Michael Waisberg

Summary

Publications

  1. pmc The impact of genetic susceptibility to systemic lupus erythematosus on placental malaria in mice
    Michael Waisberg
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
    PLoS ONE 8:e62820. 2013
  2. pmc Microarray analysis of gene expression induced by sexual contact in Schistosoma mansoni
    Michael Waisberg
    Laboratorio de Genetica Bioquimica, Departmento de Imunologia e Bioquímica, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
    BMC Genomics 8:181. 2007
  3. doi request reprint Targeting glutamine metabolism rescues mice from late-stage cerebral malaria
    Emile B Gordon
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852
    Proc Natl Acad Sci U S A 112:13075-80. 2015
  4. pmc Testing in mice the hypothesis that melanin is protective in malaria infections
    Michael Waisberg
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
    PLoS ONE 7:e29493. 2012
  5. pmc Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis
    Michael Waisberg
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America Department of Pathology, University of Virginia, Charlottesville, Virginia, United States of America
    PLoS Pathog 10:e1004338. 2014
  6. pmc Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P
    Michael Waisberg
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA
    Proc Natl Acad Sci U S A 109:5429-34. 2012
  7. pmc Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice
    Michael Waisberg
    Laboratories of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA
    Proc Natl Acad Sci U S A 108:1122-7. 2011
  8. pmc Defibrotide interferes with several steps of the coagulation-inflammation cycle and exhibits therapeutic potential to treat severe malaria
    Ivo M B Francischetti
    Section of Vector Biology, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Arterioscler Thromb Vasc Biol 32:786-98. 2012
  9. doi request reprint Plasmodium falciparum Gametocyte-Specific Antibody Profiling Reveals Boosting through Natural Infection and Identifies Potential Markers of Gametocyte Exposure
    Jeff Skinner
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA
    Infect Immun 83:4229-36. 2015
  10. pmc Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria
    Ivo M B Francischetti
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
    PLoS ONE 9:e87140. 2014

Collaborators

Detail Information

Publications13

  1. pmc The impact of genetic susceptibility to systemic lupus erythematosus on placental malaria in mice
    Michael Waisberg
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
    PLoS ONE 8:e62820. 2013
    ..Thus, although SLE susceptibility was not protective in PM in mice it also did not have a negative impact on reproductive fitness...
  2. pmc Microarray analysis of gene expression induced by sexual contact in Schistosoma mansoni
    Michael Waisberg
    Laboratorio de Genetica Bioquimica, Departmento de Imunologia e Bioquímica, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
    BMC Genomics 8:181. 2007
    ..In order to study gene transcripts associated with sexual maturation and oviposition, we compared the gene expression profiles of sexually mature and immature parasites using DNA microarrays...
  3. doi request reprint Targeting glutamine metabolism rescues mice from late-stage cerebral malaria
    Emile B Gordon
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852
    Proc Natl Acad Sci U S A 112:13075-80. 2015
    ..These results suggest DON as a strong candidate for an effective adjunctive therapy for CM in African children...
  4. pmc Testing in mice the hypothesis that melanin is protective in malaria infections
    Michael Waisberg
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
    PLoS ONE 7:e29493. 2012
    ..Taken together, these results indicate that neither melanin nor vitamin D production improve survival in severe malaria...
  5. pmc Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis
    Michael Waisberg
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America Department of Pathology, University of Virginia, Charlottesville, Virginia, United States of America
    PLoS Pathog 10:e1004338. 2014
    ..Invasion of mosquito salivary glands (SGs) by Plasmodium falciparum sporozoites is an essential step in the malaria life cycle. How infection modulates gene expression, and affects hematophagy remains unclear...
  6. pmc Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P
    Michael Waisberg
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA
    Proc Natl Acad Sci U S A 109:5429-34. 2012
    ....
  7. pmc Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice
    Michael Waisberg
    Laboratories of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA
    Proc Natl Acad Sci U S A 108:1122-7. 2011
    ....
  8. pmc Defibrotide interferes with several steps of the coagulation-inflammation cycle and exhibits therapeutic potential to treat severe malaria
    Ivo M B Francischetti
    Section of Vector Biology, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Arterioscler Thromb Vasc Biol 32:786-98. 2012
    ..DF was investigated here as a drug to treat cerebral malaria...
  9. doi request reprint Plasmodium falciparum Gametocyte-Specific Antibody Profiling Reveals Boosting through Natural Infection and Identifies Potential Markers of Gametocyte Exposure
    Jeff Skinner
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA
    Infect Immun 83:4229-36. 2015
    ..These findings suggest that TBV-induced immunity would be boosted through natural gametocyte exposure, and that antibody responses to particular antigens may reliably indicate gametocyte exposure. ..
  10. pmc Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria
    Ivo M B Francischetti
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
    PLoS ONE 9:e87140. 2014
    ..The role of intracellular radical oxygen species (ROS) in pathogenesis of cerebral malaria (CM) remains incompletely understood...
  11. pmc Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments
    Akanksha Chaturvedi
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA
    Nat Immunol 12:1119-26. 2011
    ..Thus, the cellular location of the BCR serves to compartmentalize kinase activation to regulate the outcome of signaling...
  12. doi request reprint Inhibiting the Mammalian target of rapamycin blocks the development of experimental cerebral malaria
    Emile B Gordon
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA
    MBio 6:e00725. 2015
    ..These results open a new avenue for the development of highly selective adjunctive therapies for CM by targeting pathways that regulate host and parasite metabolism...
  13. ncbi request reprint Molecular and cellular mechanisms of cadmium carcinogenesis
    Michael Waisberg
    Department of Land Resource Science, University of Guelph, Guelph, Ont, Canada
    Toxicology 192:95-117. 2003
    ..It becomes clear that there exist multiple mechanisms which contribute to the carcinogenicity of cadmium, although the relative weights of these contributions are difficult to estimate...