James K Walsh

Summary

Publications

  1. doi request reprint Treatment of elderly primary insomnia patients with EVT 201 improves sleep initiation, sleep maintenance, and daytime sleepiness
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, 232 S Woods Mill Road, Chesterfield, MO 63017, United States
    Sleep Med 11:23-30. 2010
  2. doi request reprint The partial positive allosteric GABA(A) receptor modulator EVT 201 is efficacious and safe in the treatment of adult primary insomnia patients
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, 232 S Woods Mill Road, Chesterfield, MO 63017, USA
    Sleep Med 10:859-64. 2009
  3. pmc Enhancing slow wave sleep with sodium oxybate reduces the behavioral and physiological impact of sleep loss
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, Chesterfield, MO 63017, USA
    Sleep 33:1217-25. 2010
  4. doi request reprint A convenient expiratory positive airway pressure nasal device for the treatment of sleep apnea in patients non-adherent with continuous positive airway pressure
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, 232 S Woods Mill Rd, Chesterfield, MO, USA
    Sleep Med 12:147-52. 2011
  5. pmc Slow wave sleep enhancement with gaboxadol reduces daytime sleepiness during sleep restriction
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center St Luke s Hospital, St Louis, MO, USA
    Sleep 31:659-72. 2008
  6. ncbi request reprint Tiagabine is associated with sustained attention during sleep restriction: evidence for the value of slow-wave sleep enhancement?
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center St Luke s Hospital, St Louis, MO, USA
    Sleep 29:433-43. 2006
  7. ncbi request reprint Dose-response effects of tiagabine on the sleep of older adults
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center, St Luke s Hospital, St Louis, MO, USA
    Sleep 28:673-6. 2005
  8. ncbi request reprint Tiagabine increases slow-wave sleep in a dose-dependent fashion without affecting traditional efficacy measures in adults with primary insomnia
    James K Walsh
    Sleep Medicine and Research Center, St Johnś St Lukeś Hospitals, St Louis, MO 63017, USA
    J Clin Sleep Med 2:35-41. 2006
  9. ncbi request reprint The selective extrasynaptic GABAA agonist, gaboxadol, improves traditional hypnotic efficacy measures and enhances slow wave activity in a model of transient insomnia
    James K Walsh
    St Johns Hospital, St Louis, MO, USA
    Sleep 30:593-602. 2007
  10. doi request reprint Efficacy and safety of zolpidem extended release in elderly primary insomnia patients
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy and St Luke s Hospitals, 232 S Woods Hill Road, Chesterfield, MO 63017, USA
    Am J Geriatr Psychiatry 16:44-57. 2008

Collaborators

Detail Information

Publications23

  1. doi request reprint Treatment of elderly primary insomnia patients with EVT 201 improves sleep initiation, sleep maintenance, and daytime sleepiness
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, 232 S Woods Mill Road, Chesterfield, MO 63017, United States
    Sleep Med 11:23-30. 2010
    ..Two doses of EVT 201, a partial positive allosteric modulator of the GABA(A) system, were evaluated in elderly primary insomnia patients with daytime sleepiness...
  2. doi request reprint The partial positive allosteric GABA(A) receptor modulator EVT 201 is efficacious and safe in the treatment of adult primary insomnia patients
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, 232 S Woods Mill Road, Chesterfield, MO 63017, USA
    Sleep Med 10:859-64. 2009
    ..To evaluate polysomnographic (PSG) and self-reported measures of the efficacy and safety of EVT 201 in patients with primary insomnia...
  3. pmc Enhancing slow wave sleep with sodium oxybate reduces the behavioral and physiological impact of sleep loss
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, Chesterfield, MO 63017, USA
    Sleep 33:1217-25. 2010
    ..To investigate whether enhancement of slow wave sleep (SWS) with sodium oxybate reduces the impact of sleep deprivation...
  4. doi request reprint A convenient expiratory positive airway pressure nasal device for the treatment of sleep apnea in patients non-adherent with continuous positive airway pressure
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, 232 S Woods Mill Rd, Chesterfield, MO, USA
    Sleep Med 12:147-52. 2011
    ..The short-term efficacy of and adherence with a convenient expiratory positive airway pressure (EPAP) nasal device was evaluated in OSA patients non-adherent with CPAP...
  5. pmc Slow wave sleep enhancement with gaboxadol reduces daytime sleepiness during sleep restriction
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center St Luke s Hospital, St Louis, MO, USA
    Sleep 31:659-72. 2008
    ..To evaluate the impact of enhanced slow wave sleep (SWS) on behavioral, psychological, and physiological changes resulting from sleep restriction...
  6. ncbi request reprint Tiagabine is associated with sustained attention during sleep restriction: evidence for the value of slow-wave sleep enhancement?
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center St Luke s Hospital, St Louis, MO, USA
    Sleep 29:433-43. 2006
    ..To evaluate the impact of enhanced slow-wave sleep (SWS) on behavioral, psychological, and physiologic changes resulting from sleep restriction..
  7. ncbi request reprint Dose-response effects of tiagabine on the sleep of older adults
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy Medical Center, St Luke s Hospital, St Louis, MO, USA
    Sleep 28:673-6. 2005
    ..To evaluate the dose- response effects of tiagabine on sleep and safety measures in healthy older adults...
  8. ncbi request reprint Tiagabine increases slow-wave sleep in a dose-dependent fashion without affecting traditional efficacy measures in adults with primary insomnia
    James K Walsh
    Sleep Medicine and Research Center, St Johnś St Lukeś Hospitals, St Louis, MO 63017, USA
    J Clin Sleep Med 2:35-41. 2006
    ..This study evaluated dose-response effects of tiagabine on sleep in adults with primary insomnia...
  9. ncbi request reprint The selective extrasynaptic GABAA agonist, gaboxadol, improves traditional hypnotic efficacy measures and enhances slow wave activity in a model of transient insomnia
    James K Walsh
    St Johns Hospital, St Louis, MO, USA
    Sleep 30:593-602. 2007
    ..Evaluate the hypnotic efficacy of gaboxadol, a selective extrasynaptic GABAA agonist (SEGA), in a phase advance model of transient insomnia...
  10. doi request reprint Efficacy and safety of zolpidem extended release in elderly primary insomnia patients
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy and St Luke s Hospitals, 232 S Woods Hill Road, Chesterfield, MO 63017, USA
    Am J Geriatr Psychiatry 16:44-57. 2008
    ..To evaluate the clinical efficacy and safety of zolpidem extended release for the treatment of primary insomnia in elderly patients...
  11. pmc Nightly treatment of primary insomnia with eszopiclone for six months: effect on sleep, quality of life, and work limitations
    James K Walsh
    Sleep Medicine and Research Center, St John s St Luke s Hospitals and the Department of Psychology, Saint Louis University, St Louis, MO 63017, USA
    Sleep 30:959-68. 2007
    ..To evaluate 6 months' eszopiclone treatment upon patient-reported sleep, fatigue and sleepiness, insomnia severity, quality of life, and work limitations...
  12. ncbi request reprint Tiagabine enhances slow wave sleep and sleep maintenance in primary insomnia
    James K Walsh
    St John s Mercy St Luke s Hospitals, Sleep Medicine and Research Center, Chesterfield, MO 63017, and Department of Psychology, St Louis University, St Louis, MO 63130, USA
    Sleep Med 7:155-61. 2006
    ..To evaluate the effect of tiagabine on sleep and next-morning alertness and performance in adult patients with primary insomnia...
  13. ncbi request reprint Modafinil improves alertness, vigilance, and executive function during simulated night shifts
    James K Walsh
    Sleep Medicine and Research Center, affiliated with St John s Mercy Medical Center and St Luke s Hospital, St Louis, Missouri, USA
    Sleep 27:434-9. 2004
    ..To assess the effect of 200 mg of modafinil compared to placebo on alertness, neurobehavioral performance, and executive function during 4 consecutive simulated night shifts...
  14. ncbi request reprint Efficacy of the selective extrasynaptic GABA A agonist, gaboxadol, in a model of transient insomnia: a randomized, controlled clinical trial
    James K Walsh
    St John s Hospital, St Louis, MO, USA
    Sleep Med 9:393-402. 2008
    ..The hypnotic efficacy of gaboxadol, a selective extrasynaptic GABA A agonist (SEGA), was evaluated in a phase-advance model of transient insomnia...
  15. ncbi request reprint Pharmacologic management of insomnia
    James K Walsh
    Sleep Medicine and Research Center, St John s Mercy and St Luke s Hospitals, Department of Psychiatry, Saint Louis University, St Louis, MO, USA
    J Clin Psychiatry 65:41-5. 2004
    ..Sedating antidepressants are also frequently prescribed to promote sleep despite inadequate data to support their efficacy for this indication and a greater potential for clinically troublesome side effects...
  16. ncbi request reprint Efficacy and tolerability of indiplon in older adults with primary insomnia
    James K Walsh
    Sleep Medicine and Research Center, St John s St Luke s Hospitals, 232 S Woods Mill Road, Chesterfield, St Louis, MO 63017, USA
    Sleep Med 8:753-9. 2007
    ..To evaluate the efficacy and safety of indiplon in elderly patients with primary insomnia...
  17. pmc Nighttime insomnia symptoms and perceived health in the America Insomnia Survey (AIS)
    James K Walsh
    Sleep Medicine and Research Center, St Luke s Hospital, St Louis, MO, USA
    Sleep 34:997-1011. 2011
    ....
  18. ncbi request reprint Pharmacologic management of insomnia: past, present, and future
    Denise Troy Curry
    Sleep Medicine and Research Center, St John s Mercy Medical Center and St Luke s Hospital, Chesterfield, MO 63017, USA
    Psychiatr Clin North Am 29:871-93; abstract vii-viii. 2006
    ..Improvement in managing insomnia will result from systematic research with these drugs, with drugs in development, and with novel uses, such as co-therapy...
  19. doi request reprint The effect of two benzodiazepine receptor agonist hypnotics on sleep-dependent memory consolidation
    Janine M Hall-Porter
    Sleep Medicine and Research Center, St Luke s Hospital, Chesterfield, MO
    J Clin Sleep Med 10:27-34. 2014
    ....
  20. ncbi request reprint Understanding GABA and its relation to insomnia and therapeutics
    James K Walsh
    Sleep Medicine and Research Center, St John K St Luke s Hospitals, Department of Psychology, Saint Louis University, St Louis, MO, USA
    J Clin Sleep Med 2:S5-6. 2006
  21. ncbi request reprint Clinical and socioeconomic correlates of insomnia
    James K Walsh
    Sleep Medicine and Research Center at St Luke s Hospital, Chesterfield, MO, USA
    J Clin Psychiatry 65:13-9. 2004
    ..Chronic insomnia is a common problem, often associated with negative waking mood or function. As such, heightened clinical attention and clinical research appear warranted...
  22. ncbi request reprint Zolpidem "as needed" for the treatment of primary insomnia: a double-blind, placebo-controlled study
    James K Walsh
    Sleep Medicine Research Center, St Luke s Hospital, Chesterfield, Missouri 63017, USA
    Sleep Med Rev 6:S7-10; discussion S10-1, S31-3. 2002
  23. doi request reprint Strategies for de-identification and anonymization of electronic health record data for use in multicenter research studies
    Clete A Kushida
    Stanford Sleep Medicine Center, Redwood City, CA 94063 5704, USA
    Med Care 50:S82-101. 2012
    ..The use of these strategies in multicenter research studies is paramount in importance, given the need to share electronic health record data across multiple environments and institutions while safeguarding patient privacy...