Hongen Wei

Summary

Publications

  1. ncbi request reprint The apoptotic perspective of autism
    Hongen Wei
    Central Laboratory, Shanxi Provincial People s Hospital, Affiliate of Shanxi Medical University, Taiyuan, China Electronic address
    Int J Dev Neurosci 36:13-8. 2014
  2. ncbi request reprint Brain IL-6 and autism
    H Wei
    Central Laboratory, Shanxi Provincial People s Hospital, Affiliate of Shanxi Medical University, Taiyuan, China Electronic address
    Neuroscience 252:320-5. 2013
  3. doi request reprint Alteration of brain volume in IL-6 overexpressing mice related to autism
    Hongen Wei
    Central Laboratory, Shanxi Provincial People s Hospital, Taiyuan, China
    Int J Dev Neurosci 30:554-9. 2012
  4. pmc IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation
    Hongen Wei
    Department of Neurochemistry, NY State Institute for Basic Research in Developmental Disabilities, New York, USA
    J Neuroinflammation 8:52. 2011
  5. pmc The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome
    Hongen Wei
    Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, New York, New York, United States of America
    PLoS ONE 7:e36981. 2012
  6. doi request reprint Up-regulation of Ras/Raf/ERK1/2 signaling impairs cultured neuronal cell migration, neurogenesis, synapse formation, and dendritic spine development
    Kun Yang
    Department of Neurochemistry, NY State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, New York, NY, 10314, USA
    Brain Struct Funct 218:669-82. 2013
  7. doi request reprint Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors
    Hongen Wei
    Department of Neurochemistry, NY State Institute for Basic Research in Developmental Disabilities, New York, NY 10314, USA
    Biochim Biophys Acta 1822:831-42. 2012
  8. pmc Abnormal cell properties and down-regulated FAK-Src complex signaling in B lymphoblasts of autistic subjects
    Hongen Wei
    Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, New York, New York 10314, USA
    Am J Pathol 179:66-74. 2011

Detail Information

Publications8

  1. ncbi request reprint The apoptotic perspective of autism
    Hongen Wei
    Central Laboratory, Shanxi Provincial People s Hospital, Affiliate of Shanxi Medical University, Taiyuan, China Electronic address
    Int J Dev Neurosci 36:13-8. 2014
    ..It has been demonstrated a possible association between neural cell death and autism. Here, the abnormal apoptosis found in autism from postmortem and animal studies was reviewed and the possible mechanism was discussed. ..
  2. ncbi request reprint Brain IL-6 and autism
    H Wei
    Central Laboratory, Shanxi Provincial People s Hospital, Affiliate of Shanxi Medical University, Taiyuan, China Electronic address
    Neuroscience 252:320-5. 2013
    ..Further studies to investigate whether IL-6 could be used for therapeutic interventions in autism would be of great significance. ..
  3. doi request reprint Alteration of brain volume in IL-6 overexpressing mice related to autism
    Hongen Wei
    Central Laboratory, Shanxi Provincial People s Hospital, Taiyuan, China
    Int J Dev Neurosci 30:554-9. 2012
    ..These results indicate that IL-6 elevation in the brain could mediate neuroanatomical abnormalities. Taking together with our previous findings, a mechanism by which IL-6 may be involved in the pathogenesis of autism is proposed...
  4. pmc IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation
    Hongen Wei
    Department of Neurochemistry, NY State Institute for Basic Research in Developmental Disabilities, New York, USA
    J Neuroinflammation 8:52. 2011
    ..Recent evidence shows that IL-6 has a crucial role in the development and plasticity of CNS...
  5. pmc The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome
    Hongen Wei
    Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, New York, New York, United States of America
    PLoS ONE 7:e36981. 2012
    ..These findings suggest that memantine may exert its therapeutic capacity through a stimulatory effect on dendritic spine maturation and excitatory synapse formation, as well as promoting adhesion of CGCs...
  6. doi request reprint Up-regulation of Ras/Raf/ERK1/2 signaling impairs cultured neuronal cell migration, neurogenesis, synapse formation, and dendritic spine development
    Kun Yang
    Department of Neurochemistry, NY State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, New York, NY, 10314, USA
    Brain Struct Funct 218:669-82. 2013
    ..Together, these results suggest that the up-regulation of the Raf/ERK signaling pathway may contribute to the pathogenesis of autism through both its impairment of cortical neuron development and causing neural circuit imbalances...
  7. doi request reprint Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors
    Hongen Wei
    Department of Neurochemistry, NY State Institute for Basic Research in Developmental Disabilities, New York, NY 10314, USA
    Biochim Biophys Acta 1822:831-42. 2012
    ..These findings suggest that IL-6 elevation in the brain could mediate autistic-like behaviors, possibly through the imbalances of neural circuitry and impairments of synaptic plasticity...
  8. pmc Abnormal cell properties and down-regulated FAK-Src complex signaling in B lymphoblasts of autistic subjects
    Hongen Wei
    Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, New York, New York 10314, USA
    Am J Pathol 179:66-74. 2011
    ....