Genomes and Genes


Bin Wu



  1. Wu B, Huang J, Zhang L, Kasukurthi M, Huang F, Bian J, et al. An integrative approach to investigate the association among high-sensitive C-reactive protein, body fat mass distribution, and other cardiometabolic risk factors in young healthy women. Methods. 2018;145:60-66 pubmed publisher
    ..Discovery 2: Chronic inflammation may involve in adipocyte-cytokine interaction underlying the metabolic derangement in healthy young women. ..
  2. Huang J, Eilbeck K, Smith B, Blake J, DOU D, Huang W, et al. The development of non-coding RNA ontology. Int J Data Min Bioinform. 2016;15:214-232 pubmed
    ..By providing a formally defined ncRNA controlled vocabulary, the NCRO aims to fill a specific and highly needed niche in semantic annotation of large amounts of ncRNA biological and clinical data. ..
  3. Wu B, Miller D. Involvement of MicroRNAs in Diabetes and Its Complications. Methods Mol Biol. 2017;1617:225-239 pubmed publisher
    ..The roles of miRNAs in the development of diabetic complications are also discussed. Modulating miRNA expression, by either upregulation or inhibition, holds a promise as a strategy for treating this metabolic disease. ..
  4. Zhang L, Miller D, Yang Q, Wu B. MicroRNA Regulatory Networks as Biomarkers in Obesity: The Emerging Role. Methods Mol Biol. 2017;1617:241-260 pubmed publisher
    ..MiRNAs may play an important part in regulating metabolic functions in adipose tissues and, by extension, obesity and its associated disorders. Consequently, they may be potential candidates for therapeutic targets and biomarkers. ..
  5. Zhang L, Li R, He J, Yang Q, Wu Y, Huang J, et al. Co-expression analysis among microRNAs, long non-coding RNAs, and messenger RNAs to understand the pathogenesis and progression of diabetic kidney disease at the genetic level. Methods. 2017;124:46-56 pubmed publisher
    ..We conducted fully transparent, rigorously designed experiments. Our robust and reproducible results identified hsa-miR-223-3p as a candidate novel biomarker performing important roles in DKD disease process. ..