Yong Jun Wang

Summary

Publications

  1. ncbi request reprint [Effects of yiqi huayu recipe and its decomposed formulas on apoptosis-related factors of anulus fibrosus cells in rats]
    Quan Zhou
    Spinal Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 3:466-9. 2005
  2. pmc Effects of Qishe Pill, a compound traditional Chinese herbal medicine, on cervical radiculopathy: study protocol for a randomized controlled trial
    Xue Jun Cui
    Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, P, R, China
    Trials 14:322. 2013
  3. doi request reprint Mechanism of resveratrol on the promotion of induced pluripotent stem cells
    Dao Fang Ding
    Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    J Integr Med 11:389-96. 2013
  4. ncbi request reprint [Study of Yiqi Huayu Bushen recipe and its decomposed formulas in regulating gene expressions in degenerated cervical intervertebral discs of rats]
    Yong Jun Wang
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 4:615-9. 2006
  5. ncbi request reprint Cervical intervertebral disc degeneration induced by unbalanced dynamic and static forces: a novel in vivo rat model
    Yong Jun Wang
    Institute of Spine, Shanghai University of Traditional Chinese Medicine Shanghai, China
    Spine (Phila Pa 1976) 31:1532-8. 2006
  6. ncbi request reprint Aging delays the regeneration process following sciatic nerve injury in rats
    Yong Jun Wang
    Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
    J Neurotrauma 24:885-94. 2007
  7. doi request reprint [Establishment of a rat model of cervical syndrome with qi deficiency, blood stasis and kidney deficiency]
    Yong Jun Wang
    Institute of Spine Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 6:1152-8. 2008
  8. ncbi request reprint [Effects of Yiqi Huayu Recipe on gene expression pattern of normal and apoptotic chondrocytes in cervical intervertebral disc in rats]
    Yong Jun Wang
    Spinal Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 3:111-4. 2005
  9. ncbi request reprint [A rabbit model of cervical spondylosis established by stimulation of wind, cold and dampness]
    Yong Jun Wang
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 5:39-44. 2007
  10. ncbi request reprint Gene expression profile of degenerated cervical intervertebral disc tissues in rats
    Yong Jun Wang
    Research Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Chin J Traumatol 7:330-40. 2004

Collaborators

Detail Information

Publications65

  1. ncbi request reprint [Effects of yiqi huayu recipe and its decomposed formulas on apoptosis-related factors of anulus fibrosus cells in rats]
    Quan Zhou
    Spinal Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 3:466-9. 2005
    ..To study the effects of Yiqi Huayu Recipe and its decomposed formulas-medicated sera on expressions of bcl-2, Bax and caspase-8 of apoptotic anulus fibrosus cells in rats...
  2. pmc Effects of Qishe Pill, a compound traditional Chinese herbal medicine, on cervical radiculopathy: study protocol for a randomized controlled trial
    Xue Jun Cui
    Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, P, R, China
    Trials 14:322. 2013
    ..The purpose of the present study is to examine the efficacy and safety of Qishe Pill, a compound traditional Chinese herbal medicine, for neck pain in patients with cervical radiculopathy...
  3. doi request reprint Mechanism of resveratrol on the promotion of induced pluripotent stem cells
    Dao Fang Ding
    Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    J Integr Med 11:389-96. 2013
    ..To investigate the effects of resveratrol (RV) in reprogramming mouse embryonic fibroblasts (MEFs) into induced pluripotent stem cells (iPSCs) and the related mechanism...
  4. ncbi request reprint [Study of Yiqi Huayu Bushen recipe and its decomposed formulas in regulating gene expressions in degenerated cervical intervertebral discs of rats]
    Yong Jun Wang
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 4:615-9. 2006
    ....
  5. ncbi request reprint Cervical intervertebral disc degeneration induced by unbalanced dynamic and static forces: a novel in vivo rat model
    Yong Jun Wang
    Institute of Spine, Shanghai University of Traditional Chinese Medicine Shanghai, China
    Spine (Phila Pa 1976) 31:1532-8. 2006
    ..Establishment of a novel in vivo animal model of cervical spondylosis...
  6. ncbi request reprint Aging delays the regeneration process following sciatic nerve injury in rats
    Yong Jun Wang
    Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
    J Neurotrauma 24:885-94. 2007
    ..Our results suggest that the impaired TSC-axon interaction in aged rats delays the reinnervation process...
  7. doi request reprint [Establishment of a rat model of cervical syndrome with qi deficiency, blood stasis and kidney deficiency]
    Yong Jun Wang
    Institute of Spine Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 6:1152-8. 2008
    ..To establish a rat model of cervical syndrome with qi deficiency, blood stasis and kidney deficiency...
  8. ncbi request reprint [Effects of Yiqi Huayu Recipe on gene expression pattern of normal and apoptotic chondrocytes in cervical intervertebral disc in rats]
    Yong Jun Wang
    Spinal Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 3:111-4. 2005
    ..To study the effects of Yiqi Huayu Recipe on the gene expression pattern in normal and apoptotic chondrocytes in the cervical intervertebral disc of rats...
  9. ncbi request reprint [A rabbit model of cervical spondylosis established by stimulation of wind, cold and dampness]
    Yong Jun Wang
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 5:39-44. 2007
    ..To make an animal model of cervical spondylosis (arthralgia syndrome type) with stimulation of wind, cold, and dampness...
  10. ncbi request reprint Gene expression profile of degenerated cervical intervertebral disc tissues in rats
    Yong Jun Wang
    Research Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Chin J Traumatol 7:330-40. 2004
    ..To analyze the gene expression profile of degenerated cervical intervertebral disc of Sprague Dawley rats on a large scale...
  11. ncbi request reprint [Mechanism of Yiqi Huayu Bushen recipe in treating cervical syndrome in rats with qi deficiency, blood stasis and kidney deficiency]
    Yong Jun Wang
    Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 7:53-8. 2009
    ..To explore the mechanism of Yiqi Huayu Bushen Recipe (YHBR), a compound traditional Chinese herbal medicine, in treating cervical syndrome (CS) with qi deficiency, blood stasis and kidney deficiency in rats...
  12. ncbi request reprint The osteoprotective effect of psoralen in ovariectomy-induced osteoporotic rats via stimulating the osteoblastic differentiation from bone mesenchymal stem cells
    Zhu Yang
    Department of Orthopaedics and Traumatology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Menopause 19:1156-64. 2012
    ..This study was designed to evaluate the osteoprotective effect of PSO in ovariectomy (OVX)-induced rats and to seek possible molecular mechanisms of PSO in bMSCs...
  13. ncbi request reprint Oleanolic acid exerts an osteoprotective effect in ovariectomy-induced osteoporotic rats and stimulates the osteoblastic differentiation of bone mesenchymal stem cells in vitro
    Qin Bian
    Department of Orthopaedics and Traumatology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Menopause 19:225-33. 2012
    ..The aim of the present study was to evaluate the osteoprotective effect of OA in rats with ovariectomy (OVX)-induced osteoporosis and to search for the molecular targets of OA in bone mesenchymal stem cells (bMSCs)...
  14. doi request reprint Prolonged upright posture induces calcified hypertrophy in the cartilage end plate in rat lumbar spine
    Qin Bian
    Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Spine (Phila Pa 1976) 36:2011-20. 2011
    ..Both forelimbs of rats were amputated and these rats were kept in the custom-made cages to keep prolonged and repeated upright posture. Changes of bone were observed in the lumbar vertebrae at three different time points after the surgery...
  15. doi request reprint Prolonged and repeated upright posture promotes bone formation in rat lumbar vertebrae
    Qin Bian
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People s Republic of China
    Spine (Phila Pa 1976) 36:E380-7. 2011
    ..Changes of bone were observed in the lumbar vertebrae at three different time points after the surgery. OBJECTIVE.: To investigate the effect of prolonged and repeated upright posture on bone formation of rat lumbar vertebrae...
  16. doi request reprint [Mechanism of Yiqi Huayu Bushen Recipe in treating cervical syndrome with kidney deficiency in rats]
    Jian chun Jiang
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 6:1280-5. 2008
    ..To research the action mechanism of Yiqi Huayu Bushen Recipe (YHBR), a compound of traditional Chinese herbal medicine, in treating cervical syndrome (CS) with kidney deficiency in rats...
  17. doi request reprint Leg amputation accelerates senescence of rat lumbar intervertebral discs
    Qiu Juan Xing
    Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai, People s Republic of China
    Spine (Phila Pa 1976) 35:E1253-61. 2010
    ..Several senescence biomarkers were observed to investigate cell senescence in degenerative intervertebral lumbar discs of foreleg-amputated rats...
  18. ncbi request reprint Herb formula "Fufangqishe-Pill" prevents upright posture-induced intervertebral disc degeneration at the lumbar in rats
    Qian Qian Liang
    Department of Orthopaedics and Traumatology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, China
    J Pharmacol Sci 113:23-31. 2010
    ..These results suggest that FFQSP prevents lumbar IVD degeneration induced by upright posture. FFQSP is a promising medicine for lumbar IVD degeneration disease...
  19. doi request reprint Prolonged upright posture induces degenerative changes in intervertebral discs of rat cervical spine
    Qian Qian Liang
    Department of Orthopaedics and Traumatology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People s Republic of China
    Spine (Phila Pa 1976) 36:E14-9. 2011
    ..An in vivo study of the cervical intervertebral discs (IVDs) response to upright posture was performed using an amputated bipedal rat model...
  20. doi request reprint [Establishment of a rat model of cervical syndrome with kidney deficiency]
    Jian chun Jiang
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 6:1034-9. 2008
    ..To establish a rat model of cervical syndrome (CS) with kidney deficiency...
  21. ncbi request reprint Inhibitory effect of YQHYRJ recipe on osteoblast differentiation induced by BMP-2 in fibroblasts from posterior longitudinal ligament of mice
    Qin Bian
    Department of Orthopaedics and Traumatology, Longhua Hospital, Shanghai, China
    Pharmazie 66:784-90. 2011
    ..These results suggested YQHYRJ to be effective in inhibiting osteoblast differentiation induced by BMP-2 in fibroblasts from posterior longitudinal ligament. YQHYRJ might be a promising medicine for preventing OPLL disease...
  22. ncbi request reprint The osteogenetic effect of astragaloside IV with centrifugating pressure on the OCT-1 cells
    Qin Bian
    Department of Orthopaedics and Traumatology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Pharmazie 66:63-8. 2011
    ..We concluded that ASI would promote osteogenesis when cells of preosteoblast OCT-1 were subjected to proper centrifugating pressure and a pertinent period of time...
  23. pmc The expression of osteoprotegerin is required for maintaining the intervertebral disc endplate of aged mice
    Qian Qian Liang
    Department of Orthopaedics and Traumatology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, PR China
    Bone 48:1362-9. 2011
    ..Here we assessed the phenotype change of IVD in OPG(-/-) mice...
  24. ncbi request reprint Prolonged upright posture induces degenerative changes in intervertebral discs in rat lumbar spine
    Qian Qian Liang
    Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai, People s Republic of China
    Spine (Phila Pa 1976) 33:2052-8. 2008
    ..Both forelimbs of rats were amputated, and these rats were kept in the custom-made cages that kept the rats in prolonged upright posture. Pathologic changes were observed in the lumbar spine at different time points after the surgery...
  25. pmc Muscone protects vertebral end-plate degeneration by antiinflammatory property
    Qian Qian Liang
    Institute of Spine, 725 Wan Ping South Road, Shanghai, 200032, China
    Clin Orthop Relat Res 468:1600-10. 2010
    ..Our findings suggest muscone is a promising agent for treating intervertebral disc degeneration through its antiinflammatory effects...
  26. doi request reprint A continuous observation of the degenerative process in the intervertebral disc of Smad3 gene knock-out mice
    Chen Guang Li
    Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai, People s Republic of China
    Spine (Phila Pa 1976) 34:1363-9. 2009
    ..Pathologic changes were observed in the spine of small mother against decapentaplegic (Smad) 3 mice at different time points...
  27. pmc Chondrocyte-specific inhibition of β-catenin signaling leads to dysplasia of the caudal vertebrae in mice
    Bing Shu
    Spine Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China Department of Biochemistry, Rush University Medical Center, Chicago, IL and Department of Physical Medicine and Rehabilitation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
    Spine (Phila Pa 1976) 38:2079-84. 2013
    ..To inhibit β-catenin specifically signaling in chondrocytes Col2-ICAT transgenic mice were generated. Anomalies in caudal vertebrae were detected during embryonic and postnatal stages of Col2-ICAT transgenic mice...
  28. ncbi request reprint [Regulation effects of Gegen Recipe and Guizhi Recipe on expression of IL-1beta, iNOS, TNFalpha, TGFbeta mRNA in degenerated cervical intervertebral disk in rabbits]
    Yong Jun Wang
    Institute of Spinal Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 1:273-6. 2003
    ..To study the effects of Gegen Recipe and Guizhi Recipe regulating the expression of IL-1beta, iNOS, TNFalpha and TGFbeta mRNA in degenerated intervertebral disk caused by stimulation of wind, cold and damp...
  29. ncbi request reprint [Effect of Yiqi Huayu Recipe on regeneration process after L5 nerve root compression in rats]
    Chong Jian Zhou
    Institute of Spinal Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 1:277-80. 2003
    ..To study the effect of Yiqi Huayu Recipe on neurons in neuromuscular junction after L5 nerve root compression in rats...
  30. ncbi request reprint [Study on Yiqi Huayu Bushen Recipe and its disassembled recipes in regulating mRNA expression of collagens and metabolic enzymes in extracellular matrix of cervical disc]
    Qi Shi
    Institute of Spinal Disease, Longhua Hospital, Shanghai University of TCM, Shanghai
    Zhongguo Zhong Xi Yi Jie He Za Zhi 27:142-6. 2007
    ....
  31. ncbi request reprint [An in vitro natural degeneration model of chondrocytes derived from endplate of intervertebral discs of rats]
    Ji Xiang Shi
    Institute of Spinal Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 4:293-7. 2006
    ..To set up a natural degeneration model of chondrocytes derived from endplate of intervertebral discs of rats in order to offer an appropriate carrier for the study on mechanism of intervertebral disc degeneration...
  32. doi request reprint Changes of cervical dorsal root ganglia induced by compression injury and decompression procedure: a novel rat model of cervical radiculoneuropathy
    Zhan Ying Tang
    Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai, P R China
    J Neurotrauma 26:289-95. 2009
    ..We conclude that such a model provides a tool to study the pathogenesis and treatment of cervical radiculoneuropathy...
  33. ncbi request reprint [Effects of Yiqi Huayu Recipe on neural cell adhesion molecule in rats with lumbar nerve root compression]
    Chong Jian Zhou
    Institute of Spinal Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 4:175-80. 2006
    ..To study the effects of Yiqi Huayu Recipe on neural cell adhesion molecule (N-CAM) in neuromuscular junctions during nerve regeneration in rats with lumbar nerve root compression...
  34. ncbi request reprint [Effects of Qishe Pill on vertebral hyperostosis induced by upright posture in rats]
    Qin Bian
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 8:173-80. 2010
    ..To observe the effects of Qishe Pill, a compound traditional Chinese herbal medicine, on lumbar vertebral bone formation induced by long-time upright posture in rats and to investigate the potential mechanism...
  35. ncbi request reprint [Effect of Yiqi Huayu recipe on peanut agglutinin-binding molecules and Schwann's cells in rats after lumbar nerve root compression]
    Chong Jian Zhou
    Institute of Spinal Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 2:353-7. 2004
    ..To study the effect of Yiqi Huayu Recipe on peanut agglutinin-binding molecules (PNA-BMs) and Schwann's cells (Sc) of the neuromuscular junction after L5 nerve root compression in rats...
  36. pmc Classic yin and yang tonic formula for osteopenia: study protocol for a randomized controlled trial
    Feng Yang
    Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, PR China
    Trials 12:187. 2011
    ..The purpose of this study is to evaluate the effect on BMD and safety of the Classic Yin and Yang Tonic Formula for treatment of osteopenia and to investigate the mechanism by which this efficacy is achieved...
  37. ncbi request reprint Insulin-like growth factor-1 treatment prevents anti-Fas antibody-induced apoptosis in endplate chondrocytes
    Yong Jun Wang
    Institute of Spine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Spine (Phila Pa 1976) 31:736-41. 2006
    ..In vitro investigation of vertebral endplate chondrocyte apoptosis...
  38. pmc Distribution and alteration of lymphatic vessels in knee joints of normal and osteoarthritic mice
    Jixiang Shi
    PuTuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China University of Rochester Medical Center, Rochester, New York
    Arthritis Rheumatol 66:657-66. 2014
    ..To investigate the distribution and alteration of lymphatic vessels and draining function in knee joints of normal and osteoarthritic mice...
  39. ncbi request reprint [Effects of Yiqi Huayu Decoction on brain-derived neurotrophic factor expression in rats with lumbar nerve root injury]
    Bing Shu
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 8:280-6. 2010
    ..To observe the effects of Yiqi Huayu Decoction, a compound traditional Chinese herbal medicine, on brain-derived neurotrophic factor (BDNF) expression in lumbar nerve root and soleus of rats after lumbar nerve root compression injury...
  40. ncbi request reprint Different molecular targets of Icariin on bMSCs in CORT and OVX -rats
    Qin Bian
    Department of Orthopaedics and Traumatology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, No 725 South Wan ping Road, Shanghai, China
    Front Biosci (Elite Ed) 4:1224-36. 2012
    ..However, the Notch signaling pathway was common in both models, and should be paid close attention to for further study...
  41. ncbi request reprint [Effects of Chinese herbal medicine Yiqi Huayu Bushen Recipe on expressions of aggrecan and type X collagen mRNAs in cells from degenerated human intervertebral discs]
    Ju Bao Li
    Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Zhong Xi Yi Jie He Xue Bao 9:1138-44. 2011
    ....
  42. ncbi request reprint [Effects of Chinese herbal medicine Yiqi Huayu Recipe on apoptosis of dorsal root ganglion neurons and expression of caspase-3 in rats with lumbar nerve root compression]
    Le Qin Xu
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, China
    Zhong Xi Yi Jie He Xue Bao 8:1174-9. 2010
    ..To observe the effects of Yiqi Huayu Recipe, a Chinese compound herbal medicine, on apoptosis of dorsal root ganglion (DRG) neurons and expression of caspase-3 in rats after lumbar nerve root compression injury...
  43. ncbi request reprint [Preventive and therapeutic effects of Yiqi Huayu Recipe on degeneration of articular cartilage in rats with osteoarthritis]
    Wei Hou
    Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 7:163-8. 2009
    ..To study the efficacy and possible mechanism of Yiqi Huayu Recipe (YQHYR), a compound traditional Chinese herbal medicine, in preventing and treating degeneration of the articular cartilage in rats with osteoarthritis (OA)...
  44. ncbi request reprint [Effects of Yiqi Huayu prescription on knee cartilage degeneration in HIF-1alpha gene knockout mice]
    Jing Wang
    Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhongguo Gu Shang 26:486-92. 2013
    ....
  45. pmc Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice
    Quan Zhou
    Longhua Hospital and Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Arthritis Rheum 63:2318-28. 2011
    ....
  46. pmc Osthole stimulates osteoblast differentiation and bone formation by activation of beta-catenin-BMP signaling
    De Zhi Tang
    Spine Research Institute, Shanghai University of Traditional Chinese Medicine, Shanghai, People s Republic of China
    J Bone Miner Res 25:1234-45. 2010
    ..Our findings demonstrate that Osthole could be a potential anabolic agent to stimulate bone formation and prevent estrogen deficiency-induced bone loss...
  47. pmc Chinese herbal medicine for osteoporosis: a systematic review of randomized controlled trails
    Zhi Qian Wang
    Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 South Wanping Road, Shanghai 200032, China
    Evid Based Complement Alternat Med 2013:356260. 2013
    ..03, 95% CI: -0.01-0.08; femoral: WMD = 0.01, 95% CI: -0.01-0.02). Conclusions. Our results demonstrated that Chinese herb significantly increased lumbar spine BMD as compared to the placebo or other standard anti-osteoporotic drugs...
  48. ncbi request reprint [Professor Shi Qi's experience of applying herbal paste for treating chronic musculoskeletal conditions]
    Xiao Feng Li
    Institute of Spine Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 10:701-6. 2012
    ....
  49. pmc Psoralen stimulates osteoblast differentiation through activation of BMP signaling
    De Zhi Tang
    Spine Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, PR China
    Biochem Biophys Res Commun 405:256-61. 2011
    ....
  50. doi request reprint Triptolide inhibits extracellular matrix protein synthesis by suppressing the Smad2 but not the MAPK pathway in TGF-beta1-stimulated NRK-49F cells
    Bin Zhu
    Department of Nephrology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou Guangxing Hospital, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China
    Nephrol Dial Transplant 25:3180-91. 2010
    ..Triptolide has been used for treating various autoimmune diseases. However, it remains unclear whether triptolide exerts effects on extracellular matrix (ECM) synthesis, which plays an important role in renal fibrosis...
  51. ncbi request reprint [History and development of spinology]
    Qi Shi
    Institute of Spinal Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 1:304-8, 320. 2003
    ..In this article, the history, development, foundations and research progress of non-surgical operation of spinal diseases and the developing tendency of modern spinology are introduced...
  52. ncbi request reprint Osteoarthritis: genetic factors, animal models, mechanisms, and therapies
    Qin Bian
    Department of Orthopedics and Traumatology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, No 725 South Wan ping Road, Shanghai, China
    Front Biosci (Elite Ed) 4:74-100. 2012
    ..To systematically understand OA, this review summarizes OA disease genes, mouse models of human disease experimental mouse models, mechanisms of OA pathogenesis, and current OA therapies...
  53. ncbi request reprint [An experimental study on the influence of radix astragali on the ressorption of ruptured disc herniation]
    Hong Jiang
    The Institute of Spinal Disease, the Shanghai University of TCM, 201203, Shanghai, China
    Zhongguo Gu Shang 22:205-7. 2009
    ..To investigate the possible mechanism of immune response in the resorption of the ruptured intervertebral disc herniation, and the possible mechanism of radix astragali on the resorption of the ruptured disc herniation...
  54. ncbi request reprint [Progress in research on focal adhesion kinase signal transduction and cross-talk]
    Qin Bian
    Research Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 3:495-7. 2005
  55. ncbi request reprint [The relationship between hypoxia-inducible factor-1α and cartilage degeneration in osteoarthritis: a review]
    Fang Fang Dong
    Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Zhong Xi Yi Jie He Xue Bao 10:13-8. 2012
    ..In this paper, the authors review the situation of the correlation between HIF-1α and osteoarthritis cartilage degeneration examined in recent years...
  56. ncbi request reprint Chinese herbal medicines for treating skin and soft-tissue infections
    Yun Fei Wang
    Department of Traditional Chinese Surgery, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 725 South Wan Ping Road, Shanghai, Shanghai, China, 200032
    Cochrane Database Syst Rev 7:CD010619. 2014
    ..Therefore there is a need to review the current clinical evidence systematically to inform current practice and guide future studies on Chinese herbal medicines for SSTIs...
  57. pmc Near-infrared lymphatic imaging demonstrates the dynamics of lymph flow and lymphangiogenesis during the acute versus chronic phases of arthritis in mice
    Quan Zhou
    Longhua Hospital and Shanghai University of Traditional Chinese Medicine, Shanghai, China
    Arthritis Rheum 62:1881-9. 2010
    ..To develop an in vivo imaging method to assess lymphatic draining function in the K/BxN mouse model of inflammatory arthritis...
  58. pmc Inhibition of beta-catenin signaling in articular chondrocytes results in articular cartilage destruction
    Mei Zhu
    University of Rochester, Rochester, New York 14642, USA
    Arthritis Rheum 58:2053-64. 2008
    ..To determine the role of beta-catenin signaling in articular chondrocyte function, we generated Col2a1-ICAT-transgenic mice to inhibit beta-catenin signaling in chondrocytes...
  59. ncbi request reprint [Anti-hypertensive treatment for prevention and control of stroke]
    Yong Jun Wang
    Zhonghua Nei Ke Za Zhi 43:726-7. 2004
  60. ncbi request reprint Effect of phorbol esters on activity of Ha-ras gene promoter in HeLa cells
    Wei Zhang
    The Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education, College of Life Science, Beijing Normal University, Beijing 100875, China
    Acta Pharmacol Sin 23:300-4. 2002
    ..To study the role of phorbol esters (PMA) in the activity of promoter of Ha-ras in HeLa cells...
  61. pmc Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation
    Run Shen
    Department of Orthopaedics and Department of Pathology, Center for Musculoskeletal Research, University of Rochester, School of Medicine, Rochester, New York 14642, USA
    J Biol Chem 281:3569-76. 2006
    ..Smurf1-induced Runx2 degradation serves as a negative regulatory mechanism for the BMP-Smad-Runx2 signaling pathway...
  62. ncbi request reprint [Mapping QTLs of soybean root weight with RIL population NJRIKY]
    Hong Lin Wang
    Soybean Research Institute of Nanjing Agricultural University, National Center for Soybean Improvement, and National Key Laboratory for Crop Genetics and Germplasm Enhancement, Nanjing 210095, China
    Yi Chuan 26:333-6. 2004
    ..Their LOD values were 10.34,4.01 and 3.15, respectively. The QTLs of the root weight explained 26.3%,9.2% and 6.8% of the total variation, and their additive effects were -0.514,-0.303 and -0.260, respectively...
  63. ncbi request reprint [Shortening the distance between evidence-based medicine and practice in the prevention of cerebrovascular diseases]
    Yong Jun Wang
    Department of Neurology, Beijing Tianton Hospital Affiliated to Capital University of Medical Sciences, Beijing 100050, China
    Zhonghua Yu Fang Yi Xue Za Zhi 37:79-80. 2003
  64. ncbi request reprint [The neuroprotection of resveratrol in the experimental cerebral ischemia]
    Yong Jun Wang
    Department of Neurology, Tiantan Hospital, Capital University of Medical Sciences, Beijing 100050, China
    Zhonghua Yi Xue Za Zhi 83:534-6. 2003
    ..To study the effect of resveratrol on cerebral infarct volume, cerebral edema as well as the expression of nuclear fac for (NF-kappaB) p65 in the experimental permanent middle cerebral artery occlusion...
  65. ncbi request reprint Effects of Shuanghuangbu on the total protein content and ultrastructure in cultured human periodontal ligament cells
    Yan Zhi Xu
    Department of Stomatology, The Fourth Hospital, Hebei Medical University, Shijiazhuang 050011, China
    Chin Med J (Engl) 117:1693-6. 2004
    ..This study was conducted to observe the effects of Shuanghuangbu, a mixture of medicinal herbs, on the total protein content and the ultrastructure of human periodontal ligament cells...