Reduced myocardial cellular damage and lipid peroxidation in off-pump versus conventional coronary artery bypass graftingS M Wildhirt
Department of Cardiac Surgery, Ludwig Maximilians University, Marchioninistr 15, D 81377 Munich, Germany uni muenchen de
Eur J Med Res 5:222-8. 2000
..This study tested whether OPCAB reduces myocardial cell damage, lipid peroxidation and systemic endothelin release when compared to conventional coronary artery bypass grafting...
S-methylisothiourea inhibits inducible nitric oxide synthase and improves left ventricular performance after acute myocardial infarctionS M Wildhirt
Department of Cardiac Surgery, Ludwig Maximilians University, Munich, Germany
Biochem Biophys Res Commun 227:328-33. 1996
..Induction of myocardial iNOS after MI on POD 3 contributes to the development of left ventricular dysfunction; modulation of iNOS activity by SMT improves left ventricular performance and may be beneficial after acute MI...
An association between microvascular endothelial dysfunction, transcardiac nitric oxide production and pro-inflammatory cytokines after heart transplantation in humansS M Wildhirt
Department of Cardiac Surgery, Grosshadern Hospital, Ludwig Maximilians University, Munich, Germany
Transpl Int 13:S228-34. 2000
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Inducible nitric oxide synthase activation after ischemia/reperfusion contributes to myocardial dysfunction and extent of infarct size in rabbits: evidence for a late phase of nitric oxide-mediated reperfusion injuryS M Wildhirt
Department of Cardiac Surgery, Ludwig Maximilians University, Munich, Germany
Cardiovasc Res 43:698-711. 1999
..The present study investigated the effects of selective and continuous inhibition of iNOS on myocardial performance, infarct size and histomorphological changes after I/R in rabbits...
Effects of Celsior and University of Wisconsin preservation solutions on hemodynamics and endothelial function after cardiac transplantation in humans: a single-center, prospective, randomized trialS M Wildhirt
Department of Cardiac Surgery, Grosshadern Hospital, Ludwig Maximilians University, Munich, Germany
Transpl Int 13:S203-11. 2000
..The positive correlation between impaired endothelial function and total ischemic time in the Celsior group requires longitudinal investigation in particular with regard to the development of allograft vasculopathy...
Selective modulation of inducible nitric oxide synthase isozyme in myocardial infarctionS M Wildhirt
Department of Cardiac Surgery, Ludwig Maximilians University, Munich, Germany
Circulation 96:1616-23. 1997
..We investigated the contribution of increased iNOS activity to the development of left ventricular dysfunction after myocardial infarction by selective inhibition of the isozyme...
Aminoguanidine inhibits inducible NOS and reverses cardiac dysfunction late after ischemia and reperfusion--implications for iNOS-mediated myocardial stunningS M Wildhirt
Department of Cardiac Surgery, Ludwig Maximilians University, Munich, Germany
Thorac Cardiovasc Surg 47:137-43. 1999
..The functional significance of inducible nitric oxide synthase (iNOS) activation in response to myocardial ischemia and reperfusion (I/R) was investigated...
Continuous transesophageal echocardiographic (TEE) monitoring during port-access cardiac surgeryC J Schulze
Department of Cardiac Surgery, University Hospital Grosshadern, Ludwig Maximilians University, Marchionistr 15, D 81337 Munich, Germany
Heart Surg Forum 2:54-9. 1999
..We investigated whether or not single TEE is feasible for perioperative monitoring of the placement, localization and proper function of the endovascular cardiopulmonary bypass (CPB) devices...
Coronary flow reserve and nitric oxide synthases after cardiac transplantation in humansS M Wildhirt
Department of Cardiac Surgery, Ludwig Maximilians University, Munich, Germany
Eur J Cardiothorac Surg 19:840-7. 2001
..We therefore investigated the potential relationship between the expression of nitric oxide synthases (NOS) and coronary endothelial function in human cardiac transplant recipients over time...