Yi Wang

Summary

Publications

  1. ncbi request reprint Stem cell transplantation: a promising therapy for Parkinson's disease
    Yi Wang
    Institute of Health Sciences, Shanghai Institutes for Biological Sciences of Chinese Academy of Science and Shanghai Jiao Tong University School of Medicine, 225 South Chongqing Road, Shanghai 200025, China
    J Neuroimmune Pharmacol 2:243-50. 2007
  2. doi request reprint miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression
    Dehua Yang
    Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    J Cell Sci 125:1673-82. 2012
  3. doi request reprint Mifepristone-inducible caspase-1 expression in mouse embryonic stem cells eliminates tumor formation but spares differentiated cells in vitro and in vivo
    Yi Wang
    Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine and Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    Stem Cells 30:169-79. 2012
  4. ncbi request reprint Stability of entomopathogenic bacteria, Xenorhabdus nematophila and Photorhabdus luminescens, during in vitro culture
    Yi Wang
    Department of Entomology, Rutgers University, New Brunswick, NJ 08901 8524, USA
    J Ind Microbiol Biotechnol 34:73-81. 2007
  5. ncbi request reprint [Target-controlled infusion of remifentanil and propofol during operation with suspension laryngoscopy]
    Min Yan
    Departmentof Anesthesiology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:557-61, 565. 2005
  6. ncbi request reprint [Update of the researches on sperm proteome]
    Yi Wang
    First School of Clinical Medicine, Nanjing Medical University, Key Laboratory of Reproductive Medicine of Jiangsu Province, Nanjing, Jiangsu 210029, China
    Zhonghua Nan Ke Xue 13:250-4. 2007
  7. doi request reprint Heparanase, a key target for gene therapy against human malignancies
    Youlei Zhang
    Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, 200438, China
    ScientificWorldJournal 7:1965-7. 2007
  8. ncbi request reprint [Experimental study on the osseointegration of nanophase hydroxyapatite biograde-coated implants]
    Yi Wang
    Department of Orthopaedic, Ruijn Hospital, Shanghai Second Medical University, Shanghai 200025, China
    Zhonghua Wai Ke Za Zhi 43:1336-9. 2005
  9. ncbi request reprint Anti-angiogenesis effects of meisoindigo on chronic myelogenous leukemia in vitro
    Zhijian Xiao
    State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, 288 Nanjing Road, Tianjin 300020, China
    Leuk Res 30:54-9. 2006
  10. doi request reprint Periodic oscillation in delayed gene networks with SUM regulatory logic and small perturbations
    Yi Wang
    Shanghai University College of Science, Shanghai University, Shanghai, China
    Math Biosci 220:34-44. 2009

Collaborators

Detail Information

Publications73

  1. ncbi request reprint Stem cell transplantation: a promising therapy for Parkinson's disease
    Yi Wang
    Institute of Health Sciences, Shanghai Institutes for Biological Sciences of Chinese Academy of Science and Shanghai Jiao Tong University School of Medicine, 225 South Chongqing Road, Shanghai 200025, China
    J Neuroimmune Pharmacol 2:243-50. 2007
    ..Future stem cell research should focus not only on ameliorating the symptoms of Parkinson's disease but also on neuroprotection or neurorescue that can favorably modify the natural course and slow the progression of the disease...
  2. doi request reprint miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression
    Dehua Yang
    Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    J Cell Sci 125:1673-82. 2012
    ..Collectively, our data provide the first evidence that miR-132 is an important molecule regulating ES cell differentiation into dopamine neurons by directly targeting Nurr1 gene expression...
  3. doi request reprint Mifepristone-inducible caspase-1 expression in mouse embryonic stem cells eliminates tumor formation but spares differentiated cells in vitro and in vivo
    Yi Wang
    Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine and Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    Stem Cells 30:169-79. 2012
    ..These results suggest that this novel ESC-based therapy can be used in Parkinson's disease and other related disorders without the risk of tumor formation...
  4. ncbi request reprint Stability of entomopathogenic bacteria, Xenorhabdus nematophila and Photorhabdus luminescens, during in vitro culture
    Yi Wang
    Department of Entomology, Rutgers University, New Brunswick, NJ 08901 8524, USA
    J Ind Microbiol Biotechnol 34:73-81. 2007
    ..In vitro producers of the P. luminescens/H. bacteriophora complex must weigh the need for superior bacterial yield against the need to preserve traits important for biological control...
  5. ncbi request reprint [Target-controlled infusion of remifentanil and propofol during operation with suspension laryngoscopy]
    Min Yan
    Departmentof Anesthesiology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:557-61, 565. 2005
    ..To evaluate target-controlled infusion (TCI) of remifentail-propofol and the balanced anesthesia of fentanyl-isoflurane during the operation with suspension laryngscope...
  6. ncbi request reprint [Update of the researches on sperm proteome]
    Yi Wang
    First School of Clinical Medicine, Nanjing Medical University, Key Laboratory of Reproductive Medicine of Jiangsu Province, Nanjing, Jiangsu 210029, China
    Zhonghua Nan Ke Xue 13:250-4. 2007
    ....
  7. doi request reprint Heparanase, a key target for gene therapy against human malignancies
    Youlei Zhang
    Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, 200438, China
    ScientificWorldJournal 7:1965-7. 2007
  8. ncbi request reprint [Experimental study on the osseointegration of nanophase hydroxyapatite biograde-coated implants]
    Yi Wang
    Department of Orthopaedic, Ruijn Hospital, Shanghai Second Medical University, Shanghai 200025, China
    Zhonghua Wai Ke Za Zhi 43:1336-9. 2005
    ..To study the osseointegration of the nanophase hydroxyapatite biograde-coated implants and host bone...
  9. ncbi request reprint Anti-angiogenesis effects of meisoindigo on chronic myelogenous leukemia in vitro
    Zhijian Xiao
    State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, 288 Nanjing Road, Tianjin 300020, China
    Leuk Res 30:54-9. 2006
    ..This effect may contribute to the anti-leukemic effect of this drug...
  10. doi request reprint Periodic oscillation in delayed gene networks with SUM regulatory logic and small perturbations
    Yi Wang
    Shanghai University College of Science, Shanghai University, Shanghai, China
    Math Biosci 220:34-44. 2009
    ....
  11. ncbi request reprint [Advances of clinical studies on acupuncture treatment of depression]
    Xu Guo
    Guang an Men Hospital of China Academy of Chinese Medical Sciences, Beijing 100053, China
    Zhen Ci Yan Jiu 33:416-9. 2008
    ..Moreover, the authors also make a discussion and a prospect on the treatment of depression and put forward some suggestions for clinical researches in the coming days...
  12. pmc Llandovery sporomorphs and graptolites from the Manbo Formation, the Mojiang County, Yunnan, China
    Yi Wang
    LPS, Nanjing Institute of Geology and Palaeontology, CAS, Nanjing 210008, People s Republic of China
    Proc Biol Sci 277:267-75. 2010
    ..They were also closely related with Gondwanaland in the Llandovery...
  13. ncbi request reprint [Analysis on the current situation of establishing control group in clinical studies of acupuncture and moxibustion for treatment of periarthritis of shoulder]
    Wei ma Peng
    Guang anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
    Zhongguo Zhen Jiu 27:453-7. 2007
    ..To probe into the current situation and problems of establishing control group in clinical studies of acupuncture and moxibustion for treatment of periarthritis of shoulder at home...
  14. pmc Hemorrhagic hepatic cysts mimicking biliary cystadenoma
    You Lei Zhang
    Eastern Hepatobiliary Surgery Hospital, The Second Military Medical University, Shanghai 200438, China
    World J Gastroenterol 15:4601-3. 2009
    ..Cystectomy and left hepatectomy were performed for the two patients, respectively. Both patients recovered quickly after their operations and showed no recurrence...
  15. ncbi request reprint [Regulation of GacA on two phz gene clusters and quorum sensing in Pseudomonas sp. M18]
    Mingqi Shi
    College of Life Science, Shanghai Jiaotong University, Shanghai 200240, China
    Wei Sheng Wu Xue Bao 49:1306-16. 2009
    ..The regulatory function investigation of two component system gacS/gacA on two phz gene clusters expression and quorum sensing system (QS) in Pseudomonas. sp. M18...
  16. ncbi request reprint EphA1 receptor silencing by small interfering RNA has antiangiogenic and antitumor efficacy in hepatocellular carcinoma
    Gang Chen
    Department of Hepatobiliary Surgery, The First Affiliated Hospital, Wenzhou Medical College, Wenzhou, PR China
    Oncol Rep 23:563-70. 2010
    ....
  17. ncbi request reprint Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis
    XiaoJie Zhang
    The Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Autophagy 7:412-25. 2011
    ....
  18. ncbi request reprint Rig-I-/- mice develop colitis associated with downregulation of G alpha i2
    Yi Wang
    Department of Medical Genetics, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    Cell Res 17:858-68. 2007
    ..The development of colitis may be, at least in part, associated with downregulation of G alpha i2 and disturbed T-cell homeostasis...
  19. ncbi request reprint [Malaria situation in the People's Republic Of China in 2007]
    Shui sen Zhou
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 26:401-3. 2008
    ..In addition, provinces not covered by the Global Fund Program such as Guizhou, Zhejiang, Guangdong were confronted an increasing disease burden by malaria, which may become a new challenge to the National Malaria Control Program...
  20. ncbi request reprint Inhibition of angiogenesis by a novel small peptide consisting of the active fragments of platelet factor-4 and vasostatin
    Xiaokun Li
    School of Pharmaceutical Science, Wenzhou Medical College, Wenzhou 325035, PR China
    Cancer Lett 256:29-32. 2007
    ..The data suggest that making a single recombinant peptide containing the active fragments of multiple angiogenesis inhibitors is a promising approach to developing a better anti-angiogenetic therapy...
  21. ncbi request reprint Downregulating the expression of heparanase inhibits the invasion, angiogenesis and metastasis of human hepatocellular carcinoma
    Youlei Zhang
    Eastern Hepatobiliary Surgery Hospital, The Second Military Medical University, Shanghai 200433, China
    Biochem Biophys Res Commun 358:124-9. 2007
    ..Our results suggest that genetic downregulation of the expression of heparanase may serve as an efficient cancer therapeutic for human HCC...
  22. doi request reprint Human umbilical cord blood-derived non-hematopoietic stem cells suppress lymphocyte proliferation and CD4, CD8 expression
    Fengqing Ji
    The Department of Histology and Embryology, Beijing, China
    J Neuroimmunol 197:99-109. 2008
    ..The results indicate that both undifferentiated and differentiated CB-nHSCs all have weak immunogenicity...
  23. ncbi request reprint Adenovirus-mediated gene therapy with an antiangiogenic fragment of thrombospondin-1 inhibits human leukemia xenograft growth in nude mice
    Peng Liu
    State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, 288 Nanjing Road, Tianjin 300020, PR China
    Leuk Res 27:701-8. 2003
    ..TSP-1(f)-treated tumors compared to the controls. These data support the use of in vivo gene delivery approach to produce antiangiogenic fragment of TSP-1 for leukemia therapy...
  24. ncbi request reprint [Angiogenesis and regulatory factors in rats with BPH induced by testosterone]
    Ji chun Shao
    Department of Urology, Affiliated Hospital of Chengdu University of TCM, Chengdu, Sichuan 610072, China
    Zhonghua Nan Ke Xue 11:413-8. 2005
    ..To study angiogenesis and regulatory factors in the proliferated prostatic tissues of Sprague Dawley (SD) rats with BPH induced by testosterone...
  25. ncbi request reprint [Efficient generation of recombinant adenoviruses expressing antiangiogenic fragment of human thrombospondin1]
    Peng Liu
    State Key Laboratory of Experimental Hematology, Institute of Hematology, Blood Diseases Hospital, CAMS, PUMC, Tianjin 300020, China
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao 25:312-5. 2003
    ..To construct recombinant adenoviruses expressing antiangiogenic fragment of human thrombospondin1 (TSP1f)...
  26. pmc Signaling networks assembled by oncogenic EGFR and c-Met
    Ailan Guo
    Cell Signaling Technology Inc, 3 Trask Lane, Danvers, MA 01923, USA
    Proc Natl Acad Sci U S A 105:692-7. 2008
    ..Comparison of the signaling networks in EGFR and c-Met-dependent cells identify a "core network" of approximately 50 proteins that participate in pathways mediating drug response...
  27. ncbi request reprint Three-dimensional cine imaging using variable-density spiral trajectories and SSFP with application to coronary artery angiography
    Bryan Kressler
    Department of Biomedical Engineering, Cornell University, Ithaca, New York, USA, and Department of Radiology, Chinese PLA General Hospital, Beijing, China
    Magn Reson Med 58:535-43. 2007
    ..The technique was evaluated on healthy volunteers (n=8), yielding images with 102 ms temporal resolution and 1.35 mm in-plane resolution, and reasonable visualization of the left and right coronary arteries was achieved...
  28. ncbi request reprint [Effect of acupuncture serum on the number of osteclast cultured in vitro]
    Ying xia Zhao
    College of Basic Medicine, Shanghai University of TCM, China
    Zhongguo Zhen Jiu 27:521-4. 2007
    ..To observe effects of acupuncture serum of ovariectomized rats on the number of in vitro cultural osteoclast of newborn rats...
  29. ncbi request reprint Diagnostic value of mucins (MUC1, MUC2 and MUC5AC) expression profile in endoscopic ultrasound-guided fine-needle aspiration specimens of the pancreas
    Yi Wang
    Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
    Int J Cancer 121:2716-22. 2007
    ..Our observations suggest the mucins expression profile in EUS-FNA specimens has higher value for the diagnosis of pancreatic cancer and mucinous neoplasms...
  30. pmc Electroacupuncture activates corticotrophin-releasing hormone-containing neurons in the paraventricular nucleus of the hypothalammus to alleviate edema in a rat model of inflammation
    Aihui Li
    Center for Integrative Medicine, School of Medicine, University of Maryland, Baltimore, MD 21201, USA
    BMC Complement Altern Med 8:20. 2008
    ..This study investigated the mechanisms of EA anti-inflammation, using a rat model of complete Freund's adjuvant (CFA)-induced hind paw inflammation and hyperalgesia...
  31. pmc Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of inflammation
    Aihui Li
    Center for Integrative Medicine, School of Medicine, University of Maryland, Baltimore, MD 21201, USA
    BMC Complement Altern Med 7:27. 2007
    ..However, the mechanisms are not clear. The present study investigated the biochemical mechanisms of EA anti-inflammation in a rat model...
  32. ncbi request reprint Effect of resistin on vascular endothelium secretion dysfunction in rats
    Yan Li
    Department of Pediatrics, Shandong Provincial Hospital, Shandong University, Jinan, People s Republic of China
    Endothelium 14:207-14. 2007
    ..The effect of resistin on PI3K signaling pathway might contribute to the development of endothelial secretion dysfunction in young rats...
  33. ncbi request reprint [Development of a K562 multidrug-resistant cell line and study on proteins with altered expression]
    Yi Wang
    Cancer Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
    Shi Yan Sheng Wu Xue Bao 36:342-6. 2003
    ..These proteins are involved in cell cycling and transcription regulation, whose expression alterations may contribute to the multidrug resistant phenotype of K562/ADR cells...
  34. doi request reprint A microchip-based flow injection-amperometry system with mercaptopropionic acid modified electroless gold microelectrode for the selective determination of dopamine
    Yi Wang
    Institute of Micro analytical Systems, Department of Chemistry, Zhejiang University, Zijin gang Campus, Hangzhou 310058, China
    Anal Chim Acta 625:180-7. 2008
    ..A RSD of 0.9% for peak heights was observed for 19 runs of a 100 micromol L(-1) DA solution. Interference-free determination of DA could be conducted if the concentration ratio of AA-DA was no more than 10...
  35. ncbi request reprint The roles of MMP-2/TIMP-2 in extracellular matrix remodelling in the hearts of STZ-induced diabetic rats
    Qian Li
    Department of Pediatrics, Shandong Provincial Hospital, Shandong University, Jinan, China
    Acta Cardiol 62:485-91. 2007
    ....
  36. ncbi request reprint Quorum sensing signaling molecules involved in the production of violacein by Pseudoalteromonas
    Yi Wang
    Department of Environmental Systems Engineering, Kochi University of Technology, Tosayamada, Kami, Kochi, Japan
    Biosci Biotechnol Biochem 72:1958-61. 2008
    ..The former but not the latter induced the production of violacein in strain 520P1. We conclude that N-(3-oxooctanoyl)-homoserine lactone is a signaling molecule involved in the production of violacein...
  37. doi request reprint Alpha-crystallin protected axons from optic nerve degeneration after crushing in rats
    Xi Ying
    Department of Ophthalmology, Southwest Hospital, Third Military Medical University, Chongqing, China
    J Mol Neurosci 35:253-8. 2008
    ..This effect declined by 4 weeks after injection but survival of axons remained greater than controls. These findings indicate that alpha-crystallin plays a key role in protecting axons after optic nerve injury...
  38. doi request reprint Expanded donor natural killer cell and IL-2, IL-15 treatment efficacy in allogeneic hematopoietic stem cell transplantation
    Guanghua Chen
    Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, First Affiliated Hospital of Soochow University, Suzhou, China
    Eur J Haematol 81:226-35. 2008
    ..The findings may have important significance for complication prevention in clinical allo-HSCT...
  39. doi request reprint Plasma and urinary tanshinol from Salvia miltiorrhiza (Danshen) can be used as pharmacokinetic markers for cardiotonic pills, a cardiovascular herbal medicine
    Tong Lu
    Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
    Drug Metab Dispos 36:1578-86. 2008
    ..In conclusion, plasma and urinary TSL are promising PK markers for cardiotonic pills at the tested dose levels...
  40. ncbi request reprint Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase
    Mei Leng
    Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Cell Cycle 7:1480-9. 2008
    ..Our study provides a mechanism for targeting Plk1 to chromosome arms and suggests that the PICH ATPase activity is important for the regulation of mitotic chromosome architecture...
  41. ncbi request reprint Optical antisense imaging of tumor with fluorescent DNA duplexes
    Xinrong Liu
    Depatment of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Bioconjug Chem 18:1905-11. 2007
    ..This proof of concept investigation of optical antisense targeting therefore suggests that further studies including optimization of this approach are appropriate...
  42. ncbi request reprint Distribution and expression of RhoA in rat retina after optic nerve injury
    Yan Hua Wang
    Department of Ophthalmology, Southwest Hospital, Third Military Medical University, Chongqing, China
    Ophthalmic Res 39:174-8. 2007
    ..RhoA is a small guanosine triphosphatase which participates in signaling pathways of axonal repellents or inhibitors. However, the distribution and expression of RhoA in the rat retina after optic nerve injury has not been elucidated yet...
  43. ncbi request reprint Silencing of LMP1 induces cell cycle arrest and enhances chemosensitivity through inhibition of AKT signaling pathway in EBV-positive nasopharyngeal carcinoma cells
    Yu Ping Mei
    State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat Sen University, Guangzhou, China
    Cell Cycle 6:1379-85. 2007
    ..It is reported for the first time that AKT signaling pathway was directly involved in the effects induced by siRNA targeting LMP1. Our findings confirm LMP1 as a rational therapeutic target in NPC...
  44. ncbi request reprint [Expression of wild type and variant estrogen receptors in human hepatocellular carcinoma]
    Bao Cai Xing
    Department of Surgery, Peking University School of Oncology, Beijing 100036, China
    Beijing Da Xue Xue Bao 36:620-2. 2004
    ..To investigate the expression of wild type estrogen receptor (wER) and the exon-5 deleted ER (variant ER, vER) in human hepatocellular carcinoma (HCC) samples, and thereafter analyze the possibility of HCC treatment by endocrine therapy...
  45. ncbi request reprint [Expression of angiogenic factors and their clinical significances in acute myeloid leukemia]
    Yi Wang
    State Key Library of Experiment Hematology, Institute of Hematology and Blood Diseases Hospital, CAMS and PUMC, Tianjin, 300020, P R China
    Ai Zheng 23:1423-7. 2004
    ....
  46. ncbi request reprint Reversal of P-glycoprotein-mediated multidrug resistance with small interference RNA (siRNA) in leukemia cells
    Zhi Peng
    The Faculty of Laboratory Medicine, Chongqing Medical University, Chongqing, China
    Cancer Gene Ther 11:707-12. 2004
    ..These findings indicate that siRNA specifically and efficiently interferes with the expression of mdr1 and could be used as a molecularly defined therapeutic approach for MDR in the treatment of leukemia...
  47. ncbi request reprint [Effect of sodium arsenite on the proliferation and cell cycle of keratogenetic cells]
    Xian Ce Sun
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 22:219-20. 2004
  48. ncbi request reprint [Effects of arsenic trioxide, ginseng saponin and beta-elemene on telomere-telomerase system in K562 cell line]
    Yi Wang
    Department of Hematology, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 12:315-20. 2004
    ....
  49. ncbi request reprint [Reversal of multi-drug resistance in K562/A02 cells by small interference RNA of mdr1 gene]
    Zhi Peng
    State Key Laboratory of Experimental Hematology, Institute of Hematology, CAMS and PUMC, Tianjin 300020, China
    Zhonghua Xue Ye Xue Za Zhi 25:5-7. 2004
    ..To investigate the effect of small interference RNA (siRNA) on mdr1 and P-glyco-protein (P-gp) expression of multi-drug resistance (MDR) human leukemia cell line K562/A02...
  50. ncbi request reprint [Effects of fluoride on proliferation and differentiation of rat osteoblasts in vitro and the antagonistic action of vitamin C]
    Ying Zhang
    Department of Occupational and Environmental Health, School of Public Health, China Medical University, Shenyang 110001, China
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 21:250-2. 2003
    ..To study the effects of fluoride on the proliferation and differentiation of osteoblasts in sucking rats and the antagonism of vitamin Cin vitro...
  51. pmc Independent pathways of P-selectin and complement-mediated renal ischemia/reperfusion injury
    Conrad A Farrar
    Department of Nephrology and Transplantation, Guy s Hospital, London, United Kingdom
    Am J Pathol 164:133-41. 2004
    ..We conclude that in vivo interaction between complement and P-selectin is limited because of time and spatial considerations. Consequently, complement and P-selectin pose distinct targets for therapy...
  52. ncbi request reprint Clinical application of radioimmunoguided surgery in colorectal cancer using 125I-labeled carcinoembryonic antigen-specific monoclonal antibody submucosally
    Jin Gu
    Department of Surgery, Beijing Cancer Hospital, Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100036, People s Republic of China
    Dis Colon Rectum 46:1659-66. 2003
    ..The aim of this study was to evaluate the applicability of 125I-labeled carcinoembryonic antigen-specific monoclonal antibody CL58 in clinical radioimmunoguided surgery for colorectal cancer...
  53. ncbi request reprint [Adenoviral vector expressing an antiangiogenic fragment of thrombospondin 1 inhibits the growth of K562 cell xenografts]
    Peng Liu
    State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China
    Zhonghua Yi Xue Za Zhi 83:485-8. 2003
    ..To explore the effect of adenovirus-mediated delivery of an antiangiogenic fragment of human thrombospondin 1 (TSP1(f)) on K562 cell growth in nude mice...
  54. ncbi request reprint [Expression of vascular endothelial growth factor and its receptors KDR and Flt1 in acute myeloid leukemia]
    Yi Wang
    Institute of Hematology, CAMS and PUMC, Tianjin 300020, China
    Zhonghua Xue Ye Xue Za Zhi 24:249-52. 2003
    ..To evaluate the expression of vascular endothelial growth factor (VEGF) and its receptors KDR and Flt1 in patients with acute myeloid leukemia (AML)...
  55. ncbi request reprint Internalization of inactive EGF receptor into endosomes and the subsequent activation of endosome-associated EGF receptors. Epidermal growth factor
    Yi Wang
    Department of Cell Biology and Signal Transduction Research Group, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, T6G 2H7, Canada
    Sci STKE 2002:pl17. 2002
    ..Specific activation of endosome-associated EGFR provides a unique tool to study endosomal signaling of EGFR. This method may also be applied to other receptor tyrosine kinases to study whether they, too, can signal from endosomes...
  56. ncbi request reprint Prognostic significance of c-myc and AIB1 amplification in hepatocellular carcinoma. A broad survey using high-throughput tissue microarray
    Yi Wang
    Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China
    Cancer 95:2346-52. 2002
    ..1, and AIB1 at 20q12 are genetic alterations that are detected frequently in hepatocellular carcinoma (HCC). The authors evaluated the association of these amplifications with the prognosis of patients with HCC...
  57. ncbi request reprint SOX13 is up-regulated in the developing mouse neuroepithelium and identifies a sub-population of differentiating neurons
    Yi Wang
    Human Molecular Genetics Laboratory, Prince Henry s Institute of Medical Research, 246 Clayton Road, Clayton, VIC 3168, Australia
    Brain Res Dev Brain Res 157:201-8. 2005
    ..Our data suggest a role for SOX13 in the specification and/or differentiation of a specific subset of neurons in the developing central nervous system...
  58. ncbi request reprint Fluvastatin prevents renal injury and expression of lactin-like oxidized low-density lipoprotein receptor-1 in rabbits with hypercholesterolemia
    Yong hui Yu
    Department of Pediatrics, Shandong Provincial Hospital, Shandong University, Jinan 250021, China
    Chin Med J (Engl) 118:621-6. 2005
    ....
  59. ncbi request reprint [Effects of high salt diet on blood pressure, renal morphology and osteopontin expression in Sprague-Dawley rat with Ang II-induced renal injury]
    Yong Zheng
    Department of Cardiology, First Hospital of Xi an Jiaotong University, Xi an 710061, China
    Di Yi Jun Yi Da Xue Xue Bao 25:827-32. 2005
    ..To investigate the effect of high-salt diet on blood pressure, renal morphology and osteopontin (OPN) expression in Sprague-Dawley rat with Ang II-induced renal injury...
  60. ncbi request reprint A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints
    Jung Jung Mu
    Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 282:17330-4. 2007
    ....
  61. ncbi request reprint Disruption of palladin leads to defects in definitive erythropoiesis by interfering with erythroblastic island formation in mouse fetal liver
    Xue Song Liu
    Laboratory of Genetic Engineering, Department of Medical Genetics, Institute of Health Sciences, Shanghai Institutes for Biological Sciences Chinese Academy of Sciences, Shanghai, PR China
    Blood 110:870-6. 2007
    ..These data demonstrate that palladin is crucial for definitive erythropoiesis and erythroblastic island formation and, especially, required for normal function of macrophages in fetal liver...
  62. ncbi request reprint [Inducement effect of Meisoindigo on apoptosis of leukemia cell line HL-60 and its mechanism]
    Yi Wang
    State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, P R China
    Ai Zheng 24:1464-8. 2005
    ..This study was to investigate the inducement effect of meisoindigo on apoptosis of myelocytic leukemia cell line HL-60, and explore the possible mechanisms...
  63. ncbi request reprint Anti-tumor effects of Rubratoxin B on cell toxicity, inhibition of cell proliferation, cytotoxic activity and matrix metalloproteinase-2,9
    Tao Wang
    Department of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto 607 8412, Japan
    Toxicol In Vitro 21:646-50. 2007
    ..3 +/- 1.4 microM on human fibrosarcoma cell (HT1080), and Rubratoxin B exhibited inhibitory activities against matrix metalloproteinase (MMP)-2 and 9 on HT 1080 cells with an inhibitory rate of 61.5% and 74.7% at 30 microM, respectively...
  64. ncbi request reprint Effect of ginseng saponin, arsenic trioxide, beta-elemene combined with CTX on telomere-telomerase system in K562 cell line
    Yi Wang
    Department of Hematology, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:1089-95. 2006
    ..When telomerase activity was depressed, the telomere length prolonged a little, indicating K562 cell line may extend telomeres by some alternative way other than telomerase activation...
  65. ncbi request reprint Optical pretargeting of tumor with fluorescent MORF oligomers
    Jiang He
    Department of Radiology, University of California San Francisco, San Francisco, CA 94143, USA
    Mol Imaging Biol 9:17-23. 2007
    ..The use of linear fluorophore-conjugated oligomer duplexes have been little used in animals, and to our knowledge, have not previously been considered for pretargeting applications...
  66. ncbi request reprint Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia
    Ting Lei Gu
    Cell Signaling Technology, Inc, 3 Trask Lane, Danvers, MA 01923, USA
    Blood 108:4202-4. 2006
    ..Thus, the KG-1 cell line provides an in vitro model for the study of FGFR1 fusions associated with leukemia and for the analysis of small molecule inhibitors against FGFR1 fusions...
  67. ncbi request reprint Improved delivery in cell culture of radiolabeled antisense DNAs by duplex formation
    Xinrong Liu
    Department of Radiology, Division of Nuclear Medicine, University of Massachusetts Medical School, Worcester, 01655, USA
    Mol Imaging Biol 8:278-83. 2006
    ..We have investigated the mechanism involved to evaluate whether the approach may be useful for antisense radionuclide imaging...
  68. ncbi request reprint In-situ incorporation of gold nanoparticles of desired sizes into three-dimensional macroporous matrixes
    Shaohua Ding
    State Key Laboratory of Bioelectronics, Department of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, PR China
    Langmuir 22:7105-8. 2006
    ..A highlight of our approach is that it obviates the need for the preformation of various-sized GNPs, which is an indispensable step in many other approaches...
  69. ncbi request reprint Effects of sodium arsenite on catalase activity, gene and protein expression in HaCaT cells
    Xiance Sun
    Department of Occupational and Environmental Health, School of Public Health, China Medical University, Shenyang, Liaoning, PR China
    Toxicol In Vitro 20:1139-44. 2006
    ..CAT activity, mRNA expression and protein levels were decreased by 5-20 micromol/l of sodium arsenite. It is highly suggestive that CAT gene expression and protein levels are affected by arsenic...
  70. ncbi request reprint [Antitumor effect and mechanism of shikonin derivative SYUNZ-7]
    He Huang
    State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, P R China
    Ai Zheng 24:1453-8. 2005
    ..This study was to explore in vitro and in vivo antitumor effects of SYUNZ-7 [2 or 3, 11-bis(phenylsulfanyl)-6-isohexenylnaphthazarin] and the mechanisms...
  71. ncbi request reprint Prostatic acid phosphatase as a target molecule in specific immunotherapy for patients with nonprostate adenocarcinoma
    Yi Wang
    Cancer Vaccine Development Division, Kurume University Research Center for Innovative Cancer Therapy, Kurume, Japan
    J Immunother 28:535-41. 2005
    ..These findings indicate that PAP could be a target molecule in specific immunotherapy for patients with nonprostate adenocarcinomas including colon and gastric cancers...
  72. ncbi request reprint Wnt pathway is involved in pleomorphic adenomas induced by overexpression of PLAG1 in transgenic mice
    Xudong Zhao
    Laboratory of Genetic Engineering, Department of Medical Genetics, Institute of Health Science, Shanghai Institutes for Biologic Sciences of Chinese Academy of Sciences and Shanghai Second Medical University, Shanghai, China
    Int J Cancer 118:643-8. 2006
    ....
  73. ncbi request reprint [Primary clinical study on self-setting calcium phosphate cement in bone defect repair of extremities]
    Wen bo Wang
    Department of Orthopedic Surgery, First Clinical Hospital of Harbin Medical University, Harbin, Heilongjiang, P R China, 150001
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 16:100-2. 2002
    ..To investigate the clinical application of self-setting calcium phosphate cement (CPC) in bone defect repair of extremities...