Emerging disease of amphibians cured by elevated body temperatureDouglas C Woodhams
School of Tropical Biology, James Cook University, Townsville, Queensland 4811, Australia
Dis Aquat Organ 55:65-7. 2003
....
Immune evasion or avoidance: fungal skin infection linked to reduced defence peptides in Australian green-eyed treefrogs, Litoria serrataDouglas C Woodhams
Department of Ecology and Evolutionary Biology, University of Colorado, N122 Ramaley, 334 UCB, Boulder, CO 80309 0334, USA
Fungal Biol 116:1203-11. 2012
..Immune evasion therefore may contribute to the pathogenesis of chytridiomycosis and a mechanistic understanding of this fungal strategy may lead to improved methods of disease control...
Tolerance of fungal infection in European water frogs exposed to Batrachochytrium dendrobatidis after experimental reduction of innate immune defensesDouglas C Woodhams
Institute of Evolutionary Biology and Environmental Studies, University of Zurich, Winterthurerstrasse 190, Zurich, CH 8057, Switzerland
BMC Vet Res 8:197. 2012
..lessonae) collected in the field with their natural microbiota intact were exposed to Bd after experimental reduction of microbiota, skin peptides, both, or neither to determine the relative contributions of these defenses...
- Treatment of amphibians infected with chytrid fungus: learning from failed trials with itraconazole, antimicrobial peptides, bacteria, and heat therapy
Douglas C Woodhams
Institute of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, Switzerland
Dis Aquat Organ 98:11-25. 2012
..Learning from 'failed treatments' is essential for the timely achievement of conservation goals and one of the primary aims for a publicly accessible treatment database under development...
- Mitigating amphibian disease: strategies to maintain wild populations and control chytridiomycosis
Douglas C Woodhams
Institute of Evolutionary Biology and Environmental Studies, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland
Front Zool 8:8. 2011
..abstract:..
- Chytridiomycosis and amphibian population declines continue to spread eastward in Panama
Douglas C Woodhams
Institute of Zoology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
Ecohealth 5:268-74. 2008
..Therefore, development of new management strategies and increased precautions for tourism, recreation, and biology are urgently needed...
- Life-history trade-offs influence disease in changing climates: strategies of an amphibian pathogen
Douglas C Woodhams
Department of Microbiology and Immunology, Vanderbilt University, Nashville, Tennessee 37232, USA
Ecology 89:1627-39. 2008
..These results demonstrate that B. dendrobatidis populations can grow at high rates across a broad range of environmental temperatures and help to explain why it is so successful in cold montane environments...
- Amphibian immune defenses against chytridiomycosis: impacts of changing environments
Louise A Rollins-Smith
Department of Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
Integr Comp Biol 51:552-62. 2011
..We also briefly review what is known about the impacts of temperature, environmental chemicals, and stress on the host-pathogen interactions and suggest future directions for research...
- Immune defenses against Batrachochytrium dendrobatidis, a fungus linked to global amphibian declines, in the South African clawed frog, Xenopus laevis
Jeremy P Ramsey
Department of Microbiology and Immunology, A 5301 Medical Center North, Vanderbilt University, Nashville, TN 37232, USA
Infect Immun 78:3981-92. 2010
..dendrobatidis. These data strongly suggest that both innate and adaptive immune defenses are involved in the resistance of X. laevis to lethal B. dendrobatidis infections...
- Antimicrobial peptide defenses of the mountain yellow-legged frog (Rana muscosa)
Louise A Rollins-Smith
Department of Microbiology and Immunology, Vanderbilt University, A 5301 Medical Center North, Nashville, TN 37232, USA
Dev Comp Immunol 30:831-42. 2006
..dendrobatidis in nature. Possible differences in the antimicrobial peptide repertoires and life history traits of the two species that may account for differences in susceptibility are discussed...
- Predicted disease susceptibility in a Panamanian amphibian assemblage based on skin peptide defenses
Douglas C Woodhams
Department of Microbiology and Immunology, Vanderbilt University, A5301 Medical Center North, Nashville, Tennessee 37232, USA
J Wildl Dis 42:207-18. 2006
..This supports the hypothesis that B. dendrobatidis is a generalist pathogen and that species possessing an innate immunologic defense at the time of disease emergence are more likely to survive...
- Sink or swim: a test of tadpole behavioral responses to predator cues and potential alarm pheromones from skin secretions
Nino Maag
Institute of Evolutionary Biology and Environmental Studies, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
J Comp Physiol A Neuroethol Sens Neural Behav Physiol 198:841-6. 2012
..Comparative behavioral physiology of amphibian alarm responses may elucidate functional trade-offs in pheromone production and the evolution of chemical communication...
