Margaret E Wright

Summary

Publications

  1. ncbi request reprint Effects of alpha-tocopherol and beta-carotene supplementation on upper aerodigestive tract cancers in a large, randomized controlled trial
    Margaret E Wright
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, USA
    Cancer 109:891-8. 2007
  2. ncbi request reprint Higher baseline serum concentrations of vitamin E are associated with lower total and cause-specific mortality in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study
    Margaret E Wright
    Nutritional Epidemiology Branch and the Genetic Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Am J Clin Nutr 84:1200-7. 2006
  3. pmc Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
    J Nutr 142:866-71. 2012
  4. ncbi request reprint Serum and dietary vitamin E in relation to prostate cancer risk
    Stephanie J Weinstein
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:1253-9. 2007
  5. pmc Serum insulin, glucose, indices of insulin resistance, and risk of prostate cancer
    Demetrius Albanes
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 3044, Bethesda, MD 20892 7242, USA
    J Natl Cancer Inst 101:1272-9. 2009
  6. ncbi request reprint Supplemental and dietary vitamin E intakes and risk of prostate cancer in a large prospective study
    Margaret E Wright
    Divisions of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 16:1128-35. 2007
  7. ncbi request reprint Serum alpha-tocopherol and gamma-tocopherol in relation to prostate cancer risk in a prospective study
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    J Natl Cancer Inst 97:396-9. 2005
  8. ncbi request reprint A prospective investigation of height and prostate cancer risk
    Jacqueline S P Sequoia
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, EPS 3044, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 15:2174-8. 2006
  9. ncbi request reprint Multivitamin use and risk of prostate cancer in the National Institutes of Health-AARP Diet and Health Study
    Karla A Lawson
    Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 99:754-64. 2007
  10. ncbi request reprint Estimated urine pH and bladder cancer risk in a cohort of male smokers (Finland)
    Margaret E Wright
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
    Cancer Causes Control 16:1117-23. 2005

Detail Information

Publications18

  1. ncbi request reprint Effects of alpha-tocopherol and beta-carotene supplementation on upper aerodigestive tract cancers in a large, randomized controlled trial
    Margaret E Wright
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, USA
    Cancer 109:891-8. 2007
    ..Although smoking and alcohol consumption are the major risk factors for upper aerodigestive tract cancers, observational studies indicate a protective role for fruits, vegetables, and antioxidant nutrients...
  2. ncbi request reprint Higher baseline serum concentrations of vitamin E are associated with lower total and cause-specific mortality in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study
    Margaret E Wright
    Nutritional Epidemiology Branch and the Genetic Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Am J Clin Nutr 84:1200-7. 2006
    ..Little is known, however, about the relation between mortality and circulating concentrations of vitamin E resulting from dietary intake, low-dose supplementation, or both...
  3. pmc Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
    J Nutr 142:866-71. 2012
    ..g., α-tocopherol) under supplementation conditions improves our understanding of the biological determinants of these nutritional exposures and their associations with cancer etiology...
  4. ncbi request reprint Serum and dietary vitamin E in relation to prostate cancer risk
    Stephanie J Weinstein
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:1253-9. 2007
    ..In summary, higher prediagnostic serum concentrations of alpha-tocopherol, but not dietary vitamin E, was associated with lower risk of developing prostate cancer, particularly advanced prostate cancer...
  5. pmc Serum insulin, glucose, indices of insulin resistance, and risk of prostate cancer
    Demetrius Albanes
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 3044, Bethesda, MD 20892 7242, USA
    J Natl Cancer Inst 101:1272-9. 2009
    ..The mitogenic and growth-stimulatory effects of insulin-like growth factors appear to play a role in prostate carcinogenesis, yet any direct association of circulating insulin levels and risk of prostate cancer remains unclear...
  6. ncbi request reprint Supplemental and dietary vitamin E intakes and risk of prostate cancer in a large prospective study
    Margaret E Wright
    Divisions of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 16:1128-35. 2007
    ..The potential benefit of gamma-tocopherol for prostate cancer prevention deserves further attention...
  7. ncbi request reprint Serum alpha-tocopherol and gamma-tocopherol in relation to prostate cancer risk in a prospective study
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    J Natl Cancer Inst 97:396-9. 2005
    ..Participants with higher circulating concentrations of the major vitamin E fractions, alpha-tocopherol and gamma-tocopherol, had similarly lower prostate cancer risk...
  8. ncbi request reprint A prospective investigation of height and prostate cancer risk
    Jacqueline S P Sequoia
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, EPS 3044, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 15:2174-8. 2006
    ..02 (1.37-2.97); P(trend) = 0.0008, P(interaction) = 0.002]. Our study provides additional evidence that increased height is a risk factor for prostate cancer and suggests that taller men are particularly susceptible to advanced disease...
  9. ncbi request reprint Multivitamin use and risk of prostate cancer in the National Institutes of Health-AARP Diet and Health Study
    Karla A Lawson
    Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 99:754-64. 2007
    ..Multivitamin supplements are used by millions of Americans because of their potential health benefits, but the relationship between multivitamin use and prostate cancer is unclear...
  10. ncbi request reprint Estimated urine pH and bladder cancer risk in a cohort of male smokers (Finland)
    Margaret E Wright
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
    Cancer Causes Control 16:1117-23. 2005
    ....
  11. pmc Vitamin E intake and risk of esophageal and gastric cancers in the NIH-AARP Diet and Health Study
    Sarah Carman
    NEB DCEG, National Cancer Institute, Bethesda, MD 20892 7232, USA
    Int J Cancer 125:165-70. 2009
    ..An increase of 71 mg/day (half the interquartile range) in supplemental vitamin E had an hazard ratio (95% confidence interval) of 0.92 (0.85-1.00) and the p value for trend in the quartile analysis was 0.015...
  12. ncbi request reprint History of diabetes mellitus and subsequent prostate cancer risk in the NIH-AARP Diet and Health Study
    Brook A Calton
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Institutes of Health, Department of Health and Human Services, 6120 Executive Blvd, EPS MSC 7232, Bethesda, MD 20892, USA
    Cancer Causes Control 18:493-503. 2007
    ..A history of diabetes has been hypothesized to decrease prostate cancer risk, but studies have not always considered confounding or effect modification by dietary or lifestyle factors...
  13. pmc Genome-wide association study identifies common variants associated with circulating vitamin E levels
    Jacqueline M Major
    Division of Cancer Epidemiology and Genetics and Core Genotyping Facility, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    Hum Mol Genet 20:3876-83. 2011
    ..In one of the two male GWAS cohorts (n= 992), no SNPs were significantly associated with gamma-tocopherol concentrations after including data from the replication sample for 71 independent SNPs with P< 1 × 10(-4) identified...
  14. ncbi request reprint Arsenic concentrations in prediagnostic toenails and the risk of bladder cancer in a cohort study of male smokers
    Dominique S Michaud
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Epidemiol 160:853-9. 2004
    ..13, 95% confidence interval: 0.70, 1.81 for the highest vs. lowest quartile). These findings suggest that low-level arsenic exposure is unlikely to explain a substantial excess risk of bladder cancer...
  15. ncbi request reprint Prospective study of adiposity and weight change in relation to prostate cancer incidence and mortality
    Margaret E Wright
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer 109:675-84. 2007
    ..Adiposity has been linked inconsistently with prostate cancer, and few studies have evaluated whether such associations vary by disease aggressiveness...
  16. ncbi request reprint Development of a comprehensive dietary antioxidant index and application to lung cancer risk in a cohort of male smokers
    Margaret E Wright
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    Am J Epidemiol 160:68-76. 2004
    ..14), 0.91 (95% CI: 0.79, 1.05), 0.79 (95% CI: 0.68, 0.92), and 0.84 (95% CI: 0.72, 0.98) (p for trend = 0.002). These findings support the hypothesis that a combination of dietary antioxidants reduces lung cancer risk in male smokers...
  17. pmc Intakes of fruit, vegetables, and specific botanical groups in relation to lung cancer risk in the NIH-AARP Diet and Health Study
    Margaret E Wright
    Department of Pathology MC 847, College of Medicine, University of Illinois at Chicago, 840 South Wood Street, Room 130, Chicago, IL 60612, USA
    Am J Epidemiol 168:1024-34. 2008
    ..06). These results provide support for a protective role of specific botanical subgroups of fruits and vegetables in lung cancer prevention in men, although the findings could also be due to residual confounding by smoking or chance...
  18. ncbi request reprint Dietary carotenoids, vegetables, and lung cancer risk in women: the Missouri women's health study (United States)
    Margaret E Wright
    Department of Epidemiology, and Public Health, Yale University School of Medicine, New Haven, CT 05620 8034, USA
    Cancer Causes Control 14:85-96. 2003
    ..To examine the effect of specific dietary carotenoids and their primary plant food sources on lung cancer risk in a population-based case-control study of women...