Weiming Xu

Summary

Affiliation: London Biotech Ltd
Location: London, Uk
URL: Www.wxumac.demon.co.uk
Summary:
Biotechnology, signal transduction, cholesterol regulation, nanotechnology, nitric oxide, endoplamic reticulum, pcsk9, ldlr, cancer
Grants:
Anti-cancer antibody development, 2009-2012, Bayer Healthcare

Publications

  1. ncbi Localization of brain nitric oxide synthase (NOS) to human chromosome 12
    J Kishimoto
    Department of Neurobiology, AFRC, Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, United Kingdom
    Genomics 14:802-4. 1992
  2. ncbi The CCTTT polymorphism in the NOS2A gene is associated with dementia with Lewy bodies
    W Xu
    The Wolfson Institute for Biomedical Research, London, UK
    Neuroreport 11:297-9. 2000
  3. ncbi Nitric oxide: from a mysterious labile factor to the molecule of the Nobel Prize. Recent progress in nitric oxide research
    W M Xu
    Wolfson Institute for Biomedical Research, Rayne Institute, University College London
    Cell Res 8:251-8. 1998
  4. ncbi Molecular cloning and structural organization of the human inducible nitric oxide synthase gene (NOS2)
    W Xu
    MRC Molecular Neuroscience Group, Department of Neurobiology, Babraham Institute, Cambridge, UK
    Biochem Biophys Res Commun 219:784-8. 1996
  5. pmc Genetic evidence for the neuronal nitric oxide synthase gene (NOS1) as a susceptibility locus for infantile pyloric stenosis
    E Chung
    Department of Paediatrics, University College London Medical School, Rayne Institute, United Kingdom
    Am J Hum Genet 58:363-70. 1996
  6. ncbi Regional localization of the gene coding for human brain nitric oxide synthase (NOS1) to 12q24.2-->24.31 by fluorescent in situ hybridization
    W Xu
    Department of Neurobiology, AFRC Babraham Institute, Cambridge, UK
    Cytogenet Cell Genet 64:62-3. 1993
  7. ncbi Mapping of the genes encoding human inducible and endothelial nitric oxide synthase (NOS2 and NOS3) to the pericentric region of chromosome 17 and to chromosome 7, respectively
    W Xu
    Department of Neurobiology, AFRC, Babraham Institute, Cambrige, United Kingdom
    Genomics 21:419-22. 1994

Collaborators

Detail Information

Publications14

  1. ncbi Localization of brain nitric oxide synthase (NOS) to human chromosome 12
    J Kishimoto
    Department of Neurobiology, AFRC, Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, United Kingdom
    Genomics 14:802-4. 1992
    ..These data showed that the human brain nitric oxide synthase mapped within 12q14-qter on human chromosome 12...
  2. ncbi The CCTTT polymorphism in the NOS2A gene is associated with dementia with Lewy bodies
    W Xu
    The Wolfson Institute for Biomedical Research, London, UK
    Neuroreport 11:297-9. 2000
    ..Genotype frequencies in the DLB group also differed significantly from controls (p<0.012). These results suggest that variations in the NOS2A gene may predispose to the development of DLB...
  3. ncbi Nitric oxide: from a mysterious labile factor to the molecule of the Nobel Prize. Recent progress in nitric oxide research
    W M Xu
    Wolfson Institute for Biomedical Research, Rayne Institute, University College London
    Cell Res 8:251-8. 1998
    ..This review will focus on the nitric oxide synthase gene family and recent progress on molecular genetic analysis of NOS1, NOS2 and NOS3 genes...
  4. ncbi Molecular cloning and structural organization of the human inducible nitric oxide synthase gene (NOS2)
    W Xu
    MRC Molecular Neuroscience Group, Department of Neurobiology, Babraham Institute, Cambridge, UK
    Biochem Biophys Res Commun 219:784-8. 1996
    ..These results differ from the previously reported organization of the iNOS gene, where 26 exons were reported for the genomic structure of NOS2...
  5. pmc Genetic evidence for the neuronal nitric oxide synthase gene (NOS1) as a susceptibility locus for infantile pyloric stenosis
    E Chung
    Department of Paediatrics, University College London Medical School, Rayne Institute, United Kingdom
    Am J Hum Genet 58:363-70. 1996
    ..0006). These observations suggest that NOS1 is a susceptibility locus for PS...
  6. ncbi Regional localization of the gene coding for human brain nitric oxide synthase (NOS1) to 12q24.2-->24.31 by fluorescent in situ hybridization
    W Xu
    Department of Neurobiology, AFRC Babraham Institute, Cambridge, UK
    Cytogenet Cell Genet 64:62-3. 1993
    ..We report here the refinement of this localization to 12q24.2-->24.31 by fluorescent in situ hybridization...
  7. ncbi Mapping of the genes encoding human inducible and endothelial nitric oxide synthase (NOS2 and NOS3) to the pericentric region of chromosome 17 and to chromosome 7, respectively
    W Xu
    Department of Neurobiology, AFRC, Babraham Institute, Cambrige, United Kingdom
    Genomics 21:419-22. 1994
    ..Fluorescence in situ hybridization using a NOS2 probe gave several signals in the 17p11-q11 pericentromeric region...