Plasma ghrelin modulation in gastric band operation and sleeve gastrectomyYong Wang
Hepatobiliary Department, Shengjing Hospital, China Medical University, 36 Sanhao Street, Shenyang, 110004, China
Obes Surg 19:357-62. 2009
..The purpose of this study is to investigate the changes in plasma ghrelin levels and hypothalamic ghrelin receptor expression with weight loss achieved through these surgeries...
[Expression of renal aquaporin 2 after circulatory arrest]Yong Wang
Department of Anesthesia, Shengjing Hospital Affiliated China Medical University, Shenyang 110004, Liaoning, China
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 20:210-3. 2008
..To investigate the inhibition of renal aquaporin 2 (AQP2) and AQP2 mRNA expression due to circulatory arrest...
- Small-dose naloxone combined with epinephrine improves the resuscitation of cardiopulmonary arrest
Yong Wang
Department of Anesthesia, Shengjing Hospital, China Medical University, Shenyang 110004, China
Am J Emerg Med 26:898-901. 2008
..To investigate if naloxone combined with epinephrine can increase the resuscitation rate in cardiac arrest rat models induced by asphyxia...
- Downregulation of AQP2 and AQP2 mRNA expression in kidney medulla of rats with bile duct ligation
Yong Wang
Department of Hepatobiliary, Second Affiliated Hospital Shengjing Hospital, China Medical University, Shenyang 110004, China
Hepatobiliary Pancreat Dis Int 6:636-40. 2007
..This investigation evaluated renal function and renal aquaporin 2 (AQP2) expression changes in obstructive jaundice...
- Roux-en-Y gastric bypass-induced improvement of glucose tolerance and insulin resistance in type 2 diabetic rats are mediated by glucagon-like peptide-1
Yuan Liu
Department of General Surgery, Shengjing Hospital, China Medical University, Shenyang, China
Obes Surg 21:1424-31. 2011
..The aim of this study was to investigate the effects of Roux-en-Y gastric bypass (RYGB) on glucose tolerance and insulin resistance in type 2 diabetic rats and the possible mechanisms involved in this process...
Sleeve gastrectomy prevents lipoprotein receptor-1 expression in aortas of obese ratsJie Bai
Department of General Surgery, China Medical University and the affiliated Shengjing Hospital, Shenyang 110004, Liaoning Province, China
World J Gastroenterol 17:3739-44. 2011
..To investigate the effects of sleeve gastrectomy on adipose tissue infiltration and lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) expression in rat aortas...
- Naloxone combined with epinephrine decreases cerebral injury in cardiopulmonary resuscitation
Yong Wang
Department of Anesthesia, Shengjing Hospital, China Medical University, Shenyang, China
J Emerg Med 39:296-300. 2010
....
- Combination of bypassing stomach and vagus dissection in high-fat diet-induced obese rats-a long-term investigation
Yong Wang
Hepatobiliary Department, Shengjing Hospital, 36 Sanhao Street, Shenyang, 110004, China
Obes Surg 20:375-9. 2010
..Gastric bypass is the most popular technique in obesity therapy. We hypothesize that bypass surgery can help to control the body weight in morbid obesity, and this effect can be enhanced by vagus dissection...
- Sleeve gastrectomy relieves steatohepatitis in high-fat-diet-induced obese rats
Yong Wang
Hepatobiliary Department, Shengjing Hospital, China Medical University, Shenyang, 110004, China
Obes Surg 19:921-5. 2009
..Sleeve gastrectomy is thought to decrease the appetite and body weight of morbid obesity patients in the clinic. The purpose is to investigate the effect of sleeve gastrectomy on preventing steatohepatitis in morbid obesity rats...
- The expression of nuclear factor kappa B in inflammation-induced rat corneal neovascularization
Ming chang Zhang
Department of Ophthalmology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Ocul Immunol Inflamm 14:359-65. 2006
..To investigate the involvement of the nuclear-transfactor-kappa B (NF-kappa B) in the rat model of inflammation-induced corneal neovascularization (CNV)...
- [Pay attention to basic and clinical research of pterygium]
Ming chang Zhang
Department of Ophthalmology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
Zhonghua Yan Ke Za Zhi 43:868-71. 2007
..The study of the pathogenesis and clinical guideline for the diagnosis and treatment of pterygium should be emphasized in order to reduce the occurrence and recurrence of pterygium...
- Comparative study on cerebral injury after open heart surgery in patients with congenital and rheumatic heart disease
Yong Wang
Department of Cardiovascular Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
Chin J Traumatol 8:249-52. 2005
..To comparatively study the different effects of open heart surgery on brain tissues of patients with congenital and rheumatic heart disease...
- Taurine may prevent diabetic rats from developing cardiomyopathy also by downregulating angiotensin II type2 receptor expression
Changyun Li
Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430022, China
Cardiovasc Drugs Ther 19:105-12. 2005
..This study investigates the roles of taurine and AT2 in rats with streptozotocin (STZ)-induced diabetic cardiomyopathy...
- [Inhibition of rat corneal neovascularization by inhibitor of nuclear factor-kappaB]
Yong Wang
Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Zhonghua Yan Ke Za Zhi 41:1124-8. 2005
..To observe the effects and mechanism of pyrrolidine dithiocarbamate (PDTC) on inhibiting corneal neovascularization...
- Expression and purification of invasion plasmid antigen C of Shigella flexneri
Su xia Sun
Department of Epidemiology, First Military Medical University, Guangzhou 510515, China
Di Yi Jun Yi Da Xue Xue Bao 23:230-2. 2003
..To induce the expression of and purify invasion plasmid antigen C (IpaC) of Shigella flexneri for studying the pathogenesis of Shigella flexneri...
- Renaturation and purification of ApxII toxin of Actinobacillus pleuropneumoniae
Chunlai Wang
Division of Bacterial Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150001, PR China
Protein Expr Purif 52:441-5. 2007
..The result indicated that E. coli expressed recombinant ApxII toxin has good fidelity, which makes it possible to produce this valuable antigen for vaccine preparation or diagnosis...
- Association of the aspartic acid-repeat polymorphism in the asporin gene with age at onset of knee osteoarthritis in Han Chinese population
Dongquan Shi
The Center of Diagnosis and Treatment for Joint Disease, Drum Tower Hospital, affiliated to Medical School of Nanjing University, Zhongshan Road 321, Nanjing, 210008 Jiangsu, China
J Hum Genet 52:664-7. 2007
..The average age at onset of patients with the D13/D13 genotype (mean: 56.1, SD: 11.1) was older than those without the D13/D13 genotype (mean: 53.0, SD: 9.9) (P = 0.013). Our study further highlighted the significance of asporin in OA...
- Predicting gene ontology functions from protein's regional surface structures
Zhi Ping Liu
Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100080, China
BMC Bioinformatics 8:475. 2007
..For example, CASTp provides identification and measurements of surface accessible pockets as well as interior inaccessible cavities...
- Laparoscopy-assisted orchiopexy for recurrent undescended testes in children
Qiangsong Tong
Department of Pediatric Surgery, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430022, China
J Pediatr Surg 44:806-10. 2009
..The laparoscopy-assisted procedure is described for securing the testis in the scrotum in patients with a past history of open orchidopexy and testes in an unsatisfactory position...
- Composite tissue allograft transplantation of cephalocervical skin flap and two ears
Hui Q Jiang
Department of Burn and Plastic Surgery, Jinling Hospital, Nanjing, China
Plast Reconstr Surg 115:31e-35e; discussion 36e-37e. 2005
- Diagnosis and treatment of biliary atresia: a retrospective study
Shao Tao Tang
Department of Pediatric Surgery, Wuhan Union Hospital, Huazhong Science and Technology University, Wuhan 430022, China
Hepatobiliary Pancreat Dis Int 4:108-12. 2005
..The purpose of this study was to investigate the diagnosis, treatment and postoperative outcome of BA and to explore new diagnostic and therapeutic strategies...
- Adiponectin downregulates hyperglycemia and reduces pancreatic islet apoptosis after roux-en-y gastric bypass surgery
Fang Chai
Department of General Surgery, China Medical University Affiliated Shengjing Hospital, 36 Sanhao Street, Shenyang, 110004, China
Obes Surg 21:768-73. 2011
..The general objective was to explore whether RYGB could reduce beta cells apoptosis and what roles adiponectin played in downregulating hyperglycemia after RYGB...
- Gastric bypass surgery alters the mechanisms of insulin resistance in the adipose tissue of GK rats
Jibin Li
Department of General Surgery, Shengjing Hospital, China Medical University, Shenyang 110004, PR China
Mol Med Rep 6:1111-6. 2012
....
- Safety and efficacy of biodegradable polymer-coated sirolimus-eluting stents in "real-world" practice: 18-month clinical and 9-month angiographic outcomes
Yaling Han
Department of Cardiology, Shenyang Northern Hospital, Shenyang, China
JACC Cardiovasc Interv 2:303-9. 2009
..This study sought to evaluate the safety and efficacy of a biodegradable polymer-coated sirolimus-eluting stent (Excel, JW Medical System, Weihai, China) with 6-month dual antiplatelet therapy in daily practice...
- Deficient CD4+CD25+ T regulatory cell function in patients with abdominal aortic aneurysms
Mingdi Yin
Department of Vascular Surgery, First Hospital, China Medical University, Shenyang, China
Arterioscler Thromb Vasc Biol 30:1825-31. 2010
..This work was aimed to assess the possibly altered function of peripheral CD4(+)CD25(+) T regulatory cells (Tregs) that might breakdown immunologic self-tolerance in AAA patients...
- Analysis on multi-domain cooperation for predicting protein-protein interactions
Rui Sheng Wang
School of Information, Renmin University of China, Beijing 100872, China
BMC Bioinformatics 8:391. 2007
..Revealing multi-domain cooperation can provide deep insights into the essential mechanism of protein-protein interactions at the domain level and be further exploited to improve the accuracy of protein interaction prediction...
- ATP binding cassette G8 T400K polymorphism may affect the risk of gallstone disease among Chinese males
Yong Wang
Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, Shanghai 200025, China
Clin Chim Acta 384:80-5. 2007
....
- Expression change of interleukin-8 gene in rabbit basilar artery after subarachnoid hemorrhage
Yong Wang
Department of Neurosurgery, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, China
Neurosci Bull 23:151-5. 2007
..To study the expression change of interleukin-8 (IL-8) gene in the basilar artery of rabbit and the effect of IL-8 on the development of cerebral vasospasm induced by experimental subarachnoid hemorrhage (SAH)...
- Cystic fibrosis transmembrane conductance regulator (CFTR) gene 5T allele may protect against prostate cancer: a case-control study in Chinese Han population
Di Qiao
Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China
J Cyst Fibros 7:210-4. 2008
..Mutations and polymorphisms in the CFTR gene are responsible for cystic fibrosis (CF), and the incidence of prostate cancer in CF patients seemed to be lower than expected...
- 6-deoxyerythronolide B production through chromosomal localization of the deoxyerythronolide B synthase genes in E. coli
Yong Wang
Department of Chemical and Biological Engineering, Tufts University, Medford, MA 02155, USA
Metab Eng 10:33-8. 2008
..As determined by MS analysis, average production levels for YW9 were 0.47 (22 degrees C), 0.52 (30 degrees C), and 0.11 (37 degrees C)mg/L...
- Protein domain annotation with integration of heterogeneous information sources
Xing Ming Zhao
ERATO Aihara Complexity Modelling Project, JST, Tokyo 151 0064, Japan
Proteins 72:461-73. 2008
..We show that the integration of heterogeneous information sources improves not only prediction accuracy but also annotation reliability when compared with the methods using only individual information sources...
- Bridging protein local structures and protein functions
Zhi Ping Liu
Academy of Mathematics and Systems Science, Chinese Academy of Sciences, 100080, Beijing, China
Amino Acids 35:627-50. 2008
..We also discuss remaining problems and possible directions for this exciting and challenging area...
- Effect of p27Kip1 inhibition on proliferation of bovine corneal endothelial cells by RNA interference
Yukan Huang
Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
J Huazhong Univ Sci Technolog Med Sci 28:211-5. 2008
..It is concluded that shRNA-p27Kip1 could down-regulate the expression of p27Kip1 effectively and increase the proliferation of bCEC. RNA interference (RNAi) may be an effective means to promote the proliferation of CEC...
- Analysis of protein surface patterns by pocket similarity network
Zhi Ping Liu
Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100080, China
Protein Pept Lett 15:448-55. 2008
....
- Protein domain annotation with predicted domain-domain interaction networks
Xing Ming Zhao
ERATO Aihara Complexity Modelling Project, JST, Tokyo 151 0064, Japan
Protein Pept Lett 15:456-62. 2008
..Specially, domain annotation is formalized as a multi-class classification problem in this work. The numerical experiments on InterPro domains show promising results, which proves the efficiency of our proposed methods...
- Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line
Hector Biliran
Department of Pathology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
Clin Cancer Res 11:6075-86. 2005
....
- A novel DNA vaccine for protective immunity against virulent Mycobacterium bovis in mice
Siguo Liu
Division of Bacterial Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 15000, PR China siguo
Immunol Lett 117:136-45. 2008
..This suggests that fusion DNA vaccine represent a promising approach for the prevention of bTB...
- [Regulation of axon guidance cue netrin-1 on angiogenesis]
Yun Yang
Department of Gynecology and Obstetrics, Union Hospital of Huazhong University of Science and Technology, Wuhan 430022, China
Zhonghua Yi Xue Za Zhi 87:475-8. 2007
..To study the effect of netrin-1, an axon guidance cue, on angiogenesis...
- Association of ACE gene polymorphism with genetic susceptibility to systemic lupus erythematosus in a Chinese population: a family-based association study
Jianhua Xu
Department of Rheumatology, First Affiliated Hospital, Hefei, China
J Rheumatol 34:2408-11. 2007
..Family-based association analysis was performed to investigate whether the angiotensin-converting enzyme (ACE)-G261T and ACE-A592G polymorphisms are risk factors for systemic lupus erythematosus (SLE) in a Chinese population...
- Optimization of 2-phenylaminoimidazo[4,5-h]isoquinolin-9-ones: orally active inhibitors of lck kinase
Daniel R Goldberg
Department of Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, Inc, 900 Ridgebury Road, Ridgefield, Connecticut 06877, USA
J Med Chem 46:1337-49. 2003
....
- Mechanism of altered TNF-alpha expression by macrophage and the modulatory effect of Panax notoginseng saponins in scald mice
Yong Wang
Institute of Burn Research, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
Burns 32:846-52. 2006
..PNS might play an anti-inflammatory effect by inhibiting NF-kappaB activity and TNF-alpha mRNA expression...
- Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats
Yong Wang
Department of Traditional Chinese Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, PR China
J Ethnopharmacol 98:37-43. 2005
..01). In conclusion, SN decreases the mRNA expression of TNF-alpha and IL-1beta by inhibiting the NF-kappaB binding activity, which is mediated through up-regulating the IkappaB-alpha expression of PMs and synoviocytes in AA rats...
- A microsatellite polymorphism (tttta)n in the promoter of the CYP11a gene in Chinese women with polycystic ovary syndrome
Yong Wang
Human Genetic Identification Laboratory, Medical School of Nanjing University, Nanjing, China
Fertil Steril 86:223-6. 2006
....
- Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation
Sohini Mukherjee
Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Science 312:1211-4. 2006
..The acetylation on MAPKK6 directly competed with phosphorylation, preventing activation of the modified protein. This covalent modification may be used as a general regulatory mechanism in biological signaling...
- A novel glucokinase activator modulates pancreatic islet and hepatocyte function
Alexander M Efanov
Lilly Research Laboratories, Eli Lilly and Company, Essener Bogen 7, 22419 Hamburg, Germany
Endocrinology 146:3696-701. 2005
....
- Crystal structure of Escherichia coli RNase D, an exoribonuclease involved in structured RNA processing
Yuhong Zuo
Department of Biochemistry and Molecular Biology, University of Miami School of Medicine, PO Box 016129, Miami, FL 33101, USA
Structure 13:973-84. 2005
..The ring-shaped architecture of E. coli RNase D and the HRDC domains likely play a major role in determining the substrate specificity of this exoribonuclease...
- Polymorphisms of the peroxisome proliferator-activated receptor-gamma and its coactivator-1alpha genes in Chinese women with polycystic ovary syndrome
Yong Wang
Human Genetic Identification Laboratory, Medical School of Nanjing University, Nanjing, China
Fertil Steril 85:1536-40. 2006
....
- [Microsatellite polymorphism of (tttta) n in the promoter of CYP11a gene in Chinese women with polycystic ovary syndrome]
Yong Wang
Teaching and Research Section of Histology and Embryology, Medical School of Nanjing University, Nanjing 210093, China
Zhonghua Yi Xue Za Zhi 85:3396-400. 2005
..To investigate the distribution of (tttta) n microsatellite polymorphism in the promoter of CYP11a gene in Chinese women with polycystic ovary syndrome (PCOS) and the relationship between such polymorphism and PCOS...
- A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats
Conrad W Hummel
Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA
J Med Chem 48:6772-5. 2005
....
- [Allograft transplantation with compound tissue of two ears and skin of head and neck: A report of 1 case, China]
Hui-qing Jiang
Department of Burn and Plastic Surgery, General Hospital of Nanjing Command, Nanjing 210002, China
Zhonghua Zheng Xing Wai Ke Za Zhi 19:416-9. 2003
..Good tissue matching and combined use of currently available immunosuppressants can prevent hyperacute and acute rejection efficiently...
- Revealing divergent evolution, identifying circular permutations and detecting active-sites by protein structure comparison
Luonan Chen
Institute of Systems Biology, Shanghai University, Shanghai 200444, China
BMC Struct Biol 6:18. 2006
....
- The role of X-linked genes in breast cancer
Archana Thakur
Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA
Breast Cancer Res Treat 93:135-43. 2005
..Increased understanding of the role of X-linked genes and genetic pathways will provide the strategies to develop the molecular therapeutics to treat and prevent reproductive related cancers...
- Structural basis for processivity and single-strand specificity of RNase II
Yuhong Zuo
Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, P O Box 016129, Miami, FL 33101, USA
Mol Cell 24:149-56. 2006
..The presence of the clamp and the narrow channel provides an explanation for the processivity of RNase II and for why its action is limited to single-stranded RNA...
- Regularity of hypoxia inducible factor 1 alpha expression in acute myocardial ischaemia in rats
Zhi-gang Li
Department of Forensic Science, Sun Yat-sen University, Guangzhou 510080, China
Chin Med J (Engl) 120:162-5. 2007
- Discrimination of outer membrane proteins by a new measure of information discrepancy
Zikai Wu
Department of Applied Mathematics, Dalian University of Technology, Dalian 116024, China
Protein Pept Lett 14:37-44. 2007
..Furthermore, this method is able to correctly exclude alpha-helical membrane proteins at an accuracy of 100%...
- Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese
Qing Jiang
The Center of Diagnosis and Treatment for Joint Disease, Drum Tower Hospital Affiliated to Medical School of Nanjing University, Zhongshan Road 321, Nanjing, 210008, Jiangsu, China
J Hum Genet 51:1068-72. 2006
..Thus, the association of the D14 allele with knee OA susceptibility was replicated in Han Chinese. This was the first instance that association of the OA susceptibility gene was definitely replicated between different ethnic groups...
- Lipoprotein lipase gene polymorphism at the PvuII locus and serum lipid levels in Guangxi Hei Yi Zhuang and Han populations
Ruixing Yin
Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital, Guangxi Medical University, 22 Shuangyong Road, Nanning 530021, China
Clin Chem Lab Med 44:1416-21. 2006
..Therefore, the present study was undertaken to compare the effects of lipoprotein lipase gene polymorphism at the PvuII locus on lipid levels in the Guangxi Hei Yi Zhuang and Han populations...
- Gene expression profile of CD4+ T cells reveals an interferon signaling suppression associated with progression of experimental Schistosoma japonicum infection
Min-jun Ji
Molecular- and Immuno-parasitology, Research Laboratory, Nanjing Medical University, 140 Hanzhong Road, Nanjing, Jiangsu 210029, PR China
Cell Immunol 224:55-62. 2003
..japonicum...
- [Study on the prevalence of the "high pathogenicity island" of Yersinia enterocolitica WA in Enterotoxigenic, Enteropathogenic and Enteroaggregative E. coli strains]
Yong Wang
The Epidemic Prevention Brigade of Health, General Logistic Department, People's Liberation Army, Beijing 100039, China
Zhonghua Liu Xing Bing Xue Za Zhi 24:213-5. 2003
..coli were from different ancient bacterias. At the same time, the high positivity rate of HPI in E. coli might be crucial to virulence change, virulence evolution and virulence regulation in E. coli...
- Increase of beta1-adrenergic receptor gene expression induced by nicotine in hippocampal slice of rat
Yong Wang
Department of Pharmacology, Sun Yat-sen University of Medical Science, Guangzhou 510089, China
Acta Pharmacol Sin 24:1281-6. 2003
..The peak of protein occurred later but higher than that of mRNA level. CONCLUSION: Both expression of beta1- adrenergic receptor gene transcription and post-transcriptional protein level in rat hippocampus were altered by nicotine...
- [Surgical treatment of tonsillar cancer]
Li-qiang Zhang
Department of Oto-Rhino-Laryngology, Qilu Hospital of Shandong University, Jinan 250012, China
Zhonghua Zhong Liu Za Zhi 25:596-8. 2003
..When combined with postoperative radiotherapy, the survival rate and quality of life of patients can be improved...
- [Effect of low intensity and very high frequency electromagnetic radiation on occupationally exposed personnel]
Zheng-Quan Yuan
Epidemic Prevention Brigade, General Logistics Department, PLA, Beijing 100039, China
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 22:267-9. 2004
..01). CONCLUSIONS: Low-intensity VHF radiation can decrease the nervous system function in occupationally exposed personnel and induce increase in some kinds of enzymes and immunoglobulins...
- [Prediction of T-cell epitopes from schistosoma japonicum 28 kDa glutathione-S-transferase and identification of their Th1 type T-cell epitopes]
Guang Fu Li
Department of Pathogenic Biology, Nanjing Medical University, Nanjing 210029, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:352-5. 2004
..To predict T-cell epitopes of recombinant schistosoma japonicum 28 kDa glutathione-S-transferase(GST) with software and identify the Th1 type T-cell epitopes by experiments...
- Ectopic expression of a c1-I allele from maize inhibits pigment formation in the flower of transgenic tobacco
Bojun Chen
Life Sciences Center, College of Life Sciences, Peking University, Beijing 100871, China
Mol Biotechnol 26:187-92. 2004
..Thus, this c1-I allele appears to act as a repressor in pigment formation and function through titration of a bHLH factor...
- [Studies on the characteristic of interferon-gamma mediating resistance in mice infected with Schistosoma japonicum]
Min-jun Ji
Institute for Molecular Biology of Medicine, Nanjing Medial University, Nanjing 210029, China
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 22:29-32. 2004
..CONCLUSION: There is a dramatic inhibition of IFN-gamma pathway and IFN-gamma-dependent anti-infective immunity during the infection of S. japonicum...
- A comparison between polymeric microsphere and bacterial vectors for macrophage P388D1 gene delivery
Saba Parsa
Department of Chemical and Biological Engineering, Tufts University, Medford, MA 02155, USA
Pharm Res 25:1202-8. 2008
..The purpose of this study was to compare bacterial and polymeric gene delivery devices for the ability to deliver plasmid DNA to a murine macrophage P388D1 cell line...
- Effect of block deletions in the C-terminus on the functional expression of human anion exchanger 1 (AE1)
Yong Wang
Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Rui Jin Hospital, Shanghai Jiao Tong University, School of Medicine Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China
Mol Membr Biol 24:65-73. 2007
..These results demonstrate that the studied residues in the AE1 C-terminus differently affect the expression, membrane trafficking and functional folding of AE1...
- Benzopyrans are selective estrogen receptor beta agonists with novel activity in models of benign prostatic hyperplasia
Bryan H Norman
Discovery Chemistry Research, Bone and Inflammation Research, Lead Optimization Biology, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285, USA
J Med Chem 49:6155-7. 2006
....
- Laparoscopic assisted endorectal pull-through with posterior sagittal approach to the repair of postoperative rectourethral and rectovaginal fistula
Shaotao Tang
Department of Pediatric Surgery, Union Hospital of Huazhong University of Science and Technology, Wuhan 430022, China
Pediatr Surg Int 23:1077-80. 2007
..Posterior sagittal approach provides a direct repair of the fistula and anastomosis...
- Improved production of erythromycin A by expression of a heterologous gene encoding S-adenosylmethionine synthetase
Yong Wang
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China
Appl Microbiol Biotechnol 75:837-42. 2007
..The sporulation process was inhibited, while the SAM-s gene was expressed. The addition of the exogenous SAM also inhibited sporulation and promoted an increase in erythromycin titers...
- Alignment of protein interaction networks by integer quadratic programming
Zhenping Li
Beijing Wuzi University, Beijing, China
Conf Proc IEEE Eng Med Biol Soc 1:5527-30. 2006
..From the viewpoint of graph theory, the proposed method can identify similar subsets between two graphs, which allow gaps for nodes and edges...
- Identification and molecular characterization of novel cry1-type toxin genes from Bacillus thuringiensis K1 isolated in Korea
Ming Shun Li
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Lion Street, Hongshan District, Wuhan 430070, China
J Microbiol Biotechnol 17:15-20. 2007
..Whereas all three novel genes were toxic to Plutella xylostella larvae, only Cry1-1 showed insecticidal activity against Spodoptera exigua larvae...
- Prognostic value of natriuretic peptides in Chagas' disease: a 3-year follow-up investigation
Maria da Consolacao V Moreira
Department of Internal Medicine, Felicio Rocho Hospital, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Cardiology 110:217-25. 2008
..To determine the diagnostic and prognostic value of natriuretic peptides in patients with CD, we measured atrial (ANP) and brain natriuretic peptide (BNP), and compared the findings with other dilated cardiomyopathies (DCM)...
- A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta
Yong Wang
Lilly Research Laboratories, Indianapolis, IN 46285, USA
Proc Natl Acad Sci U S A 103:9908-11. 2006
....
- Transitional cell carcinoma in renal transplant recipients: a single center experience
Xiao bei Li
Kidney Center, Beijing Chaoyang Hospital, Capital University of Medical Sciences, Beijing, China
Int J Urol 15:53-7. 2008
..To present a single center experience in managing transitional cell carcinoma (TCC) in Chinese renal transplant (RTx) recipients...
- Delineation of the functional domains of the extracellular region of YWK-II Protein/APLP2 of sperm membrane
Dazhong Zhuang
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, 5 Dong Dan San, Tiao, Beijing, 100005, China
Front Biosci 11:2371-80. 2006
..The present results suggest that segment 22-308 of YWK-II-763 participates in the binding and fusion of sperm and egg plasma membranes thereby promoting fertilization...
- Axon guidance cue Netrin-1 has dual function in angiogenesis
Yun Yang
Department of Gynecology and Obstetrics, Union Hospital, Huazhong University of Science and Technology, Wuhan, China
Cancer Biol Ther 6:743-8. 2007
..Our study revealed Netrin-1 as a dual-function regulator of angiogenesis and its possible mechanism. The study might be used in anti-angiogenic therapies of cancer in the future...
