Shui Wang

Summary

Publications

  1. pmc Percutaneous microwave coagulation for eradication of VX2 tumors subcutaneously in rabbits
    Wenbin Zhou
    Department of Breast Surgery, The First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China
    World J Surg Oncol 10:97. 2012
  2. ncbi request reprint [The study on sentinel lymphatic channels by using methylene blue in breast cancer patients]
    Shui Wang
    Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Wai Ke Za Zhi 44:748-50. 2006
  3. pmc A novel finding of sentinel lymphatic channels in early stage breast cancer patients: which may influence detection rate and false-negative rate of sentinel lymph node biopsy
    Minghai Wang
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China
    PLoS ONE 7:e51226. 2012
  4. doi request reprint Genetic variants at chromosome 9p21, 10p15 and 10q22 and breast cancer susceptibility in a Chinese population
    Jiaping Chen
    MOE Key Laboratory of Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing 210029, China
    Breast Cancer Res Treat 132:741-6. 2012
  5. doi request reprint Bone metastasis in a novel breast cancer mouse model containing human breast and human bone
    Tian Song Xia
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China
    Breast Cancer Res Treat 132:471-86. 2012
  6. ncbi request reprint Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility: a case-control analysis
    Xiang Huo
    Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China
    Breast Cancer Res Treat 102:329-37. 2007
  7. ncbi request reprint [Expression of tyrosine kinase Syk in breast cancer and their clinical significance]
    Yong Bin Ding
    Department of General Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Wai Ke Za Zhi 42:137-9. 2004
  8. doi request reprint Genetic variants at 5p12 and risk of breast cancer in Han Chinese
    Xiao an Liu
    Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    J Hum Genet 57:638-41. 2012
  9. doi request reprint Cancer/testis antigen SSX2 enhances invasiveness in MCF-7 cells by repressing ERα signaling
    Ling Chen
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, P R China
    Int J Oncol 40:1986-94. 2012
  10. ncbi request reprint Human tissue-specific microenvironment: an essential requirement for mouse models of breast cancer
    Tian Song Xia
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China
    Oncol Rep 24:203-11. 2010

Collaborators

Detail Information

Publications56

  1. pmc Percutaneous microwave coagulation for eradication of VX2 tumors subcutaneously in rabbits
    Wenbin Zhou
    Department of Breast Surgery, The First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China
    World J Surg Oncol 10:97. 2012
    ..However, PMC for treatment of tumors in low blood-flow tissues has been seldom reported. The aim of this study was to determine the feasibility and safety of PMC for the treatment of tumors in low blood-flow tissues in a rabbit model...
  2. ncbi request reprint [The study on sentinel lymphatic channels by using methylene blue in breast cancer patients]
    Shui Wang
    Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Wai Ke Za Zhi 44:748-50. 2006
    ....
  3. pmc A novel finding of sentinel lymphatic channels in early stage breast cancer patients: which may influence detection rate and false-negative rate of sentinel lymph node biopsy
    Minghai Wang
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China
    PLoS ONE 7:e51226. 2012
    ..The aim of this study was to investigate the sentinel lymphatic channels (SLCs) in the cancerous breast. Whether the type of SLCs influenced the detection rate and false-negative rate of SLNB was also assessed...
  4. doi request reprint Genetic variants at chromosome 9p21, 10p15 and 10q22 and breast cancer susceptibility in a Chinese population
    Jiaping Chen
    MOE Key Laboratory of Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing 210029, China
    Breast Cancer Res Treat 132:741-6. 2012
    ..Our results suggest that the genetic variants at 10q22 may play an important role in breast cancer development in Chinese women, and rs1250009 may be a candidate marker for breast cancer susceptibility...
  5. doi request reprint Bone metastasis in a novel breast cancer mouse model containing human breast and human bone
    Tian Song Xia
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China
    Breast Cancer Res Treat 132:471-86. 2012
    ....
  6. ncbi request reprint Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility: a case-control analysis
    Xiang Huo
    Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China
    Breast Cancer Res Treat 102:329-37. 2007
    ..These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer...
  7. ncbi request reprint [Expression of tyrosine kinase Syk in breast cancer and their clinical significance]
    Yong Bin Ding
    Department of General Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Wai Ke Za Zhi 42:137-9. 2004
    ..To evaluate the effects of the Syk mRNA expression in human breast cancer on tumor growth and metastasis, and to study the correlation of expression of the Syk gene with ER, PR, p53 and HER2/neu...
  8. doi request reprint Genetic variants at 5p12 and risk of breast cancer in Han Chinese
    Xiao an Liu
    Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    J Hum Genet 57:638-41. 2012
    ..We found that the two risk SNPs reported in the European population were neither associated with breast cancer risk in our Chinese population, nor did the fine-mapping SNPs after controlling multiple comparison...
  9. doi request reprint Cancer/testis antigen SSX2 enhances invasiveness in MCF-7 cells by repressing ERα signaling
    Ling Chen
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, P R China
    Int J Oncol 40:1986-94. 2012
    ..The regulation of ERα signaling by target proteins of SSX2 may explain the metastatic potential of breast cancer cells...
  10. ncbi request reprint Human tissue-specific microenvironment: an essential requirement for mouse models of breast cancer
    Tian Song Xia
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China
    Oncol Rep 24:203-11. 2010
    ..The results in this study suggest the human tissue-specific micro-environment is most likely an essential requirement in mouse models of breast cancer...
  11. pmc Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis
    Xiangjun Zhai
    Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China
    BMC Cancer 6:138. 2006
    ....
  12. doi request reprint US-guided percutaneous microwave coagulation of small breast cancers: a clinical study
    Wenbin Zhou
    Department of Breast Surgery and Pathology, Nanjing Medical University, Nanjing, China
    Radiology 263:364-73. 2012
    ..To determine the feasibility of percutaneous microwave coagulation (PMC) for the treatment of small solitary breast cancers...
  13. doi request reprint A novel mouse model of gastric cancer with human gastric microenvironment
    Ming Jie Zheng
    Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu Province, China
    Cancer Lett 325:108-15. 2012
    ....
  14. doi request reprint A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women
    Yan Wang
    Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China
    Carcinogenesis 29:1197-201. 2008
    ..13, 95% CI = 1.05-4.33) compared with wild-type 302/302 genotype. These findings indicate that the MNS16A variant in the hTERT gene may contribute to the risk of breast cancer development and metastasis in Chinese women...
  15. ncbi request reprint Functional variants in the promoter of interleukin-1beta are associated with an increased risk of breast cancer: a case-control analysis in a Chinese population
    Jiyong Liu
    Laboratory of Reproductive Medicine and Applied Toxicology, Nanjing Medical University, and Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, 210029, People s Republic of China
    Int J Cancer 118:2554-8. 2006
    ..27-fold (95% CI=1.01-1.60) increased risk was observed with the -31C-511T common haplotype. These findings indicate that these 2 IL-1beta promoter variants may contribute to risk of developing breast cancer in the Chinese population...
  16. ncbi request reprint Variant genotypes of CDKN1A and CDKN1B are associated with an increased risk of breast cancer in Chinese women
    Hongxia Ma
    Laboratory of Reproductive Medicine and Applied Toxicology, Nanjing Medical University, Nanjing, China
    Int J Cancer 119:2173-8. 2006
    ..Further large and functional studies are needed to confirm our findings...
  17. doi request reprint Genetic variation in a hsa-let-7 binding site in RAD52 is associated with breast cancer susceptibility
    Yue Jiang
    State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing 210029, China
    Carcinogenesis 34:689-93. 2013
    ..These findings indicate that rs7963551 located at hsa-let-7 binding site may alter expression of RAD52 through modulating miRNA-mRNA interaction and contribute to the development of breast cancer in Chinese women...
  18. pmc The risk of amenorrhea is related to chemotherapy-induced leucopenia in breast cancer patients receiving epirubicin and taxane based chemotherapy
    Wenbin Zhou
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China
    PLoS ONE 7:e37249. 2012
    ..Furthermore, the incidence of CIA was also assessed...
  19. doi request reprint Reactivation of Syk gene by AZA suppresses metastasis but not proliferation of breast cancer cells
    Tian Song Xia
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, 210029 Nanjing, People s Republic of China
    Med Oncol 29:448-53. 2012
    ....
  20. ncbi request reprint EGF promoter SNPs, plasma EGF levels and risk of breast cancer in Chinese women
    Yan Wang
    Laboratory of Reproductive Medicine, Cancer Research Center of Nanjing Medical University, Nanjing, China
    Breast Cancer Res Treat 111:321-7. 2008
    ..These findings indicated that plasma EGF levels served as a protective marker against breast cancer in our study and EGF G-1380A variant might be a modifier on it. Further studies are warranted to verify these findings...
  21. pmc Genetic variants at 14q24.1 and breast cancer susceptibility: a fine-mapping study in Chinese women
    Hongxia Ma
    MOE Key Laboratory of Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China
    DNA Cell Biol 31:1114-20. 2012
    ..These findings suggest that common variants at 14q24.1 might not be associated with the risk of breast cancer in the Chinese population, which will need the replication in additional larger studies...
  22. pmc Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts
    Junjie Zou
    Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjng, Jiangsu Province, China
    J Cardiothorac Surg 6:69. 2011
    ..Rapamycin is an immunosuppressive agent which also exhibits marked antiproliferative properties. We investigated whether rapamycin-loaded nanoparticles(NPs) can reduce neointima formation in a rat model of vein graft disease...
  23. ncbi request reprint Hypermethylation of Syk gene in promoter region associated with oncogenesis and metastasis of gastric carcinoma
    Shui Wang
    Department of General Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
    World J Gastroenterol 10:1815-8. 2004
    ..The relation between silencing of the Syk gene and methylation of Syk promoter region was also studied...
  24. ncbi request reprint Postmenopausal hormone therapy is associated with in situ breast cancer risk
    Xiao Jian Ni
    Department of Breast Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    Asian Pac J Cancer Prev 13:3917-25. 2012
    ..The aim of our present study was to review and summarize the evidence provided by longitudinal studies on the association between postmenopausal HT use and BCIS risk...
  25. pmc Molecular subtype classification is a determinant of non-sentinel lymph node metastasis in breast cancer patients with positive sentinel lymph nodes
    Wenbin Zhou
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China
    PLoS ONE 7:e35881. 2012
    ..The purpose of this study was to determine whether molecular subtype classification was associated with non-sentinel lymph nodes (NSLN) metastasis in patients with a positive SLN...
  26. doi request reprint Three polymorphisms in interleukin-1β gene and risk for breast cancer: a meta-analysis
    Xiaoan Liu
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China
    Breast Cancer Res Treat 124:821-5. 2010
    ..49 for heterogeneity). For rs16944 (C > T) and rs1143634 (C > T), no significant associations were found in all genetic models. In conclusion, the present meta-analysis suggests that rs1143627 is associated with breast cancer risk...
  27. pmc Incidence of chemotherapy-induced amenorrhea associated with epirubicin, docetaxel and navelbine in younger breast cancer patients
    Wen Bin Zhou
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, 210029 Nanjing, PR China
    BMC Cancer 10:281. 2010
    ..The rates of chemotherapy-induced amenorrhea (CIA) associated with docetaxel-based regimens reported by previous studies are discordant. For navelbine-based chemotherapies, rates of CIA have seldom been reported...
  28. doi request reprint Bloody nipple discharge is a predictor of breast cancer risk: a meta-analysis
    Ling Chen
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China
    Breast Cancer Res Treat 132:9-14. 2012
    ..707 for heterogeneity). Therefore, bloody nipple discharge could be a predictor of breast cancer risk among different colors of discharges. The symptom of bloody nipple discharge is helpful to the stratification of preoperative patients...
  29. doi request reprint Surgical outcomes for gastric cancer of a single institute in southeast China
    Yong Bin Ding
    Department of General Surgery, First Affiliated Hospital of Nanjing Medical University, China
    Am J Surg 203:217-21. 2012
    ..In recent years, with social and economic development and lifestyle changes, the incidence of gastric cancer as well as the surgical results and prognoses of patients with gastric cancer have changed significantly in southeast China...
  30. pmc Genetic variants at 1p11.2 and breast cancer risk: a two-stage study in Chinese women
    Yue Jiang
    State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China
    PLoS ONE 6:e21563. 2011
    ..To explore the genetic variants in this region associated with breast cancer in Chinese women, we conducted a two-stage fine-mapping study with a total of 1792 breast cancer cases and 1867 controls...
  31. doi request reprint Tumor-derived VEGF-C, but not VEGF-D, promotes sentinel lymph node lymphangiogenesis prior to metastasis in breast cancer patients
    Ying Chun Zhao
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China
    Med Oncol 29:2594-600. 2012
    ..05). This study demonstrates that primary breast tumors induce SLN lymphangiogenesis before metastasis occurs and that tumor-derived VEGF-C, but not VEGF-D, plays an important role in SLN lymphangiogenesis in breast cancer...
  32. pmc Comparison of Ablation Zones among Different Tissues Using 2450-MHz Cooled-Shaft Microwave Antenna: Results in Ex Vivo Porcine Models
    Wenbin Zhou
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China
    PLoS ONE 8:e71873. 2013
    ..The aim of this study was to compare the extent of microwave ablation zone in muscle, liver and adipose tissue in ex vivo porcine models and assess the shape of microwave coagulation zone among these tissues...
  33. doi request reprint Genistein inhibits MDA-MB-231 triple-negative breast cancer cell growth by inhibiting NF-κB activity via the Notch-1 pathway
    Hong Pan
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, P R China
    Int J Mol Med 30:337-43. 2012
    ..Further preclinical and clinical studies are warranted to further investigate the application of Gen for the treatment of triple-negative breast cancer...
  34. doi request reprint A functional epidermal growth factor (EGF) polymorphism, EGF serum levels and renal cell carcinoma risk in a Chinese population
    Jian Zhu
    Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China
    J Hum Genet 55:236-40. 2010
    ..These results suggested that the EGF G61A polymorphism is involved in the etiology of RCC and thus may be a marker for genetic susceptibility to RCC in Chinese populations. Larger studies are warranted to validate our findings...
  35. pmc Meta-analysis of sentinel lymph node biopsy at the time of prophylactic mastectomy of the breast
    Wen Bin Zhou
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    Can J Surg 54:300-6. 2011
    ..The benefit of sentinel lymph node biopsy (SLNB) at the time of prophylactic mastectomy is controversial, and we performed a meta-analysis of the reported data to assess that benefit...
  36. doi request reprint Management of chylous leakage after breast surgery: report of four cases
    Wenbin Zhou
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, 210029, Nanjing, PR China
    Surg Today 41:1639-43. 2011
    ..Of the 20 pooled cases, most were cured with conservative treatment and only three cases were cured with surgical treatment...
  37. doi request reprint Evaluation of genetic variants in microRNA biosynthesis genes and risk of breast cancer in Chinese women
    Yue Jiang
    State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China MOE Key Laboratory of Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China Section of Clinical Epidemiology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Cancer Center, Nanjing Medical University, Nanjing, China
    Int J Cancer 133:2216-24. 2013
    ..31 × 10(-7) , 9.29 × 10(-7) for miR-106b and miR-579, respectively). Our findings suggested that DGCR8 rs417309 G > A might affect breast cancer risk through the interruption of miRNA binding. ..
  38. pmc SOD mimetic improves the function, growth, and survival of small-size liver grafts after transplantation in rats
    Yi Yao Cui
    Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    Transplantation 94:687-94. 2012
    ..However, its pathogenesis is poorly understood, and few effective interventions have been attempted...
  39. doi request reprint Toremifene is an effective and safe alternative to tamoxifen in adjuvant endocrine therapy for breast cancer: results of four randomized trials
    Wen Bin Zhou
    Department of Breast Surgery, Nanjing Medical University, Nanjing, 210029, China
    Breast Cancer Res Treat 128:625-31. 2011
    ..Toremifene was a convincing and safe change for tamoxifen in adjuvant endocrine therapy...
  40. ncbi request reprint Ectopic expression of RhoBTB2 inhibits migration and invasion of human breast cancer cells
    Li jun Ling
    Department of Breast Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    Cancer Biol Ther 10:1115-22. 2010
    ..Our findings suggest that understanding RhoBTB2-mediated migration and suppression of invasion is critical to the development of new therapies designed to prevent and treat patients with breast cancer metastasis...
  41. pmc The influence of family history and histological stratification on breast cancer risk in women with benign breast disease: a meta-analysis
    Wen Bin Zhou
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China
    J Cancer Res Clin Oncol 137:1053-60. 2011
    ..Furthermore, it is unclear whether family history increases risk in women with various subtypes of BBD...
  42. ncbi request reprint [Preliminary study on lymphocyte subsets of sentinel lymph nodes in breast cancer patients]
    Shui Wang
    Department of General Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Zhong Liu Za Zhi 26:220-2. 2004
    ..To study the lymphocyte subsets of sentinel lymph nodes (SLN) in breast cancer patients...
  43. doi request reprint A novel orthotopic and metastatic mouse model of breast cancer in human mammary microenvironment
    Jue Wang
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, 210029, Nanjing, China
    Breast Cancer Res Treat 120:337-44. 2010
    ..Consequently, the BOM model contributed to the orthotopic tumor formation of 100% (11/11) and the metastatic tumor formation of 72.7% (8/11)...
  44. doi request reprint Pulmonary embolism caused by a thrombosed external iliac venous aneurysm
    Junjie Zou
    Division of Vascular Surgery, Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, People s Republic of China
    Ann Vasc Surg 25:982.e15-8. 2011
    ..The patient was diagnosed using computer tomography pulmonary angiography and computer tomography iliac venography. This case represents the first patient known to have an external iliac VA that progressed to pulmonary embolism...
  45. ncbi request reprint A novel mouse model of human breast cancer stem-like cells with high CD44+CD24-/lower phenotype metastasis to human bone
    Li jun Ling
    Department of General Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China
    Chin Med J (Engl) 121:1980-6. 2008
    ..In this study, we used human breast cancer stem-like cells and human bone to build a novel "human-source" model of human breast cancer skeletal metastasis...
  46. pmc Low serum creatine kinase levels in breast cancer patients: a case-control study
    Hong Pan
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China
    PLoS ONE 8:e62112. 2013
    ..Previous studies provide an ambiguous picture of creatine kinase (CK) expression and activities in malignancy. The aim of this study was to investigate the role of serum CK level in breast cancer patients...
  47. pmc STAT3 mediates resistance of CD44(+)CD24(-/low) breast cancer stem cells to tamoxifen in vitro
    Xiaoyan Wang
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China
    J Biomed Res 26:325-35. 2012
    ..Meanwhile, the knock-down of STAT3 in TAM-R resulted in an increase in sensitivity to tamoxifen. It is concluded that STAT3 plays an essential role in breast cancer stem cells, which correlated with tamoxifen resistance...
  48. doi request reprint Celecoxib enhanced the sensitivity of cancer cells to anticancer drugs by inhibition of the expression of P-glycoprotein through a COX-2-independent manner
    Wenhong Xia
    Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 210029, P R China
    J Cell Biochem 108:181-94. 2009
    ..Our study suggested that celecoxib was a potential agent for enhancement of the sensitivity of cancer cells to anticancer drugs. It also provided a links between epigenetic change of MDR1 and drug response of cancer cells...
  49. ncbi request reprint Joint effects of single nucleotide polymorphisms in P53BP1 and p53 on breast cancer risk in a Chinese population
    Hongxia Ma
    Laboratory of Reproductive Medicine, Department of Epidemiology and Biostatistics, Nanjing Medical University, and Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, China
    Carcinogenesis 27:766-71. 2006
    ..Further functional studies are needed to confirm our findings...
  50. doi request reprint Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts
    Junjie Zou
    Division of Vascular Surgery, Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjng, Jiangsu Province, China
    Ann Vasc Surg 25:538-46. 2011
    ..Rapamycin is an immunosuppressive agent which also exhibits marked antiproliferative properties. We investigated whether rapamycin-loaded NPs can reduce neointima formation of vein graft disease in a rat model...
  51. ncbi request reprint Association between the Ku70-1310C/G promoter polymorphism and cancer risk: a meta-analysis
    Lu Xu
    Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China
    Asian Pac J Cancer Prev 13:683-7. 2012
    ..35, 95%CI=1.11-1.64; CG/GG vs. CC: OR=1.37, 95%CI=1.14-1.65). Additionally, variant genotypes were associated with a significantly increased breast cancer risk (GG vs. CC: OR=1.80, 95%CI=1.26-2.56; GG vs. CC/CG: OR=1.40, 95%CI=1.01-1.95)...
  52. doi request reprint Cytotoxic and antibacterial triterpenoids derivatives from Clematis ganpiniana
    Qiang Ding
    Department of Breast Surgery, First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China
    J Ethnopharmacol 126:382-5. 2009
    ..The Naxi people traditionally used Clematis ganpiniana's (Lévl. Et Vant.) as a diuretic agent, an anti-inflammatory and anticancer remedy...
  53. pmc JNK/AP-1 pathway is involved in tumor necrosis factor-alpha induced expression of vascular endothelial growth factor in MCF7 cells
    Yongmei Yin
    Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People s Republic of China
    Biomed Pharmacother 63:429-35. 2009
    ..These data suggest that the pro-inflammatory cytokine TNF-alpha is a critical regulator of VEGF expression in breast cancer cells, at least partially via a JNK and AP-1 dependent pathway...
  54. ncbi request reprint [Hypermethylation of syk gene in promoter region is associated with oncogenesis, metastasis of breast carcinoma]
    Yong Bin Ding
    Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
    Zhonghua Yi Xue Za Zhi 84:290-3. 2004
    ..To investigate the relationship between methylation of syk (spleen tyrosine kinase) gene in promoter region and oncogenesis, metastasis in breast carcinoma...
  55. pmc Meta-analysis on the association between non-steroidal anti-inflammatory drug use and ovarian cancer
    Xiaojian Ni
    Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, China
    Br J Clin Pharmacol 75:26-35. 2013
    ..However, results from these studies have been inconsistent. The aim of our study was to review and summarize the evidence provided by longitudinal studies on the association between NSAID use and ovarian cancer risk...
  56. ncbi request reprint Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population
    Hongxia Ma
    Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China
    Cancer Lett 240:261-7. 2006
    ..03; 95% CI, 0.74-1.42 for SNP309 TG and GG; and adjusted OR, 1.09; 95% CI, 0.83-1.43 for Del1518 +/- and -/-). These findings suggest that these two MDM2 promoter variants may not play a major role in the etiology of breast cancer...