Nobuyuki Wada

Summary

Publications

  1. ncbi request reprint Overexpression of the mitotic spindle assembly checkpoint genes hBUB1, hBUBR1 and hMAD2 in thyroid carcinomas with aggressive nature
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University, 3 9 Fukuura, Kanazawa Ku, Yokohama City, Kanagawa, Japan
    Anticancer Res 28:139-44. 2008
  2. doi request reprint Recommendation for subclass evaluation of TNM stage iva papillary thyroid carcinomas: T4aN1b patients are at risk for recurrence and survival
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University Hospital and Medical Center, 3 9 Fukuura, Kanazawa Ku, Yokohama City, Kanagawa, 236 0004, Japan
    Ann Surg Oncol 15:1511-7. 2008
  3. ncbi request reprint Clinical outcomes in older or younger patients with papillary thyroid carcinoma: impact of lymphadenopathy and patient age
    N Wada
    Department of General Surgery, Yokohama City University Hospital and Medical Center, 3 9 Fukuura, Kanazawa Ku, Yokohama City, Kanagawa 236 0004, Japan
    Eur J Surg Oncol 34:202-7. 2008
  4. ncbi request reprint Microscopic regional lymph node status in papillary thyroid carcinoma with and without lymphadenopathy and its relation to outcomes
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University Hospital and Medical Center, 3 9 Fukuura, Kanazawa Ku, Yokohama City, Kanagawa, 236 0004 Japan
    Langenbecks Arch Surg 392:417-22. 2007
  5. ncbi request reprint Clinical outcome by AMES risk definition in Japanese differentiated thyroid carcinoma patients
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University, Yokohama City, Kanagawa, Japan
    Asian J Surg 30:102-7. 2007
  6. pmc Pediatric differentiated thyroid carcinoma in stage I: risk factor analysis for disease free survival
    Nobuyuki Wada
    Surgical Branch, Ito Hospital, 4 3 6 Jingumae, Shibuya ku, Tokyo 150 8308, Japan
    BMC Cancer 9:306. 2009
  7. ncbi request reprint Prognostic value of the sixth edition AJCC/UICC TNM classification for differentiated thyroid carcinoma with extrathyroid extension
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University Hospital and Medical Center, 3 9 Fukuura, Yokohama City, Kanagawa 236 0004, Japan
    J Clin Endocrinol Metab 92:215-8. 2007
  8. ncbi request reprint Clinical outcome of different modes of resection in papillary thyroid carcinomas with laryngotracheal invasion
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University, 3 9 Fukuura, Kanazawa ku Yokohama, Kanagawa 236 0004, Japan
    Langenbecks Arch Surg 391:545-9. 2006
  9. doi request reprint Treatment strategy of papillary thyroid carcinoma in children and adolescents: clinical significance of the initial nodal manifestation
    Nobuyuki Wada
    Surgical Branch, Ito Hospital, Tokyo, Japan
    Ann Surg Oncol 16:3442-9. 2009
  10. pmc Superior vena cava (SVC) reconstruction using autologous tissue in two cases of differentiated thyroid carcinoma presenting with SVC syndrome
    Nobuyuki Wada
    Department of Surgery, Yokohama City University Hospital, 3 9 Fukuura, Kanazawa Ku, Yokohama City, Kanagawa 236 0004, Japan
    World J Surg Oncol 7:75. 2009

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Overexpression of the mitotic spindle assembly checkpoint genes hBUB1, hBUBR1 and hMAD2 in thyroid carcinomas with aggressive nature
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University, 3 9 Fukuura, Kanazawa Ku, Yokohama City, Kanagawa, Japan
    Anticancer Res 28:139-44. 2008
    ..MSAC gene expressions have been reported to be associated with tumor cell proliferation or unfavorable cancer behavior. The present study was conducted to preliminary investigate the MSAC gene expressions in thyroid neoplasms...
  2. doi request reprint Recommendation for subclass evaluation of TNM stage iva papillary thyroid carcinomas: T4aN1b patients are at risk for recurrence and survival
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University Hospital and Medical Center, 3 9 Fukuura, Kanazawa Ku, Yokohama City, Kanagawa, 236 0004, Japan
    Ann Surg Oncol 15:1511-7. 2008
    ..Although all tumor, node, metastasis system (TNM) stage IVA papillary thyroid carcinomas (PTCs) do not seem to behave equivalently as a result of various tumor and node stages, to our knowledge, subclass evaluation has never been attempted...
  3. ncbi request reprint Clinical outcomes in older or younger patients with papillary thyroid carcinoma: impact of lymphadenopathy and patient age
    N Wada
    Department of General Surgery, Yokohama City University Hospital and Medical Center, 3 9 Fukuura, Kanazawa Ku, Yokohama City, Kanagawa 236 0004, Japan
    Eur J Surg Oncol 34:202-7. 2008
    ..To examine lymph node metastasis (LNM) from papillary thyroid carcinoma (PTC) according to clinicopathological features and outcomes associated with the nodal status...
  4. ncbi request reprint Microscopic regional lymph node status in papillary thyroid carcinoma with and without lymphadenopathy and its relation to outcomes
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University Hospital and Medical Center, 3 9 Fukuura, Kanazawa Ku, Yokohama City, Kanagawa, 236 0004 Japan
    Langenbecks Arch Surg 392:417-22. 2007
    ..The aim of this study was to evaluate microscopic nodal status in papillary thyroid carcinoma (PTC) with and without lymphadenopathy and its relation to outcomes...
  5. ncbi request reprint Clinical outcome by AMES risk definition in Japanese differentiated thyroid carcinoma patients
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University, Yokohama City, Kanagawa, Japan
    Asian J Surg 30:102-7. 2007
    ..This study aimed to analyse whether age, metastasis, extrathyroidal invasion and size (AMES) risk definition is valuable for Japanese patients with differentiated thyroid carcinoma (DTC)...
  6. pmc Pediatric differentiated thyroid carcinoma in stage I: risk factor analysis for disease free survival
    Nobuyuki Wada
    Surgical Branch, Ito Hospital, 4 3 6 Jingumae, Shibuya ku, Tokyo 150 8308, Japan
    BMC Cancer 9:306. 2009
    ....
  7. ncbi request reprint Prognostic value of the sixth edition AJCC/UICC TNM classification for differentiated thyroid carcinoma with extrathyroid extension
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University Hospital and Medical Center, 3 9 Fukuura, Yokohama City, Kanagawa 236 0004, Japan
    J Clin Endocrinol Metab 92:215-8. 2007
    ..The prognostic value of the sixth edition AJCC/UICC TNM classification is currently unclear...
  8. ncbi request reprint Clinical outcome of different modes of resection in papillary thyroid carcinomas with laryngotracheal invasion
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University, 3 9 Fukuura, Kanazawa ku Yokohama, Kanagawa 236 0004, Japan
    Langenbecks Arch Surg 391:545-9. 2006
    ..The aim of this study is to evaluate the outcome of different modes of resection in papillary thyroid carcinoma (PTC) with laryngotracheal invasion...
  9. doi request reprint Treatment strategy of papillary thyroid carcinoma in children and adolescents: clinical significance of the initial nodal manifestation
    Nobuyuki Wada
    Surgical Branch, Ito Hospital, Tokyo, Japan
    Ann Surg Oncol 16:3442-9. 2009
    ..Risk factors and treatment strategy in younger patients with papillary thyroid carcinoma are still controversial...
  10. pmc Superior vena cava (SVC) reconstruction using autologous tissue in two cases of differentiated thyroid carcinoma presenting with SVC syndrome
    Nobuyuki Wada
    Department of Surgery, Yokohama City University Hospital, 3 9 Fukuura, Kanazawa Ku, Yokohama City, Kanagawa 236 0004, Japan
    World J Surg Oncol 7:75. 2009
    ..However, SVC reconstruction using autologous tissue in thyroid carcinoma has not been reported to date. To our knowledge, this is the first report describing such an unusual technique in DTC patients...
  11. ncbi request reprint Detection of gastric cancer cells in the blue lymph node and lymphaticus under sentinel lymph node biopsy using dye technique alone
    Yasushi Rino
    Department of Surgery, Yokohama City University, School of Medicine, 3 9, Fukuura, Kanazawa Ku, Yokohama 236 0004, Japan
    Hepatogastroenterology 57:395-7. 2010
    ..We investigated whether or not there are cancer cells in the blue node (BN) and the sentinel lymphaticus (SL), which is detected using sentinel node biopsy (SNB)...
  12. ncbi request reprint Clinical significance of BRAF (V600E) mutation and Ki-67 labeling index in papillary thyroid carcinomas
    Hirotaka Nakayama
    Department of General Surgery, Yokohama City University Hospital, 3 9 Fukuura, Kanazawa Ku, Yokohama 236 0004, Japan
    Anticancer Res 27:3645-9. 2007
    ..Activating mutations of the BRAF gene have recently been reported in thyroid carcinomas. In particular, V600E mutation is highly prevalent in papillary thyroid carcinoma (PTC)...
  13. ncbi request reprint Axillary lymph node metastasis from papillary thyroid carcinoma: report of a case
    Hirotaka Nakayama
    Department of Surgery, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama, 236 0004, Japan
    Surg Today 37:311-5. 2007
    ..Axillary LNM from PTC is unusual and seems to be associated with a poor prognosis. Thus, comprehensive treatment strategies are needed to improve the outcome of patients with PTC who present with axillary LNM...
  14. pmc Primary placement technique of jejunostomy using the entristar™ skin-level gastrostomy tube in patients with esophageal cancer
    Yasushi Rino
    Department of Surgery, Yokohama City University, School of Medicine 3 9, Fukuura, Kanazawa Ku, Yokohama City, 236 0004, Japan
    BMC Gastroenterol 11:8. 2011
    ..We describe the procedure and the adverse effects of SLJT in patients with esophageal cancer (EC)...
  15. doi request reprint Lung cancer associated with Sweet's syndrome: report of a case
    Hiromasa Arai
    Department of General Surgery, Yokohama City University School of Medicine, Yokohama, Japan
    Surg Today 38:639-43. 2008
    ..The patient was discharged from the hospital without any worsening of Sweet's syndrome. We herein report a first operative case of an early stage lung adenocarcinoma with this syndrome...
  16. doi request reprint Successful treatment of adrenocortical carcinoma with pulmonary metastasis in a child: report of a case
    Hiromasa Arai
    Department of General Surgery, Yokohama City University School of Medicine, 3 9 Fukuura Kanazawa ku, Yokohama, 236 0004, Japan
    Surg Today 38:965-9. 2008
    ..After bilateral lung surgery for the metastatic lesions, the plasma dehydroepiandrosterone sulfate level became negative...
  17. pmc Phase II Study of S-1 Monotherapy as a First-line, Combination Therapy of S-1 plus Cisplatin as a Second-line, and Weekly Paclitaxel Monotherapy as a Third-line Therapy in Patients with Advanced Gastric Carcinoma: Phase II Study of S-1, S-1 plus Cisplatin
    Yasushi Rino
    Department of Surgery, School of Medicine, Yokohama City University
    Clin Med Oncol 2:375-83. 2008
    ..We conducted a pilot phase II study to evaluate the efficacy and safety of S-1 as a first-line, S-1 plus cisplatin as a second-line, and weekly paclitaxel as a third-line therapy for advanced gastric cancer...
  18. pmc Lymph node metastasis from 259 papillary thyroid microcarcinomas: frequency, pattern of occurrence and recurrence, and optimal strategy for neck dissection
    Nobuyuki Wada
    First Department of Surgery, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan
    Ann Surg 237:399-407. 2003
    ..To determine the frequency and pattern of lymph node metastasis (LNM) from papillary thyroid microcarcinoma (PTMC) and the results of node dissection, and to establish the optimal strategy for neck dissection in these patients...
  19. pmc A Phase II Study of S-1 Monotherapy as a First-line Combination Therapy of S-1 Plus Cisplatin as a Second-line Therapy, and Weekly Paclitaxel Monotherapy as a Third-line Therapy in Patients with Advanced Gastric Carcinoma: A Second Report
    Yasushi Rino
    Department of Surgery, School of Medicine, Yokohama City University
    Clin Med Insights Oncol 4:1-10. 2010
    ..Since then, we have calculated the MST for this study and herein report our findings...
  20. ncbi request reprint Solitary metachronous metastasis to the thyroid from renal clear cell carcinoma 19 years after nephrectomy: report of a case
    Nobuyuki Wada
    Department of General Surgery, Yokohama City University Medical Center, 4 57 Urafune cho, Yokohama, 232 0024, Japan
    Surg Today 35:483-7. 2005
    ..Thus, the possibility of late RCC metastasis to the thyroid should be considered, even in a patient with a remote history. Furthermore, TTF-1 is useful for identifying thyroid metastatic carcinomas...
  21. ncbi request reprint Changes in vitamin D after gastrectomy
    Yasushi Rino
    Department of Surgery, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama, 236 0004, Japan
    Gastric Cancer 10:228-33. 2007
    ..Accordingly, we performed the present study to obtain evidence supporting the effectiveness of 1alpha hydroxy vitamin D3 in post-gastrectomy patients...
  22. ncbi request reprint Long-term outcome after hernia repair with the prolene hernia system
    Shinichi Hasegawa
    Department of General Surgery, Yokohama City General Medical Center, 4 57 Urafune cho, Minami Ku, Yokohama, Kanagawa 232 0024, Japan
    Surg Today 36:1058-62. 2006
    ..We evaluated the long-term outcome and symptoms after inguinal hernia repair using the Prolene Hernia System (PHS)...
  23. ncbi request reprint Grade I lymphomatoid granulomatosis with increased uptake of [18F] fluorodeoxyglucose in positron emission tomography: a case report
    Hiromasa Arai
    Department of Surgery, Yokohama City University, School of Medicine
    J Clin Exp Hematop 49:39-44. 2009
    ..The patient had no previous symptoms. A tumor biopsy was performed and the histological diagnosis was grade I LYG. Therefore, increased SUV(max) in FDG-PET might be useful for diagnosing of LYG...
  24. ncbi request reprint Postoperative changes in thyrotropin-binding inhibitory immunoglobulin level in patients with Graves' disease: is subtotal thyroidectomy a suitable therapeutic option for patients of childbearing age with Graves' disease?
    K Sugino
    Department of Surgery, Ito Hospital, 4 3 6 Jingumae, Shibuya ku, Tokyo 150 8308, Japan
    World J Surg 23:727-31. 1999
    ..It should be noted that a few patients achieved hormonal remission but not immunologic remission...
  25. ncbi request reprint Surgery for gastric carcinoma in patients more than 85 years of age
    Y Otani
    Department of Surgery, School of Medicine, Keio University Tokyo, Japan
    J Gastroenterol Hepatol 15:507-11. 2000
    ..It has not been determined whether surgery improves the quality of life or prolongs survival in patients older than 85 years. This study was designed to evaluate surgery as a treatment option in patients more than 85 years of age...
  26. ncbi request reprint Chromosomal aberrations by comparative genomic hybridization in hürthle cell thyroid carcinomas are associated with tumor recurrence
    Nobuyuki Wada
    Department of Surgery, University of California, San Francisco, San Francisco, California 94143, USA
    J Clin Endocrinol Metab 87:4595-601. 2002
    ..Such chromosomal aberrations may be predictive for recurrent disease in patients with Hürthle cell thyroid carcinoma...
  27. ncbi request reprint Anaplastic thyroid cancer: cytogenetic patterns by comparative genomic hybridization
    Daishu Miura
    Department of Surgery, University of California, San Francisco Mount Zion Medical Center, San Francisco, California 94143 1674, USA
    Thyroid 13:283-90. 2003
    ..These findings support the concept that PTC and FTC have different genetic backgrounds and, even after the transformation to ATC, they may retain some of their cytogenetic characteristics...
  28. ncbi request reprint Chromosomal aberrations by comparative genomic hybridization in thyroid tumors in patients with familial nonmedullary thyroid cancer
    Laurent Brunaud
    Endocrine Surgical Oncology Fellow, University of California San Francisco UCSF Mount Zion Medical Center, San Francisco, California 94143, USA
    Thyroid 13:621-9. 2003
    ..However, the genetic background of FNMTC is still poorly understood and the causative gene(s) have not yet been identified...
  29. ncbi request reprint Incision length for standard thyroidectomy and parathyroidectomy: when is it minimally invasive?
    Laurent Brunaud
    Department of Surgery, University of California, San Francisco, USA
    Arch Surg 138:1140-3. 2003
    ..Current techniques for open conventional thyroidectomy or parathyroidectomy have evolved to enable a shorter incision (main proposition), and the length of the incision is influenced by objective factors...
  30. ncbi request reprint Overexpression of EphA4 gene and reduced expression of EphB2 gene correlates with liver metastasis in colorectal cancer
    Takashi Oshima
    Gastroenterological Center, Yokohama City University Medical Center, Minami Ku, Yokohama shi, Kanagawa ken 232 0024, Japan
    Int J Oncol 33:573-7. 2008
    ..Overexpression of the EphA4 gene and reduced expression of the EphB2 gene may thus be a useful predictor of liver metastasis in patients with colorectal cancer...
  31. ncbi request reprint [A case of long-term survival of 5 years after operation and chemotherapy for type 4 gastric cancer with peritoneal dissemination]
    Takanobu Yamada
    Dept of Surgery, Yokohama City University, School of Medicine
    Gan To Kagaku Ryoho 35:117-9. 2008
    ..Now the patient is undergoing weekly paclitaxel. The S-1 plus PSK therapy is able to prolong time to progression and has fewer adverse effects...
  32. ncbi request reprint Reduced expression of the claudin-7 gene correlates with venous invasion and liver metastasis in colorectal cancer
    Takashi Oshima
    Gastroenterological Center, Yokohama City University Medical Center, Kanagawa ken 232 0024, Japan
    Oncol Rep 19:953-9. 2008
    ..Reduced expression of the claudin-7 gene may thus be a useful predictor of liver metastasis in patients with colorectal cancer...