Patrick D Walker

Summary

Publications

  1. ncbi request reprint Dense deposit disease is not a membranoproliferative glomerulonephritis
    Patrick D Walker
    Nephropathology Associates, Little Rock, AR 72211, USA
    Mod Pathol 20:605-16. 2007
  2. ncbi request reprint Dense deposit disease: new insights
    Patrick D Walker
    Nephropathology Associates, Little Rock, Akansas 72211, USA
    Curr Opin Nephrol Hypertens 16:204-12. 2007
  3. doi request reprint The renal biopsy
    Patrick D Walker
    Nephropathology Associates, 10810 Executive Center Drive, Little Rock, AR 72211, USA
    Arch Pathol Lab Med 133:181-8. 2009
  4. ncbi request reprint Practice guidelines for the renal biopsy
    Patrick D Walker
    Nephropathology Associates, Little Rock, AR 72211, USA
    Mod Pathol 17:1555-63. 2004
  5. ncbi request reprint Membranous-like glomerulopathy with masked IgG kappa deposits
    Christopher P Larsen
    NephroPath, Little Rock, Arkansas, USA
    Kidney Int 86:154-61. 2014
  6. doi request reprint The morphologic spectrum and clinical significance of light chain proximal tubulopathy with and without crystal formation
    Christopher P Larsen
    Nephropathology Associates, Little Rock, AR 72211, USA
    Mod Pathol 24:1462-9. 2011
  7. ncbi request reprint Phospholipase A2 receptor staining in pediatric idiopathic membranous glomerulopathy
    L Nicholas Cossey
    NephroPath, 10810 Executive Center Dr Suite 100, Little Rock, AR, 72211, USA
    Pediatr Nephrol 28:2307-11. 2013
  8. doi request reprint Renal medullary angiitis: a case series from a single institution
    Allen R Hendricks
    NephroPath, Little Rock, AR 72211, USA
    Hum Pathol 44:521-5. 2013
  9. doi request reprint The incidence of atubular glomeruli in nephropathic cystinosis renal biopsies
    Christopher P Larsen
    Nephropathology Associates, Little Rock, AR 72211, USA
    Mol Genet Metab 101:417-20. 2010
  10. doi request reprint Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor staining in renal biopsies
    Christopher P Larsen
    NephroPath, Nephropathology Associates, Little Rock, AR 72211, USA
    Mod Pathol 26:709-15. 2013

Research Grants

  1. Predicting Nephropathy in Type II Diabetes
    Patrick Walker; Fiscal Year: 2005

Detail Information

Publications24

  1. ncbi request reprint Dense deposit disease is not a membranoproliferative glomerulonephritis
    Patrick D Walker
    Nephropathology Associates, Little Rock, AR 72211, USA
    Mod Pathol 20:605-16. 2007
    ..Therefore, dense deposit disease should no longer be regarded as a subtype of membranoproliferative glomerulonephritis...
  2. ncbi request reprint Dense deposit disease: new insights
    Patrick D Walker
    Nephropathology Associates, Little Rock, Akansas 72211, USA
    Curr Opin Nephrol Hypertens 16:204-12. 2007
    ....
  3. doi request reprint The renal biopsy
    Patrick D Walker
    Nephropathology Associates, 10810 Executive Center Drive, Little Rock, AR 72211, USA
    Arch Pathol Lab Med 133:181-8. 2009
    ..Correct fixation and processing of renal biopsy tissue is critical, and the laboratory must be skilled with renal biopsy light microscopy, immunohistochemistry, and transmission electron microscopy preparation...
  4. ncbi request reprint Practice guidelines for the renal biopsy
    Patrick D Walker
    Nephropathology Associates, Little Rock, AR 72211, USA
    Mod Pathol 17:1555-63. 2004
    ..This document incorporates the consensus opinions of the committee and the RPS membership at large...
  5. ncbi request reprint Membranous-like glomerulopathy with masked IgG kappa deposits
    Christopher P Larsen
    NephroPath, Little Rock, Arkansas, USA
    Kidney Int 86:154-61. 2014
    ..We have termed this unique form of glomerulopathy membranous-like glomerulopathy with masked IgG-κ deposits. ..
  6. doi request reprint The morphologic spectrum and clinical significance of light chain proximal tubulopathy with and without crystal formation
    Christopher P Larsen
    Nephropathology Associates, Little Rock, AR 72211, USA
    Mod Pathol 24:1462-9. 2011
    ..And given that it is often associated with previously unrecognized myeloma, it is a critically important diagnosis...
  7. ncbi request reprint Phospholipase A2 receptor staining in pediatric idiopathic membranous glomerulopathy
    L Nicholas Cossey
    NephroPath, 10810 Executive Center Dr Suite 100, Little Rock, AR, 72211, USA
    Pediatr Nephrol 28:2307-11. 2013
    ..To our knowledge, this is the largest study of its kind to assess PLA2R staining in a pediatric population...
  8. doi request reprint Renal medullary angiitis: a case series from a single institution
    Allen R Hendricks
    NephroPath, Little Rock, AR 72211, USA
    Hum Pathol 44:521-5. 2013
    ..It is an important lesion to recognize as it frequently suggests the presence of a systemic vasculitis and could be mistaken for interstitial nephritis...
  9. doi request reprint The incidence of atubular glomeruli in nephropathic cystinosis renal biopsies
    Christopher P Larsen
    Nephropathology Associates, Little Rock, AR 72211, USA
    Mol Genet Metab 101:417-20. 2010
    ..The process is consistent with the previously reported increased apoptosis in renal tubule cells due to lysosomal cystine storage...
  10. doi request reprint Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor staining in renal biopsies
    Christopher P Larsen
    NephroPath, Nephropathology Associates, Little Rock, AR 72211, USA
    Mod Pathol 26:709-15. 2013
    ..We present the largest case series to date examining PLA2R1 involvement in membranous glomerulopathy utilizing a technique that is readily adoptable by most renal pathology laboratories...
  11. ncbi request reprint Clinical quiz. A patient with hyperuricemia and renal failure
    Tonya Williams
    Department of Pediatrics, Arkansas Children s Hospital, Little Rock, AR, 72202, USA
    Pediatr Nephrol 22:948-53. 2007
  12. doi request reprint Prevalence and morphology of leukocyte chemotactic factor 2-associated amyloid in renal biopsies
    Christopher P Larsen
    Nephropathology Associates, Little Rock, Arkansas 72211, USA
    Kidney Int 77:816-9. 2010
    ..Hence, we believe that ALECT2 represents the third common form of renal amyloidosis...
  13. pmc Apolipoprotein L1 risk variants associate with systemic lupus erythematosus-associated collapsing glomerulopathy
    Christopher P Larsen
    NephroPath, 10810 Executive Center Drive, Suite 100, Little Rock, AR 72211, USA
    J Am Soc Nephrol 24:722-5. 2013
    ..001). In conclusion, APOL1 genotyping of African-American patients with SLE might help identify patients at risk for collapsing glomerulopathy, an entity with a poor prognosis that is often resistant to treatment...
  14. ncbi request reprint Renal biopsy in patients aged 80 years and older
    Ramesh Nair
    Nephropathology Associates, Little Rock, AR 72211, USA
    Am J Kidney Dis 44:618-26. 2004
    ..Recently, we noted an increase in renal biopsies among patients 80 years and older. This is a demographic subset with little or no previously reported clinicopathologic correlation between renal biopsy findings and clinical syndromes...
  15. ncbi request reprint SLE: the great imitator strikes again
    Jane M Bell
    Nephropathology Associates, Little Rock, AR 72211, USA
    Am J Kidney Dis 45:219-22. 2005
  16. ncbi request reprint Infection in renal transplantation: a case of acute Q fever
    Christopher P Larsen
    University of Arkansas for Medical Sciences, NephroPath, Little Rock, AR 72211, USA
    Am J Kidney Dis 48:321-6. 2006
    ....
  17. pmc The histopathologic spectrum of kidney biopsies in patients with inflammatory bowel disease
    Josephine M Ambruzs
    NephroPath, Little Rock, Arkansas, Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas
    Clin J Am Soc Nephrol 9:265-70. 2014
    ..This study aimed to evaluate a large series of kidney biopsy specimens from patients with IBD to better define the spectrum and relative frequencies of IBD-associated kidney pathology...
  18. doi request reprint Phospholipase A2 receptor (PLA2R) staining is useful in the determination of de novo versus recurrent membranous glomerulopathy
    Christopher P Larsen
    NephroPath, 10810 Executive Center Drive, Suite 100 Little Rock, AR 72211, USA
    Transplantation 95:1259-62. 2013
    ..We sought to determine the utility of phospholipase A2 receptor (PLA2R) staining for the detection of recurrent MG. We also evaluated for increased evidence of antibody-mediated rejection in the de novo group, as some have reported...
  19. ncbi request reprint Morphologic manifestations of combined light-chain deposition disease and light-chain cast nephropathy
    Neriman Gokden
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Ultrastruct Pathol 31:141-9. 2007
    ..There were minimal or no glomerular changes by LM. This study shows the lack of characteristic LM findings of LCDD in combined cases of LCDD and LCCN and emphasizes the difficulty for-definitive diagnosis-without IF and EM...
  20. ncbi request reprint Podocyte injury associated glomerulopathies induced by pamidronate
    Yousri M Barri
    Department of Medicine Nephrology and Multiple Myeloma Unit, The University of Arkansas for Medical Sciences and the Central Arkansas Veterans Healthcare System, Little Rock, Arkansas, USA
    Kidney Int 65:634-41. 2004
    ..This has led to its use in supportive and maintenance therapy of myeloma in conjunction with steroids and chemotherapy. It has also been selectively used in patients with breast cancer and other neoplasms...
  21. ncbi request reprint Meprin, a brush-border enzyme, plays an important role in hypoxic/ischemic acute renal tubular injury in rats
    Simone Carmago
    Department of Pathology, Central Arkansas Veterans Healthcare System and the University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72205, USA
    Kidney Int 61:959-66. 2002
    ..The second objective was to determine if inhibition of meprin is protective against hypoxia-reoxygenation injury in vitro and ischemia-reperfusion injury in vivo...
  22. ncbi request reprint Renal pathology in the pediatric transplant patient
    Carole Vogler
    Department of Pathology, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Adv Anat Pathol 14:202-16. 2007
    ..Here, we describe the pathology of the more common morphologic lesions in kidneys of children with a renal allograft...
  23. ncbi request reprint New approaches to the treatment of dense deposit disease
    Richard J H Smith
    Department of Internal Medicine and Otolaryngology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
    J Am Soc Nephrol 18:2447-56. 2007
    ..As the understanding of DDD increases, novel therapies should be integrated into existing protocols for DDD and evaluated using an open-label Bayesian study design...
  24. ncbi request reprint Rapidly progressive renal failure in childhood
    Jeffrey C Hoschek
    Department of Medicine, University of Illinois College of Medicine, Peoria, Peoria, IL, USA
    Am J Kidney Dis 40:1342-7. 2002

Research Grants1

  1. Predicting Nephropathy in Type II Diabetes
    Patrick Walker; Fiscal Year: 2005
    ..These phase 1 proof of concept and feasibility studies will also lay the groundwork for more definitive studies related to predictive value as well as future preventive therapies with agents targeted toward a causative mechanism. ..