Camilla M Whittington

Summary

Publications

  1. ncbi Novel venom gene discovery in the platypus
    Camilla M Whittington
    Faculty of Veterinary Science, The University of Sydney, Regimental Crescent, Camperdown, NSW 2006, Australia
    Genome Biol 11:R95. 2010
  2. ncbi Understanding and utilising mammalian venom via a platypus venom transcriptome
    Camilla M Whittington
    Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia
    J Proteomics 72:155-64. 2009
  3. ncbi A limited role for gene duplications in the evolution of platypus venom
    Emily S W Wong
    Faculty of Veterinary Science, The University of Sydney, Sydney, New South Wales, Australia
    Mol Biol Evol 29:167-77. 2012
  4. ncbi Expression patterns of platypus defensin and related venom genes across a range of tissue types reveal the possibility of broader functions for OvDLPs than previously suspected
    Camilla M Whittington
    Faculty of Veterinary Science, RMC Gunn B19, University of Sydney, NSW 2006, Australia
    Toxicon 52:559-65. 2008
  5. ncbi Identification of natural killer cell receptor clusters in the platypus genome reveals an expansion of C-type lectin genes
    Emily S W Wong
    Faculty of Veterinary Science, University of Sydney, B19 RMC Gunn, Sydney, NSW, 2006, Australia
    Immunogenetics 61:565-79. 2009
  6. ncbi Defensins and the convergent evolution of platypus and reptile venom genes
    Camilla M Whittington
    Faculty of Veterinary Science, University of Sydney, Sydney, New South Wales 2006, Australia
    Genome Res 18:986-94. 2008
  7. ncbi Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials
    Hajime J Yuasa
    Molecular Immunopathology Unit, Discipline of Pathology, School of Medical Sciences, University of Sydney, NSW 2006, Australia
    Comp Biochem Physiol B Biochem Mol Biol 153:137-44. 2009
  8. ncbi Proteomics and deep sequencing comparison of seasonally active venom glands in the platypus reveals novel venom peptides and distinct expression profiles
    Emily S W Wong
    Faculty of Veterinary Science, The University of Sydney, Camperdown, NSW 2006, Australia
    Mol Cell Proteomics 11:1354-64. 2012

Collaborators

Detail Information

Publications8

  1. ncbi Novel venom gene discovery in the platypus
    Camilla M Whittington
    Faculty of Veterinary Science, The University of Sydney, Regimental Crescent, Camperdown, NSW 2006, Australia
    Genome Biol 11:R95. 2010
    ..We have constructed and sequenced a cDNA library from an active platypus venom gland to identify the remaining components...
  2. ncbi Understanding and utilising mammalian venom via a platypus venom transcriptome
    Camilla M Whittington
    Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia
    J Proteomics 72:155-64. 2009
    ..It is therefore hoped that this basic research to identify the constituents of platypus venom will eventually yield novel drugs and new targets for painkillers...
  3. ncbi A limited role for gene duplications in the evolution of platypus venom
    Emily S W Wong
    Faculty of Veterinary Science, The University of Sydney, Sydney, New South Wales, Australia
    Mol Biol Evol 29:167-77. 2012
    ..However, gene duplications alone do not explain the "venome" of the platypus. Other mechanisms, such as alternative splicing and mutation, may be important in venom innovation...
  4. ncbi Expression patterns of platypus defensin and related venom genes across a range of tissue types reveal the possibility of broader functions for OvDLPs than previously suspected
    Camilla M Whittington
    Faculty of Veterinary Science, RMC Gunn B19, University of Sydney, NSW 2006, Australia
    Toxicon 52:559-65. 2008
    ....
  5. ncbi Identification of natural killer cell receptor clusters in the platypus genome reveals an expansion of C-type lectin genes
    Emily S W Wong
    Faculty of Veterinary Science, University of Sydney, B19 RMC Gunn, Sydney, NSW, 2006, Australia
    Immunogenetics 61:565-79. 2009
    ..We have used this new data from platypus to trace the possible evolutionary history of the NK receptor clusters...
  6. ncbi Defensins and the convergent evolution of platypus and reptile venom genes
    Camilla M Whittington
    Faculty of Veterinary Science, University of Sydney, Sydney, New South Wales 2006, Australia
    Genome Res 18:986-94. 2008
    ..Convergent evolution has repeatedly selected genes coding for proteins containing specific structural motifs as templates for venom molecules...
  7. ncbi Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials
    Hajime J Yuasa
    Molecular Immunopathology Unit, Discipline of Pathology, School of Medical Sciences, University of Sydney, NSW 2006, Australia
    Comp Biochem Physiol B Biochem Mol Biol 153:137-44. 2009
    ..The protein encoded by the ancestor gene of IDO1 and IDO2 is likely to have had properties more similar to present day IDO2 than to IDO1...
  8. ncbi Proteomics and deep sequencing comparison of seasonally active venom glands in the platypus reveals novel venom peptides and distinct expression profiles
    Emily S W Wong
    Faculty of Veterinary Science, The University of Sydney, Camperdown, NSW 2006, Australia
    Mol Cell Proteomics 11:1354-64. 2012
    ..These novel venom proteins have potential biomedical and therapeutic applications and provide insights into venom evolution...