Martin Wilson

Summary

Publications

  1. ncbi request reprint A constrained least-squares approach to the automated quantitation of in vivo ¹H magnetic resonance spectroscopy data
    Martin Wilson
    Cancer Sciences, University of Birmingham, Birmingham, United Kingdom
    Magn Reson Med 65:1-12. 2011
  2. ncbi request reprint Noninvasive detection of glutamate predicts survival in pediatric medulloblastoma
    Martin Wilson
    School of Cancer Sciences, University of Birmingham, Birmingham Birmingham Children s Hospital NHS Foundation Trust, Birmingham and
    Clin Cancer Res 20:4532-9. 2014
  3. pmc Magnetic resonance spectroscopy metabolite profiles predict survival in paediatric brain tumours
    Martin Wilson
    School of Cancer Sciences, University of Birmingham, Birmingham, UK
    Eur J Cancer 49:457-64. 2013
  4. pmc Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers
    Alan J Wright
    Cardiac and Vascular Sciences, St George s, University of London, London, UK
    Mol Cancer 9:66. 2010
  5. ncbi request reprint A quantitative comparison of metabolite signals as detected by in vivo MRS with ex vivo 1H HR-MAS for childhood brain tumours
    Martin Wilson
    Academic Department of Paediatrics and Child Health, University of Birmingham, UK
    NMR Biomed 22:213-9. 2009
  6. pmc High resolution magic angle spinning 1H NMR of childhood brain and nervous system tumours
    Martin Wilson
    Cancer Sciences, University of Birmingham, Birmingham, UK
    Mol Cancer 8:6. 2009
  7. ncbi request reprint Lipid biomarkers of glioma cell growth arrest and cell death detected by 1 H magic angle spinning MRS
    Ladan Mirbahai
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    NMR Biomed 25:1253-62. 2012
  8. ncbi request reprint The size of cytoplasmic lipid droplets varies between tumour cell lines of the nervous system: a 1H NMR spectroscopy study
    Xiaoyan Pan
    Cancer Sciences, University of Birmingham, Birmingham, UK
    MAGMA 25:479-85. 2012
  9. ncbi request reprint In vitro metabonomic study detects increases in UDP-GlcNAc and UDP-GalNAc, as early phase markers of cisplatin treatment response in brain tumor cells
    Xiaoyan Pan
    Cancer Sciences, University of Birmingham, Birmingham, United Kingdom
    J Proteome Res 10:3493-500. 2011
  10. ncbi request reprint The lipid composition of isolated cytoplasmic lipid droplets from a human cancer cell line, BE(2)M17
    Xiaoyan Pan
    Cancer Sciences, Institute of Child Health, University of Birmingham, Birmingham, UK
    Mol Biosyst 8:1694-700. 2012

Collaborators

Detail Information

Publications18

  1. ncbi request reprint A constrained least-squares approach to the automated quantitation of in vivo ¹H magnetic resonance spectroscopy data
    Martin Wilson
    Cancer Sciences, University of Birmingham, Birmingham, United Kingdom
    Magn Reson Med 65:1-12. 2011
    ..In conclusion, TARQUIN has been shown to be an accurate and robust algorithm for the analysis of magnetic resonance spectroscopy data making it suitable for use in a clinical setting...
  2. ncbi request reprint Noninvasive detection of glutamate predicts survival in pediatric medulloblastoma
    Martin Wilson
    School of Cancer Sciences, University of Birmingham, Birmingham Birmingham Children s Hospital NHS Foundation Trust, Birmingham and
    Clin Cancer Res 20:4532-9. 2014
    ..In this study, 1H magnetic resonance spectroscopy (MRS) was used to investigate noninvasive molecular biomarkers of survival in medulloblastoma...
  3. pmc Magnetic resonance spectroscopy metabolite profiles predict survival in paediatric brain tumours
    Martin Wilson
    School of Cancer Sciences, University of Birmingham, Birmingham, UK
    Eur J Cancer 49:457-64. 2013
    ..The primary aim of this study was to investigate whether MRS detectable molecules can predict the survival of paediatric brain tumour patients...
  4. pmc Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers
    Alan J Wright
    Cardiac and Vascular Sciences, St George s, University of London, London, UK
    Mol Cancer 9:66. 2010
    ..Accurate biochemical assignment of small molecule metabolites that are "NMR visible" will improve our interpretation of HRMAS data and the translation of NMR tumour biomarkers to in-vivo studies...
  5. ncbi request reprint A quantitative comparison of metabolite signals as detected by in vivo MRS with ex vivo 1H HR-MAS for childhood brain tumours
    Martin Wilson
    Academic Department of Paediatrics and Child Health, University of Birmingham, UK
    NMR Biomed 22:213-9. 2009
    ..HR-MAS can be used to improve the analysis and understanding of MRS data...
  6. pmc High resolution magic angle spinning 1H NMR of childhood brain and nervous system tumours
    Martin Wilson
    Cancer Sciences, University of Birmingham, Birmingham, UK
    Mol Cancer 8:6. 2009
    ..1H magic angle spinning NMR spectroscopy (1H HR-MAS) is a powerful tool for determining metabolite profiles from small pieces of intact tissue and could potentially provide important molecular information...
  7. ncbi request reprint Lipid biomarkers of glioma cell growth arrest and cell death detected by 1 H magic angle spinning MRS
    Ladan Mirbahai
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    NMR Biomed 25:1253-62. 2012
    ..1) H MRS can detect lipid alterations during cell cycle arrest and progression of cell death, and has the potential to provide a noninvasive biomarker of treatment efficacy in vivo...
  8. ncbi request reprint The size of cytoplasmic lipid droplets varies between tumour cell lines of the nervous system: a 1H NMR spectroscopy study
    Xiaoyan Pan
    Cancer Sciences, University of Birmingham, Birmingham, UK
    MAGMA 25:479-85. 2012
    ..1)H Nuclear Magnetic Resonance (NMR) spectroscopy detects resonances from lipids present in cytoplasmic (LDs); an understanding of the relationship between LD characteristics and NMR lipid signals is important...
  9. ncbi request reprint In vitro metabonomic study detects increases in UDP-GlcNAc and UDP-GalNAc, as early phase markers of cisplatin treatment response in brain tumor cells
    Xiaoyan Pan
    Cancer Sciences, University of Birmingham, Birmingham, United Kingdom
    J Proteome Res 10:3493-500. 2011
    ..However, the present study mechanistically links UDP-GlcNAc and UDP-GalNAc to cancer cell death following chemotherapeutic treatment...
  10. ncbi request reprint The lipid composition of isolated cytoplasmic lipid droplets from a human cancer cell line, BE(2)M17
    Xiaoyan Pan
    Cancer Sciences, Institute of Child Health, University of Birmingham, Birmingham, UK
    Mol Biosyst 8:1694-700. 2012
    ..LDs contain a specific group of lipid species that are likely to contribute to the (1)H NMR spectrum of cells...
  11. ncbi request reprint A comparison between simulated and experimental basis sets for assessing short-TE in vivo ¹H MRS data at 1.5 T
    Martin Wilson
    Cancer Sciences, University of Birmingham, UK
    NMR Biomed 23:1117-26. 2010
    ..Multiple analyses using slightly modified basis sets may be useful in estimating fitting errors, which are not predicted by CRLBs...
  12. ncbi request reprint A hybrid method of application of independent component analysis to in vivo 1H MR spectra of childhood brain tumours
    Jie Hao
    Biomedical Informatics, Signals and Systems Research Laboratory, School of Electronic, Electrical and Computer Engineering, University of Birmingham, Birmingham, UK
    NMR Biomed 25:594-606. 2012
    ..Furthermore, we were able to automatically extract metabolites from the patient MR spectra dataset that were not in commonly used basis sets (e.g. guanidinoacetate)...
  13. ncbi request reprint An algorithm for the automated quantitation of metabolites in in vitro NMR signals
    Greg Reynolds
    Department of Electronic, Electrical, and Computer Engineering, University of Birmingham, UK
    Magn Reson Med 56:1211-9. 2006
    ..Simulation was used to investigate the biggest peak shifts that can be tolerated...
  14. ncbi request reprint 1H magnetic resonance spectroscopy metabolites as biomarkers for cell cycle arrest and cell death in rat glioma cells
    Ladan Mirbahai
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    Int J Biochem Cell Biol 43:990-1001. 2011
    ..Understanding (1)H MRS changes occurring in cells during cell stress and cell death in vitro should aid the selection of pertinent biomarkers for clinical use...
  15. pmc Clinical protocols for ³¹P MRS of the brain and their use in evaluating optic pathway gliomas in children
    Jan Novak
    School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom Birmingham Children s Hospital, Birmingham, United Kingdom Electronic address
    Eur J Radiol 83:e106-12. 2014
    ..We demonstrate (31)P MRS can provide robust metabolic information on an acceptable timescale to yield information of clinical importance...
  16. pmc MR spectroscopy-based brain metabolite profiling in propionic acidaemia: metabolic changes in the basal ganglia during acute decompensation and effect of liver transplantation
    James E Davison
    Birmingham Children s Hospital NHS Foundation Trust, Birmingham, UK
    Orphanet J Rare Dis 6:19. 2011
    ..The present study utilises quantitative magnetic resonance spectroscopy (MRS) to investigate brain metabolite alterations in propionic acidaemia during metabolic stability and acute encephalopathic episodes...
  17. ncbi request reprint 1H MRS identifies specific metabolite profiles associated with MYCN-amplified and non-amplified tumour subtypes of neuroblastoma cell lines
    Andrew C Peet
    Department of Academic Paediatrics and Child Health, University of Birmingham, Whittall Street, Birmingham B4 6NH, UK
    NMR Biomed 20:692-700. 2007
    ..Molecular pathways of choline and taurine metabolism are potential targets for new agents tailored to MYCN-amplified neuroblastoma...
  18. ncbi request reprint MRS water resonance frequency in childhood brain tumours: a novel potential biomarker of temperature and tumour environment
    Ben Babourina-Brooks
    School of Cancer Sciences, University of Birmingham, Birmingham, West Midlands, UK Children s Hospital NHS Foundation Trust, Birmingham, West Midlands, UK
    NMR Biomed 27:1222-9. 2014
    ..This study has shown that the water PRF value has the potential to be used for characterizing childhood brain tumours, which has not been reported previously...