Przemyslaw Wielgat

Summary

Publications

  1. doi request reprint Effects of chronic stress and corticosterone on sialidase activity in the rat hippocampus
    Przemyslaw Wielgat
    Department of Clinical Pharmacology, Medical University of Bialystok, Waszyngtona 15A, 15 274, Bialystok, Poland
    Behav Brain Res 222:363-7. 2011
  2. ncbi request reprint Lipopolysaccharide changes sialylation pattern in the mouse central nervous system
    P Wielgat
    Department of Clinical Pharmacology, Medical University of Bialystok, Bialystok, Poland
    J Physiol Pharmacol 63:555-61. 2012
  3. doi request reprint Significance of the cell adhesion molecules and sialic acid in neurodegeneration
    P Wielgat
    Department of Clinical Pharmacology, Medical University of Bialystok, Poland
    Adv Med Sci 57:23-30. 2012
  4. doi request reprint The participation of sialic acids in microglia-neuron interactions
    Przemyslaw Wielgat
    Department of Clinical Pharmacology, Medical University of Bialystok, Waszyngtona 15A, 15 274 Bialystok, Poland
    Cell Immunol 273:17-22. 2012

Collaborators

Detail Information

Publications4

  1. doi request reprint Effects of chronic stress and corticosterone on sialidase activity in the rat hippocampus
    Przemyslaw Wielgat
    Department of Clinical Pharmacology, Medical University of Bialystok, Waszyngtona 15A, 15 274, Bialystok, Poland
    Behav Brain Res 222:363-7. 2011
    ..These results indicate that changes in sialidase activity caused by stress and chronic corticosterone administration reflect disturbances of polysialylated glycoconjugates known to be related to synaptic plasticity in hippocampus...
  2. ncbi request reprint Lipopolysaccharide changes sialylation pattern in the mouse central nervous system
    P Wielgat
    Department of Clinical Pharmacology, Medical University of Bialystok, Bialystok, Poland
    J Physiol Pharmacol 63:555-61. 2012
    ..Given the significance of glycans in the brain biology we can conclude that sialic acids and their receptors Siglec may be crucial regulators of immune response in the CNS...
  3. doi request reprint Significance of the cell adhesion molecules and sialic acid in neurodegeneration
    P Wielgat
    Department of Clinical Pharmacology, Medical University of Bialystok, Poland
    Adv Med Sci 57:23-30. 2012
    ..These mechanisms protect from excitotoxic damage and promote dendritic/spine re-growth. This review briefly focuses on the expression and role of PSA-NCAM in neurodegenerative diseases and its potential application in therapy...
  4. doi request reprint The participation of sialic acids in microglia-neuron interactions
    Przemyslaw Wielgat
    Department of Clinical Pharmacology, Medical University of Bialystok, Waszyngtona 15A, 15 274 Bialystok, Poland
    Cell Immunol 273:17-22. 2012
    ..Our results suggest that interactions between sialic acids and Siglec receptors may protect neuronal integrity during neurodegenerative processes...