Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinomaWen Hua Xiao
Department of Oncology, 304th Hospital of PLA, Beijing 100037, China
World J Gastroenterol 10:376-80. 2004
..To analyze the genetic and epigenetic alterations of RUNX3 gene, a potential putative tumor suppressor gene, in hepatocellular carcinoma (HCC)...
Effect of 5-aza-2'-deoxycytidine on immune-associated proteins in exosomes from hepatomaWen Hua Xiao
Department of Oncology, First Affiliated Hospital, Chinese PLA General Hospital, Beijing 100048, China
World J Gastroenterol 16:2371-7. 2010
..To study the effect of 5-aza-2'-deoxycytidine (5-aza-CdR) on heat shock protein 70 (HSP70), human leucocyte antigen-I (HLA-I) and NY-ESO-1 proteins in exosomes produced by hepatoma cells, HepG2 and Hep3B...
[Improvement and application of methylation-specific polymerase chain reaction]Wen Hua Xiao
Department of Oncology, The 304th Hospital, General Military Hospital, Beijing 100 037, P R China
Ai Zheng 23:1354-6. 2004
..This study was to adopt the improved MSP to detect methylation state of RUNX3 gene in hepatocellular carcinoma (HCC)...
[Effects of 5-aza-2'-deoxycytidine on the amount of exosomes and secreted immuno-associated proteins by hepatoma cells]- Sanrengaowa
Dept of Oncology, The First Affiliated Hospital, Chinese PLA General Hospital, Beijing 100048, China
Zhonghua Zhong Liu Za Zhi 31:495-9. 2009
..To investigate the effects of 5-Aza-deoxycytidine (5-Aza-CdR) on the amount of exosomes and immuno-associated proteins produced in hepatoma HepG2 and Hep3B cells...
[Histone deacetylase inhibitor MS-275 treatment alters immune molecule content and categories in hepatocarcinoma exosomes]Qiu wen Li
Department of Oncology, The First Affiliated Hospital, Chinese PLA General Hospital, Beijing 100048, China
Zhonghua Gan Zang Bing Za Zhi 20:231-5. 2012
..To investigate the effects of the histone deacetylase inhibitor, MS-275, on the immune molecule content and categories in hepatocarcinoma exosomes...
Reversal of multidrug resistance in renal cell carcinoma by short hairpin RNA targeting MDR1 geneYi Xin Hao
Department of Oncology, First Affiliated Hospital of the People s Liberation Army General Hospital, Beijing 100048, China
Chin Med J (Engl) 125:2741-5. 2012
..This study aimed to determine the effct of RNA interference (RNAi) on the reversal of MDR in human RCC...
[Prophylactic recombinant human thrombopoietin treatment alleviates chemotherapy- induced thrombocytopenia in tumor patients]Qiuwen Li
Department of Oncology, First Affiliated Hospital of General Hospital of PLA, Beijing 100048, China
Nan Fang Yi Ke Da Xue Xue Bao 32:1064-6. 2012
..To assess the efficacy of prophylactic treatment with recombinant human thrombopoietin (rhTPO) on chemotherapy-induced thrombocytopenia in tumor patients...
[Advanced dermatofibrosarcoma protuberans treated with imatinib mesylate]Jian Hua Zhu
Department of Chemotherapy, the First Affiliated Hospital of People s Liberation Army General Hospital, Beijing 100048, China
Zhonghua Zhong Liu Za Zhi 33:470-2. 2011
..To evaluate the efficacy, side effects and toxicity of imatinib mesylate in the treatment of patients with locally advanced and/or metastatic dermatofibrosarcoma protuberans (DFSP)...
Differential expression of Rab27A/B correlates with clinical outcome in hepatocellular carcinomaWei wei Dong
Department of Oncology, The First Affiliated Hospital, The General Hospital of Chinese People s Liberation Army, Beijing 100048, China
World J Gastroenterol 18:1806-13. 2012
..To investigate the association of Rab27A and Rab27B expression with clinicopathological characteristics and prognosis of hepatocellular carcinoma (HCC)...
[Effect of Fluorouracil-inducible GM-CSF gene therapy regulated by Egr-1 promoter on chemotherapeutic hematopoietic damage of tumor-bearing mice]Nan Du
First Affiliated Hospital of General PLA Hospital, Beijing 100037, China
Zhonghua Yi Xue Za Zhi 89:1281-6. 2009
..In order to explore the regulating effects of Egr-1 promoter sequences in transcriptional targeting by 5-fluorouracil (5-Fu) on the expression of hematopoietic growth factor genes...
[Analysis of methylation and loss of heterozygosity of RUNX3 gene in hepatocellular carcinoma and its clinical significance]Wen-hua Xiao
Department of Oncology, 304 Hospital of PLA, Beijing 100037, China
Zhonghua Gan Zang Bing Za Zhi 12:227-30. 2004
..CONCLUSION: High frequent hypermethylation and LOH of RUNX3 gene were found in HCC. Aberrant RUNX3 gene may play an important role in the development of HCC...