Song Yang



  1. Liu T, Yang T, Gao M, Chen K, Yang S, Yu K, et al. The inhibitory mechanism of aurintricarboxylic acid targeting serine/threonine phosphatase Stp1 in Staphylococcus aureus: insights from molecular dynamics simulations. Acta Pharmacol Sin. 2019;: pubmed publisher
    ..This study indicated the inhibitory mechanism of ATA targeting Stp1 using MD simulations and sheds light on the future design of allosteric Stp1 inhibitors. ..
  2. Wang A, Li H, Zhang H, Pan H, Yang S. Efficient Catalytic Production of Biodiesel with Acid-Base Bifunctional Rod-Like Ca-B Oxides by the Sol-Gel Approach. Materials (Basel). 2018;12: pubmed publisher
    ..5%) at 65 °C after 2 h. The Ca-B(700) catalyst had good stability and reusability, which is a promising acid-base bifunctional catalytic material for the preparation of biodiesel. ..
  3. Zhou J, Tao Q, Wang P, Shao W, Wu Z, Li Z, et al. Antimicrobial evaluation and action mechanism of pyridinium-decorated 1,4-pentadien-3-one derivatives. Bioorg Med Chem Lett. 2018;28:1742-1746 pubmed publisher
    ..We anticipated that this finding can promote high-efficient lead compounds discovery in the research of antimicrobial chemotherapy. ..
  4. Yang S, Liu M, Zhao Q, Hu D, Xue W, Yang S. Synthesis and biological evaluation of betulonic acid derivatives as antitumor agents. Eur J Med Chem. 2015;96:58-65 pubmed publisher
    ..33% after 36 h of treatment at 10 μM. In addition, the study of cancer cell apoptotic signaling pathway indicated that the apoptosis of MGC-803 cells induced by compound 3k could be through the mitochondrial intrinsic pathway. ..
  5. Yang S, Liu M, Xiang H, Zhao Q, Xue W, Yang S. Synthesis and in vitro antitumor evaluation of betulin acid ester derivatives as novel apoptosis inducers. Eur J Med Chem. 2015;102:249-55 pubmed publisher
    ..Subsequent fluorescence staining and flow cytometric analysis indicated that compound 3c induced apoptosis in MGC-803 cell line, with an apoptosis ratio of 31.11% after 36 h of treatment at 10 μM 3c. ..
  6. Wang P, Zhou L, Zhou J, Wu Z, Xue W, Song B, et al. Synthesis and antibacterial activity of pyridinium-tailored 2,5-substituted-1,3,4-oxadiazole thioether/sulfoxide/sulfone derivatives. Bioorg Med Chem Lett. 2016;26:1214-7 pubmed publisher
    ..54 to 12.14 μg/mL. Our results demonstrate that pyridinium-tailored 1,3,4-oxadiazole thioether/sulfoxide/sulfone derivatives can serve as potential alternative bactericides for the management of plant bacterial diseases. ..
  7. Wang P, Gao M, Zhou L, Wu Z, Hu D, Hu J, et al. Synthesis and antibacterial activity of pyridinium-tailored aromatic amphiphiles. Bioorg Med Chem Lett. 2016;26:1136-9 pubmed publisher
    ..Our results suggest that pyridinium-tailored aromatic amphiphiles are promising bactericide candidates against plant bacterial diseases. ..
  8. Wu X, Liu B, Zhang Y, Jeret M, Wang H, Zheng P, et al. Enantioselective Nucleophilic ?-Carbon-Atom Amination of Enals: Carbene-Catalyzed Formal [3+2] Reactions. Angew Chem Int Ed Engl. 2016;55:12280-4 pubmed publisher
    ..The pyrazolidinone products from our catalytic reactions are common scaffolds in bioactive molecules, and can be easily transformed into useful compounds such as ?(3) -amino-acid derivatives. ..
  9. Wang P, Fang H, Shao W, Zhou J, Chen Z, Song B, et al. Synthesis and biological evaluation of pyridinium-functionalized carbazole derivatives as promising antibacterial agents. Bioorg Med Chem Lett. 2017;27:4294-4297 pubmed publisher
    ..This finding suggested that these compounds can serve as new lead compounds in research on antibacterial chemotherapy. ..