Denise A Wells

Summary

Publications

  1. ncbi request reprint Myeloid and monocytic dyspoiesis as determined by flow cytometric scoring in myelodysplastic syndrome correlates with the IPSS and with outcome after hematopoietic stem cell transplantation
    Denise A Wells
    HematoLogics, Inc, 113 1st Avenue N, Seattle, WA 98109, USA
    Blood 102:394-403. 2003
  2. doi request reprint Normalization of bone marrow aspirates for hemodilution in flow cytometric analyses
    Michael R Loken
    HematoLogics, Inc Seattle, Washington 98121, USA
    Cytometry B Clin Cytom 76:27-36. 2009
  3. ncbi request reprint Array-based karyotyping in plasma cell neoplasia after plasma cell enrichment increases detection of genomic aberrations
    Barbara K Zehentner
    HematoLogics Inc, 3161 Elliott Ave, Ste 200, Seattle, WA 98121, USA
    Am J Clin Pathol 138:579-89. 2012
  4. ncbi request reprint The role of flow cytometry in myelodysplastic syndromes
    Michael R Loken
    HematoLogics, Inc, Seattle, Washington 98121, USA
    J Natl Compr Canc Netw 6:935-41. 2008
  5. doi request reprint A minority of concurrent monoclonal lymphocytes and plasmacytic cells sharing light chains are genetically related in putative lymphoplasmacytic lymphoma
    Barbara K Zehentner
    HematoLogics Inc, 3161 Elliott Ave, Seattle, WA 98121, USA
    Leuk Res 35:1597-604. 2011
  6. pmc Validation of a flow cytometric scoring system as a prognostic indicator for posttransplantation outcome in patients with myelodysplastic syndrome
    Bart L Scott
    Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Blood 112:2681-6. 2008
  7. doi request reprint Phenotypic abnormalities strongly reflect genotype in patients with unexplained cytopenias
    Jevon A Cutler
    HematoLogics, Seattle, Washington, 98121, USA
    Cytometry B Clin Cytom 80:150-7. 2011
  8. ncbi request reprint Flow cytometry in myelodysplastic syndromes: report from a working conference
    Michael R Loken
    HematoLogics, Inc, Seattle, USA
    Leuk Res 32:5-17. 2008
  9. doi request reprint Intraclonal heterogeneity in concomitant monoclonal lymphocyte and plasma cell populations: combining flow cytometric cell sorting with molecular monoclonality profiling
    Barbara K Zehentner
    HematoLogics, Inc, Seattle, WA, USA
    Clin Lymphoma Myeloma Leuk 13:214-7. 2013
  10. doi request reprint Basal levels of CD34 positive cells in peripheral blood differ between individuals and are stable for 18 months
    Lisa Eidenschink
    HematoLogics, Inc, Seattle, Washington, USA
    Cytometry B Clin Cytom 82:18-25. 2012

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Myeloid and monocytic dyspoiesis as determined by flow cytometric scoring in myelodysplastic syndrome correlates with the IPSS and with outcome after hematopoietic stem cell transplantation
    Denise A Wells
    HematoLogics, Inc, 113 1st Avenue N, Seattle, WA 98109, USA
    Blood 102:394-403. 2003
    ..01, P =.02, and P =.03, respectively). These data suggest that FCSS is useful in assessing marrows for diagnosis of MDS and in determining the prognostic outcome in patients with this disorder...
  2. doi request reprint Normalization of bone marrow aspirates for hemodilution in flow cytometric analyses
    Michael R Loken
    HematoLogics, Inc Seattle, Washington 98121, USA
    Cytometry B Clin Cytom 76:27-36. 2009
    ....
  3. ncbi request reprint Array-based karyotyping in plasma cell neoplasia after plasma cell enrichment increases detection of genomic aberrations
    Barbara K Zehentner
    HematoLogics Inc, 3161 Elliott Ave, Ste 200, Seattle, WA 98121, USA
    Am J Clin Pathol 138:579-89. 2012
    ..We conclude that aCGH after plasma cell enrichment, in combination with FISH, is a valuable approach for routine clinical use in achieving a more complete genetic characterization of patients with PCN...
  4. ncbi request reprint The role of flow cytometry in myelodysplastic syndromes
    Michael R Loken
    HematoLogics, Inc, Seattle, Washington 98121, USA
    J Natl Compr Canc Netw 6:935-41. 2008
    ..This is useful, not only to facilitate diagnosis, but to provide prognostic information that may be complementary to the conventional classification schemes and scoring systems...
  5. doi request reprint A minority of concurrent monoclonal lymphocytes and plasmacytic cells sharing light chains are genetically related in putative lymphoplasmacytic lymphoma
    Barbara K Zehentner
    HematoLogics Inc, 3161 Elliott Ave, Seattle, WA 98121, USA
    Leuk Res 35:1597-604. 2011
    ..These techniques are requisite in future clinical studies for diagnosis and prognosis in these diseases...
  6. pmc Validation of a flow cytometric scoring system as a prognostic indicator for posttransplantation outcome in patients with myelodysplastic syndrome
    Bart L Scott
    Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Blood 112:2681-6. 2008
    ..7; P = .02). This analysis confirmed that FCSS scores are predictive of posttransplantation outcomes in patients with MDS even after adjusting for risk factors such as marrow myeloblast percentage and IPSS score...
  7. doi request reprint Phenotypic abnormalities strongly reflect genotype in patients with unexplained cytopenias
    Jevon A Cutler
    HematoLogics, Seattle, Washington, 98121, USA
    Cytometry B Clin Cytom 80:150-7. 2011
    ..Multidimensional flow cytometry (FCM) can identify myelomonocytic cells with aberrant phenotypes often not seen by standard morphology...
  8. ncbi request reprint Flow cytometry in myelodysplastic syndromes: report from a working conference
    Michael R Loken
    HematoLogics, Inc, Seattle, USA
    Leuk Res 32:5-17. 2008
    ..Clearly defined aberrancies on myeloid immature and maturing cells are now identified with possible impact on diagnosis, classification and prognostication in the near feature...
  9. doi request reprint Intraclonal heterogeneity in concomitant monoclonal lymphocyte and plasma cell populations: combining flow cytometric cell sorting with molecular monoclonality profiling
    Barbara K Zehentner
    HematoLogics, Inc, Seattle, WA, USA
    Clin Lymphoma Myeloma Leuk 13:214-7. 2013
    ..Understanding how many clonal processes (molecular profiles) are present can help guide patient monitoring throughout treatment and potentially identify patients with worse outcomes...
  10. doi request reprint Basal levels of CD34 positive cells in peripheral blood differ between individuals and are stable for 18 months
    Lisa Eidenschink
    HematoLogics, Inc, Seattle, Washington, USA
    Cytometry B Clin Cytom 82:18-25. 2012
    ..A reproducible analytic approach was used in three independent clinical trials in which multiple sequential assays were obtained from the same individual...
  11. ncbi request reprint Flow cytometric detection of nonneoplastic antigenic polymorphisms of donor origin after allogeneic marrow transplant: a report of two cases
    Linlin Wang
    HematoLogics, Seattle, WA 98109, USA
    Am J Clin Pathol 122:135-40. 2004
    ..The distinction of these phenotypic abnormalities from neoplastic changes such as secondary myelodysplasias or relapse of original disease is important in posttransplantation monitoring of hematopoietic diseases...
  12. doi request reprint Detection of genomic abnormalities in multiple myeloma: the application of FISH analysis in combination with various plasma cell enrichment techniques
    Luise Hartmann
    Department of Molecular Analysis, HematoLogics, 3161 Elliott Avenue, Seattle, WA 98121, USA
    Am J Clin Pathol 136:712-20. 2011
    ..FISH results are highly dependent on the chosen enrichment method. We describe the evaluation of different techniques applicable for various laboratory settings and specimen parameters...
  13. ncbi request reprint Minimal disease detection and confirmation in hematologic malignancies: combining cell sorting with clonality profiling
    Barbara K Zehentner
    HematoLogics, Inc, Seattle, WA 98109, USA
    Clin Chem 52:430-7. 2006
    ..In this study we demonstrate the technical application of flow cytometry and cell sorting combined with gene-rearrangement clonality profiling to detect and confirm minimal disease in 2 leukemia and 2 lymphoma cases...
  14. ncbi request reprint JAK2V617F mutation can occur exclusively in the erythroid lineage and be absent in granulocytes and progenitor cells in classic myeloproliferative disorders
    Barbara K Zehentner
    Am J Hematol 81:806-7. 2006
  15. ncbi request reprint Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: Consensus statements and report from a working conference
    Peter Valent
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Leuk Res 31:727-36. 2007
    ..Respective algorithms and recommendations should facilitate diagnostic and prognostic evaluations in MDS, selection of patients for therapies, and the conduct of clinical trials...
  16. ncbi request reprint On flow cytometry in myelodysplastic syndromes, with caveats
    Denise A Wells
    Leuk Res 32:209-10. 2008