Feng Xue

Summary

Publications

  1. doi request reprint Evolution and pathogenesis of Leptospira spp.: lessons learned from the genomes
    Feng Xue
    Division of Basic Medical Microbiology, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital of Medical College, Zhejiang University, 310058 Hangzhou, Zhejiang, PR China
    Microbes Infect 11:328-33. 2009
  2. doi request reprint Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity
    Dongjiao Luo
    Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou, Zhejiang 310058, PR China
    Vaccine 28:243-55. 2009
  3. doi request reprint Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin
    Shijun Li
    Division of Basic Medical Microbiology, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital of Zhejiang University, Hangzhou, P R China
    Innate Immun 16:80-92. 2010
  4. pmc Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane
    Feng Xue
    State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, China
    PLoS Negl Trop Dis 4:e857. 2010
  5. pmc Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein
    Haiyan Dong
    Division of Basic Medical Microbiology, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou Zhejiang, PR China
    BMC Microbiol 8:223. 2008

Detail Information

Publications5

  1. doi request reprint Evolution and pathogenesis of Leptospira spp.: lessons learned from the genomes
    Feng Xue
    Division of Basic Medical Microbiology, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital of Medical College, Zhejiang University, 310058 Hangzhou, Zhejiang, PR China
    Microbes Infect 11:328-33. 2009
    ....
  2. doi request reprint Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity
    Dongjiao Luo
    Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, 388 Yuhangtang Road, Hangzhou, Zhejiang 310058, PR China
    Vaccine 28:243-55. 2009
    ..3% and 66.7% to 83.3% and 91.7%). The data suggest that all the rLipLs are the genus-specific superficial antigens of pathogenic Leptospira species and should be considered in designing universal vaccines against leptospirosis...
  3. doi request reprint Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin
    Shijun Li
    Division of Basic Medical Microbiology, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital of Zhejiang University, Hangzhou, P R China
    Innate Immun 16:80-92. 2010
    ..These data strongly suggest that the outcome for intracellular leptospires depends on differences among host macrophages, which may account for some of the differences in the severity of leptospirosis in humans and animals...
  4. pmc Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane
    Feng Xue
    State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, China
    PLoS Negl Trop Dis 4:e857. 2010
    ..Phagocytosis plays important roles in the innate immune responses to L. interrogans infection, and L. interrogans can evade the killing of phagocytes. However, little is known about the adaptation of L. interrogans during this process...
  5. pmc Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein
    Haiyan Dong
    Division of Basic Medical Microbiology, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou Zhejiang, PR China
    BMC Microbiol 8:223. 2008
    ..OmpL1, a transmembrane porin of pathogenic leptospires, was identified as a possible GP-Ag, but its sequence diversity and immune cross-reactivity among different serovars of pathogenic leptospires remains largely unknown...