Genomes and Genes


Sun Xiaofang



  1. Yu Y, Gao Q, Zhao H, Li R, Gao J, Ding T, et al. Ascorbic acid improves pluripotency of human parthenogenetic embryonic stem cells through modifying imprinted gene expression in the Dlk1-Dio3 region. Stem Cell Res Ther. 2015;6:69 pubmed publisher
    ..The Dlk1-Dio3 imprinting gene cluster distinguishes the differentiation ability of hpESCs. Moreover, modification by ascorbic acid may facilitate application of hpESCs to clinical settings in the future by enhancing their pluripotency. ..
  2. Yingjun X, Zhiyang H, Linhua L, Fangming S, Linhuan H, Jinfeng T, et al. Chromosomal uniparental disomy 16 and fetal intrauterine growth restriction. Eur J Obstet Gynecol Reprod Biol. 2017;211:1-7 pubmed publisher
    ..Considering UPD mechanism of potential impact on the function of the placenta, the genetic composition of chromosome 16, and the information previous literature reports, we have reason to believe that UPD16 correlates with IUGR. ..
  3. Li H, Wan R, Tang L, Liu S, Zhao Q, Gao M, et al. Alteration of Scn3a expression is mediated via CpG methylation and MBD2 in mouse hippocampus during postnatal development and seizure condition. Biochim Biophys Acta. 2015;1849:1-9 pubmed publisher
    ..Taken together, these findings suggest that CpG methylation and MBD2 are involved in altering Scn3a expression during postnatal development and seizure condition. ..
  4. Yingjun X, Haiming Y, Mingbang W, Liangying Z, Jiaxiu Z, Bing S, et al. Copy number variations independently induce autism spectrum disorder. Biosci Rep. 2017;37: pubmed publisher
    ..With the strategy of our study, we could find the ASDs candidate genes by CNV data and review certain pathogenesis of this disorder. Those CNVs were associated with ASD and they may contribute to ASD by affecting the ASD-related genes. ..