Jen Leih Wu



  1. Kung H, Evensen Ã, Hong J, Kuo C, Tso C, Ngou F, et al. Interferon regulatory factor-1 (IRF-1) is involved in the induction of phosphatidylserine receptor (PSR) in response to dsRNA virus infection and contributes to apoptotic cell clearance in CHSE-214 cell. Int J Mol Sci. 2014;15:19281-306 pubmed publisher
  2. Pan C, Chen J, Chen T, Wu J, Hui C, Chen J. Piscidin is highly active against carbapenem-resistant Acinetobacter baumannii and NDM-1-producing Klebsiella pneumonia in a systemic Septicaemia infection mouse model. Mar Drugs. 2015;13:2287-305 pubmed publisher
  3. Wu C, Li B, Wu J, Hui C. Mechanism and Aquaculture Application of Teleost Enzymes Adapted at Low Temperature. Adv Food Nutr Res. 2016;79:117-136 pubmed publisher
    ..Furthermore, this information may create a possible explanation of fish physiological and biochemical evolution route and construct an appropriate strategy to overcome the climate change. ..
  4. Chen H, Liu W, Wu S, Chiou P, Li Y, Chen Y, et al. RIG-I specifically mediates group II type I IFN activation in nervous necrosis virus infected zebrafish cells. Fish Shellfish Immunol. 2015;43:427-35 pubmed publisher
    ..Taken together, our results indicate that RIG-I plays an essential role in zebrafish group II type I IFN induction and the inflammatory response to NNV infection. ..
  5. Cheng C, Huang S, Wu C, Gong H, Ken C, Hu S, et al. Transgenic expression of omega-3 PUFA synthesis genes improves zebrafish survival during Vibrio vulnificus infection. J Biomed Sci. 2015;22:103 pubmed publisher
    ..Fadsd6 and Elvol5a transgenic zebrafish are more resistant to V. vulnificus infection, and enhance survival by diminishing the attendant inflammatory response. ..
  6. Huang S, Cheng C, Chen J, Gong H, Liu W, Wu J. Inducible liver-specific overexpression of gankyrin in zebrafish results in spontaneous intrahepatic cholangiocarcinoma and hepatocellular carcinoma formation. Biochem Biophys Res Commun. 2017;490:1052-1058 pubmed publisher
    ..Herein, we demonstrate an excellent zebrafish model for liver cancers that will be useful for studying the molecular mechanisms of tumorgenesis. ..