Xiaofeng Wang

Summary

Publications

  1. doi request reprint Does Low Body Mass Index Matter? Relationship between Body Mass Index and Subjective Well-Being among Long-Lived Women over 95 Years of Age
    Z Liu
    Xiaofeng Wang, School of Life Sciences, Fudan University, 220 Handan Rd, Shanghai 200433, China Tel 86 21 65643714 Fax 86 21 65642426 E mail address
    J Nutr Health Aging 20:99-105. 2016
  2. pmc Several polymorphisms of KCNQ1 gene are associated with plasma lipid levels in general Chinese populations
    Xing Dong Chen
    State Key Laboratory of Genetic Engineering, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    PLoS ONE 7:e34229. 2012
  3. pmc Prevalence and risk factors of gastroesophageal reflux symptoms in a Chinese retiree cohort
    Tiantian Chen
    Clinical Epidemiology Unit, Qilu Hospital of Shandong University, Jinan, 250012, China
    BMC Gastroenterol 12:161. 2012
  4. pmc Rationales, design and recruitment of the Taizhou Longitudinal Study
    Xiaofeng Wang
    State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200433, PR China
    BMC Public Health 9:223. 2009
  5. doi request reprint Common variants of four bilirubin metabolism genes and their association with serum bilirubin and coronary artery disease in Chinese Han population
    Rong Lin
    State Key Laboratory of Genetic Engineering, School of Life Sciences, Institute of Biomedical Sciences, Fudan University, and Ruijin Hospital, Shanghai, China
    Pharmacogenet Genomics 19:310-8. 2009
  6. doi request reprint Association of a BLVRA common polymorphism with essential hypertension and blood pressure in Kazaks
    Rong Lin
    Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China
    Clin Exp Hypertens 33:294-8. 2011
  7. pmc Association between 5p12 genomic markers and breast cancer susceptibility: evidence from 19 case-control studies
    Xiaofeng Wang
    Department of Orthopedics Surgery, Zhongshan Hospital, Fudan University, Shanghai, People s Republic of China
    PLoS ONE 8:e73611. 2013
  8. doi request reprint Association of polymorphisms in the solute carrier organic anion transporter family member 1B1 gene with essential hypertension in the Uyghur population
    Rong Lin
    State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    Ann Hum Genet 75:305-11. 2011
  9. doi request reprint Visual impairment, but not hearing impairment, is independently associated with lower subjective well-being among individuals over 95 years of age: A population-based study
    Zuyun Liu
    Unit of Epidemiology, State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, 200433 Shanghai, China
    Arch Gerontol Geriatr 62:30-5. 2016
  10. doi request reprint Association of heme oxygenase-1 gene polymorphisms with essential hypertension and blood pressure in the Chinese Han population
    Rong Lin
    State Key Laboratory of Genetic Engineering, School of Life Sciences, Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    Genet Test Mol Biomarkers 15:23-8. 2011

Collaborators

Detail Information

Publications32

  1. doi request reprint Does Low Body Mass Index Matter? Relationship between Body Mass Index and Subjective Well-Being among Long-Lived Women over 95 Years of Age
    Z Liu
    Xiaofeng Wang, School of Life Sciences, Fudan University, 220 Handan Rd, Shanghai 200433, China Tel 86 21 65643714 Fax 86 21 65642426 E mail address
    J Nutr Health Aging 20:99-105. 2016
    ..To examine the relationship between body mass index (BMI) and subjective well-being (SWB) among long-lived women over 95 years of age and evaluate whether this relationship is mediated by functional ability...
  2. pmc Several polymorphisms of KCNQ1 gene are associated with plasma lipid levels in general Chinese populations
    Xing Dong Chen
    State Key Laboratory of Genetic Engineering, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    PLoS ONE 7:e34229. 2012
    ..The aim of this study was to investigate whether KCNQ1 polymorphisms influence the levels of the metabolic phenotypes in general Chinese populations...
  3. pmc Prevalence and risk factors of gastroesophageal reflux symptoms in a Chinese retiree cohort
    Tiantian Chen
    Clinical Epidemiology Unit, Qilu Hospital of Shandong University, Jinan, 250012, China
    BMC Gastroenterol 12:161. 2012
    ..To provide additional data on prevalence of GERD and investigate its potential risk factors, we performed this cross-sectional study in the Taizhou Retiree Cohort...
  4. pmc Rationales, design and recruitment of the Taizhou Longitudinal Study
    Xiaofeng Wang
    State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200433, PR China
    BMC Public Health 9:223. 2009
    ..The burdens of non-communicable diseases, such as cardiovascular diseases, diabetes and cancer, have also increased substantially...
  5. doi request reprint Common variants of four bilirubin metabolism genes and their association with serum bilirubin and coronary artery disease in Chinese Han population
    Rong Lin
    State Key Laboratory of Genetic Engineering, School of Life Sciences, Institute of Biomedical Sciences, Fudan University, and Ruijin Hospital, Shanghai, China
    Pharmacogenet Genomics 19:310-8. 2009
    ....
  6. doi request reprint Association of a BLVRA common polymorphism with essential hypertension and blood pressure in Kazaks
    Rong Lin
    Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China
    Clin Exp Hypertens 33:294-8. 2011
    ..3 mmHg, 95.1 mmHg) (p = 0.005 and 0.009, respectively). These findings provide the first genetic evidence for the role of BLVRA on the susceptibility to human essential hypertension and blood pressure...
  7. pmc Association between 5p12 genomic markers and breast cancer susceptibility: evidence from 19 case-control studies
    Xiaofeng Wang
    Department of Orthopedics Surgery, Zhongshan Hospital, Fudan University, Shanghai, People s Republic of China
    PLoS ONE 8:e73611. 2013
    ..We sought to investigate this inconsistency by performing a comprehensive meta-analysis on two wildly studied polymorphisms (rs10941679 and rs4415084) on 5p12...
  8. doi request reprint Association of polymorphisms in the solute carrier organic anion transporter family member 1B1 gene with essential hypertension in the Uyghur population
    Rong Lin
    State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    Ann Hum Genet 75:305-11. 2011
    ..88; 95% CI 1.36-2.60; P= 1.22 × 10(-4)). This study provides preliminary genetic evidence for the role of variant of SLCO1B1 in the susceptibility to human EH in Uyghurs...
  9. doi request reprint Visual impairment, but not hearing impairment, is independently associated with lower subjective well-being among individuals over 95 years of age: A population-based study
    Zuyun Liu
    Unit of Epidemiology, State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, 200433 Shanghai, China
    Arch Gerontol Geriatr 62:30-5. 2016
    ....
  10. doi request reprint Association of heme oxygenase-1 gene polymorphisms with essential hypertension and blood pressure in the Chinese Han population
    Rong Lin
    State Key Laboratory of Genetic Engineering, School of Life Sciences, Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    Genet Test Mol Biomarkers 15:23-8. 2011
    ..7 ± 0.8 vs. 84.5 ± 0.7 mm Hg, adjusted p = 0.009). These findings provide the first genetic evidence for the role of the (GT)n repeat in the HMOX1 promoter in the susceptibility to human EH and the variation of BP...
  11. pmc Common UCP2 variants contribute to serum urate concentrations and the risk of hyperuricemia
    Luyu Yang
    State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China
    Sci Rep 6:27279. 2016
    ..80, P = 0.017). This present study identified a novel gene, UCP2, that influences the serum urate concentration and the risk of hyperuricemia, and the degree of association varies with gender and BMI levels. ..
  12. doi request reprint Prevalence and related factors of chronic kidney disease (CKD) among long-lived individuals (LLI) over 95 years of age
    Zuyun Liu
    Unit of Epidemiology, State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, 200433 Shanghai, China
    Arch Gerontol Geriatr 60:354-8. 2015
    ..e., cardiovascular disease, dementia) and mortality among general populations. However, little is known regarding the prevalence and related factors of CKD among Chinese LLI over 95 years of age...
  13. doi request reprint Prevalence of Age-Related Cataract and Cataract Surgery in a Chinese Adult Population: The Taizhou Eye Study
    Yating Tang
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Xuhui District, Shanghai, China 2Myopia Key Laboratory of the Health Ministry and Visual Impairment and Reconstruction Key Laboratory of Shanghai, Shanghai, China
    Invest Ophthalmol Vis Sci 57:1193-200. 2016
    ..To study the prevalence of age-related cataract (ARC), cataract surgery, and visual outcomes in a Chinese adult population in Taizhou, China...
  14. doi request reprint Blood biomarkers and functional disability among extremely longevous individuals: a population-based study
    Zuyun Liu
    Unit of Epidemiology, State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    J Gerontol A Biol Sci Med Sci 70:623-7. 2015
    ..However, there are limited data for evaluating the potential association of biomarkers with functional disability in an extremely longevous (95+) population...
  15. pmc Mitochondrial genomes and exceptional longevity in a Chinese population: the Rugao longevity study
    Lei Li
    State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Songhu Rd, Shanghai, 200433, China
    Age (Dordr) 37:9750. 2015
    ..Our results provide new clues for genetic mechanisms of longevity and shed light on strategies for evaluating rare mitochondrial variants that underlie complex traits. ..
  16. doi request reprint Common variants in the ATP2B1 gene are associated with hypertension and arterial stiffness in Chinese population
    Yan Wang
    State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    Mol Biol Rep 40:1867-73. 2013
    ..In addition, further genetic and functional research was warranted to elucidate the concrete locus in the ATP2B1 gene that influenced the manifestation of BP and vascular function...
  17. doi request reprint Confirmation of papillary thyroid cancer susceptibility loci identified by genome-wide association studies of chromosomes 14q13, 9q22, 2q35 and 8p12 in a Chinese population
    Yu long Wang
    Department of Head and Neck Surgery, Cancer Hospital, Fudan University, Shanghai, China
    J Med Genet 50:689-95. 2013
    ..33), rs944289 (14q13.3), rs116909374 (14q13.3), rs966423 (2q35) and rs2439302 (8p12). Only the first two SNPs have been validated in independent populations and none were replicated in Chinese populations...
  18. pmc Quantitative assessment of the effect of cytochrome P450 2C9 gene polymorphism and colorectal cancer
    Yuan Zhao
    Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, PR China
    PLoS ONE 8:e60607. 2013
    ..Our result suggest that the *2, *3 polymorphisms of CYP2C9 gene are not associated with CRC susceptibility...
  19. doi request reprint Association of polymorphisms in four bilirubin metabolism genes with serum bilirubin in three Asian populations
    Rong Lin
    Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    Hum Mutat 30:609-15. 2009
    ..Finally, we observed that significant differences of TBIL levels existed among the three populations; however, this could not be completely explained by the differences at the (TA)n repeat polymorphism and SNP rs4148323:G>A...
  20. doi request reprint A meta-analysis of plate fixation versus intramedullary nailing for humeral shaft fractures
    Xiaofeng Wang
    Department of Orthopedics Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, People s Republic of China
    J Orthop Sci 18:388-97. 2013
    ..There is a lack of consensus on whether intramedullary nailing (IMN) or plating is superior for humeral shaft fractures...
  21. pmc Use of serum albumin and activities of daily living to predict mortality in long-lived individuals over 95 years of age: a population-based study
    Zuyun Liu
    Unit of Epidemiology, State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, 220 Handan Rd, Shanghai, 200433, China
    Age (Dordr) 37:9809. 2015
    ..The preliminary findings, if validated and translated, would help clinicians to identify the elderly people at varying mortality risk...
  22. doi request reprint Association between cytotoxic T lymphocyte antigen-4 polymorphism and type 1 diabetes: a meta-analysis
    Zixian Chen
    Department of Orthopaedics Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, PR China
    Gene 516:263-70. 2013
    ..This meta-analysis demonstrated that the G allele of rs231775 of CTLA-4 is a risk factor associated with increased T1D susceptibility...
  23. ncbi request reprint The orientation of the surgical epicondylar axis varies in varus and non-varus knees in the coronal plane
    Yunjie Zhang
    Department of Orthopedic, Zhongshan Hospital, Fudan University, No 180, Rd Fenglin, Shanghai, China
    Knee Surg Sports Traumatol Arthrosc . 2016
    ..To investigate the orientations of the surgical epicondylar axis (SEA) of varus and non-varus knees in the coronal plane...
  24. pmc A genetic variant of the NTCP gene is associated with HBV infection status in a Chinese population
    Jingmin Yang
    Epidemiology unit of MOE Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, 220 Handan Rd, Shanghai, 200433, China
    BMC Cancer 16:211. 2016
    ..To investigate whether genetic variants of the HBV receptor gene NTCP are associated with HBV infection in the Han Chinese population...
  25. pmc The Association of Outdoor Activity and Age-Related Cataract in a Rural Population of Taizhou Eye Study: Phase 1 Report
    Yating Tang
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, 83 Fenyang Road, Xuhui District, Shanghai, China Myopia Key Laboratory of the Health Ministry and Visual Impairment and Reconstruction Key Laboratory of Shanghai, Shanghai, China
    PLoS ONE 10:e0135870. 2015
    ..To study the relationship between outdoor activity and risk of age-related cataract (ARC) in a rural population of Taizhou Eye Study (phrase 1 report)...
  26. pmc Influences of APOA5 variants on plasma triglyceride levels in Uyghur population
    Shuyuan Li
    Ministry of Education Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China Fudan Taizhou Institute of Health Sciences, Taizhou, Jiangsu, China
    PLoS ONE 9:e110258. 2014
    ..Here, we performed a cross-sectional study to address these...
  27. pmc Association between subjective well-being and exceptional longevity in a longevity town in China: a population-based study
    Zuyun Liu
    State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, 200433, Shanghai, China
    Age (Dordr) 36:9632. 2014
    ..The findings imply that interventions that aim to improve elderly individuals' SWB may promote their quality of life and, ultimately, EL...
  28. pmc Common Variants in LRP2 and COMT Genes Affect the Susceptibility of Gout in a Chinese Population
    Zheng Dong
    Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China
    PLoS ONE 10:e0131302. 2015
    ..In addition, we are the first to identify the association between LRP2 and gout in a Chinese population and to confirm this association in Asians. ..
  29. doi request reprint Prevalence and Causes of Visual Impairment in a Chinese Adult Population: The Taizhou Eye Study
    Yating Tang
    Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China Myopia Key Laboratory of the Health Ministry, and Visual Impairment and Reconstruction Key Laboratory of Shanghai, Shanghai, China
    Ophthalmology 122:1480-8. 2015
    ..To study the current prevalence and causes of low vision and blindness in an adult Chinese population...
  30. pmc Potentially functional polymorphisms in the ERCC2 gene and risk of esophageal squamous cell carcinoma in Chinese populations
    Mei ling Zhu
    1 Cancer Institute, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China 2 Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China 3 Department of Oncology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Sci Rep 4:6281. 2014
    ..02-1.33). Interestingly, we consistently found a significant correlation between variant genotypes of these two SNPs and ERCC2 mRNA expression. These findings suggest that potentially functional SNPs in ERCC2 may contribute to ESCC risk. ..
  31. doi request reprint The role of cancer stem cells in cancer metastasis: new perspective and progress
    Xiaofeng Wang
    Department of Orthopaedics, Zhongshan Hospital, Fudan University, Shanghai 200032, China
    Cancer Epidemiol 37:60-3. 2013
    ..In several human cancers, data showed that some phenotypic subsets of CSCs were responsible for cancer metastasis. In this review, we surveyed recent advances in the role and mechanism of metastatic CSCs...
  32. pmc Partial deletions are associated with an increased risk of complete deletion in AZFc: a new insight into the role of partial AZFc deletions in male infertility
    Feng Zhang
    MOE Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    J Med Genet 44:437-44. 2007
    ..Complete AZFc deletion is one of the most frequent causes of male infertility and the roles of partial AZFc deletions (gr/gr and b2/b3 deletions) in spermatogenesis are controversial...