Arthur S Walters

Summary

Publications

  1. pmc Prevalence of stroke in Restless Legs Syndrome: Initial Results Point to the Need for More Sophisticated Studies
    Arthur S Walters
    Dept of Neurology Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Open Neurol J 4:73-7. 2010
  2. ncbi request reprint Long-term follow-up on restless legs syndrome patients treated with opioids
    A S Walters
    New Jersey Neuroscience Institute at JFK Medical Center Edison, New Jersey 08818, USA
    Mov Disord 16:1105-9. 2001
  3. ncbi request reprint Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome
    Arthur S Walters
    New Jersey Neuroscience Institute, JFK Medical Center, Edison, NJ 08818, USA
    Sleep Med 4:121-32. 2003
  4. ncbi request reprint The scoring of movements in sleep
    Arthur S Walters
    Seton Hall University School of Graduate Medical Education, New Jersey Neuroscience Institute at JFK Medical Center, Edison, NJ 08818, USA
    J Clin Sleep Med 3:155-67. 2007
  5. ncbi request reprint Clinical identification of the simple sleep-related movement disorders
    Arthur S Walters
    JFK Medical Center, New Jersey Neuroscience Institute, 65 James St, Edison, NJ 08818, USA
    Chest 131:1260-6. 2007
  6. ncbi request reprint Ropinirole is effective in the treatment of restless legs syndrome. TREAT RLS 2: a 12-week, double-blind, randomized, parallel-group, placebo-controlled study
    Arthur S Walters
    New Jersey Neuroscience Institute at JFK Medical Center, Edison, New Jersey 08818, USA
    Mov Disord 19:1414-23. 2004
  7. doi request reprint Gabapentin enacarbil in restless legs syndrome: a phase 2b, 2-week, randomized, double-blind, placebo-controlled trial
    Arthur S Walters
    Department of Neurology, Vanderbilt University Medical Center, 1161 21st Ave, Nashville, TN 37232 2551, USA
    Clin Neuropharmacol 32:311-20. 2009
  8. pmc Comparative effectiveness of maxillomandibular advancement and uvulopalatopharyngoplasty for the treatment of moderate to severe obstructive sleep apnea
    Scott B Boyd
    Department of Oral and Maxillofacial Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232 2103, USA
    J Oral Maxillofac Surg 71:743-51. 2013
  9. ncbi request reprint Half of patients with obstructive sleep apnea have a higher NREM AHI than REM AHI
    Fouzia Siddiqui
    NJ Neuroscience Institute at JFK Medical Center, Seton Hall University School of Graduate Medical Education, Edison, NJ 08818 USA
    Sleep Med 7:281-5. 2006
  10. ncbi request reprint Clinically significant but unsuspected restless legs syndrome in patients with sleep apnea
    Sowmya Lakshminarayanan
    Center for Sleep Disorders, Treatment, Research and Education, New Jersey Neuroscience Institute at John F Kennedy Medical Center, Edison, New Jersey 08818, USA
    Mov Disord 20:501-3. 2005

Detail Information

Publications37

  1. pmc Prevalence of stroke in Restless Legs Syndrome: Initial Results Point to the Need for More Sophisticated Studies
    Arthur S Walters
    Dept of Neurology Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Open Neurol J 4:73-7. 2010
    ..Acute clinical stroke has been linked to the immediate onset of RLS, and epidemiological studies suggest the possibility that RLS may also lead to stroke...
  2. ncbi request reprint Long-term follow-up on restless legs syndrome patients treated with opioids
    A S Walters
    New Jersey Neuroscience Institute at JFK Medical Center Edison, New Jersey 08818, USA
    Mov Disord 16:1105-9. 2001
    ..Opioids seem to have long-term effectiveness in the treatment of RLS and PLMS, but patients on long-term opioid therapy should be clinically or polysomnographically monitored periodically for the development of sleep apnea...
  3. ncbi request reprint Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome
    Arthur S Walters
    New Jersey Neuroscience Institute, JFK Medical Center, Edison, NJ 08818, USA
    Sleep Med 4:121-32. 2003
    ..Moreover, RLS is primarily a subjective disorder. Therefore, a subjective scale is at present the optimal instrument to meet this need...
  4. ncbi request reprint The scoring of movements in sleep
    Arthur S Walters
    Seton Hall University School of Graduate Medical Education, New Jersey Neuroscience Institute at JFK Medical Center, Edison, NJ 08818, USA
    J Clin Sleep Med 3:155-67. 2007
    ..Because of limited or absent evidence for reliability and/or validity, a standardized RAND/UCLA consensus process was employed for recommendation of specific rules for the scoring of sleep-associated movements...
  5. ncbi request reprint Clinical identification of the simple sleep-related movement disorders
    Arthur S Walters
    JFK Medical Center, New Jersey Neuroscience Institute, 65 James St, Edison, NJ 08818, USA
    Chest 131:1260-6. 2007
    ....
  6. ncbi request reprint Ropinirole is effective in the treatment of restless legs syndrome. TREAT RLS 2: a 12-week, double-blind, randomized, parallel-group, placebo-controlled study
    Arthur S Walters
    New Jersey Neuroscience Institute at JFK Medical Center, Edison, New Jersey 08818, USA
    Mov Disord 19:1414-23. 2004
    ..Ropinirole improves symptoms, associated sleep disturbance, and QoL of RLS patients and is generally well tolerated...
  7. doi request reprint Gabapentin enacarbil in restless legs syndrome: a phase 2b, 2-week, randomized, double-blind, placebo-controlled trial
    Arthur S Walters
    Department of Neurology, Vanderbilt University Medical Center, 1161 21st Ave, Nashville, TN 37232 2551, USA
    Clin Neuropharmacol 32:311-20. 2009
    ..Assess the efficacy and tolerability of gabapentin enacarbil (GEn), a transported prodrug of gabapentin with improved gabapentin exposure, in adults with moderate-to-severe primary restless legs syndrome...
  8. pmc Comparative effectiveness of maxillomandibular advancement and uvulopalatopharyngoplasty for the treatment of moderate to severe obstructive sleep apnea
    Scott B Boyd
    Department of Oral and Maxillofacial Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232 2103, USA
    J Oral Maxillofac Surg 71:743-51. 2013
    ..To directly compare the clinical effectiveness of maxillomandibular advancement (MMA) and uvulopalatopharyngoplasty (UPPP)--performed alone and in combination--for the treatment of moderate to severe obstructive sleep apnea (OSA)...
  9. ncbi request reprint Half of patients with obstructive sleep apnea have a higher NREM AHI than REM AHI
    Fouzia Siddiqui
    NJ Neuroscience Institute at JFK Medical Center, Seton Hall University School of Graduate Medical Education, Edison, NJ 08818 USA
    Sleep Med 7:281-5. 2006
    ..Males, as well as older individuals, are generally more predominantly affected with OSA than females. Usually OSA is worse in REM sleep than in NREM sleep, although this is not always true...
  10. ncbi request reprint Clinically significant but unsuspected restless legs syndrome in patients with sleep apnea
    Sowmya Lakshminarayanan
    Center for Sleep Disorders, Treatment, Research and Education, New Jersey Neuroscience Institute at John F Kennedy Medical Center, Edison, New Jersey 08818, USA
    Mov Disord 20:501-3. 2005
    ..We have found the MEMO-NIH consensus conference questionnaire administered at the time of polysomnography to be useful in this regard...
  11. ncbi request reprint Rise of blood pressure with periodic limb movements in sleep and wakefulness
    Fouzia Siddiqui
    NJ Neuroscience Institute at JFK Medical Center, Seton Hall University School of Graduate Medical Education, Edison, NJ, USA
    Clin Neurophysiol 118:1923-30. 2007
    ..To measure changes in blood pressure and pulse rate associated with periodic limb movements in sleep (PLMS) in patients with restless legs syndrome (RLS)...
  12. ncbi request reprint Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST (RLS epidemiology, symptoms, and treatment) primary care study
    Wayne Hening
    Department of Neurology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ, USA
    Sleep Med 5:237-46. 2004
    ..To assess the frequency, impact, and medical response to the restless legs syndrome (RLS) in a large multi-national primary care population...
  13. ncbi request reprint The Johns Hopkins telephone diagnostic interview for the restless legs syndrome: preliminary investigation for validation in a multi-center patient and control population
    Wayne A Hening
    Department of Neurology, University of Medicine and Dentistry of New Jersey RW Johnson Medical School, New Brunswick, NJ, USA
    Sleep Med 4:137-41. 2003
    ..To develop and validate a telephone diagnostic interview (the Johns Hopkins telephone diagnostic interview for restless legs, abbreviated TDI) for diagnosis of the restless legs syndrome (RLS)...
  14. ncbi request reprint Restless legs syndrome prevalence and impact: REST general population study
    Richard P Allen
    Department of Neurology, The Johns Hopkins University, Baltimore, MD 21224, USA
    Arch Intern Med 165:1286-92. 2005
    ..Previous epidemiological studies, however, have failed to determine the prevalence of those with clinically significant RLS symptoms and to examine the life effects and medical experiences of this group...
  15. ncbi request reprint Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health
    Richard P Allen
    Department of Neurology, Sleep Medicine, Johns Hopkins Bayview Medical Center, Asthma and Allergy Building 1B46b, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    Sleep Med 4:101-19. 2003
    ..Modification of the criteria is now necessary to better reflect that increased body of knowledge, as well as to clarify slight confusion with the wording of the original criteria...
  16. ncbi request reprint Sweat artifact and respiratory artifact occurring simultaneously in polysomnogram
    Fouzia Siddiqui
    NJ Neuroscience Institute at JFK Medical Center, Seton Hall University School of Graduate Medical Education, 65 James Street, Edison, NJ 08818, USA
    Sleep Med 7:197-9. 2006
  17. doi request reprint Restless legs syndrome: a comprehensive overview on its epidemiology, risk factors, and treatment
    Paul Yeh
    Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Sleep Breath 16:987-1007. 2012
    ....
  18. pmc Effectiveness of treatment apnea-hypopnea index: a mathematical estimate of the true apnea-hypopnea index in the home setting
    Scott B Boyd
    Department of Oral and Maxillofacial Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232 2103, USA
    J Oral Maxillofac Surg 71:351-7. 2013
    ..To present a new measurement instrument, the Effectiveness of Treatment Apnea-Hypopnea Index (ET-AHI), which the authors developed to determine an estimate of the therapeutic control of obstructive sleep apnea (OSA)...
  19. ncbi request reprint Enhanced external counter pulsation (EECP) as a novel treatment for restless legs syndrome (RLS): a preliminary test of the vascular neurologic hypothesis for RLS
    Sri Sujanthy Rajaram
    Cardio Sleep Center, Old Bridge, Edison, NJ, USA
    Sleep Med 6:101-6. 2005
    ..We found some patients who underwent EECP for angina or congestive heart failure who also coincidentally had severe Restless Legs Syndrome (RLS). Case reports are presented...
  20. pmc Review of the relationship of restless legs syndrome and periodic limb movements in sleep to hypertension, heart disease, and stroke
    Arthur S Walters
    Department of Neurology, Vanderbilt University Medical Center, MCN A 0118, 1161 21st Ave South, Nashville, Tennessee 37232 2552, USA
    Sleep 32:589-97. 2009
    ..We cannot exclude the possibility that peripheral vascular, cardiovascular, and cerebrovascular disease may also contribute to RLS/PLMS, and mechanisms for these possibilities are also discussed...
  21. ncbi request reprint Does the endogenous opiate system play a role in the Restless Legs Syndrome? A pilot post-mortem study
    Arthur S Walters
    Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232 2551, USA
    J Neurol Sci 279:62-5. 2009
    ..In addition, other opioid rich areas need to be explored as well as areas implicated in the pathogenesis of RLS such as the red nucleus and raphe nucleus...
  22. ncbi request reprint Some children with growing pains may actually have restless legs syndrome
    Sri Sujanthy Rajaram
    New Jersey Neuroscience Institute at JFK Medical Center and Seton Hall University School of Graduate Medical Education, Edison, NJ, USA
    Sleep 27:767-73. 2004
    ..Those who met clinical criteria for RLS underwent polysomnography, and the results of their polysomnographic studies were compared to those of a control group (10 children, mean age 9.7 years)...
  23. doi request reprint Traditional Chinese medicine herbal preparations in restless legs syndrome (RLS) treatment: a review and probable first description of RLS in 1529
    Xue Yan
    Department of Neurology, Vanderbilt University School of Medicine, North A 0118, 1161 21st Ave South, Nashville, TN 37232 2551, USA
    Sleep Med Rev 16:509-18. 2012
    ..This review highlights aspects of Chinese herbal treatment important to guide future research and clinical practice. To our knowledge, this is the first systematic English review of the role of Chinese herbs in the treatment of RLS...
  24. pmc Review of the possible relationship and hypothetical links between attention deficit hyperactivity disorder (ADHD) and the simple sleep related movement disorders, parasomnias, hypersomnias, and circadian rhythm disorders
    Arthur S Walters
    New Jersey Neuroscience Institute at JFK Medical Center, Seton Hall University School of Graduate Medical Education, Edison, NJ, USA
    J Clin Sleep Med 4:591-600. 2008
    ..These relationships are reviewed and the implications for such associations are explored. Patients with sleep disorders should be queried about the symptoms of ADHD and vice versa...
  25. ncbi request reprint Restless legs symptoms in a patient with above knee amputations: a case of phantom restless legs
    Philip A Hanna
    New Jersey Neuroscience Institute, JFK Medical Center, Edison, NJ, USA
    Clin Neuropharmacol 27:87-9. 2004
    ..We propose expanding the spectrum of phantom limb phenomena to include phantom restless legs...
  26. ncbi request reprint The reliability, validity and responsiveness of the International Restless Legs Syndrome Study Group rating scale and subscales in a clinical-trial setting
    Linda Abetz
    Mapi Values, Adelphi Mill, Grimshaw Lane, Bollington, Cheshire SK10 5JB, UK
    Sleep Med 7:340-9. 2006
    ..0), using pooled data from two matching, placebo-controlled studies of ropinirole for treating Restless Legs Syndrome (RLS)...
  27. ncbi request reprint Symptoms of attention-deficit/hyperactivity disorder in adults with restless legs syndrome
    Mary L Wagner
    Rutgers, The State University of New Jersey, Ernest Mario School of Pharmacy, Piscataway 08854, USA
    Sleep 27:1499-504. 2004
    ..To determine the occurrence of symptoms of attention-deficit/hyperactivity disorder (ADHD) in adults with restless legs syndrome (RLS), normal controls, and controls with insomnia...
  28. ncbi request reprint An item response analysis of the international restless legs syndrome study group rating scale for restless legs syndrome
    Glen R Wunderlich
    Boehringer Ingelheim Canada Ltd, Burlington, Ont, Canada
    Sleep Med 6:131-9. 2005
    ..In order to further demonstrate the validity of the IRLS, the present study examined the relationship between scores on individual IRLS items and overall RLS severity...
  29. ncbi request reprint Restless legs syndrome: prevalence and impact in children and adolescents--the Peds REST study
    Daniel Picchietti
    University of Illinois School of Medicine and Carle Clinic Association, Department of Pediatrics, 602 W University Ave, Urbana, IL 61801, USA
    Pediatrics 120:253-66. 2007
    ..In this first population-based study to use specific pediatric diagnostic criteria, we examined the prevalence and impact of restless legs syndrome in 2 age groups: 8 to 11 and 12 to 17 years...
  30. ncbi request reprint The restless legs syndrome
    Claudia Trenkwalder
    Paracelsus Elena Klinik, Centre of Parkinsonism and Movement Disorders, Kassel, Germany
    Lancet Neurol 4:465-75. 2005
    ..Various other drugs, such as opioids, gabapentin, and benzodiazepines, provide alternative treatment possibilities...
  31. ncbi request reprint Restless legs syndrome: confirmation of linkage to chromosome 12q, genetic heterogeneity, and evidence of complexity
    Alex Desautels
    Centre d Etude du Sommeil, Hopital du Sacre Coeur de Montreal, Canada
    Arch Neurol 62:591-6. 2005
    ..Genes are involved in the etiology of restless legs syndrome, a common sensorimotor disorder...
  32. ncbi request reprint Enhanced external counter pulsation (EECP) for restless legs syndrome (RLS): preliminary negative results in a parallel double-blind study
    Sri Sujanthy Rajaram
    Sleep Med 7:390-1. 2006
  33. ncbi request reprint No significant difference in cytokine levels in patients with restless legs syndrome versus controls - preliminary data
    Fouzia Siddiqui
    Sleep Med 8:98-9. 2007
  34. ncbi request reprint Definition of restless legs syndrome, how to diagnose it, and how to differentiate it from RLS mimics
    Heike Benes
    Somni Bene Institute for Medical Research and Sleep Medicine, Schwerin, Germany
    Mov Disord 22:S401-8. 2007
    ..Standardized methods to assess a RLS diagnosis are presented which might improve differential diagnosis and in general the reliability and validity of RLS diagnosis...
  35. ncbi request reprint A preliminary look at the percentage of patients with Restless Legs Syndrome who also have Parkinson Disease, Essential Tremor or Tourette Syndrome in a single practice
    Arthur S Walters
    J Sleep Res 12:343-5. 2003
  36. ncbi request reprint The scoring of arousal in sleep: reliability, validity, and alternatives
    Michael H Bonnet
    Dayton Department of Veterans Affairs Medical Center, OH 45428, USA
    J Clin Sleep Med 3:133-45. 2007
    ..Additional refinement of arousal scoring will provide improved insight into sleep pathology and recovery...
  37. ncbi request reprint Magnesium not likely to play a major role in the pathogenesis of Restless Legs Syndrome: serum and cerebrospinal fluid studies
    Arthur S Walters
    Sleep Med 8:186-7. 2007