F M E Wagenlehner

Summary

Publications

  1. pmc Concentrations in plasma, urinary excretion, and bactericidal activity of linezolid (600 milligrams) versus those of ciprofloxacin (500 milligrams) in healthy volunteers receiving a single oral dose
    Florian M E Wagenlehner
    Department of Urology, St Elisabeth Hospital, Straubing, Germany
    Antimicrob Agents Chemother 47:3789-94. 2003
  2. ncbi Chlamydial infections and prostatitis in men
    Florian M E Wagenlehner
    Urological Clinic, Hospital St Elisabeth, St Elisabeth Strasse 23, D 94315 Straubing, Germany
    BJU Int 97:687-90. 2006
  3. ncbi The Integral Theory System Questionnaire: an anatomically directed questionnaire to determine pelvic floor dysfunctions in women
    Florian Martin Erich Wagenlehner
    Clinic for Urology, Pediatric Urology and Andrology, Justus Liebig University, Giessen, Germany
    World J Urol 32:769-81. 2014
  4. ncbi [Biopsies of the kidney, prostate and urinary bladder]
    F M E Wagenlehner
    Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen und Marburg GmbH, Standort Gießen, Justus Liebig Universität Gießen, Rudolf Buchheim Straße 7, 35385, Giesen, Deutschland
    Urologe A 53:683-8. 2014
  5. doi [Infection and sepsis prevention in prostate biopsy]
    F M E Wagenlehner
    Klinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Giessen und Marburg GmbH, Standort Giessen, Justus Liebig Universitat, Rudolf Buchheim Str 7, 35392, Giessen, Deutschland
    Urologe A 52:1459-68; quiz 1467-8. 2013
  6. doi Antibiotic stewardship: a call for action by the urologic community
    Florian M E Wagenlehner
    Department of Urology, Paediatric Urology and Andrology of the Justus Liebig University, Giessen, Germany
    Eur Urol 64:358-60. 2013
  7. ncbi Bacterial prostatitis
    Florian M E Wagenlehner
    Clinic of Urology, Pediatric Urology and Andrology, Justus Liebig University, Rudolf Buchheim Str 7, 35385, Giessen, Germany
    World J Urol 31:711-6. 2013
  8. ncbi Prostatitis and andrological implications
    F Wagenlehner
    Department of Urology Pediatric Urology and Andrology Justus Liebig University of Giessen, D 35392 Giessen, Germany
    Minerva Urol Nefrol 65:117-23. 2013
  9. doi National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) symptom evaluation in multinational cohorts of patients with chronic prostatitis/chronic pelvic pain syndrome
    Florian M E Wagenlehner
    Department of Urology, Pediatric Urology and Andrology, Justus Liebig University, Giessen, Germany
    Eur Urol 63:953-9. 2013
  10. doi Infective complications after prostate biopsy: outcome of the Global Prevalence Study of Infections in Urology (GPIU) 2010 and 2011, a prospective multinational multicentre prostate biopsy study
    Florian M E Wagenlehner
    Department of Urology, Paediatric Urology and Andrology of the Justus Liebig University, Giessen, Germany
    Eur Urol 63:521-7. 2013

Detail Information

Publications82

  1. pmc Concentrations in plasma, urinary excretion, and bactericidal activity of linezolid (600 milligrams) versus those of ciprofloxacin (500 milligrams) in healthy volunteers receiving a single oral dose
    Florian M E Wagenlehner
    Department of Urology, St Elisabeth Hospital, Straubing, Germany
    Antimicrob Agents Chemother 47:3789-94. 2003
    ..Therefore, linezolid should be tested for use as empirical treatment for complicated urinary tract infections due to gram-positive uropathogens in an appropriate clinical trial...
  2. ncbi Chlamydial infections and prostatitis in men
    Florian M E Wagenlehner
    Urological Clinic, Hospital St Elisabeth, St Elisabeth Strasse 23, D 94315 Straubing, Germany
    BJU Int 97:687-90. 2006
  3. ncbi The Integral Theory System Questionnaire: an anatomically directed questionnaire to determine pelvic floor dysfunctions in women
    Florian Martin Erich Wagenlehner
    Clinic for Urology, Pediatric Urology and Andrology, Justus Liebig University, Giessen, Germany
    World J Urol 32:769-81. 2014
    ..It is based on the integral theory, which states that pelvic floor symptoms and prolapse are both caused by lax suspensory ligaments. The aim of the present study was to psychometrically validate the ITSQ...
  4. ncbi [Biopsies of the kidney, prostate and urinary bladder]
    F M E Wagenlehner
    Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen und Marburg GmbH, Standort Gießen, Justus Liebig Universität Gießen, Rudolf Buchheim Straße 7, 35385, Giesen, Deutschland
    Urologe A 53:683-8. 2014
    ..Biopsies of the kidney, prostate and urinary bladder are amongst the most frequent interventions in urology. A correct indication, preparation and performance are important to achieve good results and low complication rates...
  5. doi [Infection and sepsis prevention in prostate biopsy]
    F M E Wagenlehner
    Klinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Giessen und Marburg GmbH, Standort Giessen, Justus Liebig Universitat, Rudolf Buchheim Str 7, 35392, Giessen, Deutschland
    Urologe A 52:1459-68; quiz 1467-8. 2013
    ..This review aims to present the current evidence regarding infectious complications after prostate biopsy and strategies to reduce symptomatic infections and urosepsis. ..
  6. doi Antibiotic stewardship: a call for action by the urologic community
    Florian M E Wagenlehner
    Department of Urology, Paediatric Urology and Andrology of the Justus Liebig University, Giessen, Germany
    Eur Urol 64:358-60. 2013
    ....
  7. ncbi Bacterial prostatitis
    Florian M E Wagenlehner
    Clinic of Urology, Pediatric Urology and Andrology, Justus Liebig University, Rudolf Buchheim Str 7, 35385, Giessen, Germany
    World J Urol 31:711-6. 2013
    ..The prostatitis syndrome is classified into bacterial prostatitis (acute and chronic), chronic pelvic pain syndrome and asymptomatic prostatitis. The aim of this report is to review current management standards for bacterial prostatitis...
  8. ncbi Prostatitis and andrological implications
    F Wagenlehner
    Department of Urology Pediatric Urology and Andrology Justus Liebig University of Giessen, D 35392 Giessen, Germany
    Minerva Urol Nefrol 65:117-23. 2013
    ..Andrological implications of the prostatitis syndrome might encompass fertility issues, sexual dysfunctions and endocrinological alterations and influences...
  9. doi National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) symptom evaluation in multinational cohorts of patients with chronic prostatitis/chronic pelvic pain syndrome
    Florian M E Wagenlehner
    Department of Urology, Pediatric Urology and Andrology, Justus Liebig University, Giessen, Germany
    Eur Urol 63:953-9. 2013
    ....
  10. doi Infective complications after prostate biopsy: outcome of the Global Prevalence Study of Infections in Urology (GPIU) 2010 and 2011, a prospective multinational multicentre prostate biopsy study
    Florian M E Wagenlehner
    Department of Urology, Paediatric Urology and Andrology of the Justus Liebig University, Giessen, Germany
    Eur Urol 63:521-7. 2013
    ..Infection is a serious adverse effect of prostate biopsy (P-Bx), and recent reports suggest an increasing incidence...
  11. ncbi Anti-infective treatment of bacterial urinary tract infections
    F M E Wagenlehner
    Department of Urology and Pediatric Urology, Justus Liebig University, Giessen, Germany
    Curr Med Chem 15:1412-27. 2008
    ..The aim of this review is to describe the chemistry and structure-activity relationships of current antibiotics and promising substances in development for the treatment of UTI...
  12. ncbi Current anti-infective treatment of bacterial urinary tract infections
    Florian M E Wagenlehner
    Department of Urology, Justus Liebig University of Giessen, Rudolf Buchheim Str 7, D 35385 Giessen, Germany
    Mini Rev Med Chem 8:790-5. 2008
    ..In complicated UTI substances with activity against bacteria harbouring common resistance mechanisms are investigated. Additionally pharmacokinetic/ pharmacodynamic parameters are used to improve dosing strategies...
  13. doi Therapeutic challenges of urosepsis
    F M E Wagenlehner
    Justus Liebig University, Giessen, Germany
    Eur J Clin Invest 38:45-9. 2008
    ....
  14. ncbi [Rational antibiotic therapy of urinary tract infections]
    Florian M E Wagenlehner
    Klinik und Poliklinik für Urologie und Kinderurologie, Justus Liebig Universitat Giessen, Rudolf Buchheim Str 7, 35385 Giessen
    Med Monatsschr Pharm 31:385-90; quiz 391-2. 2008
    ..In complicated UTI the complicating factors have to be diagnosed and treated additionally to the antibiotic treatment. If not treated, a severe UTI and urosepsis can develop...
  15. pmc Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritis
    Florian M E Wagenlehner
    Clinic for Urology and Pediatric Urology, Justus Liebig University Giessen, Giessen, Germany
    Antimicrob Agents Chemother 53:1567-73. 2009
    ..Doripenem demonstrated excellent urinary bactericidal activity with the dose administered and appears to be a good alternative in the empirical treatment of cUTI...
  16. doi Chronic bacterial prostatitis (NIH type II): diagnosis, therapy and influence on the fertility status
    F M E Wagenlehner
    Clinic for Urology and Paediatric Urology, Justus Liebig University, Giessen, Germany
    Andrologia 40:100-4. 2008
    ..On the other hand, male accessory gland infection has been linked to male infertility. However, there is still a lack of evidence showing that bacterial prostatitis would have a negative impact on sperm quality...
  17. ncbi Antibiotics in urology: new essentials
    F M E Wagenlehner
    Clinic of Urology and Pediatric Urology, Justus Liebig University, Rudolf Buchheim Str 7, 35385, Giessen, Germany
    Urol Clin North Am 35:69-79; vi. 2008
    ..The use of antibiotics must keep up with continuous changes in antimicrobial resistance and be tailored to the needs of individual patients...
  18. ncbi Concentrations of moxifloxacin in plasma and urine, and penetration into prostatic fluid and ejaculate, following single oral administration of 400 mg to healthy volunteers
    F M E Wagenlehner
    Department of Urology, Justus Liebig University of Giessen, Germany
    Int J Antimicrob Agents 31:21-6. 2008
    ..Therefore, moxifloxacin might be a good alternative for the treatment of CBP, but further studies are warranted to establish this indication...
  19. ncbi Spectrum and antibiotic resistance of uropathogens from hospitalised patients with urinary tract infections: 1994-2005
    F M E Wagenlehner
    Department of Urology, Hospital St Elisabeth, Straubing, Germany
    Int J Antimicrob Agents 31:S25-34. 2008
    ..Therefore, ongoing surveillance of antibiotic resistance must be performed in every institution. Additionally, it reflects antibiotic and hospital infection policies in a defined department or institution...
  20. ncbi Management of a large healthcare-associated outbreak of Panton-Valentine leucocidin-positive meticillin-resistant Staphylococcus aureus in Germany
    F M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth, Straubing, Germany
    J Hosp Infect 67:114-20. 2007
    ..In this outbreak incomplete control of PVL(+) MRSA presumably resulted from difficult and delayed detection and decolonisation of carriers, incomplete compliance with control measures and lack of enforcement by public health authorities...
  21. ncbi Optimal management of urosepsis from the urological perspective
    Florian M E Wagenlehner
    Urologic Clinic, Justus Liebig University Giessen, Germany
    Int J Antimicrob Agents 30:390-7. 2007
    ..To achieve this goal an optimal interdisciplinary approach encompassing the emergency unit, urological specialties and intensive-care medicine is necessary...
  22. ncbi Therapy for prostatitis, with emphasis on bacterial prostatitis
    Florian M E Wagenlehner
    Justus Liebig University, Clinic for Urology and Pediatric Urology, Giessen, Giessen, Germany
    Expert Opin Pharmacother 8:1667-74. 2007
    ....
  23. ncbi The role of inflammation and infection in the pathogenesis of prostate carcinoma
    Florian M E Wagenlehner
    Department of Urology, Justus Liebig University Giessen, Germany
    BJU Int 100:733-7. 2007
    ..Summarising these epidemiological, genetic and cell biological aspects, infectious prostatitis might have a causative role in the complex and multifactorial process of prostate carcinogenesis...
  24. ncbi Pharmacokinetic characteristics of antimicrobials and optimal treatment of urosepsis
    Florian M E Wagenlehner
    Urologic Clinic, Justus Liebig University, Giessen, Germany
    Clin Pharmacokinet 46:291-305. 2007
    ..Since urosepsis quite often originates from catheter-associated UTI and urological interventions, optimal catheter care and optimal strategies to prevent nosocomial UTI may be able to reduce the frequency of urosepsis...
  25. doi An update on uncomplicated urinary tract infections in women
    Florian M E Wagenlehner
    Department of Urology and Pediatric Urology, Justus Liebig University, Giessen, Germany
    Curr Opin Urol 19:368-74. 2009
    ..Although severe complications are rare, their high prevalence causes remarkable costs in the healthcare systems...
  26. doi A pollen extract (Cernilton) in patients with inflammatory chronic prostatitis-chronic pelvic pain syndrome: a multicentre, randomised, prospective, double-blind, placebo-controlled phase 3 study
    Florian M E Wagenlehner
    Clinic for Urology, Paediatric Urology and Andrology, Justus Liebig University of Giessen, Giessen, Germany
    Eur Urol 56:544-51. 2009
    ..National Institutes of Health (NIH) category III prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent condition for which no standardised treatment exists...
  27. doi [Antibiotic prophylaxis in urology]
    F M E Wagenlehner
    Klinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen und Marburg, Standort Gießen, Rudolf Buchheim Strasse 7, Giesen, Germany
    Urologe A 50:1469-78; quiz 1479-80. 2011
    ..The antibiotic prophylaxis is part of the total antibiotic consumption and thus a factor contributing to emergence of antibiotic resistance. It is not a substitute for hygiene measures or operative precision...
  28. ncbi Emerging drugs for bacterial urinary tract infections
    Florian M E Wagenlehner
    Justus Liebig University, Clinic for Urology, Pediatric Urology and Andrology, Universitätsklinikum Giessen und Marburg, Standort Giessen, Giessen, Germany
    Expert Opin Emerg Drugs 15:375-97. 2010
    ..A dramatic, clinically significant increase in the antimicrobial resistance of uropathogens over the past 5 - 10 years calls for new concepts in the treatment of UTIs...
  29. doi [Primary and secondary prevention of urinary tract infections]
    F M E Wagenlehner
    Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Universitätskliniken Gießen und Marburg GmbH, Standort Gießen, Justus Liebig Universitat, Rudolf Buchheim Straße 7, 35392, Giesen, Deutschland
    Urologe A 50:1248, 1250-2, 1254-6. 2011
    ..The currently available catheter materials have only little influence on reducing catheter-associated rUTI...
  30. ncbi Epidemiology, treatment and prevention of healthcare-associated urinary tract infections
    F M E Wagenlehner
    Department of Urology, University Giessen, Giessen, Germany
    World J Urol 30:59-67. 2012
    ..However, cross-contamination and cross-infection may contribute to distribution of resistant uropathogens. The bacterial spectrum of HAUTI is broad, and antibiotic resistance is common...
  31. doi Pollen extract for chronic prostatitis-chronic pelvic pain syndrome
    Florian M E Wagenlehner
    Clinic for Urology, Pediatric Urology and Andrology, University Hospital Giessen and Marburg GmbH, Justus Liebig University, Rudolf Buchheim Strasse 7, D 35385 Giessen, Germany
    Urol Clin North Am 38:285-92. 2011
    ..Preclinical studies on pollen extract have shown effects on smooth muscles of the bladder and urethra, strong antiinflammatory effects, and antiproliferative effects...
  32. pmc Uncomplicated urinary tract infections
    Florian M E Wagenlehner
    Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Justus Liebig Universitat, Giessen, Giessen, Germany
    Dtsch Arztebl Int 108:415-23. 2011
    ..The new S3 guideline contains updated recommendations...
  33. doi [Practice management of chronic bacterial prostatitis with levofloxacin]
    F Wagenlehner
    Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Justus Liebig Universitat, Giessen
    Aktuelle Urol 42:184-9. 2011
    ..2 %, n = 3 / 243), The results of this study confirm the efficacy and safety of levofloxacin in the treatment of chronic bacterial prostatitis in daily clinical practice...
  34. doi Urinary pharmacokinetics and bactericidal activity of finafloxacin (200 and 800 mg) in healthy volunteers receiving a single oral dose
    Florian M E Wagenlehner
    Department of Urology, Pediatric Urology and Andrology, Justus Liebig University Giessen, Giessen, Germany
    Chemotherapy 57:97-107. 2011
    ..Finafloxacin is a novel 8-cyano-fluoroquinolone under investigation for treatment of urinary tract infection...
  35. doi [National S3 guideline on uncomplicated urinary tract infection: recommendations for treatment and management of uncomplicated community-acquired bacterial urinary tract infections in adult patients]
    F M E Wagenlehner
    Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Universitätsklinikum Giessen und Marburg GmbH, Justus Liebig Universitat Giessen, Rudolf Buchheim Straße 7, 35385 Giessen, Deutschland
    Urologe A 50:153-69. 2011
    ..Increasing antibiotic resistance rates and a new appreciation of the epidemiological side effects of antibiotics ("collateral damage") have warranted an update of the guidelines on uncomplicated UTI as an S3 clinical guideline...
  36. doi [Uncomplicated urinary tract infection and treatment]
    F M E Wagenlehner
    Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Justus Liebig Universitat, Giessen
    Aktuelle Urol 42:33-7. 2011
    ..Due to the increasing antibiotic resistance and the emergence of multiresistant uropathogens, empirical antibiotic treatment becomes more difficult. Therefore the results of susceptibility testing should be awaited whenever possible...
  37. doi Urodynamic impact of acute urinary retention in patients with benign prostatic hyperplasia: a 2-year follow-up after transurethral resection of the prostate
    Florian M E Wagenlehner
    Clinic for Urology, Pediatric Urology and Andrology, Justus Liebig University of Giessen, Giessen, Germany
    Urol Int 86:73-9. 2011
    ....
  38. doi Surgical reconstruction of pelvic floor descent: anatomic and functional aspects
    F M E Wagenlehner
    Clinic of Urology, Pediatric Urology and Andrology, Justus Liebig University Rudolf Buchheim Strasse 7 DE 35385 Giessen, Germany
    Urol Int 84:1-9. 2010
    ..The human pelvic floor is a complex structure and pelvic floor dysfunction is seen frequently in females...
  39. doi [Functional aspects of pelvic floor surgery]
    F M E Wagenlehner
    Klinik für Urologie, Kinderurologie und Andrologie, Justus Liebig Universitat Giessen, Giessen
    Aktuelle Urol 40:345-50. 2009
    ..An exact identification of the anatomic lesions preoperatively is eminently necessary, to allow for an exact anatomic reconstruction with respect to the muscular forces of the pelvic floor...
  40. pmc Prostatitis and male pelvic pain syndrome: diagnosis and treatment
    Florian M E Wagenlehner
    Klinik und Poliklinik für Urologie und Kinderurologie, Justus Liebig UniversitätGiessen, Giessen, Germany
    Dtsch Arztebl Int 106:175-83. 2009
    ....
  41. ncbi [Prostatitis syndrome]
    Florian M E Wagenlehner
    Klinik und Poliklinik für Urologie und Kinderurologie, Justus Liebig Universitat Giessen
    Urologe A 46:W185-96; quiz W197. 2007
    ..Accompanying symptomatic therapy is also recommended. It is important, however, to keep the patient fully informed about the diagnostic and therapeutic limitations...
  42. ncbi Serum and prostatic tissue concentrations of moxifloxacin in patients undergoing transurethral resection of the prostate
    F M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth, Straubing, Germany
    J Chemother 18:485-9. 2006
    ....
  43. ncbi Emerging drugs for bacterial urinary tract infections
    Florian M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth, St Elisabeth Street 23, D 94315 Straubing, Germany
    Expert Opin Emerg Drugs 10:275-98. 2005
    ..The aim of this review is to highlight the existing, and to describe emerging, treatment options for UTIs...
  44. ncbi Emergence of antibiotic resistance amongst hospital-acquired urinary tract infections and pharmacokinetic/pharmacodynamic considerations
    F M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth Straubing, St Elisabeth Str 23, D 94315 Straubing, Germany
    J Hosp Infect 60:191-200. 2005
    ..The emergence of resistance can possibly be lowered by adequate drug selection and dosing. Increasing antibiotic resistance requires more prudent use of antimicrobial drugs...
  45. ncbi [Bacterial urinary tract infections--what is only an annoyance, when is risk involved?]
    F M E Wagenlehner
    Urologische Klinik, Klinikum St Elisabeth, Straubing
    Ther Umsch 59:464-8. 2002
    ..Therapy in uncomplicated UTI is essentially antibacterial, whereas in complicated UTI additional treatment of complicating factors is mandatory...
  46. ncbi Prospective, randomized, multicentric, open, comparative study on the efficacy of a prophylactic single dose of 500 mg levofloxacin versus 1920 mg trimethoprim/sulfamethoxazole versus a control group in patients undergoing TUR of the prostate
    F M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth, St Elisabeth Str 23, D 94315 Straubing, Germany
    Eur Urol 47:549-56. 2005
    ..The aims were to assess the rate of bacteriuria (cfu> or =10(4)/ml) 5 to 7 days, and 3 to 5 weeks after TUR-P, as well as postoperative complications...
  47. ncbi [Therapy of bladder weakness]
    F M Wagenlehner
    Klinikum St Elisabeth, Straubing, Germany
    Dtsch Med Wochenschr 130:118. 2005
  48. ncbi Molecular epidemiology and antibiotic resistance of Enterobacter spp. from three distinct populations in Grampian, UK
    F M E Wagenlehner
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
    Int J Antimicrob Agents 20:419-25. 2002
    ..Isolates (27%) were clonally related and typed in four clusters. Consecutive isolates were studied in selected patients showing minor genomic changes. One environmental isolate from a deep sink at ITU was related to a patient's isolate...
  49. ncbi Antibiotic treatment for urinary tract infections: pharmacokinetic/pharmacodynamic principles
    Florian M E Wagenlehner
    Hospital St Elisabeth Straubing, Urologic Clinic, St Elisabeth Str 23, D 94315 Straubing, Germany
    Expert Rev Anti Infect Ther 2:923-31. 2004
    ..In uncomplicated UTIs, antimicrobial therapy is usually empiric, whereas in complicated UTIs antibiotic therapy should be more individualized; tailored to the individual patient...
  50. ncbi Antimicrobial treatment of prostatitis
    F Me Wagenlehner
    Urologic Clinic, Hospital St Elisabeth Straubing, St Elisabeth Str 23, D 94315 Straubing, Germany
    Expert Rev Anti Infect Ther 1:275-82. 2003
    ....
  51. ncbi [Spectrum of pathogens and resistance to antibiotics in urinary tract infections and the consequences for antibiotic treatment: study of urology inpatients with urinary tract infections (1994-2001)]
    E Wagenlehner
    Urologische Klinik, Klinikum St Elisabeth, Straubing
    Urologe A 42:13-25. 2003
    ..To draw the correct conclusions from these data, the urologist must either be personally involved in the analytical procedure or receive the interim results promptly...
  52. ncbi [How should chronic recurrent cystitis be treated?]
    F M E Wagenlehner
    Urologische Klinik, Klinikum St Elisabeth, Straubing
    Dtsch Med Wochenschr 128:158. 2003
  53. ncbi Prostatitis: the role of antibiotic treatment
    F M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth, St Elisabeth Strasse 23, 94315 Straubing, Germany
    World J Urol 21:105-8. 2003
    ..There is no consensus regarding the role of antibiotic treatment in patients with non-inflammatory CPPS (NIH category IIIB) and asymptomatic prostatitis (NIH category IV)...
  54. ncbi Clinically significant borderline resistance of sequential clinical isolates of Klebsiella pneumoniae
    F M E Wagenlehner
    Institute for Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany
    Int J Antimicrob Agents 22:367-73. 2003
    ..Further increase of MIC to fluoroquinolones in vivo and in vitro was distinct. Kpn#1-SEL, selected in vitro, acquired a GyrA target mutation, whereas in Kpn#2 no known resistance mechanism could be detected...
  55. ncbi The role of antibiotics in chronic bacterial prostatitis
    F M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth Straubing, St Elisabeth Str 23, D 94315 Straubing, Germany
    Int J Antimicrob Agents 26:1-7. 2005
    ..Nevertheless, the concentrations at the site of infection of most of the fluoroquinolones should be sufficient for the treatment of CBP and vesiculitis caused by susceptible pathogens...
  56. ncbi Asymptomatic bacteriuria in elderly patients: significance and implications for treatment
    Florian M E Wagenlehner
    Department of Urology, University of Giessen, Giessen, Germany
    Drugs Aging 22:801-7. 2005
    ..Therefore, until the implications of the bacteria involved in ASB are fully understood, implementing the same hygienic precautions as are used in individuals with symptomatic UTIs should at least be undertaken...
  57. ncbi Pharmacokinetics of ciprofloxacin XR (1000 mg) versus levofloxacin (500 mg) in plasma and urine of male and female healthy volunteers receiving a single oral dose
    Florian M E Wagenlehner
    Department of Urology, St Elisabeth Hospital, Straubing, Germany
    Int J Antimicrob Agents 27:7-14. 2006
    ..Therefore, it can be assumed that the two doses investigated can be considered equivalent for the treatment of UTI...
  58. ncbi Hospital-acquired urinary tract infections
    F M Wagenlehner
    Urologic Clinic, Hospital St Elisabeth, Teaching Hospital of the Technical University Munich, St Elisabeth Str 23, D 94315, Straubing, Germany
    J Hosp Infect 46:171-81. 2000
    ..Additionally the complicating factors must be diagnosed and treated adequately. The best prophylaxis is to minimize the duration of the urinary catheter and to employ general hygienic procedures...
  59. ncbi Concentrations in plasma, urinary excretion and bactericidal activity of levofloxacin (500 mg) versus ciprofloxacin (500 mg) in healthy volunteers receiving a single oral dose
    Florian M E Wagenlehner
    Department of Urology, St Elisabeth Hospital, St Elisabeth Str 23, D 94315 Straubing, Germany
    Int J Antimicrob Agents 28:551-9. 2006
    ....
  60. pmc Urinary bactericidal activity of extended-release ciprofloxacin (1,000 milligrams) versus levofloxacin (500 milligrams) in healthy volunteers receiving a single oral dose
    Florian M E Wagenlehner
    Department of Urology, Hospital St Elisabeth, St Elisabeth Str 23, D 94315 Straubing, Germany
    Antimicrob Agents Chemother 50:3947-9. 2006
    ..Areas under UBT-time curves were significantly larger for Proteus mirabilis with XR ciprofloxacin and for staphylococci with levofloxacin...
  61. ncbi Incidence of nosocomial urinary tract infections on a surgical intensive care unit and implications for management
    F M E Wagenlehner
    Urologic Clinic, St Elisabeth Hospital, Straubing, Germany
    Int J Antimicrob Agents 28:S86-90. 2006
    ..2 (symptomatic UTI) and 14.0 (asymptomatic UTI). Although asymptomatic NUTI usually deserves no therapy, it needs to be considered carefully in terms of its environmental impact on the emergence of bacterial resistance...
  62. ncbi Emergence of antibiotic resistance and prudent use of antibiotic therapy in nosocomially acquired urinary tract infections
    F M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth, St Elisabeth Strasse 23, D 94315 Straubing, Germany
    Int J Antimicrob Agents 23:S24-9. 2004
    ..Only those substances with high antibacterial activity, good bioavailability and those that are mainly excreted by the kidneys should be chosen and they have to be administered at sufficiently high doses...
  63. ncbi [Therapy of the acute uncomplicated urinary tract infection]
    F Wagenlehner
    Urologische Klinik, Klinikum St Elisabeth, St Elisabeth Strasse 23, 94315 Straubing
    Urologe A 45:429-32, 434-5. 2006
    ..The Infectious Diseases Society of America (IDSA) developed evidence-based guidelines for the treatment of acute uncomplicated cystitis and acute uncomplicated pyelonephritis, which were recently updated by other expert groups...
  64. ncbi [Guidelines for management of urinary tract infections in adults--an initiative]
    F Wagenlehner
    Urologische Klinik, Klinikum St Elisabeth, St Elisabeth Strasse 23, 94315, Straubing
    Urologe A 45:464-6. 2006
  65. ncbi Uraemia, psychosis, young patient: an uncommon link. Urinary tract and miliary tuberculosis
    Florian M E Wagenlehner
    Urology Clinic, St Elisabeth Hospital, D 94315 Straubing, Germany
    Nephrol Dial Transplant 21:1113-6. 2006
  66. ncbi [Therapy of prostatitis syndrome]
    F M Wagenlehner
    Urologische Klinik, Klinikum St Elisabeth, Akademisches Lehrkrankenhaus, Technische Universitat Munchen, St Elisabeth Strasse 23, 94315 Straubing
    Urologe A 40:24-8. 2001
    ..It is important, however, to keep the patient fully informed about the diagnostic and therapeutic problems not to interfere with a trustful therapist-patient relationship...
  67. ncbi Chlamydial infections in urology
    Florian M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth, Straubing, Str 23, 94315 Straubing, Germany
    World J Urol 24:4-12. 2006
    ..For treatment, only some antibiotics are effective because of the intracellular habitat of the pathogen. Prevention of infection comprises treatment and screening efforts...
  68. ncbi Treatment of bacterial urinary tract infections: presence and future
    Florian M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth, Straubing, Germany
    Eur Urol 49:235-44. 2006
    ..Decrease the amount of antibiotics administered, optimal dosing, prevention of infection and development of new antibiotic substances. The aim of this review is to highlight the current and to describe future treatment options for UTIs...
  69. ncbi Abdominal actinomycosis
    F M E Wagenlehner
    First Department of Surgery, St Elisabeth, Straubing, Germany
    Clin Microbiol Infect 9:881-5. 2003
    ..Even when infection had spread extensively, combined operative and antibiotic therapy cured most of the cases...
  70. doi Antimicrobials in urogenital infections
    Florian M E Wagenlehner
    Department of Urology, Pediatric Urology and Andrology, Justus Liebig University, Giessen, Germany
    Int J Antimicrob Agents 38:3-10. 2011
    ..Furthermore in genital infections fastidious organisms, such as Chlamydia or Mycoplasma spp. have to be considered with respect to their antimicrobial susceptibility...
  71. doi Urosepsis--from the view of the urologist
    Florian M E Wagenlehner
    Urologic Clinic, Justus Liebig University Giessen, Germany
    Int J Antimicrob Agents 38:51-7. 2011
    ..Dosage of an antibiotic in the septic patient generally has to be high to ensure adequate pharmacological exposure in the individual patient...
  72. ncbi Current challenges in the treatment of complicated urinary tract infections and prostatitis
    F M E Wagenlehner
    Department of Urology, Hospital St Elisabeth, Straubing, Germany
    Clin Microbiol Infect 12:67-80. 2006
    ....
  73. ncbi [Recurrent urinary tract infections should not be treated cavalierly. First verify the diagnosis!]
    F M E Wagenlehner
    Urologische Klinik, Klinikum St Elisabeth, Straubing
    MMW Fortschr Med 145:37-9. 2003
    ..For the prevention of recurrent UTI, antibiotics, functional foods, injections, probiotic agents and other measures are recommended with varying potential for success...
  74. doi Acute bacterial prostatitis and chronic prostatitis/chronic pelvic pain syndrome: andrological implications
    W Weidner
    Department of Urology and Paediatric Urology, University of Giessen, Giessen, Germany
    Andrologia 40:105-12. 2008
    ..CP/CPPS therapy has the goal to reduce pelvic pain. However, treatment regimens are not as standardised. Andrological side-effects are well defined and mainly due to the functional background of these agents...
  75. ncbi Fluoroquinolone antimicrobial agents in the treatment of prostatitis and recurrent urinary tract infections in men
    F M E Wagenlehner
    Urologic Clinic, Hospital St Elisabeth Straubing, St Elisabeth Str 23, D 94315 Straubing, Germany
    Curr Urol Rep 5:309-16. 2004
    ....
  76. ncbi Spectrum and antibiotic resistance of uropathogens from hospitalized patients with urinary tract infections: 1994-2000
    F M E Wagenlehner
    Department of Urology, Hospital St Elisabeth, Straubing, Germany
    Int J Antimicrob Agents 19:557-64. 2002
    ..Ciprofloxacin was the best oral antibiotic for the empirical treatment of urinary tract infection (UTI) due to Gram-negative rods and ampicillin/sulbactam for the treatment of UTI with Gram-positive cocci...
  77. ncbi New drugs for Gram-positive uropathogens
    F M E Wagenlehner
    Department of Urology, Hospital St Elisabeth, St Elisabeth Strasse 23, D 94315 Straubing, Germany
    Int J Antimicrob Agents 24:S39-43. 2004
    ..The pharmacokinetics and the mode of action of these two antibiotics are discussed together with some clinical data in the context of therapeutic use in patients with complicated UTIs...
  78. doi [Urosepsis and treatment]
    F M E Wagenlehner
    Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Universitätsklinikum Giessen und Marburg GmbH Standort Giessen, Justus Liebig Universitat, Rudolf Buchheim Strasse 7, 35385, Giessen, Deutschland
    Urologe A 49:618-22. 2010
    ..The intensive care of the septic patient needs to be started as early as on patient admission and, where necessary, continued on the intensive care ward...
  79. ncbi Epidemiological analysis of the spread of pathogens from a urological ward using genotypic, phenotypic and clinical parameters
    F M E Wagenlehner
    Urologic Clinic, St Elisabeth Hospital, St Elisabeth Strasse 23, D 94315 Straubing, Germany
    Int J Antimicrob Agents 19:583-91. 2002
    ..Altogether, there was a high rate of clonal relationship amongst uropathogens in our urological ward and we conclude that hygienic means and measures are far from being optimal...
  80. ncbi [Urogenital infections in the elderly]
    W Weidner
    Klinik und Poliklinik für Urologie und Kinderurologie, Justus Liebig Universitat Giessen, Rudolf Buchheim Strasse 7, 35385 Giessen
    Urologe A 41:328-32. 2002
    ..Urologic implications resulting from this set of difficulties have not yet been investigated sufficiently and need further evidence-based work-up...
  81. ncbi In vitro activity of daptomycin versus linezolid and vancomycin against gram-positive uropathogens and ampicillin against enterococci, causing complicated urinary tract infections
    Florian M E Wagenlehner
    Department of Urology, St Elisabeth Hospital, Straubing, Germany
    Chemotherapy 51:64-9. 2005
    ..The existing therapeutic options for complicated urinary tract infections (UTI) caused by gram-positive uropathogens are not always optimal. Therefore, newer antimicrobials have to be assessed...
  82. ncbi [Chlamydia infections of the male: what is relevant for urologists?]
    W Weidner
    Klinik und Poliklinik für Urologie und Kinderurologie, Justus Liebig Universitat, Rudolf Buchheim Strasse 7, 35292 Giessen, Deutschland
    Urologe A 45:1504-8. 2006
    ..This review summarizes the most current developments in the diagnostics and therapeutical approaches in Chlamydia infections of the male accessory sex glands...