K Yamazaki

Summary

Publications

  1. pmc Problems in early diagnosis of bladder cancer in a spinal cord injury patient: report of a case of simultaneous production of granulocyte colony stimulating factor and parathyroid hormone-related protein by squamous cell carcinoma of urinary bladder
    Subramanian Vaidyanathan
    Regional Spinal Injuries Centre, District General Hospital, Southport PR8 6PN, UK
    BMC Urol 2:8. 2002
  2. ncbi request reprint Pulmonary lipomatous hemangiopericytoma: report of a rare tumor and comparison with solitary fibrous tumor
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    Ultrastruct Pathol 31:51-61. 2007
  3. ncbi request reprint A gastric carcinosarcoma with neuroendocrine cell differentiation and undifferentiated spindle-shaped sarcoma component possibly progressing from the conventional tubular adenocarcinoma; an immunohistochemical and ultrastructural study
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, 1 4 17 Mita, Minatoku, Tokyo 108 0073, Japan
    Virchows Arch 442:77-81. 2003
  4. ncbi request reprint Pulmonary well-differentiated fetal adenocarcinoma expressing lineage-specific transcription factors (TTF-1 and GATA-6) to respiratory epithelial differentiation: an immunohistochemical and ultrastructural study
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, 1 4 17 Mita, Minatoku, 108 0073, Tokyo, Japan
    Virchows Arch 442:393-9. 2003
  5. ncbi request reprint A case of splenic lymphoma with marked diffuse nodular fibrosis and calcification, complicated with severe autoimmune hemolytic anemia
    K Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    J Submicrosc Cytol Pathol 35:17-23. 2003
  6. ncbi request reprint An ultrastructural, immunohistochemical, and cytogenetical study of a monophasic pulmonary synovial sarcoma: implications of the frequent ultrastructure of oligocilia and concentric membranous bodies with positive immunostaining for VS38c and MEF2
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    Ultrastruct Pathol 27:235-41. 2003
  7. ncbi request reprint Systemic lupus erythematosus with hepatic aneurysm, valsalva sinus aneurysm and associated polyangiitis: aneurysmal wall remodeling with dense fibrosis and calcification mediated by residual smooth muscle cells
    K Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    Lupus 13:54-9. 2004
  8. ncbi request reprint Electron microscopy and immunohistochemistry studies of pulmonary carcinosarcomas expressing the transcription factor MEF-2 and showing significant cell-to-cell, cell-to-matrix, and epithelial-mesenchymal interactions
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, l 4 17 Mita, Minatoku, 108 0073 Tokyo, Japan
    Virchows Arch 444:542-53. 2004
  9. ncbi request reprint A unique pancreatic ductal adenocarcinoma with carcinosarcomatous histology, immunohistochemical distribution of hCG-beta, and the elevation of serum alpha-feto-protein
    K Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    J Submicrosc Cytol Pathol 35:343-9. 2003
  10. ncbi request reprint A seminal vesicle cyst complicated with a tumor like nodular mass of benign proliferating prostatic tissue: a case report with ultrastructural and immunohistochemical studies
    K Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    J Submicrosc Cytol Pathol 35:209-14. 2003

Collaborators

Detail Information

Publications62

  1. pmc Problems in early diagnosis of bladder cancer in a spinal cord injury patient: report of a case of simultaneous production of granulocyte colony stimulating factor and parathyroid hormone-related protein by squamous cell carcinoma of urinary bladder
    Subramanian Vaidyanathan
    Regional Spinal Injuries Centre, District General Hospital, Southport PR8 6PN, UK
    BMC Urol 2:8. 2002
    ..Typical symptoms and signs of a clinical condition may be absent in spinal cord injury (SCI) patients...
  2. ncbi request reprint Pulmonary lipomatous hemangiopericytoma: report of a rare tumor and comparison with solitary fibrous tumor
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    Ultrastruct Pathol 31:51-61. 2007
    ..These similarities and differences are discussed in the context of the currently favored diagnostic fusion of hemangiopericytoma and solitary fibrous tumor...
  3. ncbi request reprint A gastric carcinosarcoma with neuroendocrine cell differentiation and undifferentiated spindle-shaped sarcoma component possibly progressing from the conventional tubular adenocarcinoma; an immunohistochemical and ultrastructural study
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, 1 4 17 Mita, Minatoku, Tokyo 108 0073, Japan
    Virchows Arch 442:77-81. 2003
    ..It was speculated that the unique histology of carcinosarcoma might have progressed from the conventional type of pre-existing advanced tubular adenocarcinoma...
  4. ncbi request reprint Pulmonary well-differentiated fetal adenocarcinoma expressing lineage-specific transcription factors (TTF-1 and GATA-6) to respiratory epithelial differentiation: an immunohistochemical and ultrastructural study
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, 1 4 17 Mita, Minatoku, 108 0073, Tokyo, Japan
    Virchows Arch 442:393-9. 2003
    ..In the present case, tumor cells forming the peculiar histological, molecular, and ultrastructural constructions showed partial and incomplete mimicry of the morphogenesis of respiratory epithelium...
  5. ncbi request reprint A case of splenic lymphoma with marked diffuse nodular fibrosis and calcification, complicated with severe autoimmune hemolytic anemia
    K Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    J Submicrosc Cytol Pathol 35:17-23. 2003
    ....
  6. ncbi request reprint An ultrastructural, immunohistochemical, and cytogenetical study of a monophasic pulmonary synovial sarcoma: implications of the frequent ultrastructure of oligocilia and concentric membranous bodies with positive immunostaining for VS38c and MEF2
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    Ultrastruct Pathol 27:235-41. 2003
    ....
  7. ncbi request reprint Systemic lupus erythematosus with hepatic aneurysm, valsalva sinus aneurysm and associated polyangiitis: aneurysmal wall remodeling with dense fibrosis and calcification mediated by residual smooth muscle cells
    K Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    Lupus 13:54-9. 2004
    ..It was suspected that the generalized polyangiitis as a complication of SLE might have involved the intrahepatic arteries and Valsalva sinus wall and subsequently generated the aneurysm...
  8. ncbi request reprint Electron microscopy and immunohistochemistry studies of pulmonary carcinosarcomas expressing the transcription factor MEF-2 and showing significant cell-to-cell, cell-to-matrix, and epithelial-mesenchymal interactions
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, l 4 17 Mita, Minatoku, 108 0073 Tokyo, Japan
    Virchows Arch 444:542-53. 2004
    ....
  9. ncbi request reprint A unique pancreatic ductal adenocarcinoma with carcinosarcomatous histology, immunohistochemical distribution of hCG-beta, and the elevation of serum alpha-feto-protein
    K Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    J Submicrosc Cytol Pathol 35:343-9. 2003
    ....
  10. ncbi request reprint A seminal vesicle cyst complicated with a tumor like nodular mass of benign proliferating prostatic tissue: a case report with ultrastructural and immunohistochemical studies
    K Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    J Submicrosc Cytol Pathol 35:209-14. 2003
    ..It is extremely important to differentiate between a benign proliferation and a malignant one, when the nodular mass is found in the seminal vesicle cyst...
  11. ncbi request reprint Type-II pneumocyte differentiation in pulmonary sclerosing hemangioma: ultrastructural differentiation and immunohistochemical distribution of lineage-specific transcription factors (TTF-1, HNF-3 alpha, and HNF-3 beta) and surfactant proteins
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, l 4 17 Mita, Minatoku, 108 0073, Tokyo, Japan
    Virchows Arch 445:45-53. 2004
    ..PSH is a proliferation of rather fetal type-II pneumonocytes (pneumocytoma or pneumoblastoma?)...
  12. ncbi request reprint CD10- and CD34-positive periglandular stromal cells in pulmonary benign metastasizing leiomyoma with metaplastic adenomyomatous glands: an ultrastructural and immunohistochemical study
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, l 4 17 Mita, Minatoku, 108 0073 Tokyo, Japan
    Virchows Arch 446:270-7. 2005
    ..Putative microenvironmental inductive roles were postulated for the periglandular stromal fibroblasts to induce a metaplastic change toward the glands from pre-existing lung epithelial cells revealing adenomyomatous features...
  13. ncbi request reprint An ultrastructural and immunohistochemical study of microcystic meningioma with emphasis on matrix proteins and connexin 26 type gap junctions
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    Ultrastruct Pathol 28:247-53. 2004
    ....
  14. ncbi request reprint An ultrastructural and immunohistochemical study of elastofibroma: CD 34, MEF-2, prominin 2 (CD133), and factor XIIIa-positive proliferating fibroblastic stromal cells connected by Cx43-type gap junctions
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Minato ku, Tokyo, Japan
    Ultrastruct Pathol 31:209-19. 2007
    ..The elastofibromas might have arisen from stromal stem cell candidate populations of stromal fibroblastic cells (CD34(+), MEF2(+), prominin 2(CD133)(+), and factor XIIIa(+))...
  15. ncbi request reprint An immunohistochemical and ultrastructural study of pancreatic microcystic serous cyst adenoma with special reference to tumor-associated microvasculature and vascular endothelial growth factor in tumor cells
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    Ultrastruct Pathol 30:119-28. 2006
    ....
  16. ncbi request reprint An ultrastructural study of cutaneous panniculitis-like T-cell lymphoma: cytoplasmic granules and active cellular and cell-to-matrix interaction mimic cytotoxic T-cells
    Kazuto Yamazaki
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    Ultrastruct Pathol 26:185-90. 2002
    ....
  17. pmc Increased E2F-1 expression via tumour cell proliferation and decreased apoptosis are correlated with adverse prognosis in patients with squamous cell carcinoma of the oesophagus
    K Yamazaki
    Department of Pathology, Teikyo University, Ichihara Hospital, Ichihara, 3426 3 Anesaki, Ichihara City, Chiba 299 0111, Japan
    J Clin Pathol 58:904-10. 2005
    ..Recent studies show that E2F-1 also participates in apoptosis induction in a p53 dependent or independent manner. Despite its crucial role and paradoxical effects on cell turnover, the function of E2F-1 in human cancer is unclear...
  18. doi request reprint Hazard Evaluation Support System (HESS) for predicting repeated dose toxicity using toxicological categories
    Y Sakuratani
    Chemical Management Centre, National Institute of Technology and Evaluation, Tokyo, Japan
    SAR QSAR Environ Res 24:351-63. 2013
    ..This article describes the establishment of a category library and the associated HESS functions used to facilitate the mechanistically reasonable grouping of chemicals and their subsequent read-across...
  19. ncbi request reprint Axonal degeneration promotes abnormal accumulation of amyloid beta-protein in ascending gracile tract of gracile axonal dystrophy (GAD) mouse
    N Ichihara
    Department of Animal Models for Human Disease, National Institute of Neuroscience, Tokyo, Japan
    Brain Res 695:173-8. 1995
    ....
  20. ncbi request reprint Lipid-rich clear-cell hepatocellular carcinoma arising in non-alcoholic steatohepatitis in a patient with diabetes mellitus
    H Orikasa
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    J Submicrosc Cytol Pathol 33:195-200. 2001
    ....
  21. doi request reprint Mucosal microvilli in dry eye patients with chronic GVHD
    Y Tatematsu
    Department of Ophthalmology, The Keio University School of Medicine, 35 Shinanomachi Shinjuku ku, Tokyo, Japan
    Bone Marrow Transplant 47:416-25. 2012
    ..These may be important factors affecting the stability of the tear-film layer and its contribution to cGVHD-related dry eye...
  22. ncbi request reprint A unique early gastric tubular adenocarcinoma arising from a pre-existent carcinoid tumor in a patient with a more than 20-year history of type A gastritis: an immunohistochemical and ultrastructural study
    S Kikuyama
    Department of Surgery, Saiseikai Central Hospital, Tokyo, Japan
    J Submicrosc Cytol Pathol 34:109-14. 2002
    ..Ultrastructurally there were no amphicrine cells in the tumor, containing both endocrine granules and mucin droplets...
  23. ncbi request reprint Cardiac sarcoma showing bone formation and neurogenic markers: report of a case
    H Okita
    Department of Pathology, Saiseikai Central Hospital, Tokyo, Japan
    J Submicrosc Cytol Pathol 34:1-7. 2002
    ..Atrial sarcomas showing neural markers and bone formation are exceedingly rare, and this report adds a further exceptionally uncommon case to the literature...
  24. ncbi request reprint A significant role of stromal fibroblasts in rapidly progressive dry eye in patients with chronic GVHD
    Y Ogawa
    Departments of Ophthalmology and. Diagnostic Pathology, Institute for Advanced Medical Research, Tokyo, Japan
    Invest Ophthalmol Vis Sci 42:111-9. 2001
    ..In addition, it is likely that stromal fibroblasts are actively involved in the pathogenic process of chronic GVHD in the lacrimal gland by producing excessive extracellular matrix components...
  25. ncbi request reprint Anaplastic plasmacytoma with malignant pleural effusion lacking evidence of monoclonal gammopathy
    Takuya Aoki
    Department of Internal Medicine, Saiseikai Central Hospital, Tokyo, Japan
    Virchows Arch 441:154-8. 2002
    ..The study illustrates the need for a comprehensive array of techniques to distinguish such rare non-synthesizing and non-secretory plasmacytomas from lymphoma...
  26. ncbi request reprint Connexin 26 distribution in gap junctions between melanocytes in the human vestibular dark cell area
    M Masuda
    Department of Otorhinolaryngology, Keio University, School of Medicine, Tokyo, Japan
    Anat Rec 262:137-46. 2001
    ..This suggested that the melanocytes in the human vestibular organ may play a role in transporting material between the endolymph and perilymph...
  27. ncbi request reprint Gap junctions and nerve terminals among stromal cells in human fallopian tube ampullary mucosa
    K Yamazaki
    Department of Diagnostic Pathology, School of Medicine Keio University, Tokyo, Japan
    J Submicrosc Cytol Pathol 30:399-408. 1998
    ..Similarities to the unique anatomical unit referred to as the 'neuro-reticular complex' in bone marrow tissue (Yamazaki and Allen, 1990) are discussed...
  28. pmc Increased cyclin D1 expression in cancer of the ampulla of Vater: relevance to nuclear beta catenin accumulation and k-ras gene mutation
    K Yamazaki
    Department of Pathology, Teikyo University, Ichihara Hospital, Ichihara, 299 0111, Japan
    Mol Pathol 56:336-41. 2003
    ....
  29. ncbi request reprint Laparoscopic hepatectomy for extrahepatic growing tumor. Surgical strategy based on extrahepatic growing index
    S Takagi
    Second Department of Surgery, Toho University, School of Medicine, 6 11 1, Omori Nishi, Ota ku, Tokyo 143 8541, Japan
    Surg Endosc 16:1573-8. 2002
    ....
  30. pmc Cardiomyogenic differentiation in cardiac myxoma expressing lineage-specific transcription factors
    Hiroaki Kodama
    Cardiovascular Center, Saiseikai Central Hospital, Tokyo, Japan
    Am J Pathol 161:381-9. 2002
    ..These results support the concept that cardiac myxoma might arise from mesenchymal cardiomyocyte progenitor cells...
  31. ncbi request reprint Progressive degeneration of motor nerve terminals in GAD mutant mouse with hereditary sensory axonopathy
    H Miura
    Division of Degenerative Disease, National Institute of Neuroscience, NCNP, Tokyo, Japan
    Neuropathol Appl Neurobiol 19:41-51. 1993
    ....
  32. ncbi request reprint Expression of transcription factor E2F-1 in pancreatic ductal carcinoma: an immunohistochemical study
    Kazuto Yamazaki
    Department of Pathology, Teikyo University, Ichihara Hospital, Ichihara, Chiba, Japan
    Pathol Res Pract 199:23-8. 2003
    ..015). The present analysis seems to support the theory that E2F-1 is upregulated in cell cycle, and its expression reflects the effector function of G1/S progression as far as pancreatic ductal carcinoma is concerned...
  33. ncbi request reprint [F-18]Fluorodeoxyglucose positron emission tomography can predict pathological tumor stage and proliferative activity determined by Ki-67 in clinical stage IA lung adenocarcinomas
    Ken ichi Watanabe
    Department of Thoracic Surgery, Saiseikai Central Hospital, Tokyo, Japan
    Jpn J Clin Oncol 36:403-9. 2006
    ....
  34. ncbi request reprint Donor fibroblast chimerism in the pathogenic fibrotic lesion of human chronic graft-versus-host disease
    Yoko Ogawa
    Institute for Advanced Medical Research, Keio University School of Medicine, Shinanomachi, Tokyo, Japan
    Invest Ophthalmol Vis Sci 46:4519-27. 2005
    ..The current study was undertaken to investigate whether the increase in fibroblasts at the site of pathogenic fibrosis originated from transplanted donor cells in patients with chronic GVHD...
  35. ncbi request reprint Use of technetium-99m tin colloid for sentinel lymph node identification in non-small cell lung cancer
    Hiroaki Nomori
    Departments of Thoracic Surgery and Pathology, Saiseikai Central Hospital, Tokyo, Japan
    J Thorac Cardiovasc Surg 124:486-92. 2002
    ..To test the reliability of sentinel lymph node identification in non-small cell lung cancer, sentinel nodes were localized with a radioactive colloid in patients undergoing surgery...
  36. doi request reprint Categorization of nitrobenzenes for repeated dose toxicity based on adverse outcome pathways
    Y Sakuratani
    Chemical Management Center, National Institute of Technology and Evaluation, Tokyo, Japan
    SAR QSAR Environ Res 24:35-46. 2013
    ..As a result, a group of nitrobenzenes was defined as a single category for both haemolytic anaemia and liver effects, respectively, based on these AOPs...
  37. ncbi request reprint Protective effect of human urinary thrombomodulin on ischemia- reperfusion injury in the canine liver
    H Kaneko
    Second Department of Surgery, Toho University School of Medicine, Tokyo, Japan
    Eur Surg Res 32:87-93. 2000
    ..These findings suggest that administration of thrombomodulin inhibits endothelial cell injury and coagulopathy and offers protection from liver ischemia-reperfusion injury...
  38. ncbi request reprint Substance P-immunoreactive astrocytes in gracile sensory nervous tract of spinal cord in gracile axonal dystrophy mutant mouse
    K Yamazaki
    Division of Animal Models for Human Disease, National Institute of Neuroscience, NCNP, Tokyo, Japan
    Mol Chem Neuropathol 20:1-20. 1993
    ....
  39. ncbi request reprint Drosophila von Hippel-Lindau tumor suppressor complex possesses E3 ubiquitin ligase activity
    T Aso
    Department of Viral Oncology, Cancer Institute, Japanese Foundation for Cancer Research, 1 37 1 Kami Ikebukuro, Toshima ku, Tokyo, 170 8455, Japan
    Biochem Biophys Res Commun 276:355-61. 2000
    ..In addition, we provide evidence that hypoxia-inducible factor (HIF)-1alpha is the ubiquitination target of both human and Drosophila VHL complexes...
  40. doi request reprint Clinicopathologic study of a SNCA gene duplication patient with Parkinson disease and dementia
    T Obi
    Department of Neurology, Shizuoka Institute of Epilepsy and Neurological Disorders, Tokyo, Japan
    Neurology 70:238-41. 2008
  41. ncbi request reprint Hybrid carcinomas of the salivary glands: report of nine cases with a clinicopathologic, immunohistochemical, and p53 gene alteration analysis
    Toshitaka Nagao
    Department of Surgical Pathology, Tokyo Medical University Hospital, Tokyo, Japan
    Mod Pathol 15:724-33. 2002
    ..Therefore, there is the possibility that such molecular-genetic events take an integral part for inducing the transformation from histologically lower to higher grade tumor during the hybrid carcinoma genesis of the salivary glands...
  42. ncbi request reprint False-positive findings on [18F]FDG-PET caused by non-neoplastic cellular elements after neoadjuvant chemoradiotherapy for non-small cell lung cancer
    Takashi Ohtsuka
    Department of Thoracic Surgery, Saiseikai Central Hospital, Minato ku, Tokyo 108 0073, Japan
    Jpn J Clin Oncol 35:271-3. 2005
    ....
  43. ncbi request reprint Dying back type axonal degeneration of sensory nerve terminals in muscle spindles of the gracile axonal dystrophy (GAD) mutant mouse
    K Oda
    Division of Degenerative Disease, National Institute of Neuroscience, NCNP, Tokyo, Japan
    Neuropathol Appl Neurobiol 18:265-81. 1992
    ....
  44. ncbi request reprint Postmortem diagnosis of Fabry disease with acromegaly and a unique vasculopathy
    Masaki Takao
    Department of Pathology, Saiseikai Central Hospital, l 4 17 Mita, Minato ku, Tokyo, 108 0073, Japan
    Virchows Arch 451:721-7. 2007
    ....
  45. ncbi request reprint Atypical thymoma (WHO B3) with neuroendocrine differentiation: report of a case
    Junichi Shiraishi
    Department of Pathology, Japanese Red Cross Medical Center, 4 1 22 Hiroo, Tokyo 150 8935, Japan
    Virchows Arch 449:234-7. 2006
    ..This is a unique case of thymoma with neuroendocrine differentiation, and to the best of our knowledge this is the first such case ever reported...
  46. doi request reprint Intrathoracic lipomas: their clinicopathological behaviors are not as straightforward as expected
    Hiroyuki Sakurai
    Department of Thoracic Surgery, Saiseikai Central Hospital, Tokyo, Japan
    Ann Thorac Surg 86:261-5. 2008
    ..Intrathoracic lipomas are a type of deep-seated lipoma, unlike subcutaneous lipomas. Due to the rarity of intrathoracic lipomas, little is known about their clinicopathological features...
  47. doi request reprint Intrapulmonary localized fibrous tumor of the lung: a very unusual presentation
    Hiroyuki Sakurai
    Department of Thoracic Surgery, Saiseikai Central Hospital, Tokyo, Japan
    Ann Thorac Surg 86:1360-2. 2008
    ..We present here a rare case of entirely intrapulmonary localized fibrous tumor (ie, localized fibrous tumor of the lung), and we review the pertinent literature...
  48. ncbi request reprint A clinicopathologic case report on macular hole associated with von Hippel-Lindau disease: a novel ultrastructural finding of wormlike, wavy tangles of filaments
    Makoto Inoue
    Department of Ophthalmology, Keio University, 35 Shinanomachi, Shinjuku ku, 160 8582, Tokyo, Japan
    Graefes Arch Clin Exp Ophthalmol 242:881-6. 2004
    ..We describe a novel ultrastructural finding observed in an epiretinal membrane excised from a patient with von Hippel-Lindau disease...
  49. ncbi request reprint Keratocystoma of the parotid gland: a report of two cases of an unusual pathologic entity
    Toshitaka Nagao
    Department of Surgical Pathology, Tokyo Medical University Hospital, Tokyo, Japan
    Mod Pathol 15:1005-10. 2002
    ..We believe that this lesion represents a benign cystic neoplasm rather than a malignant tumor or pseudoneoplastic metaplastic condition. It is important to recognize that this peculiar benign tumor does originate from the salivary gland...
  50. ncbi request reprint Intrapulmonary schwannoma
    Takashi Ohtsuka
    Department of Thoracic Surgery, Saiseikai Central Hospital, Tokyo, Japan
    Jpn J Thorac Cardiovasc Surg 53:154-6. 2005
    ..Immunohistochemical staining demonstrated the presence of S-100 protein in the tumor cells. We present a case of intrapulmonary schwannoma and review 62 cases of primary schwannoma of the lung...
  51. ncbi request reprint Periductal area as the primary site for T-cell activation in lacrimal gland chronic graft-versus-host disease
    Yoko Ogawa
    Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 44:1888-96. 2003
    ..To examine immune processes in the lacrimal gland of patients with chronic graft-versus-host disease (cGVHD) by evaluating the expression of surface molecules associated with T-cell activation...
  52. ncbi request reprint Pulmonary metastasis 12 years after resection of thymoma with microscopic capsule invasion
    Hiroaki Nomori
    Department of Thoracic Surgery, Saiseikai Central Hospital, 1 4 17 Mita, Minato ku, Tokyo 108 0073, Japan
    Jpn J Clin Oncol 34:630-3. 2004
    ..Long-term follow-up is essential for the detection of recurrence after resection of a thymoma with microscopic capsular invasion, and surgery could be the best treatment for distant metastasis in case of resectable lesions...
  53. ncbi request reprint Postmortem diagnosis of "occult" Klinefelter syndrome in a patient with chronic renal disease and liver cirrhosis
    Kentaro Matsuoka
    Department of Pathology, School of Medicine, Keio University, and Saiseikai Central Hospital, Tokyo, Japan
    Arch Pathol Lab Med 126:359-61. 2002
    ..This report illustrates the value of postmortem laboratory investigations, particularly FISH for sex chromosomes and serum hormone analysis, for the demonstration of clinically uncertain or "occult" Klinefelter syndrome...
  54. ncbi request reprint Unique follicular carcinoma of the thyroid gland with extracellular deposition of amorphous globular structures mimicking an adenoid cystic pattern
    Kazuto Yamazaki
    Virchows Arch 443:690-2. 2003
  55. ncbi request reprint An ultrastructural and immunohistochemical study of a combined submucosal granular cell tumor and lipoma of the colon showing a unique nodule-in-nodule structure: putative implication of CD34 or prominin-2-positive stromal cells in its histopathogenesis
    Taisuke Mori
    Virchows Arch 449:137-9. 2006
  56. ncbi request reprint Microarray analysis of gene expression changes in mouse liver induced by peroxisome proliferator- activated receptor alpha agonists
    Kazuto Yamazaki
    Tsukuba Research Laboratories, Eisai Company, Ltd, 5 1 3, Tokodai, Tsukuba, Ibaraki, 300 2635, Japan
    Biochem Biophys Res Commun 290:1114-22. 2002
    ..This finding suggests that fenofibrate treatment may reduce plasma SAA concentration in patients with secondary amyloidosis...
  57. ncbi request reprint Expression of p21/WAF-1, status of apoptosis and p53 mutation in esophageal squamous cell carcinoma with HPV infection
    Makoto Hasegawa
    Department of Surgery, Ichihara Hospital Teikyo University, School of Medicine, Ichihara, Japan
    Pathol Int 52:442-50. 2002
    ..The data provide significant support for the hypothesis that HPV infection may play a crucial role in the oncogenesis of some ESCC...
  58. ncbi request reprint Sarcomatoid variant of salivary duct carcinoma: clinicopathologic and immunohistochemical study of eight cases with review of the literature
    Toshitaka Nagao
    Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 122:222-31. 2004
    ..6 months). These results indicate that sarcomatoid SDC is a highly aggressive tumor, similar to conventional SDC...
  59. ncbi request reprint Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults
    Hirohisa Tajima
    Department of Pharmacology and Neurosciences, Keio University School of Medicine, Shinanomachi, Shinjuku ku, Tokyo 160 8582, Japan
    Neurosci Lett 324:227-31. 2002
    ..HN immunoreactivity was also detected in an AD brain, but little in normal brains. This study suggests that HN peptide could be produced in vivo, and would provide a novel insight into the pathophysiology of AD...
  60. ncbi request reprint Ovarian fibroma (fibrothecoma) with extensive cystic degeneration: unusual MR imaging findings in two cases
    Tohru Takeshita
    Department of Radiology, Teikyo University School of Medicine, Ichihara Hospital, 3426 3 Anesaki, Ichihara, Chiba 299 0111, Japan
    Radiat Med 23:70-4. 2005
    ..It should be noted that ovarian fibromas (fibrothecomas) with extensive cystic degeneration are a rare exception to the rule that solid components in a cystic adnexal mass imply malignancy...
  61. pmc Deficits in spatial learning and motor coordination in ADAM11-deficient mice
    Eiki Takahashi
    Tsukuba Research Laboratories, Eisai Co, Ltd, 5 1 3 Tokodai, Tsukuba, Ibaraki 300 2635, Japan
    BMC Neurosci 7:19. 2006
    ..To elucidate the physiological functions of ADAM11, we generated ADAM11-deficient mice by means of gene targeting...
  62. ncbi request reprint Dedifferentiated adenoid cystic carcinoma: a clinicopathologic study of 6 cases
    Toshitaka Nagao
    Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Mod Pathol 16:1265-72. 2003
    ..Limited evidence suggests that p53 abnormalities in combination with HER-2/neu overexpression or loss of pRb expression may have a role in dedifferentiation of adenoid cystic carcinoma...