Dale Woodbury

Summary

Publications

  1. ncbi request reprint Novel structure of the human GDNF gene
    D Woodbury
    Department of Neuroscience and Cell Biology, UMDNJ Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
    Brain Res 803:95-104. 1998
  2. ncbi request reprint Adult rat and human bone marrow stromal cells differentiate into neurons
    D Woodbury
    Department of Neuroscience and Cell Biology, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Neurosci Res 61:364-70. 2000
  3. ncbi request reprint Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis
    Dale Woodbury
    Department of Neuroscience and Cell Biology, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Neurosci Res 69:908-17. 2002
  4. ncbi request reprint Long-term cryopreserved amniocytes retain proliferative capacity and differentiate to ectodermal and mesodermal derivatives in vitro
    D Woodbury
    Ira B Black Center for Stem Cell Research, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Mol Reprod Dev 73:1463-72. 2006
  5. ncbi request reprint Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and glia
    Thomas M Coyne
    The Ira B Black Center for Stem Cell Rersearch and Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ 08854 5635, USA
    Stem Cells 24:2483-92. 2006
  6. ncbi request reprint Adult bone marrow stromal cells in the embryonic brain: engraftment, migration, differentiation, and long-term survival
    Guillermo Muñoz-Elias
    Department of Neuroscience and Cell Biology and the Stem Cell Research Center, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854 5635, USA
    J Neurosci 24:4585-95. 2004
  7. ncbi request reprint Isolation, characterization, and differentiation of stem cells derived from the rat amniotic membrane
    Akiva J Marcus
    The Ira B Black Center for Stem Cell Research, Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ 08854 5635, USA
    Differentiation 76:130-44. 2008
  8. ncbi request reprint Disparate host response and donor survival after the transplantation of mesenchymal or neuroectodermal cells to the intact rodent brain
    Thomas M Coyne
    Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ, USA
    Transplantation 84:1507-16. 2007
  9. ncbi request reprint Adult rat bone marrow stromal cells express genes associated with dopamine neurons
    Brian C Kramer
    Department of Neuroscience and Cell Biology, UMDNJ Robert Wood Johnson Medical School, 683 Hoes Lane Piscataway, NJ 08854, USA
    Biochem Biophys Res Commun 343:1045-52. 2006
  10. ncbi request reprint Marrow stromal cells, mitosis, and neuronal differentiation: stem cell and precursor functions
    Guillermo Muñoz-Elias
    University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway 08854, USA
    Stem Cells 21:437-48. 2003

Detail Information

Publications13

  1. ncbi request reprint Novel structure of the human GDNF gene
    D Woodbury
    Department of Neuroscience and Cell Biology, UMDNJ Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
    Brain Res 803:95-104. 1998
    ..Importantly, we demonstrate that the hGDNF gene utilizes a promoter distinct from that identified in the rodent GDNF gene, a finding with ramifications for Parkinson's disease and ALS research...
  2. ncbi request reprint Adult rat and human bone marrow stromal cells differentiate into neurons
    D Woodbury
    Department of Neuroscience and Cell Biology, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Neurosci Res 61:364-70. 2000
    ..Consequently, adult marrow stromal cells can be induced to overcome their mesenchymal commitment and may constitute an abundant and accessible cellular reservoir for the treatment of a variety of neurologic diseases...
  3. ncbi request reprint Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis
    Dale Woodbury
    Department of Neuroscience and Cell Biology, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Neurosci Res 69:908-17. 2002
    ..Our observations suggest that MSCs are already multidifferentiated and that neural differentiation comprises quantitative modulation of gene expression rather than simple on-off switching of neural-specific genes...
  4. ncbi request reprint Long-term cryopreserved amniocytes retain proliferative capacity and differentiate to ectodermal and mesodermal derivatives in vitro
    D Woodbury
    Ira B Black Center for Stem Cell Research, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Mol Reprod Dev 73:1463-72. 2006
    ..Retention of this plasticity through decades of cryopreservation suggests that amniocytes might be candidates for future cell-based therapies...
  5. ncbi request reprint Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and glia
    Thomas M Coyne
    The Ira B Black Center for Stem Cell Rersearch and Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ 08854 5635, USA
    Stem Cells 24:2483-92. 2006
    ..Moreover, use of the traditional cell labels BrdU and BBZ may provide a misleading index of donor survival and differentiation after transplantation...
  6. ncbi request reprint Adult bone marrow stromal cells in the embryonic brain: engraftment, migration, differentiation, and long-term survival
    Guillermo Muñoz-Elias
    Department of Neuroscience and Cell Biology and the Stem Cell Research Center, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854 5635, USA
    J Neurosci 24:4585-95. 2004
    ..In the cortex and bulb, 98.6 and 77.3% were NeuN (neuronal-specific nuclear protein) positive, respectively. Our observations suggest that transplanted adult MSCs differentiate in a regionally and temporally specific manner...
  7. ncbi request reprint Isolation, characterization, and differentiation of stem cells derived from the rat amniotic membrane
    Akiva J Marcus
    The Ira B Black Center for Stem Cell Research, Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ 08854 5635, USA
    Differentiation 76:130-44. 2008
    ..In sum, our data suggest that ADSCs and derived clonal lines are capable of long-term self-renewal and multidifferentiation, fulfilling all the criteria of a stem-cell population...
  8. ncbi request reprint Disparate host response and donor survival after the transplantation of mesenchymal or neuroectodermal cells to the intact rodent brain
    Thomas M Coyne
    Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ, USA
    Transplantation 84:1507-16. 2007
    ..To determine the future utility of these cells in neural transplantation, we have now performed a systematic analysis of MSC transplantation to the brain...
  9. ncbi request reprint Adult rat bone marrow stromal cells express genes associated with dopamine neurons
    Brian C Kramer
    Department of Neuroscience and Cell Biology, UMDNJ Robert Wood Johnson Medical School, 683 Hoes Lane Piscataway, NJ 08854, USA
    Biochem Biophys Res Commun 343:1045-52. 2006
    ..The expression of genes that are associated with the development and survival of dopamine neurons suggests a potential role for these cells in the treatment of Parkinson's disease...
  10. ncbi request reprint Marrow stromal cells, mitosis, and neuronal differentiation: stem cell and precursor functions
    Guillermo Muñoz-Elias
    University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway 08854, USA
    Stem Cells 21:437-48. 2003
    ..Apparently, MSCs may directly differentiate into neurons without passing through a mitotic stage, suggesting that distinctions among stem cells, progenitors, and precursors are more flexible than formerly recognized...
  11. doi request reprint Fetal stem cells from extra-embryonic tissues: do not discard
    Akiva J Marcus
    The Ira B Black Center for Stem Cell Research and the Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ 08854 5635, USA
    J Cell Mol Med 12:730-42. 2008
    ..In this review we summarize recent work examining the plasticity and clinical potential of fetal stem cells isolated from extra-embryonic tissues...
  12. doi request reprint Fate of amnion-derived stem cells transplanted to the fetal rat brain: migration, survival and differentiation
    A J Marcus
    The Ira B Black Center for Stem Cell Research and the Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway NJ 08854 5635, USA
    J Cell Mol Med 12:1256-64. 2008
    ..Long-term survival may suggest utility in the treatment of disorders where differentiation to a neural cell type is not required for clinical benefit...
  13. pmc Efficient method for generating nuclear fractions from marrow stromal cells
    Dale Woodbury
    Ira B Black Center for Stem Cell Research, Department of Neuroscience and Cell Biology, UMDNJ, Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ, 08854, USA
    Cytotechnology 58:77-84. 2008
    ..This simple method for isolation of highly purified nuclear fractions from stem cell populations will allow rigorous examination of nuclear proteins critical for differentiation...