HLA-G protein concentration may be useful as an early predictor for the development of PE...
- HLA-G protein concentrations in maternal serum and placental tissue are decreased in preeclampsia
Shang-mian Yie
Department of Obstetrics and Gynecology, Division of Reproductive Sciences, Toronto General Hospital Research Institute, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada
Am J Obstet Gynecol 191:525-9. 2004
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- Secretion of human leukocyte antigen-G by human embryos is associated with a higher in vitro fertilization pregnancy rate
Shang-mian Yie
Department of Obstetrics and Gynecology, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontartio, Canada
Fertil Steril 83:30-6. 2005
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