Yue Peng Wang
Zhou Q, Wei S, Wang H, Wang Q, Li W, Li G, et al
. Crucial Role of ROCK2-Mediated Phosphorylation and Upregulation of FHOD3 in the Pathogenesis of Angiotensin II-Induced Cardiac Hypertrophy. Hypertension. 2017;69:1070-1083 pubmed publisher
..Collectively, our results demonstrated the importance of ROCK2 regulated FHOD3 expression and activation in Ang-II-induced myofibrillogenesis, thus provided a novel mechanism for the pathogenesis of Ang-II-induced cardiac hypertrophy. ..
Chen Y, Wang Q, Li C, Hou J, Chen X, Zhou Q, et al
. Haplodeficiency of activin receptor-like kinase 4 alleviates myocardial infarction-induced cardiac fibrosis and preserves cardiac function. J Mol Cell Cardiol. 2017;105:1-11 pubmed publisher
Fei Y, Li W, Hou J, Guo K, Chen X, Chen Y, et al
. Oxidative Stress-Induced Afterdepolarizations and Protein Kinase C Signaling. Int J Mol Sci. 2017;18: pubmed publisher
..H?O? induced afterdepolarizations via the activation of PKC and the enhancement of ICa,L and INa,L. These results provide evidence of a link between oxidative stress, PKC activation and afterdepolarizations. ..
Wang Q, Yu Y, Zhang P, Chen Y, Li C, Chen J, et al
. The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation. Basic Res Cardiol. 2017;112:47 pubmed publisher
Hou J, Li W, Fei Y, Chen Y, Wang Q, Wang Y, et al
. ICaL and Ito mediate rate-dependent repolarization in rabbit atrial myocytes. J Physiol Biochem. 2018;74:57-67 pubmed publisher
..In conclusion, our study demonstrated that Ito and ICaL mediate RDR of AP in rabbit atrium, while minimal effect of INaL was seen. ..