Jia He Wang

Summary

Publications

  1. ncbi request reprint Jolkinolide B from Euphorbia fischeriana Steud induces in human leukemic cells apoptosis via JAK2/STAT3 pathways
    Jia He Wang
    Department of Geriatrics, China Medical University, Shenyang, China
    Int J Clin Pharmacol Ther 51:170-8. 2013
  2. doi request reprint 2-Hydroxy-3-methylanthraquinone from Hedyotis diffusa WILLD induces apoptosis via alteration of Fas/FasL and activation of caspase-8 in human leukemic THP-1 cells
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University Shenyang, PR China
    Arch Med Res 42:577-83. 2011
  3. doi request reprint Active lipids of Ganoderma lucidum spores-induced apoptosis in human leukemia THP-1 cells via MAPK and PI3K pathways
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang, China
    J Ethnopharmacol 139:582-9. 2012
  4. pmc Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells
    Huiyan Niu
    Department of Geriatrics, Shengjing Hospital, China Medical University, Shenyang 110004, China
    J Exp Clin Cancer Res 30:28. 2011
  5. doi request reprint Jolkinolide B from Euphorbia fischeriana Steud induces apoptosis in human leukemic U937 cells through PI3K/Akt and XIAP pathways
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang 110004, PR China
    Mol Cells 32:451-7. 2011
  6. doi request reprint Escherichia coli induces apoptosis in human monocytic U937 cells through the Fas/FasL signaling pathway
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang 110004, People s Republic of China
    Mol Cell Biochem 358:95-104. 2011
  7. doi request reprint Staphylococcus aureus induces apoptosis of human monocytic U937 cells via NF-kappaB signaling pathways
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang, PR China
    Microb Pathog 49:252-9. 2010
  8. doi request reprint 2-hydroxy-3-methylanthraquinone from Hedyotis diffusa Willd induces apoptosis in human leukemic U937 cells through modulation of MAPK pathways
    Nan Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang 110004, China
    Arch Pharm Res 36:752-8. 2013
  9. doi request reprint Pseudolaric acid B induces apoptosis in U937 human leukemia cells via caspase-9‑mediated activation of the mitochondrial death pathway
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P R China
    Mol Med Rep 8:787-93. 2013
  10. ncbi request reprint C-jun N-terminal kinase-mediated signaling is essential for Staphylococcus aureus-induced U937 apoptosis
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital, China Medical University, Shenyang 110004, China
    Chin Med Sci J 24:26-9. 2009

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Jolkinolide B from Euphorbia fischeriana Steud induces in human leukemic cells apoptosis via JAK2/STAT3 pathways
    Jia He Wang
    Department of Geriatrics, China Medical University, Shenyang, China
    Int J Clin Pharmacol Ther 51:170-8. 2013
    ..Moreover, the triggering of caspase-3, -8, and -9 activation mediated apoptotic induction...
  2. doi request reprint 2-Hydroxy-3-methylanthraquinone from Hedyotis diffusa WILLD induces apoptosis via alteration of Fas/FasL and activation of caspase-8 in human leukemic THP-1 cells
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University Shenyang, PR China
    Arch Med Res 42:577-83. 2011
    ..The current study determines the role of Fas/FasL in THP-1 cell apoptosis induced by 2-hydroxy-3-methylanthraquinone from H. diffusa...
  3. doi request reprint Active lipids of Ganoderma lucidum spores-induced apoptosis in human leukemia THP-1 cells via MAPK and PI3K pathways
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang, China
    J Ethnopharmacol 139:582-9. 2012
    ..Ganoderma lucidum (Lingzhi) is traditionally drug, which has been traditionally effective used in the treatment of chronic hepatopathy, hypertension, hyperglycemia and cancer...
  4. pmc Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells
    Huiyan Niu
    Department of Geriatrics, Shengjing Hospital, China Medical University, Shenyang 110004, China
    J Exp Clin Cancer Res 30:28. 2011
    ..To elucidate whether rapamycin, the inhibitor of mTOR (mammalian target of rapamycin), can potentiate the cytotoxic effect of docetaxel in lung cancer cells and to probe the mechanism underlying such enhancement...
  5. doi request reprint Jolkinolide B from Euphorbia fischeriana Steud induces apoptosis in human leukemic U937 cells through PI3K/Akt and XIAP pathways
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang 110004, PR China
    Mol Cells 32:451-7. 2011
    ..Moreover, triggering of caspase-3 and -9 activation mediated apoptotic induction...
  6. doi request reprint Escherichia coli induces apoptosis in human monocytic U937 cells through the Fas/FasL signaling pathway
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang 110004, People s Republic of China
    Mol Cell Biochem 358:95-104. 2011
    ..Taken together, these results clearly indicate that receptor-mediated phagocytosis of E. coli induces apoptosis. Moreover, our findings suggest a possible regulatory role of Fas/FasL in the pathway of E. coli infection...
  7. doi request reprint Staphylococcus aureus induces apoptosis of human monocytic U937 cells via NF-kappaB signaling pathways
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang, PR China
    Microb Pathog 49:252-9. 2010
    ..aureus led to caspase-3 activity. Collectively, these data define a pathway that infection of primary monocytes and U937 cells with S. aureus induces a caspase-dependent inhibition of NF-kappaB...
  8. doi request reprint 2-hydroxy-3-methylanthraquinone from Hedyotis diffusa Willd induces apoptosis in human leukemic U937 cells through modulation of MAPK pathways
    Nan Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang 110004, China
    Arch Pharm Res 36:752-8. 2013
    ..Moreover, the triggering of caspase-3 activation mediated apoptotic induction...
  9. doi request reprint Pseudolaric acid B induces apoptosis in U937 human leukemia cells via caspase-9‑mediated activation of the mitochondrial death pathway
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P R China
    Mol Med Rep 8:787-93. 2013
    ..Moreover, the activation of caspase‑3 and -9 mediated the apoptotic induction...
  10. ncbi request reprint C-jun N-terminal kinase-mediated signaling is essential for Staphylococcus aureus-induced U937 apoptosis
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital, China Medical University, Shenyang 110004, China
    Chin Med Sci J 24:26-9. 2009
    ..To investigate the effect of SP600125, a specific c-jun N-terminal protein kinase (JNK) inhibitor, on Staphylococcus aureus (S. aureus)-induced U937 cell death and the underlying mechanism...
  11. ncbi request reprint Phosphoinositide 3-kinase/Akt and nuclear factor-kappaB are involved in Staphylococcus aureus-induced apoptosis in U937 cells
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital, China Medical University, Shenyang 110004, China
    Chin Med Sci J 24:231-5. 2009
    ..To explore the mechanisms involved in Staphylococcus aureus (S. aureus) invading human monocytic U937 cells...
  12. ncbi request reprint Involvement of phosphatidylinositol 3-Kinase/Akt signaling pathway in β1 integrin-mediated internalization of Staphylococcus aureus by alveolar epithelial cells
    Jia He Wang
    Department of Geriatrics, Shengjing Hospital of China Medical University, Shenyang, 110004, P R China
    J Microbiol 51:644-50. 2013
    ..aureus. Our results suggest that the phosphatidylinositol 3-kinase/Akt signaling pathway plays an important role in β1 integrin-mediated internalization of S. aureus by alveolar epithelial cells. ..
  13. ncbi request reprint Involvement of p38 mitogen-activated protein kinase in E. coli-induced U937 apoptosis
    Jia He Wang
    Department of Geriatrics, Second Affiliated Hospital, China Medical University, Shenyang 110004
    Chin Med Sci J 22:49-53. 2007
    ..To investigate whether the effect of E. coli on U937 cell lines apoptosis is mediated via p38 mitogen-activated protein kinase (MAPK) activation...
  14. doi request reprint Pseudolaric acid B induces caspase-dependent cell death in human ovarian cancer cells
    Bo Yu
    Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P R China
    Oncol Rep 31:849-57. 2014
    ..Moreover, the triggering of caspase-3 and -9 activation mediated apoptotic induction. Our results suggest that PAB may be a new therapeutic option for the treatment of ovarian cancers...
  15. ncbi request reprint Health-related quality of life in women with breast cancer: a literature-based review of psychometric properties of breast cancer-specific measures
    Hui yan Niu
    Department of Geriatrics, Shengjing Hospital, China Medical University, Shenyang, China E mail
    Asian Pac J Cancer Prev 15:3533-6. 2014
    ..The aim of this review was to provide a literature-based assessment of the validity, reliability and responsiveness of breast cancer-specific HRQL instruments in women breast cancer patients...
  16. ncbi request reprint Expanding expression of the 5-lipoxygenase/leukotriene B4 pathway in atherosclerotic lesions of diabetic patients promotes plaque instability
    Yi Jun Zhou
    Department of Endocrinology and Metabolism, Fourth Affiliated Hospital, China Medical University, Shenyang 110032, PR China
    Biochem Biophys Res Commun 363:30-6. 2007
    ..Hence, anti-LTs may be useful, not only in reducing atherogenesis, but also in the prevention and treatment of acute atherothrombotic events in diabetic patients...