Klaus K Witte

Summary

Publications

  1. ncbi request reprint Marine polyunsaturated fatty acids in heart failure. Are the theoretical benefits matched by the clinical data?
    Klaus K A Witte
    Division of Cardiovascular and Diabetes Research, University of Leeds and Leeds General Infirmary, Leeds, United Kingdom
    Pol Arch Med Wewn 119:162-9. 2009
  2. ncbi request reprint Deployment of left ventricular lead from the ipsilateral side of central vein obstruction
    Klaus K A Witte
    Division of Cardiology, University Health Network, University of Toronto, Canada
    J Interv Card Electrophysiol 13:47-50. 2005
  3. ncbi request reprint The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure
    Klaus K A Witte
    Department of Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham, Hull HU16 5JQ, UK
    Eur Heart J 26:2238-44. 2005
  4. ncbi request reprint Metabolic gas kinetics depend upon the level of exercise performed
    Klaus K A Witte
    Department of Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham, Hull HU16 5JQ, United Kingdom
    Eur J Heart Fail 7:991-6. 2005
  5. pmc Chronic heart failure, chronotropic incompetence, and the effects of beta blockade
    K K A Witte
    University of Hull, Hull, UK
    Heart 92:481-6. 2006
  6. ncbi request reprint Chronic heart failure and multiple micronutrient supplementation: realistic hope or idealistic conjecture?
    Klaus K A Witte
    Mount Sinai Hospital, University Health Network, Toronto, ON, Canada
    Heart Fail Monit 4:123-9. 2005
  7. pmc Excessive breathlessness in patients with diastolic heart failure
    K K A Witte
    Department of Academic Cardiology, Castle Hill Hospital, Kingston upon Hull, UK
    Heart 92:1425-9. 2006
  8. ncbi request reprint Biomechanical efficiency is impaired in patients with chronic heart failure
    Klaus K Witte
    Department of Cardiology, Leeds General Infirmary, Great George Street, Leeds, LS1 3EX, UK
    Eur J Heart Fail 9:834-8. 2007
  9. ncbi request reprint Micronutrients and their supplementation in chronic cardiac failure. An update beyond theoretical perspectives
    Klaus K Witte
    Mount Sinai Hospital, University Health Network, 600 University Avenue, Toronto, ON, M5J 1X5, Canada
    Heart Fail Rev 11:65-74. 2006
  10. ncbi request reprint Why does chronic heart failure cause breathlessness and fatigue?
    Klaus K Witte
    Academic Cardiology, Leeds General Infirmary, Great George Street, Leeds, UK
    Prog Cardiovasc Dis 49:366-84. 2007

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Marine polyunsaturated fatty acids in heart failure. Are the theoretical benefits matched by the clinical data?
    Klaus K A Witte
    Division of Cardiovascular and Diabetes Research, University of Leeds and Leeds General Infirmary, Leeds, United Kingdom
    Pol Arch Med Wewn 119:162-9. 2009
    ..The aim of this article is to review the theoretical benefits of marine PUFAs and to discuss the implications of the GISSI-HF study for the management of patients with CHF...
  2. ncbi request reprint Deployment of left ventricular lead from the ipsilateral side of central vein obstruction
    Klaus K A Witte
    Division of Cardiology, University Health Network, University of Toronto, Canada
    J Interv Card Electrophysiol 13:47-50. 2005
    ..We present a patient with central venous obstruction secondary to previously implanted defibrillator leads, in whom we achieved coronary sinus pacing through the ipsilateral internal jugular vein...
  3. ncbi request reprint The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure
    Klaus K A Witte
    Department of Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham, Hull HU16 5JQ, UK
    Eur Heart J 26:2238-44. 2005
    ..Therefore, we examined the influence of long-term multiple micronutrient supplementation on left ventricular (LV) function, levels of pro-inflammatory cytokines, and quality-of-life (QoL) in elderly patients with CHF...
  4. ncbi request reprint Metabolic gas kinetics depend upon the level of exercise performed
    Klaus K A Witte
    Department of Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham, Hull HU16 5JQ, United Kingdom
    Eur J Heart Fail 7:991-6. 2005
    ..The aim of the present study was to establish whether the kinetics of O2 are influenced by the work rate...
  5. pmc Chronic heart failure, chronotropic incompetence, and the effects of beta blockade
    K K A Witte
    University of Hull, Hull, UK
    Heart 92:481-6. 2006
    ..To establish the prevalence of chronotropic incompetence in a cohort of patients with chronic heart failure (CHF) taking modern medications for heart failure, and whether this affected exercise capacity and predicted prognosis...
  6. ncbi request reprint Chronic heart failure and multiple micronutrient supplementation: realistic hope or idealistic conjecture?
    Klaus K A Witte
    Mount Sinai Hospital, University Health Network, Toronto, ON, Canada
    Heart Fail Monit 4:123-9. 2005
    ..In this article, we review the effects of individual micronutrients and how they might impact on CHF, and present recent data that dietary supplementation might offer an addition to standard therapy for CHF...
  7. pmc Excessive breathlessness in patients with diastolic heart failure
    K K A Witte
    Department of Academic Cardiology, Castle Hill Hospital, Kingston upon Hull, UK
    Heart 92:1425-9. 2006
    ....
  8. ncbi request reprint Biomechanical efficiency is impaired in patients with chronic heart failure
    Klaus K Witte
    Department of Cardiology, Leeds General Infirmary, Great George Street, Leeds, LS1 3EX, UK
    Eur J Heart Fail 9:834-8. 2007
    ..This apparent increase in biomechanical efficiency (BE) might be due to a higher proportion of anaerobic metabolism which, although leading to lower VO2 during steady state exercise, must be compensated for during recovery...
  9. ncbi request reprint Micronutrients and their supplementation in chronic cardiac failure. An update beyond theoretical perspectives
    Klaus K Witte
    Mount Sinai Hospital, University Health Network, 600 University Avenue, Toronto, ON, M5J 1X5, Canada
    Heart Fail Rev 11:65-74. 2006
    ..The aim of this article is to briefly review the experimental rationale for each of the micronutrients of potential benefit in chronic heart failure and examine the current clinical trial evidence supporting their use...
  10. ncbi request reprint Why does chronic heart failure cause breathlessness and fatigue?
    Klaus K Witte
    Academic Cardiology, Leeds General Infirmary, Great George Street, Leeds, UK
    Prog Cardiovasc Dis 49:366-84. 2007
    ..In the present paper, we review the systemic consequences of left ventricular dysfunction to understand how they relate to the symptoms of heart failure...
  11. ncbi request reprint Fibrinogen synthesis is increased in cachectic patients with chronic heart failure
    Klaus K A Witte
    Department of Cardiology, Leeds General Infirmary, Great George Street, Leeds, LS1, UK
    Int J Cardiol 129:363-7. 2008
    ..We investigated the rate of hepatic fibrinogen synthesis by measuring the rate of incorporation of deuterated phenylalanine into circulating plasma fibrinogen...
  12. pmc Muscle sympathetic nerve activity and ventilation during exercise in subjects with and without chronic heart failure
    Klaus K A Witte
    University Health Network and Mount Sinai Hospital Division of Cardiology, University of Toronto, Ontario
    Can J Cardiol 24:275-8. 2008
    ..Previously, we demonstrated that peak oxygen uptake (pVO(2)) in HF relates inversely to MSNA at rest and during exercise...
  13. doi request reprint Implantable cardioverter-defibrillator therapy in adult patients with tetralogy of Fallot
    Klaus K Witte
    Department of Cardiology, University of Leeds and Leeds General Infirmary, Leeds, UK
    Europace 10:926-30. 2008
    ..ESC and AHA guidelines suggest the use of implantable cardioverter defibrillators (ICDs) to protect from this. Few data are available on the benefits of these devices in this population, and there are no randomized studies...
  14. pmc Carvedilol in the treatment of elderly patients with chronic heart failure
    Klaus K A Witte
    Academic Department of Cardiology, LIGHT Building, University of Leeds and Leeds General Infirmary, UK
    Clin Interv Aging 3:55-70. 2008
    ..The aim of the present article is to review the potential mechanisms of the benefits of adrenergic blockade in CHF and the clinical data available from the large randomized studies, focusing particularly on older patients...
  15. doi request reprint Chronotropic incompetence does not contribute to submaximal exercise limitation in patients with chronic heart failure
    Klaus K Witte
    Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, UK
    Int J Cardiol 134:342-4. 2009
    ....
  16. doi request reprint Dyspnoea versus fatigue: additional prognostic information from symptoms in chronic heart failure?
    Klaus K A Witte
    Division of Cardiovascular and Diabetes Research, LIGHT Building, LS1 3EX, United Kingdom
    Eur J Heart Fail 10:1224-8. 2008
    ..Patients with chronic heart failure (CHF) have exercise limitation due to breathlessness or fatigue, but it is unclear whether one symptom confers an adverse prognosis over the other...
  17. ncbi request reprint The effects of long-term beta-blockade on the ventilatory responses to exercise in chronic heart failure
    Klaus K A Witte
    Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham Hull HU16 5JQ, UK
    Eur J Heart Fail 7:612-7. 2005
    ..The aim of this study was to describe the effects of long-term beta-blocker therapy on metabolic gas exchange variables and ventilation during exercise in CHF patients...
  18. pmc Exercise capacity and cardiac function assessed by tissue Doppler imaging in chronic heart failure
    K K A Witte
    Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham, Hull HU16 5JQ, UK
    Heart 90:1144-50. 2004
    ..To examine the relation between longitudinal left ventricular function assessed by tissue Doppler imaging (TDi) and exercise capacity in heart failure...
  19. pmc Pattern of ventilation during exercise in chronic heart failure
    K K A Witte
    Academic Cardiology, Castle Hill Hospital, Cottingham, Hull HU16 5JQ, UK
    Heart 89:610-4. 2003
    ..To determine the pattern of the abnormal ventilatory response in heart failure and how it relates to symptoms by looking at tidal volume (VT) and frequency (f) during exercise...
  20. ncbi request reprint Nutritional abnormalities contributing to cachexia in chronic illness
    Klaus K A Witte
    Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham, HU16 5JQ, Hull, UK
    Int J Cardiol 85:23-31. 2002
    ....
  21. ncbi request reprint Is the elevated slope relating ventilation to carbon dioxide production in chronic heart failure a consequence of slow metabolic gas kinetics?
    Klaus K A Witte
    Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham, Hull HU16 5JQ, UK
    Eur J Heart Fail 4:469-72. 2002
    ..Patients with heart failure have slow metabolic gas exchange kinetics, which may contribute to the elevated slope of the relationship between ventilation and carbon dioxide production (Ve/Vco(2) slope)...
  22. pmc The effects of alpha and beta blockade on ventilatory responses to exercise in chronic heart failure
    K K A Witte
    Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham, Hull, UK
    Heart 89:1169-73. 2003
    ..To assess the influence of acute alpha and beta blockade on ventilation and symptoms of breathlessness during exercise in patients with chronic heart failure and in controls...
  23. ncbi request reprint Are hematinic deficiencies the cause of anemia in chronic heart failure?
    Klaus K A Witte
    Division of Academic Cardiology, Castle Hill Hospital, Cottingham, United Kingdom
    Am Heart J 147:924-30. 2004
    ..We explored the relation between hematinic levels and hemoglobin (Hb) levels and exercise tolerance in a group of patients with CHF...
  24. ncbi request reprint Chronic heart failure and micronutrients
    K K Witte
    Castle Hill Hospital, University of Hull, Kingston upon Hull, United Kingdom
    J Am Coll Cardiol 37:1765-74. 2001
    ..There is sufficient evidence to support a large-scale trial of dietary micronutrient supplementation in HF...
  25. doi request reprint Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failure
    Rhidian J Shelton
    Department of Academic Cardiology, Castle Hill Hospital, University of Hull, Kingston upon Hull, UK
    Eur J Heart Fail 12:983-9. 2010
    ..We aimed to determine the effect of submaximal exercise on CO and other haemodynamic variables in patients with CHF using a validated non-invasive inert gas rebreathing system...
  26. ncbi request reprint Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure
    Lee Ingle
    Carnegie Research Institute, Leeds Metropolitan University, Leeds, UK
    Eur J Heart Fail 10:85-8. 2008
    ..We wished to confirm whether combining these variables as a ratio would lead to a more accurate predictor of prognosis than using either alone...
  27. pmc A novel cardiopulmonary exercise test protocol and criterion to determine maximal oxygen uptake in chronic heart failure
    T Scott Bowen
    Institute of Membrane and Systems Biology, University of Leeds, Leeds, United Kingdom
    J Appl Physiol 113:451-8. 2012
    ..The RISE-95 test was well tolerated by CHF patients, supporting its use for Vo(2max) confirmation...
  28. ncbi request reprint Clinical trials update from the European Society of Cardiology meeting 2005: CARE-HF extension study, ESSENTIAL, CIBIS-III, S-ICD, ISSUE-2, STRIDE-2, SOFA, IMAGINE, PREAMI, SIRIUS-II and ACTIVE
    John G F Cleland
    Department of Cardiology, University of Hull, Castle Hill Hospital, Cottingham, Kingston upon Hull, UK
    Eur J Heart Fail 7:1070-5. 2005
    ..The ACTIVE W study of warfarin versus aspirin plus clopidogrel in atrial fibrillation has been stopped due to superiority of warfarin...
  29. doi request reprint Impact of different diagnostic criteria on the prevalence and prognostic significance of exertional oscillatory ventilation in patients with chronic heart failure
    Lee Ingle
    Carnegie Research Institute, Leeds Metropolitan University, Beckett s Park, Headingley, Leeds, UK
    Eur J Cardiovasc Prev Rehabil 16:451-6. 2009
    ..Two different definitions of EOV have been proposed by CorrĂ¡ and Leite. We aimed to compare the prevalence of EOV and its prognostic significance in patients with chronic heart failure using the two diagnostic approaches...
  30. doi request reprint Left ventricular strain patterns in dilated cardiomyopathy predict response to cardiac resynchronization therapy: timing is not everything
    Shemy Carasso
    University Health Network, University of Toronto, Toronto, Canada
    J Am Soc Echocardiogr 22:242-50. 2009
    ..The aim of this study was to develop prediction rules for successful CRT on the basis of mechanical strain patterns of left ventricular function rather than just the timing of activation...
  31. ncbi request reprint Clinical trials update from Heart Rhythm 2007 and Heart Failure 2007: CARISMA, PREPARE, DAVID II, SAVE-PACE, PROTECT and AREA-IN-CHF
    John G F Cleland
    Department of Cardiology, University of Hull, Castle Hill Hospital, Cottingham, Kingston upon Hull, HU16 5JQ, UK
    Eur J Heart Fail 9:850-3. 2007
    ..AREA-IN-CHF failed to show a beneficial effect of canrenone on LV volumes compared to placebo however some beneficial effects on secondary clinical endpoints were observed...
  32. ncbi request reprint The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of <1.0 in patients with chronic heart failure
    Lee Ingle
    Carnegie Research Institute, Leeds Metropolitan University, Beckett s Park, Headingley, Leeds, LS6 3QS, United Kingdom
    Int J Cardiol 127:88-92. 2008
    ..The aim of the current study was to compare the prognostic value of CPETs with a peak respiratory exchange ratio (pRER)<1.0 versus a pRER>/=1.0 in a large, representative sample of patients with CHF...
  33. ncbi request reprint Airway resistance in chronic heart failure measured by impulse oscillometry
    Klaus K A Witte
    Department of Academic Cardiology, Castle Hill Hospital, Cottingham, Hull, UK
    J Card Fail 8:225-31. 2002
    ..Increased airway resistance by increasing the work of breathing might contribute to exercise intolerance in CHF...
  34. ncbi request reprint Beta-blockers and inspiratory pulmonary function in chronic heart failure
    Klaus K A Witte
    Academic Cardiology, Castle Hill Hospital, Cottingham, Hull, England
    J Card Fail 11:112-6. 2005
    ..Beta-blockers cause fatigue but have become part of the standard management of CHF. We explored the relation between respiratory muscle power in CHF and the effects of long-term beta-blockade...
  35. pmc The intramuscular contribution to the slow oxygen uptake kinetics during exercise in chronic heart failure is related to the severity of the condition
    T Scott Bowen
    Institute of Membrane and Systems Biology, University of Leeds, Leeds, UK
    J Appl Physiol 112:378-87. 2012
    ..The most severely limited patients, however, appear to have an intramuscular pathology that limits Vo(2) kinetics during moderate exercise...
  36. doi request reprint Cardiac sympathetic activation in patients with pulmonary arterial hypertension
    Susanna Mak
    Division of Cardiology, Department of Medicine, Mount Sinai Hospital, University Health Network, Toronto, Canada
    Am J Physiol Regul Integr Comp Physiol 302:R1153-7. 2012
    ..Therefore, cardiac sympathetic activation occurs in PAH. The mechanism of this activation remains uncertain but does not involve elevations in left heart filling pressure...
  37. ncbi request reprint Left ventricular morphology, global and longitudinal function in normal older individuals: a cardiac magnetic resonance study
    Nikolay P Nikitin
    Academic Department of Cardiology, The University of Hull, Castle Hill Hospital, Castle Road, Cottingham, Kingston upon Hull, HU16 5JQ United Kingdom
    Int J Cardiol 108:76-83. 2006
    ..This study was designed to assess left ventricular (LV) morphology, global and longitudinal function in healthy older men and women using cardiac magnetic resonance (CMR)...
  38. ncbi request reprint The effect of aspirin on the ventilatory response to exercise in chronic heart failure
    Klaus K A Witte
    Department of Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham Hull, HU16 5JQ, UK
    Eur J Heart Fail 6:745-8. 2004
    ..The present study examined the influence of the presence of a potent non-selective prostaglandin inhibitor, aspirin, on the ventilatory response to exercise in a group of patients with CHF...
  39. ncbi request reprint The effect of ventricular pacing on measurements of left ventricular function: a comparison between echocardiographic methods and with radionuclide ventriculography
    Simon D R Thackray
    Department of Academic Cardiology, University of Hull, Castle Hill Hospital, Cottingham, East Yorkshire, UK
    Eur J Echocardiogr 7:284-92. 2006
    ..Different methods exist for measuring left ventricular function echocardiographically; each may be error prone due to the abnormal pattern of ventricular activation during pacing...
  40. ncbi request reprint The prevalence of heart failure and asymptomatic left ventricular systolic dysfunction in a typical regional pacemaker population
    Simon D R Thackray
    Castle Hill Hospital, University of Hull, Cottingham, Hull, UK
    Eur Heart J 24:1143-52. 2003
    ..To assess the prevalence of heart failure and asymptomatic left ventricular systolic dysfunction in the chronically paced population...
  41. ncbi request reprint Fish oils--adjuvant therapy in chronic heart failure?
    Klaus K A Witte
    Castle Hill Hospital, Castle Road, Cottingham, Hull, UK
    Eur J Cardiovasc Prev Rehabil 11:267-74. 2004
    ..In this review article we discuss the potential benefits of PUFA supplementation in CHF patients using data from clinical trials and in vitro experiments...
  42. ncbi request reprint The reversibility of increased airways resistance in chronic heart failure measured by impulse oscillometry
    Klaus K A Witte
    Department of Academic Cardiology, Castle Hill Hospital, Cottingham, Hull, United Kingdom
    J Card Fail 10:149-54. 2004
    ..The aim of this study was to determine whether the pulmonary abnormalities are reversible and whether any improvements lead to changes to exercise capacity or symptoms...
  43. ncbi request reprint Longitudinal ventricular function: normal values of atrioventricular annular and myocardial velocities measured with quantitative two-dimensional color Doppler tissue imaging
    Nikolay P Nikitin
    Department of Cardiology, University of Hull School of Medicine, Cottingham, Kingston upon Hull, United Kingdom
    J Am Soc Echocardiogr 16:906-21. 2003
    ..The aim of this study was to obtain normal values for atrioventricular annular and regional myocardial velocities using this method...
  44. ncbi request reprint The effect of altering heart rate on ventricular function in patients with heart failure treated with beta-blockers
    Simon D R Thackray
    Department of Academic Cardiology, University of Hull, Castle Hill Hospital, Kingston upon Hull, United Kingdom
    Am Heart J 152:713.e9-13. 2006
    ..Beta-blockers are effective for the treatment of heart failure, but their mechanism of action is unresolved. Heart rate reduction may be a central mechanism or a troublesome side effect...
  45. ncbi request reprint Identification of lateral cardiac veins for cardiac resynchronization therapy
    Klaus K Witte
    Division of Cardiology, University Health Network, University of Toronto, Mount Sinai Hospital, Room 1609, 600 University Avenue, Toronto, Ont, Canada, M5G 1X5
    Europace 8:506-7. 2006
  46. pmc Biventricular pacing: impact on exercise-induced increases in mitral insufficiency in patients with chronic heart failure
    Klaus K Witte
    Department of Medicine, Mount Sinai and University Health Network Hospitals, University of Toronto, Toronto, Ontario
    Can J Cardiol 24:379-84. 2008
    ..Cardiac resynchronization therapy (CRT) reduces MR at rest, but its effects on exercise-induced worsening of MR are incompletely explored. The present study examined the influence of CRT on MR during submaximal exercise in CHF patients...
  47. ncbi request reprint Incidence of renal dysfunction over 6 months in patients with chronic heart failure due to left ventricular systolic dysfunction: contributing factors and relationship to prognosis
    Ramesh de Silva
    Academic Department of Cardiology, Castle Hill Hospital, University of Hull, Castle Road, Cottingham, Hull HU16 5JQ, UK
    Eur Heart J 27:569-81. 2006
    ....
  48. ncbi request reprint Effects of applying a standardised management algorithm for moderate to severe renal dysfunction in patients with chronic stable heart failure
    Ramesh de Silva
    Department of Cardiology, University of Hull, Castle Hill Hospital, Kingston upon Hull, East Yorkshire, HU16 5JQ, United Kingdom
    Eur J Heart Fail 9:415-23. 2007
    ..No specific guidelines exist on how to manage renal dysfunction (RD) in patients with chronic heart failure (CHF)...
  49. ncbi request reprint Biventricular pacemaker upgrade in previously paced heart failure patients--improvements in ventricular dyssynchrony
    Klaus K A Witte
    Division of Cardiology, University Health Network, University of Toronto, Canada
    J Card Fail 12:199-204. 2006
    ..There are few data demonstrating the effects of CRT on contemporary dyssynchrony variables in patients with advanced heart failure who have been chronically paced from the right ventricle (RV)...
  50. doi request reprint Diabetes mellitus is associated with adverse prognosis in chronic heart failure of ischaemic and non-ischaemic aetiology
    Richard M Cubbon
    Multidisciplinary Cardiovascular Research Centre, The University of Leeds, Leeds, UK
    Diab Vasc Dis Res 10:330-6. 2013
    ..It is unclear whether diabetes mellitus (DM) is an adverse prognostic factor in chronic heart failure (CHF) of ischaemic and non-ischaemic aetiology managed with contemporary evidence-based care...
  51. ncbi request reprint Epidemiology, associated factors, and prognostic outcomes of renal artery stenosis in chronic heart failure assessed by magnetic resonance angiography
    Ramesh de Silva
    Academic Cardiology, University of Hull, Castle Hill Hospital, Cottingham, East Yorkshire, United Kingdom
    Am J Cardiol 100:273-9. 2007
    ..Interventional trials on renal revascularization are underway that contain subsets of patients with HF that may provide evidence on how best to manage RAS in this setting...
  52. ncbi request reprint Anemia, renal dysfunction, and their interaction in patients with chronic heart failure
    Ramesh de Silva
    Academic Cardiology, University of Hull, Castle Hill Hospital, Cottingham, United Kingdom
    Am J Cardiol 98:391-8. 2006
    ..In conclusion, in outpatients with chronic HF, anemia and RD are common and co-exist but confer independent prognostic information. A deficiency of conventional hematinic factors may cause about 1/3 of anemia in this clinical setting...
  53. doi request reprint Chronotropic incompetence and survival in chronic heart failure
    Yahya Al-Najjar
    Dept of Cardiology, Hull York Medical School, UK
    Int J Cardiol 157:48-52. 2012
    ..It is common in patients with chronic heart failure (CHF), and we wanted to explore the relation between CI and outcome in unselected patients with CHF...
  54. doi request reprint Changing characteristics and mode of death associated with chronic heart failure caused by left ventricular systolic dysfunction: a study across therapeutic eras
    Richard M Cubbon
    University of Leeds, Leeds, United Kingdom
    Circ Heart Fail 4:396-403. 2011
    ..The cumulative effect of these therapies on mortality, mode of death, symptoms, and clinical characteristics has yet to be defined...
  55. ncbi request reprint Color tissue Doppler-derived long-axis left ventricular function in heart failure with preserved global systolic function
    Nikolay P Nikitin
    Department of Cardiology, Academic Unit, University of Hull School of Medicine, Castle Hill Hospital, Kingston upon Hull HU16 5JQ, UK
    Am J Cardiol 90:1174-7. 2002
  56. ncbi request reprint Application of tissue Doppler imaging in cardiology
    Nikolay P Nikitin
    Department of Cardiology, Academic Unit, University of Hull School of Medicine, Kingston upon Hull, UK
    Cardiology 101:170-84. 2004
    ..Right ventricular function, intracardiac and pulmonary artery pressures, transplant rejection and intraventricular dyssynchrony can also be assessed. This article reviews the current and evolving applications of TDI in cardiology...
  57. ncbi request reprint Longitudinal myocardial dysfunction in healthy older subjects as a manifestation of cardiac ageing
    Nikolay P Nikitin
    The University of Hull, Academic Department of Cardiology, Castle Hill Hospital, Kingston upon Hull HU16 5JQ, UK
    Age Ageing 34:343-9. 2005
    ..Abnormalities of longitudinal left ventricular (LV) contraction and relaxation may be early markers of cardiac disease. This study was designed to assess the relationship between long-axis LV function and age in healthy subjects...
  58. ncbi request reprint The recognition and treatment of pericarditis
    Klaus K A Witte
    University of Hull
    Practitioner 246:429-31, 434-5. 2002