Miranka Wirth

Summary

Publications

  1. pmc Gene-Environment Interactions: Lifetime Cognitive Activity, APOE Genotype, and Beta-Amyloid Burden
    Miranka Wirth
    Helen Wills Neuroscience Institute and
    J Neurosci 34:8612-7. 2014
  2. pmc Neuroprotective pathways: lifestyle activity, brain pathology, and cognition in cognitively normal older adults
    Miranka Wirth
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA Electronic address
    Neurobiol Aging 35:1873-82. 2014
  3. pmc The effect of amyloid β on cognitive decline is modulated by neural integrity in cognitively normal elderly
    Miranka Wirth
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA Electronic address
    Alzheimers Dement 9:687-698.e1. 2013
  4. pmc Alzheimer's disease neurodegenerative biomarkers are associated with decreased cognitive function but not β-amyloid in cognitively normal older individuals
    Miranka Wirth
    Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California 94720, USA
    J Neurosci 33:5553-63. 2013
  5. doi request reprint Effects of transcranial direct current stimulation (tDCS) on behaviour and electrophysiology of language production
    Miranka Wirth
    University Hospital of Psychiatry, Department of Psychiatric Neurophysiology, Bern, Switzerland
    Neuropsychologia 49:3989-98. 2011
  6. doi request reprint Associations between Alzheimer disease biomarkers, neurodegeneration, and cognition in cognitively normal older people
    Miranka Wirth
    Helen Wills Neuroscience Institute, University of California, Berkeley
    JAMA Neurol 70:1512-9. 2013
  7. doi request reprint Gray matter volume differences specific to formal thought disorder in schizophrenia
    Helge Horn
    University Hospital of Psychiatry, University of Bern, Murtenstrasse 21, Bern, Switzerland
    Psychiatry Res 182:183-6. 2010
  8. doi request reprint Structural plasticity in the language system related to increased second language proficiency
    Maria Stein
    University Hospital of Psychiatry, Department of Psychiatric Neurophysiology, Bern, Switzerland
    Cortex 48:458-65. 2012
  9. ncbi request reprint Correlation between topographic N400 anomalies and reduced cerebral blood flow in the anterior temporal lobes of patients with dementia
    Matthias Grieder
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bolligenstrasse 111, Bern, Switzerland
    J Alzheimers Dis 36:711-31. 2013
  10. doi request reprint Performance during face processing differentiates schizophrenia patients with delusional misidentifications
    Sebastian Walther
    University Hospital of Psychiatry, University of Bern, Bern, Switzerland
    Psychopathology 43:127-36. 2010

Collaborators

Detail Information

Publications19

  1. pmc Gene-Environment Interactions: Lifetime Cognitive Activity, APOE Genotype, and Beta-Amyloid Burden
    Miranka Wirth
    Helen Wills Neuroscience Institute and
    J Neurosci 34:8612-7. 2014
    ..The effect could imply that cognitive training promotes increased neural efficiency that might retard the lifelong neurally mediated deposition of Aβ. ..
  2. pmc Neuroprotective pathways: lifestyle activity, brain pathology, and cognition in cognitively normal older adults
    Miranka Wirth
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA Electronic address
    Neurobiol Aging 35:1873-82. 2014
    ..Lifestyle activity may thus promote cognitive health in aging by protecting against cerebrovascular pathology and Aβ pathology thought to be relevant to AD development. ..
  3. pmc The effect of amyloid β on cognitive decline is modulated by neural integrity in cognitively normal elderly
    Miranka Wirth
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA Electronic address
    Alzheimers Dement 9:687-698.e1. 2013
    ..The objective of this study was to relate AD-sensitive biomarkers of Aβ and neurodegeneration and their interaction to longitudinal cognitive change in cognitively normal elderly...
  4. pmc Alzheimer's disease neurodegenerative biomarkers are associated with decreased cognitive function but not β-amyloid in cognitively normal older individuals
    Miranka Wirth
    Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California 94720, USA
    J Neurosci 33:5553-63. 2013
    ..The impact of neural integrity on cognitive functions is, however, enhanced in the presence of high Aβ burden for brain regions that are most affected in AD...
  5. doi request reprint Effects of transcranial direct current stimulation (tDCS) on behaviour and electrophysiology of language production
    Miranka Wirth
    University Hospital of Psychiatry, Department of Psychiatric Neurophysiology, Bern, Switzerland
    Neuropsychologia 49:3989-98. 2011
    ..The present functional and oscillatory neural markers could detect positive effects of prefrontal A-tDCS, which could be of use in the neuro-rehabilitation of frontal language functions...
  6. doi request reprint Associations between Alzheimer disease biomarkers, neurodegeneration, and cognition in cognitively normal older people
    Miranka Wirth
    Helen Wills Neuroscience Institute, University of California, Berkeley
    JAMA Neurol 70:1512-9. 2013
    ..The study quantified neurodegenerative abnormalities using imaging biomarkers and examined cross-sectional relationships with Aβ deposition; white matter lesions (WMLs), a marker of cerebrovascular disease; and cognitive functions...
  7. doi request reprint Gray matter volume differences specific to formal thought disorder in schizophrenia
    Helge Horn
    University Hospital of Psychiatry, University of Bern, Murtenstrasse 21, Bern, Switzerland
    Psychiatry Res 182:183-6. 2010
    ..The specific GM abnormalities within the left temporal lobe may help to explain language disturbances included in FTD...
  8. doi request reprint Structural plasticity in the language system related to increased second language proficiency
    Maria Stein
    University Hospital of Psychiatry, Department of Psychiatric Neurophysiology, Bern, Switzerland
    Cortex 48:458-65. 2012
    ..This indicates that the individual amount of learning is reflected in brain structure changes, regardless of absolute proficiency...
  9. ncbi request reprint Correlation between topographic N400 anomalies and reduced cerebral blood flow in the anterior temporal lobes of patients with dementia
    Matthias Grieder
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bolligenstrasse 111, Bern, Switzerland
    J Alzheimers Dis 36:711-31. 2013
    ....
  10. doi request reprint Performance during face processing differentiates schizophrenia patients with delusional misidentifications
    Sebastian Walther
    University Hospital of Psychiatry, University of Bern, Bern, Switzerland
    Psychopathology 43:127-36. 2010
    ..Two antagonistic forms of DMS are the hypoidentification (Capgras) and hyperidentification (Fregoli) syndromes. We aimed to highlight differences between these subtypes using a face recognition memory task...
  11. doi request reprint Electrophysiological and behavioral correlates of stable automatic semantic retrieval in aging
    Matthias Grieder
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern, Bern, Switzerland
    Neuropsychologia 50:160-71. 2012
    ..The present results add new behavioral and neurophysiological evidence to earlier findings, by showing that automatic semantic retrieval remains stable in global signal strength and topographic distribution during healthy aging...
  12. doi request reprint Reduced frontal activation with increasing 2nd language proficiency
    Maria Stein
    University Hospital of Psychiatry, Department of Psychiatric Neurophysiology, Bolligenstrasse 111, CH 3000 Bern 60, Switzerland
    Neuropsychologia 47:2712-20. 2009
    ..Our results demonstrate that lexico-semantic processing of first and second language converges onto similar networks as second language proficiency increases...
  13. doi request reprint The early context effect reflects activity in the temporo-prefrontal semantic system: evidence from electrical neuroimaging of abstract and concrete word reading
    Miranka Wirth
    University Hospital of Psychiatry, Bern, Switzerland
    Neuroimage 42:423-36. 2008
    ..Taken together our findings show that the early context effect reflects activation processes in verbal semantic memory...
  14. doi request reprint Semantic memory involvement in the default mode network: a functional neuroimaging study using independent component analysis
    Miranka Wirth
    University Hospital of Psychiatry, Department of Psychiatric Neurophysiology, Bern, Switzerland
    Neuroimage 54:3057-66. 2011
    ..The present study further supports the hypothesis of the DMN as an internal mentation system that involves declarative memory functions...
  15. doi request reprint Structural and metabolic changes in language areas linked to formal thought disorder
    Helge Horn
    University Hospital of Psychiatry, Bolligenstrasse 111, CH 3000, Bern 60, Switzerland
    Br J Psychiatry 194:130-8. 2009
    ..The role of the language network in the pathophysiology of formal thought disorder has yet to be elucidated...
  16. pmc Cortical thickness mediates the effect of β-amyloid on episodic memory
    Sylvia Villeneuve
    From the Helen Wills Neuroscience Institute S V, M W, C M M, N A, W J J, University of California, Berkeley Department of Neurology B R R, D M, C D, University of California, Davis School of Education and Social Policy C M H, Northwestern University Departments of Preventive Medicine W M and Neurology H C C, University of Southern California Center for Imaging of Neurodegenerative Diseases M W W, University of California, San Francisco
    Neurology 82:761-7. 2014
    ..To investigate the associations among β-amyloid (Aβ), cortical thickness, and episodic memory in a cohort of cognitively normal to mildly impaired individuals at increased risk of vascular disease...
  17. doi request reprint Theta burst TMS increases cerebral blood flow in the primary motor cortex during motor performance as assessed by arterial spin labeling (ASL)
    Ariane Orosz
    Department of Psychiatric Neurophysiology, University Hospital of Psychiatry Bern, Switzerland
    Neuroimage 61:599-605. 2012
    ..This compensatory reaction seems to be observable at the metabolic, but not at the behavioral level...
  18. doi request reprint Encoding deficit during face processing within the right fusiform face area in schizophrenia
    Sebastian Walther
    University Hospital of Psychiatry, University of Bern, Bolligenstrasse 111, 3000 Bern 60, Switzerland
    Psychiatry Res 172:184-91. 2009
    ..Our results support the hypothesis that impaired face processing in schizophrenia is related to early-stage deficits during the encoding and recognition of faces...
  19. pmc Is verbal episodic memory in elderly with amyloid deposits preserved through altered neuronal function?
    Rik Ossenkoppele
    Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA Department of Nuclear Medicine and PET Research, VU University Medical Center, Amsterdam, the Netherlands Department of Neurology and Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands
    Cereb Cortex 24:2210-8. 2014
    ..This preliminary study suggests that neural compensation, as a manifestation of brain reserve, enables elderly supposedly on the path to AD, at least temporarily, to preserve cognitive function. ..