[Risk factors for metastasis and recurrence of hepatocellular carcinoma at different stages]Di Peng Ou
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha 410008, China
Zhong Nan Da Xue Xue Bao Yi Xue Ban 30:540-3. 2005
..To analyze the risk factors for metastasis and recurrence of hepatocellular carcinoma (HCC) postoperatively...
Correlation between CD105 expression and postoperative recurrence and metastasis of hepatocellular carcinomaLian Yue Yang
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, PR China
BMC Cancer 6:110. 2006
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- Role of AFP mRNA expression in peripheral blood as a predictor for postsurgical recurrence of hepatocellular carcinoma: a systematic review and meta-analysis
Xiang Ding
Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
World J Gastroenterol 11:2656-61. 2005
..To identify the role of alpha-fetoprotein (AFP) mRNA expression in peripheral blood one week after surgery as a predictor for recurrence of hepatocellular carcinoma (HCC)...
- Differentially expressed genes between solitary large hepatocellular carcinoma and nodular hepatocellular carcinoma
Lian Yue Yang
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Changsha 410008, Hunan Province, China
World J Gastroenterol 10:3569-73. 2004
..To study the difference in gene expression between solitary large hepatocellular carcinoma (SLHCC) and nodular hepatocellular carcinoma (NHCC)...
- Solitary large hepatocellular carcinoma: a specific subtype of hepatocellular carcinoma with good outcome after hepatic resection
Lian Yue Yang
Department of Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China
Ann Surg 249:118-23. 2009
..To evaluate and compare the clinical and pathologic characteristics and outcomes after hepatic resection of large hepatocellular carcinoma (SLHCC), small HCC (SHCC), and nodular HCC (NHCC)...
- Increased expression of Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 correlated with poor prognosis of hepatocellular carcinoma
Lian Yue Yang
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People s Republic of China
Clin Cancer Res 12:5673-9. 2006
..We thus examined the expression of WAVE2 in hepatocellular carcinoma (HCC) tissues to test whether the levels of WAVE2 expression correlated to the progression of HCC...
- Expression and significance of RhoC gene in hepatocellular carcinoma
Wei Wang
Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
World J Gastroenterol 9:1950-3. 2003
..To investigate the expression of RhoC gene in hepatocellular carcinoma (HCC) and to evaluate the relationship between RhoC gene expression and invasion and metastasis of HCC...
- Expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor in hepatocellular carcinoma: Impact on neovascularization and survival
Geng Wen Huang
Department of General Surgery and Liver Cancer Laboratory, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
World J Gastroenterol 11:1705-8. 2005
..To study the expression of hypoxia-inducible factor 1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in hepatocellular carcinoma (HCC) and the impact on neovascularization and survival...
- ADAM17 mRNA expression and pathological features of hepatocellular carcinoma
Xiang Ding
Liver Cancer Laboratory, Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
World J Gastroenterol 10:2735-9. 2004
..To study the expression of a disintegrin and metalloproteinase 17 (ADAM17) mRNA in hepatocellular carcinoma (HCC) and to evaluate the relationship between ADAM17 mRNA expression and clinicopathological features of HCC...
- Elevated expression of autocrine motility factor receptor correlates with overexpression of RhoC and indicates poor prognosis in hepatocellular carcinoma
Wei Wang
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, P R China
Dig Dis Sci 52:770-5. 2007
..Furthermore, our data indicated AMFR as a potential prognosis for HCC...
- Decreased expression of methyl methansulfonate and ultraviolet-sensitive gene clone 81 (Mus81) is correlated with a poor prognosis in patients with hepatocellular carcinoma
Fan Wu
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha City, PR China
Cancer 112:2002-10. 2008
..To investigate its role in human hepatocellular carcinoma (HCC), which currently is unknown, the authors examined the correlation between Mus81 expression and prognosis in patients with HCC...
- Expression of HIF-2alpha/EPAS1 in hepatocellular carcinoma
Gassimou Bangoura
Department of General Surgery and Liver Cancer Laboratory, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
World J Gastroenterol 10:525-30. 2004
..To investigate the expression of hypoxia-inducible factor (HIF)-2alpha/endothelial PAS domain protein1 (EPAS1) in hepatocellular carcinoma (HCC)...
- p53-induced RING-H2 protein, a novel marker for poor survival in hepatocellular carcinoma after hepatic resection
Xiao Min Wang
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha City, People s Republic of China
Cancer 115:4554-63. 2009
..The objective of this retrospective study was to investigate the expression of PIRH2 and its relation to prognosis in patients with HCC after hepatic resection...
- Expressions of cysteine-rich61, connective tissue growth factor and Nov genes in hepatocellular carcinoma and their clinical significance
Zhi Jun Zeng
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
World J Gastroenterol 10:3414-8. 2004
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- [Down-regulated expression of UNC5b related to hepatocellular carcinoma angiogenesis]
Hua Zhang
Department of Surgery, Xiangya Hospital, Central South University, Changsha 410008, China
Zhonghua Wai Ke Za Zhi 47:1569-73. 2009
..To investigate the relationship between UNC5b gene expression and angiogenesis of hepatocellular carcinoma (HCC)...
- Effects of PI3K and p42/p44 MAPK on overexpression of vascular endothelial growth factor in hepatocellular carcinoma
Geng Wen Huang
Department of Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
World J Gastroenterol 10:809-12. 2004
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- The hepatitis B virus X protein promotes hepatocellular carcinoma metastasis by upregulation of matrix metalloproteinases
Di Peng Ou
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China
Int J Cancer 120:1208-14. 2007
..Together, our results support a model in which HBx contributes to HCC metastasis by upregulation of MMPs...
- Novel role for epidermal growth factor-like domain 7 in metastasis of human hepatocellular carcinoma
Fan Wu
Liver Cancer Laboratory, Xiangya Hospital, Central South University, Changsha, Hunan, China
Hepatology 50:1839-50. 2009
..CONCLUSION: Our study suggests Egfl7 as a novel prognostic marker for metastasis of HCC and a potential therapeutic target...
- Identification of gene expression profiling in hepatocellular carcinoma using cDNA microarrays
Wei Wang
Liver Cancer Laboratory, Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, People s Republic of China
Dig Dis Sci 54:2729-35. 2009
..This study describes a gene expression profiling of HCC, which provides an extensive list of potential molecular markers for early diagnosis and molecular targets for the development of drugs to treat patients with primary HCC...
- Decreased expression of inhibitor of growth 4 correlated with poor prognosis of hepatocellular carcinoma
Feng Fang
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha City, Hunan Province, PR China
Cancer Epidemiol Biomarkers Prev 18:409-16. 2009
..Here, we examined the expression of ING4 in hepatocellular carcinoma (HCC) tissues and analyzed its correlation with the progression of HCC...
- [Increased expression of Abi1 in hepatocellular carcinoma and its correlation with poor prognosis of hepatocellular carcinoma]
Si Yu Liu
Department of Surgery, Xiangya Hospital, Central South University, Changsha 410008, China
Zhonghua Wai Ke Za Zhi 47:1732-5. 2009
..To investigate the expression of Abi1 in hepatocellular carcinoma (HCC) and the correlation between its expression level and clinical pathological characteristics as well as prognosis of HCC...
- Metallothionein expression in hepatocellular carcinoma
Geng Wen Huang
Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
World J Gastroenterol 8:650-3. 2002
..To investigate the expression of metallothioneins (MTs), which were recently thought to have close relationship with tumors, in human hepatocellular carcinoma...
Novel roles of Vmp1: Inhibition metastasis and proliferation of hepatocellular carcinomaLei Guo
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha, China
Cancer Sci 103:2110-9. 2012
..Therefore, our data suggest Vmp1 is a novel prognostic marker and potential therapeutic target for metastasis of HCC...
- [Overexpression of the RhoC gene correlates with invasion and metastasis of hepatocellular carcinoma]
Wei Wang
Liver Cancer Laboratory, Xiangya Hospital, Central South University, Changsha 410008, China
Zhonghua Zhong Liu Za Zhi 26:279-82. 2004
..05). Mutation of RhoC gene was found in none of the HCC specimens examined. CONCLUSION: Overexpression of RhoC gene may play an important role in carcinogenesis and progression of HCC...
- Determination of high mobility group A1 (HMGA1) expression in hepatocellular carcinoma: a potential prognostic marker
Zhi-Gang Chang
Liver Cancer Laboratory and Department of General Surgery, Xiangya Hospital, Central South University, Hunan, PR China
Dig Dis Sci 50:1764-70. 2005
..05). Our findings indicate that HMGA1 may be involved in the carcinogenesis and invasiveness of HCC and the determination of HMGA1 can be of great value in predicting the prognosis of patients with HCC...
- Clinical analysis of the risk factors for recurrence of HCC and its relationship with HBV
Di-Peng Ou
Liver Cancer Laboratory, Department of Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
World J Gastroenterol 11:2061-6. 2005
..HBV replication takes a great role in this process. From this study, we found that SLHCC has more satisfactory neoplasm biological behavior than NHCC...
- Caspase-8 in apoptosis of hepatoma cell induced by 5-fluorouracil
Tong-bo Yi
Department of General Surgery, Affiliated Hospital, Guilin Medical College, Guilin 541001, China
Hepatobiliary Pancreat Dis Int 2:98-101. 2003
..01). CONCLUSIONS: 5-Fu can induce apoptosis of HepG2 cells via caspase-8 signal transduction pathway, which can be blocked by IETD-FMK. 5-Fu promotes the increase of caspase-8 activity in a time- or concentration-dependent manner...
