Michael Walsh

Summary

Publications

  1. ncbi request reprint Relationship between intraoperative mean arterial pressure and clinical outcomes after noncardiac surgery: toward an empirical definition of hypotension
    Michael Walsh
    Departments of Medicine, and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Anesthesiology 119:507-15. 2013
  2. doi request reprint Long-term follow-up of patients with severe ANCA-associated vasculitis comparing plasma exchange to intravenous methylprednisolone treatment is unclear
    Michael Walsh
    Department of Medicine Nephrology, St Joseph s Hospital, McMaster University, Hamilton, Ontario, Canada
    Kidney Int 84:397-402. 2013
  3. doi request reprint Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis with poor kidney function: a subgroup analysis of the Aspreva Lupus Management Study
    Michael Walsh
    Department of Medicine Nephrology, McMaster University, Hamilton, Canada
    Am J Kidney Dis 61:710-5. 2013
  4. pmc Plasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial
    Michael Walsh
    Departments of Medicine and Clinical Epidemiology and Biostatistics, Marian Wing, Division of Nephrology, McMaster University, St, Joseph s Hospital, 50 Charlton Ave East, Hamilton, ON L8S 4A6, Canada
    Trials 14:73. 2013
  5. pmc Plasma exchange for renal vasculitis and idiopathic rapidly progressive glomerulonephritis: a meta-analysis
    Michael Walsh
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada
    Am J Kidney Dis 57:566-74. 2011
  6. ncbi request reprint Risk factors for relapse of antineutrophil cytoplasmic antibody-associated vasculitis
    Michael Walsh
    Division of Nephrology, St Joseph s Hospital, Hamilton, Ontario, Canada
    Arthritis Rheum 64:542-8. 2012
  7. ncbi request reprint Kidney function after off-pump or on-pump coronary artery bypass graft surgery: a randomized clinical trial
    Amit X Garg
    Division of Nephrology, Department of Medicine, Western University, London, Ontario, Canada2Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada3Department of Clinical Epidemiology and Biostatistics, McMaster Universit
    JAMA 311:2191-8. 2014
  8. pmc Assessment and implication of prognostic imbalance in randomized controlled trials with a binary outcome--a simulation study
    Rong Chu
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 7:e36677. 2012
  9. pmc Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 7:e39471. 2012
  10. pmc Association between angiotensin converting enzyme inhibitor or angiotensin receptor blocker use prior to major elective surgery and the risk of acute dialysis
    Mitesh Shah
    Division of Nephrology, Department of Medicine, Western University, London, Canada
    BMC Nephrol 15:53. 2014

Detail Information

Publications24

  1. ncbi request reprint Relationship between intraoperative mean arterial pressure and clinical outcomes after noncardiac surgery: toward an empirical definition of hypotension
    Michael Walsh
    Departments of Medicine, and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Anesthesiology 119:507-15. 2013
    ..The authors evaluated the association between the intraoperative mean arterial pressure (MAP) and the risk of AKI and myocardial injury...
  2. doi request reprint Long-term follow-up of patients with severe ANCA-associated vasculitis comparing plasma exchange to intravenous methylprednisolone treatment is unclear
    Michael Walsh
    Department of Medicine Nephrology, St Joseph s Hospital, McMaster University, Hamilton, Ontario, Canada
    Kidney Int 84:397-402. 2013
    ..Further research is required to determine the role of PLEX in AAV. Given the poor outcomes of patients with severe AAV, improved treatment is urgently needed...
  3. doi request reprint Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis with poor kidney function: a subgroup analysis of the Aspreva Lupus Management Study
    Michael Walsh
    Department of Medicine Nephrology, McMaster University, Hamilton, Canada
    Am J Kidney Dis 61:710-5. 2013
    ..Mycophenolate mofetil (MMF) frequently is used as an alternative to intravenous cyclophosphamide to treat lupus nephritis. Whether MMF is adequate for patients with severely decreased kidney function at the time of treatment is uncertain...
  4. pmc Plasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial
    Michael Walsh
    Departments of Medicine and Clinical Epidemiology and Biostatistics, Marian Wing, Division of Nephrology, McMaster University, St, Joseph s Hospital, 50 Charlton Ave East, Hamilton, ON L8S 4A6, Canada
    Trials 14:73. 2013
    ..A randomized study of both plasma exchange and glucocorticoids is required to evaluate plasma exchange and oral glucocorticoid dosing in patients with AAV...
  5. pmc Plasma exchange for renal vasculitis and idiopathic rapidly progressive glomerulonephritis: a meta-analysis
    Michael Walsh
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada
    Am J Kidney Dis 57:566-74. 2011
    ..Plasma exchange may be effective adjunctive treatment for renal vasculitis. We performed a systematic review and meta-analysis of randomized controlled trials of plasma exchange for renal vasculitis...
  6. ncbi request reprint Risk factors for relapse of antineutrophil cytoplasmic antibody-associated vasculitis
    Michael Walsh
    Division of Nephrology, St Joseph s Hospital, Hamilton, Ontario, Canada
    Arthritis Rheum 64:542-8. 2012
    ..To determine the association between characteristics at diagnosis and the time to first relapse in a large cohort of patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV)...
  7. ncbi request reprint Kidney function after off-pump or on-pump coronary artery bypass graft surgery: a randomized clinical trial
    Amit X Garg
    Division of Nephrology, Department of Medicine, Western University, London, Ontario, Canada2Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada3Department of Clinical Epidemiology and Biostatistics, McMaster Universit
    JAMA 311:2191-8. 2014
    ..Such acute kidney injury is associated with lower long-term kidney function. However, it has not been demonstrated that an intervention that reduces the risk of such acute kidney injury better preserves long-term kidney function...
  8. pmc Assessment and implication of prognostic imbalance in randomized controlled trials with a binary outcome--a simulation study
    Rong Chu
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 7:e36677. 2012
    ....
  9. pmc Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 7:e39471. 2012
    ..However, no previous studies have explored how many trials and events are required to ensure stable and reliable I(2) estimates, or how 95% CIs perform as evidence accumulates...
  10. pmc Association between angiotensin converting enzyme inhibitor or angiotensin receptor blocker use prior to major elective surgery and the risk of acute dialysis
    Mitesh Shah
    Division of Nephrology, Department of Medicine, Western University, London, Canada
    BMC Nephrol 15:53. 2014
    ..Some studies but not others suggest angiotensin converting enzyme inhibitor (ACEi) or angiotensin receptor blocker (ARB) use prior to major surgery associates with a higher risk of postoperative acute kidney injury (AKI) and death...
  11. doi request reprint The association between perioperative hemoglobin and acute kidney injury in patients having noncardiac surgery
    Michael Walsh
    Division of Nephrology, McMaster University, St Joseph s Hospital, 50 Charlton Ave, E Hamilton, ON L8S 4A6
    Anesth Analg 117:924-31. 2013
    ..We studied hemoglobin concentration before and 24 hours after surgery and its association with AKI...
  12. ncbi request reprint The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index
    Michael Walsh
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada, L8S4L8 Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada, L8S4L8 Population Health Research Institute, Hamilton Health Sciences and McMaster University, 237 Barton St East, Hamilton, Ontario, Canada, L8L2X2 Electronic address
    J Clin Epidemiol 67:622-8. 2014
    ..A P-value <0.05 is one metric used to evaluate the results of a randomized controlled trial (RCT). We wondered how often statistically significant results in RCTs may be lost with small changes in the numbers of outcomes...
  13. pmc The number of patients and events required to limit the risk of overestimation of intervention effects in meta-analysis--a simulation study
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada
    PLoS ONE 6:e25491. 2011
    ..It has been suggested that surpassing the optimal information size (i.e., the required meta-analysis sample size) provides sufficient protection against overestimation due to random error, but this claim has not yet been validated...
  14. pmc Coronary Artery Bypass Grafting Surgery Off- or On-pump Revascularisation Study (CORONARY): kidney substudy analytic protocol of an international randomised controlled trial
    Amit X Garg
    Division of Nephrology, Department of Medicine, Western University, London, Canada
    BMJ Open 2:e001080. 2012
    ..This collection began for patients enrolled after 1 January 2010. Remaining 1-year renal outcome data will be collected throughout 2012. Results will be reported in 2013. CLINICAL TRIAL REGISTRATION NUMBER: NCT 00463294...
  15. doi request reprint Effects of perioperative blood product use on surgical site infection following thoracic and lumbar spinal surgery
    Ran Schwarzkopf
    Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY, USA
    Spine (Phila Pa 1976) 35:340-6. 2010
    ..Retrospective case-control review...
  16. ncbi request reprint Warfarin-induced sublingual hematoma mimicking Ludwig angina: Conservative management of a potentially life-threatening condition
    Emma Cashman
    Department of Otolaryngology, Waterford Regional Hospital, Dunmore Rd, Waterford, Co Waterford 051 873321, Ireland
    Ear Nose Throat J 90:E1. 2011
    ..We report a case of sublingual hematoma that was treated conservatively, and we discuss the presentation and management of this entity...
  17. doi request reprint The predictive power of preoperative hip range of motion for the development of heterotopic ossification
    Ran Schwarzkopf
    Department of Orthopedic Surgery, NYU Hospital for Joint Diseases, New York, New York, USA
    Orthopedics 34:169. 2011
    ..Surgeons should consider this data when considering the use of prophylactic treatment to avoid the development of heterotopic ossification...
  18. ncbi request reprint Quantitative EEG indices of sub-acute ischaemic stroke correlate with clinical outcomes
    Simon P Finnigan
    Centre for Magnetic Resonance, The University of Queensland, Brisbane, Australia
    Clin Neurophysiol 118:2525-32. 2007
    ..QEEG indices and National Institutes of Health Stroke Scale (NIHSS) scores were compared...
  19. doi request reprint Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes
    Fernando Botto
    From the Hamilton General Hospital, David Braley Cardiac, Vascular, and Stroke Research Institute, Population Health Research Institute, Hamilton, Ontario, Canada P J D and Members of The VISION Writing Group and VISION Investigators, who are listed in appendix 1 and appendix 2, respectively Population Health Research Institute, Hamilton, Ontario, Canada Department of Clinical Research, Estudios Clinicos Latino America ECLA, Rosario, Argentina Biomedical Research Institute Sant Pau IIB Sant Pau, Barcelona, Spain The Chinese University of Hong Kong, Shatin, N T, Hong Kong Universidad Autónoma de Bucaramanga and Fundación Cardioinfantil, Colombia St John s Medical College and Research Institute, Bangalore, India Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada Department of Clinical Epidemiology and Biostatistics and Department of Medicine, McMaster University, Hamilton, Ontario, Canada Hospital General Universitario Gregorio Maranon, Madrid, Spain University of Alberta, Edmonton, Alberta, Canada University of Malaya, Kuala Lampur, Malaysia Research Institute Hcor Hospital do Coracao, Sao Paulo, Brazil Barts and The London School of Medicine and Dentistry
    Anesthesiology 120:564-78. 2014
    ..The study's four objectives were to determine the diagnostic criteria, characteristics, predictors, and 30-day outcomes of MINS...
  20. pmc Histopathologic features aid in predicting risk for progression of IgA nephropathy
    Michael Walsh
    Division of Nephrology, Foothills Medical Centre, Calgary, AB, T2N 0L9, Canada
    Clin J Am Soc Nephrol 5:425-30. 2010
    ..Accurately identifying patients who are at risk for progressive disease is challenging. The extent to which histopathologic features improves prognostication is uncertain...
  21. doi request reprint The risk of perioperative bleeding in patients with chronic kidney disease: a systematic review and meta-analysis
    Rey R Acedillo
    Division of Nephrology, Department of Medicine, Western University, London, Canada Department of Epidemiology and Biostatistics, Western University, London, Canada Department of Medicine, McMaster University, Hamilton, Canada Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    Ann Surg 258:901-13. 2013
    ..We conducted a systematic review and meta-analysis to summarize existing information and quantify the risk of perioperative bleeding from chronic kidney disease...
  22. pmc Estimated GFR reporting influences recommendations for dialysis initiation
    K Scott Brimble
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    J Am Soc Nephrol 24:1737-42. 2013
    ..03). These results indicate that eGFR reporting modestly increases the likelihood that dialysis is recommended, and physicians should be aware of this effect when assessing patients with severe CKD. ..
  23. pmc Health-related quality of life in patients with newly diagnosed antineutrophil cytoplasmic antibody-associated vasculitis
    Michael Walsh
    McMaster University, Hamilton, Ontario, Canada
    Arthritis Care Res (Hoboken) 63:1055-61. 2011
    ..Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) can present with a broad spectrum of signs and symptoms. The relative effects of different manifestations on health-related quality of life (HRQOL) are unknown...
  24. pmc Statin use associates with a lower incidence of acute kidney injury after major elective surgery
    Amber O Molnar
    Division of Nephrology, Department of Medicine, University of Western Ontario, London, Canada
    J Am Soc Nephrol 22:939-46. 2011
    ..79; 95% CI, 0.74 to 0.85). Propensity score matching produced similar results. These data suggest that statins may protect against renal complications after major elective surgery and reduce perioperative mortality...