Concentrations in plasma, urinary excretion, and bactericidal activity of linezolid (600 milligrams) versus those of ciprofloxacin (500 milligrams) in healthy volunteers receiving a single oral doseFlorian M E Wagenlehner
Department of Urology, St. Elisabeth Hospital, Straubing, Germany
Antimicrob Agents Chemother 47:3789-94. 2003
..Therefore, linezolid should be tested for use as empirical treatment for complicated urinary tract infections due to gram-positive uropathogens in an appropriate clinical trial...
Chlamydial infections and prostatitis in menFlorian M E Wagenlehner
Urological Clinic, Hospital St. Elisabeth, St. Elisabeth Strasse 23, D-94315 Straubing, Germany
BJU Int 97:687-90. 2006
Infective Complications After Prostate Biopsy: Outcome of the Global Prevalence Study of Infections in Urology (GPIU) 2010 and 2011, A Prospective Multinational Multicentre Prostate Biopsy StudyFlorian M E Wagenlehner
Department of Urology, Paediatric Urology and Andrology of the Justus Liebig University, Giessen, Germany Electronic address
Eur Urol 63:521-7. 2013
..Infection is a serious adverse effect of prostate biopsy (P-Bx), and recent reports suggest an increasing incidence...
A pollen extract (Cernilton) in patients with inflammatory chronic prostatitis-chronic pelvic pain syndrome: a multicentre, randomised, prospective, double-blind, placebo-controlled phase 3 studyFlorian M E Wagenlehner
Clinic for Urology, Paediatric Urology and Andrology, Justus Liebig University of Giessen, Giessen, Germany
Eur Urol 56:544-51. 2009
..National Institutes of Health (NIH) category III prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent condition for which no standardised treatment exists...
Therapeutic challenges of urosepsisF M E Wagenlehner
Justus Liebig University, Giessen, Germany
Eur J Clin Invest 38:45-9. 2008
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Current anti-infective treatment of bacterial urinary tract infectionsFlorian M E Wagenlehner
Department of Urology, Justus Liebig University of Giessen, Rudolf Buchheim Str 7, D 35385 Giessen, Germany
Mini Rev Med Chem 8:790-5. 2008
..In complicated UTI substances with activity against bacteria harbouring common resistance mechanisms are investigated. Additionally pharmacokinetic/ pharmacodynamic parameters are used to improve dosing strategies...
Anti-infective treatment of bacterial urinary tract infectionsF M E Wagenlehner
Department of Urology and Pediatric Urology, Justus Liebig University, Giessen, Germany
Curr Med Chem 15:1412-27. 2008
..The aim of this review is to describe the chemistry and structure-activity relationships of current antibiotics and promising substances in development for the treatment of UTI...
Chronic bacterial prostatitis (NIH type II): diagnosis, therapy and influence on the fertility statusF M E Wagenlehner
Clinic for Urology and Paediatric Urology, Justus Liebig University, Giessen, Germany
Andrologia 40:100-4. 2008
..On the other hand, male accessory gland infection has been linked to male infertility. However, there is still a lack of evidence showing that bacterial prostatitis would have a negative impact on sperm quality...
Antibiotics in urology: new essentialsF M E Wagenlehner
Clinic of Urology and Pediatric Urology, Justus Liebig University, Rudolf Buchheim Str 7, 35385, Giessen, Germany
Urol Clin North Am 35:69-79; vi. 2008
..The use of antibiotics must keep up with continuous changes in antimicrobial resistance and be tailored to the needs of individual patients...
Spectrum and antibiotic resistance of uropathogens from hospitalised patients with urinary tract infections: 1994-2005F M E Wagenlehner
Department of Urology, Hospital St Elisabeth, Straubing, Germany
Int J Antimicrob Agents 31:S25-34. 2008
..Therefore, ongoing surveillance of antibiotic resistance must be performed in every institution. Additionally, it reflects antibiotic and hospital infection policies in a defined department or institution...
Management of a large healthcare-associated outbreak of Panton-Valentine leucocidin-positive meticillin-resistant Staphylococcus aureus in GermanyF M E Wagenlehner
Urologic Clinic, Hospital St Elisabeth, Straubing, Germany
J Hosp Infect 67:114-20. 2007
..In this outbreak incomplete control of PVL(+) MRSA presumably resulted from difficult and delayed detection and decolonisation of carriers, incomplete compliance with control measures and lack of enforcement by public health authorities...
Optimal management of urosepsis from the urological perspectiveFlorian M E Wagenlehner
Urologic Clinic, Justus Liebig University Giessen, Germany
Int J Antimicrob Agents 30:390-7. 2007
..To achieve this goal an optimal interdisciplinary approach encompassing the emergency unit, urological specialties and intensive-care medicine is necessary...
Therapy for prostatitis, with emphasis on bacterial prostatitisFlorian M E Wagenlehner
Justus Liebig University, Clinic for Urology and Pediatric Urology, Giessen, Giessen, Germany
Expert Opin Pharmacother 8:1667-74. 2007
....
The role of inflammation and infection in the pathogenesis of prostate carcinomaFlorian M E Wagenlehner
Department of Urology, Justus Liebig University Giessen, Germany
BJU Int 100:733-7. 2007
..Summarising these epidemiological, genetic and cell biological aspects, infectious prostatitis might have a causative role in the complex and multifactorial process of prostate carcinogenesis...
Pharmacokinetic characteristics of antimicrobials and optimal treatment of urosepsisFlorian M E Wagenlehner
Urologic Clinic, Justus Liebig University, Giessen, Germany
Clin Pharmacokinet 46:291-305. 2007
..Since urosepsis quite often originates from catheter-associated UTI and urological interventions, optimal catheter care and optimal strategies to prevent nosocomial UTI may be able to reduce the frequency of urosepsis...
[Prostatitis syndrome]Florian M E Wagenlehner
Klinik und Poliklinik für Urologie und Kinderurologie, Justus Liebig Universitat Giessen
Urologe A 46:W185-96; quiz W197. 2007
..Accompanying symptomatic therapy is also recommended. It is important, however, to keep the patient fully informed about the diagnostic and therapeutic limitations...
Serum and prostatic tissue concentrations of moxifloxacin in patients undergoing transurethral resection of the prostateF M E Wagenlehner
Urologic Clinic, Hospital St Elisabeth, Straubing, Germany
J Chemother 18:485-9. 2006
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Concentrations of moxifloxacin in plasma and urine, and penetration into prostatic fluid and ejaculate, following single oral administration of 400 mg to healthy volunteersF M E Wagenlehner
Department of Urology, Justus Liebig University of Giessen, Germany
Int J Antimicrob Agents 31:21-6. 2008
..Therefore, moxifloxacin might be a good alternative for the treatment of CBP, but further studies are warranted to establish this indication...
Concentrations in plasma, urinary excretion and bactericidal activity of levofloxacin (500 mg) versus ciprofloxacin (500 mg) in healthy volunteers receiving a single oral doseFlorian M E Wagenlehner
Department of Urology, St Elisabeth Hospital, St Elisabeth Str 23, D 94315 Straubing, Germany
Int J Antimicrob Agents 28:551-9. 2006
....
[Rational antibiotic therapy of urinary tract infections]Florian M E Wagenlehner
Klinik und Poliklinik für Urologie und Kinderurologie, Justus Liebig Universitat Giessen, Rudolf Buchheim Str 7, 35385 Giessen
Med Monatsschr Pharm 31:385-90; quiz 391-2. 2008
..In complicated UTI the complicating factors have to be diagnosed and treated additionally to the antibiotic treatment. If not treated, a severe UTI and urosepsis can develop...
Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritisFlorian M E Wagenlehner
Clinic for Urology and Pediatric Urology, Justus Liebig University Giessen, Giessen, Germany
Antimicrob Agents Chemother 53:1567-73. 2009
..Doripenem demonstrated excellent urinary bactericidal activity with the dose administered and appears to be a good alternative in the empirical treatment of cUTI...
[Antibiotic prophylaxis in urology]F M E Wagenlehner
Klinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen und Marburg, Standort Gießen, Rudolf Buchheim Strasse 7, Giesen, Germany
Urologe A 50:1469-78; quiz 1479-80. 2011
..The antibiotic prophylaxis is part of the total antibiotic consumption and thus a factor contributing to emergence of antibiotic resistance. It is not a substitute for hygiene measures or operative precision...
[Primary and secondary prevention of urinary tract infections]F M E Wagenlehner
Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Universitätskliniken Gießen und Marburg GmbH, Standort Gießen, Justus Liebig Universitat, Rudolf Buchheim Straße 7, 35392, Giesen, Deutschland
Urologe A 50:1248, 1250-2, 1254-6. 2011
..The currently available catheter materials have only little influence on reducing catheter-associated rUTI...
Epidemiology, treatment and prevention of healthcare-associated urinary tract infectionsF M E Wagenlehner
Department of Urology, University Giessen, Giessen, Germany
World J Urol 30:59-67. 2012
..However, cross-contamination and cross-infection may contribute to distribution of resistant uropathogens. The bacterial spectrum of HAUTI is broad, and antibiotic resistance is common...
Pollen extract for chronic prostatitis-chronic pelvic pain syndromeFlorian M E Wagenlehner
Clinic for Urology, Pediatric Urology and Andrology, University Hospital Giessen and Marburg GmbH, Justus Liebig University, Rudolf Buchheim Strasse 7, D 35385 Giessen, Germany
Urol Clin North Am 38:285-92. 2011
..Preclinical studies on pollen extract have shown effects on smooth muscles of the bladder and urethra, strong antiinflammatory effects, and antiproliferative effects...
Uncomplicated urinary tract infectionsFlorian M E Wagenlehner
Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Justus Liebig Universitat, Giessen, Giessen, Germany
Dtsch Arztebl Int 108:415-23. 2011
..The new S3 guideline contains updated recommendations...
[Practice management of chronic bacterial prostatitis with levofloxacin]F Wagenlehner
Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Justus Liebig Universitat, Giessen
Aktuelle Urol 42:184-9. 2011
..2 %, n = 3 / 243), The results of this study confirm the efficacy and safety of levofloxacin in the treatment of chronic bacterial prostatitis in daily clinical practice...
Urinary pharmacokinetics and bactericidal activity of finafloxacin (200 and 800 mg) in healthy volunteers receiving a single oral doseFlorian M E Wagenlehner
Department of Urology, Pediatric Urology and Andrology, Justus Liebig University Giessen, Giessen, Germany
Chemotherapy 57:97-107. 2011
..Finafloxacin is a novel 8-cyano-fluoroquinolone under investigation for treatment of urinary tract infection...
[National S3 guideline on uncomplicated urinary tract infection: recommendations for treatment and management of uncomplicated community-acquired bacterial urinary tract infections in adult patients]F M E Wagenlehner
Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Universitätsklinikum Giessen und Marburg GmbH, Justus Liebig Universitat Giessen, Rudolf Buchheim Straße 7, 35385 Giessen, Deutschland
Urologe A 50:153-69. 2011
..Increasing antibiotic resistance rates and a new appreciation of the epidemiological side effects of antibiotics ("collateral damage") have warranted an update of the guidelines on uncomplicated UTI as an S3 clinical guideline...
[Uncomplicated urinary tract infection and treatment]F M E Wagenlehner
Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Justus Liebig Universitat, Giessen
Aktuelle Urol 42:33-7. 2011
..Due to the increasing antibiotic resistance and the emergence of multiresistant uropathogens, empirical antibiotic treatment becomes more difficult. Therefore the results of susceptibility testing should be awaited whenever possible...
Urodynamic impact of acute urinary retention in patients with benign prostatic hyperplasia: a 2-year follow-up after transurethral resection of the prostateFlorian M E Wagenlehner
Clinic for Urology, Pediatric Urology and Andrology, Justus Liebig University of Giessen, Giessen, Germany
Urol Int 86:73-9. 2011
....
Emerging drugs for bacterial urinary tract infectionsFlorian M E Wagenlehner
Justus Liebig University, Clinic for Urology, Pediatric Urology and Andrology, Universitätsklinikum Giessen und Marburg, Standort Giessen, Giessen, Germany
Expert Opin Emerg Drugs 15:375-97. 2010
..A dramatic, clinically significant increase in the antimicrobial resistance of uropathogens over the past 5 - 10 years calls for new concepts in the treatment of UTIs...
Surgical reconstruction of pelvic floor descent: anatomic and functional aspectsF M E Wagenlehner
Clinic of Urology, Pediatric Urology and Andrology, Justus Liebig University Rudolf Buchheim Strasse 7 DE 35385 Giessen, Germany
Urol Int 84:1-9. 2010
..The human pelvic floor is a complex structure and pelvic floor dysfunction is seen frequently in females...
[Functional aspects of pelvic floor surgery]F M E Wagenlehner
Klinik für Urologie, Kinderurologie und Andrologie, Justus Liebig Universitat Giessen, Giessen
Aktuelle Urol 40:345-50. 2009
..An exact identification of the anatomic lesions preoperatively is eminently necessary, to allow for an exact anatomic reconstruction with respect to the muscular forces of the pelvic floor...
Prostatitis and male pelvic pain syndrome: diagnosis and treatmentFlorian M E Wagenlehner
Klinik und Poliklinik für Urologie und Kinderurologie, Justus Liebig UniversitätGiessen, Giessen, Germany
Dtsch Arztebl Int 106:175-83. 2009
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An update on uncomplicated urinary tract infections in womenFlorian M E Wagenlehner
Department of Urology and Pediatric Urology, Justus Liebig University, Giessen, Germany
Curr Opin Urol 19:368-74. 2009
..Although severe complications are rare, their high prevalence causes remarkable costs in the healthcare systems...
Urinary bactericidal activity of extended-release ciprofloxacin (1,000 milligrams) versus levofloxacin (500 milligrams) in healthy volunteers receiving a single oral doseFlorian M E Wagenlehner
Department of Urology, Hospital St Elisabeth, St Elisabeth Str 23, D 94315 Straubing, Germany
Antimicrob Agents Chemother 50:3947-9. 2006
..Areas under UBT-time curves were significantly larger for Proteus mirabilis with XR ciprofloxacin and for staphylococci with levofloxacin...
Incidence of nosocomial urinary tract infections on a surgical intensive care unit and implications for managementF M E Wagenlehner
Urologic Clinic, St Elisabeth Hospital, Straubing, Germany
Int J Antimicrob Agents 28:S86-90. 2006
..2 (symptomatic UTI) and 14.0 (asymptomatic UTI). Although asymptomatic NUTI usually deserves no therapy, it needs to be considered carefully in terms of its environmental impact on the emergence of bacterial resistance...
[Therapy of bladder weakness]F M Wagenlehner
Klinikum St. Elisabeth, Straubing, Germany
Dtsch Med Wochenschr 130:118. 2005
Antibiotic treatment for urinary tract infections: pharmacokinetic/pharmacodynamic principlesFlorian M E Wagenlehner
Hospital St Elisabeth Straubing, Urologic Clinic, St Elisabeth Str 23, D 94315 Straubing, Germany
Expert Rev Anti Infect Ther 2:923-31. 2004
..In uncomplicated UTIs, antimicrobial therapy is usually empiric, whereas in complicated UTIs antibiotic therapy should be more individualized; tailored to the individual patient...
Antimicrobial treatment of prostatitisF Me Wagenlehner
Urologic Clinic, Hospital St Elisabeth Straubing, St Elisabeth Str 23, D 94315 Straubing, Germany
Expert Rev Anti Infect Ther 1:275-82. 2003
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Hospital-acquired urinary tract infectionsF M Wagenlehner
Urologic Clinic, Hospital St Elisabeth, Teaching Hospital of the Technical University Munich, St Elisabeth Str 23, D 94315, Straubing, Germany
J Hosp Infect 46:171-81. 2000
..Additionally the complicating factors must be diagnosed and treated adequately. The best prophylaxis is to minimize the duration of the urinary catheter and to employ general hygienic procedures...
Emergence of antibiotic resistance and prudent use of antibiotic therapy in nosocomially acquired urinary tract infectionsF M E Wagenlehner
Urologic Clinic, Hospital St Elisabeth, St Elisabeth Strasse 23, D 94315 Straubing, Germany
Int J Antimicrob Agents 23:S24-9. 2004
..Only those substances with high antibacterial activity, good bioavailability and those that are mainly excreted by the kidneys should be chosen and they have to be administered at sufficiently high doses...
Abdominal actinomycosisF M E Wagenlehner
First Department of Surgery, St Elisabeth, Straubing, Germany
Clin Microbiol Infect 9:881-5. 2003
..Even when infection had spread extensively, combined operative and antibiotic therapy cured most of the cases...
Clinically significant borderline resistance of sequential clinical isolates of Klebsiella pneumoniaeF M E Wagenlehner
Institute for Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany
Int J Antimicrob Agents 22:367-73. 2003
..Further increase of MIC to fluoroquinolones in vivo and in vitro was distinct. Kpn#1-SEL, selected in vitro, acquired a GyrA target mutation, whereas in Kpn#2 no known resistance mechanism could be detected...
Prostatitis: the role of antibiotic treatmentF M E Wagenlehner
Urologic Clinic, Hospital St Elisabeth, St Elisabeth Strasse 23, 94315 Straubing, Germany
World J Urol 21:105-8. 2003
..There is no consensus regarding the role of antibiotic treatment in patients with non-inflammatory CPPS (NIH category IIIB) and asymptomatic prostatitis (NIH category IV)...
[How should chronic recurrent cystitis be treated?]F M E Wagenlehner
Urologische Klinik, Klinikum St Elisabeth, Straubing
Dtsch Med Wochenschr 128:158. 2003
[Spectrum of pathogens and resistance to antibiotics in urinary tract infections and the consequences for antibiotic treatment: study of urology inpatients with urinary tract infections (1994-2001)]E Wagenlehner
Urologische Klinik, Klinikum St Elisabeth, Straubing
Urologe A 42:13-25. 2003
..To draw the correct conclusions from these data, the urologist must either be personally involved in the analytical procedure or receive the interim results promptly...
Molecular epidemiology and antibiotic resistance of Enterobacter spp. from three distinct populations in Grampian, UKF M E Wagenlehner
Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
Int J Antimicrob Agents 20:419-25. 2002
..Isolates (27%) were clonally related and typed in four clusters. Consecutive isolates were studied in selected patients showing minor genomic changes. One environmental isolate from a deep sink at ITU was related to a patient's isolate...
[Bacterial urinary tract infections--what is only an annoyance, when is risk involved?]F M E Wagenlehner
Urologische Klinik, Klinikum St Elisabeth, Straubing
Ther Umsch 59:464-8. 2002
..Therapy in uncomplicated UTI is essentially antibacterial, whereas in complicated UTI additional treatment of complicating factors is mandatory...
[Therapy of prostatitis syndrome]F M Wagenlehner
Urologische Klinik, Klinikum St Elisabeth, Akademisches Lehrkrankenhaus, Technische Universitat Munchen, St Elisabeth Strasse 23, 94315 Straubing
Urologe A 40:24-8. 2001
..It is important, however, to keep the patient fully informed about the diagnostic and therapeutic problems not to interfere with a trustful therapist-patient relationship...
Prospective, randomized, multicentric, open, comparative study on the efficacy of a prophylactic single dose of 500 mg levofloxacin versus 1920 mg trimethoprim/sulfamethoxazole versus a control group in patients undergoing TUR of the prostateF M E Wagenlehner
Urologic Clinic, Hospital St Elisabeth, St Elisabeth Str 23, D 94315 Straubing, Germany
Eur Urol 47:549-56. 2005
..The aims were to assess the rate of bacteriuria (cfu> or =10(4)/ml) 5 to 7 days, and 3 to 5 weeks after TUR-P, as well as postoperative complications...
Treatment of bacterial urinary tract infections: presence and futureFlorian M E Wagenlehner
Urologic Clinic, Hospital St Elisabeth, Straubing, Germany
Eur Urol 49:235-44. 2006
..Decrease the amount of antibiotics administered, optimal dosing, prevention of infection and development of new antibiotic substances. The aim of this review is to highlight the current and to describe future treatment options for UTIs...
Uraemia, psychosis, young patient: an uncommon link. Urinary tract and miliary tuberculosisFlorian M E Wagenlehner
Urology Clinic, St Elisabeth Hospital, D-94315 Straubing, Germany
Nephrol Dial Transplant 21:1113-6. 2006
Chlamydial infections in urologyFlorian M E Wagenlehner
Urologic Clinic, Hospital St Elisabeth, Straubing, Str 23, 94315 Straubing, Germany
World J Urol 24:4-12. 2006
..For treatment, only some antibiotics are effective because of the intracellular habitat of the pathogen. Prevention of infection comprises treatment and screening efforts...
Pharmacokinetics of ciprofloxacin XR (1000 mg) versus levofloxacin (500 mg) in plasma and urine of male and female healthy volunteers receiving a single oral doseFlorian M E Wagenlehner
Department of Urology, St Elisabeth Hospital, Straubing, Germany
Int J Antimicrob Agents 27:7-14. 2006
..Therefore, it can be assumed that the two doses investigated can be considered equivalent for the treatment of UTI...
[Therapy of the acute uncomplicated urinary tract infection]F Wagenlehner
Urologische Klinik, Klinikum St Elisabeth, St Elisabeth Strasse 23, 94315 Straubing
Urologe A 45:429-32, 434-5. 2006
..The Infectious Diseases Society of America (IDSA) developed evidence-based guidelines for the treatment of acute uncomplicated cystitis and acute uncomplicated pyelonephritis, which were recently updated by other expert groups...
[Guidelines for management of urinary tract infections in adults--an initiative]F Wagenlehner
Urologische Klinik, Klinikum St. Elisabeth, St.-Elisabeth-Strasse 23, 94315, Straubing
Urologe A 45:464-6. 2006
Asymptomatic bacteriuria in elderly patients: significance and implications for treatmentFlorian M E Wagenlehner
Department of Urology, University of Giessen, Giessen, Germany
Drugs Aging 22:801-7. 2005
..Therefore, until the implications of the bacteria involved in ASB are fully understood, implementing the same hygienic precautions as are used in individuals with symptomatic UTIs should at least be undertaken...
The role of antibiotics in chronic bacterial prostatitisF M E Wagenlehner
Urologic Clinic, Hospital St Elisabeth Straubing, St Elisabeth Str 23, D 94315 Straubing, Germany
Int J Antimicrob Agents 26:1-7. 2005
..Nevertheless, the concentrations at the site of infection of most of the fluoroquinolones should be sufficient for the treatment of CBP and vesiculitis caused by susceptible pathogens...
Emerging drugs for bacterial urinary tract infectionsFlorian M E Wagenlehner
Urologic Clinic, Hospital St Elisabeth, St Elisabeth Street 23, D 94315 Straubing, Germany
Expert Opin Emerg Drugs 10:275-98. 2005
..The aim of this review is to highlight the existing, and to describe emerging, treatment options for UTIs...
Emergence of antibiotic resistance amongst hospital-acquired urinary tract infections and pharmacokinetic/pharmacodynamic considerationsF M E Wagenlehner
Urologic Clinic, Hospital St Elisabeth Straubing, St Elisabeth Str 23, D 94315 Straubing, Germany
J Hosp Infect 60:191-200. 2005
..The emergence of resistance can possibly be lowered by adequate drug selection and dosing. Increasing antibiotic resistance requires more prudent use of antimicrobial drugs...
Antimicrobials in urogenital infectionsFlorian M E Wagenlehner
Department of Urology, Pediatric Urology and Andrology, Justus Liebig University, Giessen, Germany
Int J Antimicrob Agents 38:3-10. 2011
..Furthermore in genital infections fastidious organisms, such as Chlamydia or Mycoplasma spp. have to be considered with respect to their antimicrobial susceptibility...
Urosepsis--from the view of the urologistFlorian M E Wagenlehner
Urologic Clinic, Justus Liebig University Giessen, Germany
Int J Antimicrob Agents 38:51-7. 2011
..Dosage of an antibiotic in the septic patient generally has to be high to ensure adequate pharmacological exposure in the individual patient...
Current challenges in the treatment of complicated urinary tract infections and prostatitisF M E Wagenlehner
Department of Urology, Hospital St. Elisabeth, Straubing, Germany
Clin Microbiol Infect 12:67-80. 2006
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[Recurrent urinary tract infections should not be treated cavalierly. First verify the diagnosis!]F M E Wagenlehner
Urologische Klinik, Klinikum St Elisabeth, Straubing
MMW Fortschr Med 145:37-9. 2003
..For the prevention of recurrent UTI, antibiotics, functional foods, injections, probiotic agents and other measures are recommended with varying potential for success...
Acute bacterial prostatitis and chronic prostatitis/chronic pelvic pain syndrome: andrological implicationsW Weidner
Department of Urology and Paediatric Urology, University of Giessen, Giessen, Germany
Andrologia 40:105-12. 2008
..CP/CPPS therapy has the goal to reduce pelvic pain. However, treatment regimens are not as standardised. Andrological side-effects are well defined and mainly due to the functional background of these agents...
Fluoroquinolone antimicrobial agents in the treatment of prostatitis and recurrent urinary tract infections in menF M E Wagenlehner
Urologic Clinic, Hospital St. Elisabeth Straubing, St. Elisabeth Str. 23, D-94315 Straubing, Germany
Curr Urol Rep 5:309-16. 2004
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Spectrum and antibiotic resistance of uropathogens from hospitalized patients with urinary tract infections: 1994-2000F M E Wagenlehner
Department of Urology, Hospital St. Elisabeth, Straubing, Germany
Int J Antimicrob Agents 19:557-64. 2002
..Ciprofloxacin was the best oral antibiotic for the empirical treatment of urinary tract infection (UTI) due to Gram-negative rods and ampicillin/sulbactam for the treatment of UTI with Gram-positive cocci...
Epidemiological analysis of the spread of pathogens from a urological ward using genotypic, phenotypic and clinical parametersF M E Wagenlehner
Urologic Clinic, St. Elisabeth Hospital, St. Elisabeth Strasse 23, D-94315 Straubing, Germany
Int J Antimicrob Agents 19:583-91. 2002
..Altogether, there was a high rate of clonal relationship amongst uropathogens in our urological ward and we conclude that hygienic means and measures are far from being optimal...
New drugs for Gram-positive uropathogensF M E Wagenlehner
Department of Urology, Hospital St. Elisabeth, St. Elisabeth Strasse 23, D-94315 Straubing, Germany
Int J Antimicrob Agents 24:S39-43. 2004
..The pharmacokinetics and the mode of action of these two antibiotics are discussed together with some clinical data in the context of therapeutic use in patients with complicated UTIs...
[Urosepsis and treatment]F M E Wagenlehner
Klinik und Poliklinik fur Urologie, Kinderurologie und Andrologie, Universitätsklinikum Giessen und Marburg GmbH Standort Giessen, Justus Liebig Universitat, Rudolf Buchheim Strasse 7, 35385, Giessen, Deutschland
Urologe A 49:618-22. 2010
..The intensive care of the septic patient needs to be started as early as on patient admission and, where necessary, continued on the intensive care ward...
[Urogenital infections in the elderly]W Weidner
Klinik und Poliklinik für Urologie und Kinderurologie, Justus Liebig Universitat Giessen, Rudolf Buchheim Strasse 7, 35385 Giessen
Urologe A 41:328-32. 2002
..Urologic implications resulting from this set of difficulties have not yet been investigated sufficiently and need further evidence-based work-up...
In vitro activity of daptomycin versus linezolid and vancomycin against gram-positive uropathogens and ampicillin against enterococci, causing complicated urinary tract infectionsFlorian M E Wagenlehner
Department of Urology, St. Elisabeth Hospital, Straubing, Germany
Chemotherapy 51:64-9. 2005
..Thus, daptomycin should be evaluated in a clinical study...
[Chlamydia infections of the male: what is relevant for urologists?]W Weidner
Klinik und Poliklinik für Urologie und Kinderurologie, Justus Liebig Universitat, Rudolf Buchheim Strasse 7, 35292 Giessen, Deutschland
Urologe A 45:1504-8. 2006
..This review summarizes the most current developments in the diagnostics and therapeutical approaches in Chlamydia infections of the male accessory sex glands...