Multidimensional health status of HIV-infected outpatients at a tertiary care center in north IndiaNaveet Wig
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Indian J Med Sci 62:87-97. 2008
..However, in clinical settings, there is a felt need of description of problems commonly perceived by patients...
Dietary adequacy in Asian Indians with HIVN Wig
Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India
AIDS Care 20:370-5. 2008
..Dietary intake of many food constituents is significantly less in HIV patients than that recommended. Dietary counselling and efforts to improve food security are important in management of these patients...
- The impact of HIV/AIDS on the quality of life: a cross sectional study in north India
Naveet Wig
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Indian J Med Sci 60:3-12. 2006
..To determine the impact of Human Deficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) on the quality of life (QOL) on such patients in North India...
Production and characterization of human anti-V3 monoclonal antibodies from the cells of HIV-1 infected Indian donorsRaiees Andrabi
Department of Biochemistry, All India Institute of Medical Sciences AIIMS, New Delhi, India
Virol J 9:196. 2012
..The third variable region (V3) is a crucial target on gp120, primarily due to its involvement in co-receptor (CXCR4 or CCR5) binding and presence of epitopes recognized by broadly neutralizing antibodies...
- Neutralization of tier-2 viruses and epitope profiling of plasma antibodies from human immunodeficiency virus type 1 infected donors from India
Raiees Andrabi
Department of Biochemistry, C N Centre, All India Institute of Medical Sciences, New Delhi, India
PLoS ONE 7:e43704. 2012
..Overall, the data suggest that, despite the low immunogenicity of HIV-1 MPER, the antibodies directed to this region may serve as crucial reagents for HIV-1 vaccine design...
- A novel strategy for efficient production of anti-V3 human scFvs against HIV-1 clade C
Rajesh Kumar
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India
BMC Biotechnol 12:87. 2012
....
- Neutralization potential of the plasma of HIV-1 infected Indian patients in the context of anti-V3 antibody content and antiretroviral therapy. [corrected]
Alok Kumar Choudhary
Department of Biochemistry, All India Institute of Medical Sciences, 110029, New Delhi, India
J Microbiol 50:149-54. 2012
..The plasma of antiretroviral-treated patients exhibited higher neutralization potential than that of the drug-naïve plasmas against the four PIs tested which was further evidenced by a follow-up study...
- Antiretroviral drug resistance mutations in the reverse transcriptase gene of HIV-1 isolates from Northern Indian patients: a follow-up study
Shubhasree Dutta Choudhury
Department of Biochemistry, All India Institute of Medical Sciences, Room No 3002, Ansari Nagar, New Delhi, India
Arch Virol 155:563-9. 2010
..The major DRMs found in two 6-month follow-up samples were absent in their baseline blood samples. This is the first follow-up study to determine anti-retroviral drug resistance mutations in Indian HIV patients...
- Evaluation of the current management protocols for prophylaxis against Pneumocystis jiroveci pneumonia and other opportunistic infections in patients living with HIV/AIDS
Sheel Bhadra Jain
Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
AIDS Care 23:846-50. 2011
..Prophylaxis in AIDS patients seems to be a major problem area and a lot of efforts need to be directed toward it since patients suffering from AIDS are bound to have a downhill course despite provision of all available treatment options...
- Cross-neutralizing activity of human anti-V3 monoclonal antibodies derived from non-B clade HIV-1 infected individuals
Raiees Andrabi
Department of Pathology, New York University School of Medicine, New York, NY 10016, USA All India Institute of Medical Sciences, New Delhi, India
Virology 439:81-8. 2013
..These results suggest that clade C V3 is probably weakly immunogenic and that the V3 sequence of CRF02_AG viruses can serve as a plausible template for vaccine immunogen design...
- A study of incidence of AKI in critically ill patients
Mukesh Sharma Paudel
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Ren Fail 34:1217-22. 2012
..There are no new studies from the developing countries looking at AKI in these patients since adoption of uniform Acute Kidney Injury Network (AKIN) criteria...
- Chikungunya infection in India: results of a prospective hospital based multi-centric study
Pratima Ray
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
PLoS ONE 7:e30025. 2012
..A prospective multi-centric study was conducted to evaluate clinical, epidemiological and virological features of chikugunya infection in patients with acute febrile illness from various geographical regions of India...
- Clinical outcomes in typhoid fever: adverse impact of infection with nalidixic acid-resistant Salmonella typhi
Tamilarasu Kadhiravan
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
BMC Infect Dis 5:37. 2005
..These strains are identifiable by their nalidixic acid-resistance. We studied the impact of infection with nalidixic acid-resistant S. typhi (NARST) on clinical outcomes in patients with bacteriologically-confirmed typhoid fever...
- Susceptibility pattern and molecular type of species-specific Candida in oropharyngeal lesions of Indian human immunodeficiency virus-positive patients
Ali Abdul Lattif
School of Life Sciences, Jawaharlal Nehru University, New Delhi, India
J Clin Microbiol 42:1260-2. 2004
..A correlation between CD4(+)-T-cell counts and development of OPC in HIV/AIDS patients was also observed. Molecular typing of C. albicans isolates showed that all were genetically unrelated...
- Defects in blood dendritic cell subsets in HIV-1 subtype c infected Indians
Kamalika Mojumdar
Departments of Microbiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
Indian J Med Res 132:318-27. 2010
..We aimed to characterize the effect of HIV infection on myeloid and plasmacytoid dendritic cell subsets in a group of HIV-1 subtype C infected treated or untreated Indian individuals...
- Outcomes of antiretroviral therapy in a northern Indian urban clinic
Surendra K Sharma
Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India
Bull World Health Organ 88:222-6. 2010
..However, whether they would succeed as part of a national programme in a resource-constrained setting such as India is not clear. The outcomes and specific problems encountered in such a setting have not been adequately studied...
- Epidemiology of nosocomial infections in medicine intensive care unit at a tertiary care hospital in northern India
Shabina Habibi
Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
Trop Doct 38:233-5. 2008
..3% of Escherichia coli were resistant to the third generation cephalosporins. An increased duration of the time spent in intensive care units and days of intervention were associated with incident NI...
- Influenza A: From highly pathogenic H5N1 to pandemic 2009 H1N1. Epidemiology and clinical features
Randeep Guleria
Department of Medicine, All India Institute of Medical Sciences, New Delhi, 110029 India
Indian J Microbiol 49:315-9. 2009
..Fortunately the mortality has been low. Both these new influenza viruses are currently circulating and have different clinical and epidemiological characteristics...
- Heart rate variability in human immunodeficiency virus-positive individuals
Chander Mohan Mittal
Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
Int J Cardiol 94:1-6. 2004
..CONCLUSIONS: HRV is reduced in HIV-seropositive individuals in early stages of infection as well without any clinical evidence of autonomic dysfunction. This may serve as an early marker of future global sympatho-vagal imbalance...
- CDC staging based on absolute CD4 count and CD4 percentage in an HIV-1-infected Indian population: treatment implications
M Vajpayee
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India
Clin Exp Immunol 141:485-90. 2005
....
- Tumor necrosis factor-alpha levels in patients with HIV with wasting in South Asia
N Wig
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
AIDS Patient Care STDS 19:212-5. 2005
..03 +/- 7.61 versus 64.70 +/- 98.70). In conclusion, TNF-alpha levels were higher in HIV patients, regardless of the presence of wasting, compared to normal healthy controls of patients with tuberculosis with wasting...
- Evaluation of CD4 counts and percentages in the HIV infected Indian population
M Vajpayee
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India
Southeast Asian J Trop Med Public Health 35:144-6. 2004
..2%) when compared with Group B (31.6%) and Group C (28.8%), with the counts remaining in the normal range but percentages being severely depressed...
- Antiretroviral therapy: are we aware of adverse effects?
N Wig
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
J Assoc Physicians India 50:1163-71. 2002
..The potential toxicities include gastrointestinal effects, hepatitis, hypersensitivity reactions, cytochrome P450 interactions, mitochondrial toxicity and lipodystrophy syndrome as well as more drug-specific adverse effects...
- Characterization of HIV-1 Gag-specific T cell responses in chronically infected Indian population
S Kaushik
Department of Microbiology, All India Institute of Medical Sciences, New Delhi
Clin Exp Immunol 142:388-97. 2005
....
- Distribution of CCR2 polymorphism in HIV-1-infected and healthy subjects in North India
G Kaur
Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
Int J Immunogenet 34:153-6. 2007
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- Cardiac dysfunction in human immunodeficiency virus (HIV) infected patients in India
Chander Mohan Mittal
Int J Cardiol 107:136-7. 2006
- Heart rate variability and autonomic function tests in HIV positive individuals in India
Ankit Sakhuja
Clin Auton Res 17:193-6. 2007
..The pressor response following handgrip and cold pressor test was blunted in HIV+ patients, and the degree of dysfunction correlated with CD4 cell counts. The extent of autonomic impairment was mild and subclinical...
