[Depressive symptoms, cortisol, visceral fat and metabolic syndrome]N Vogelzangs
VU Medisch Centrum, Amsterdam
Tijdschr Psychiatr 53:613-20. 2011
..Metabolic syndrome might explain the relationship between depression and cardiovascular disease...
Obesity and onset of significant depressive symptoms: results from a prospective community-based cohort study of older men and womenNicole Vogelzangs
Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, AJ Ernststraat 887, 1081 HL Amsterdam, Netherlands
J Clin Psychiatry 71:391-9. 2010
..We prospectively examined whether obesity (specifically, abdominal) increased the risk of onset of depression in a population-based sample of older persons...
Late-life depression, cortisol, and the metabolic syndromeNicole Vogelzangs
Department of Psychiatry, VU University Medical Center, A J Ernststraat 887, Amsterdam, The Netherlands
Am J Geriatr Psychiatry 17:716-21. 2009
..This study investigated cross-sectionally whether depression and high-cortisol levels increased the odds of metabolic syndrome in an older community-based sample...
- Comorbidity and risk indicators for alcohol use disorders among persons with anxiety and/or depressive disorders: findings from the Netherlands Study of Depression and Anxiety (NESDA)
Lynn Boschloo
Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
J Affect Disord 131:233-42. 2011
..This study examines comorbidity of alcohol abuse and alcohol dependence as well as its risk indicators among anxious and/or depressed persons, also considering temporal sequencing of disorders...
- Heavy alcohol use, rather than alcohol dependence, is associated with dysregulation of the hypothalamic-pituitary-adrenal axis and the autonomic nervous system
Lynn Boschloo
Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
Drug Alcohol Depend 116:170-6. 2011
..However, the relative contribution of alcohol use and AD is unclear...
- Psychosocial risk factors and the metabolic syndrome in elderly persons: findings from the Health, Aging and Body Composition study
Nicole Vogelzangs
Department of Psychiatry and Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands
J Gerontol A Biol Sci Med Sci 62:563-9. 2007
..This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons...
- Depressive symptoms and change in abdominal obesity in older persons
Nicole Vogelzangs
Department of Psychiatry and EMGO Institute, VU University Medical Center, A J Ernststraat 887, 1081 HL Amsterdam, The Netherlands
Arch Gen Psychiatry 65:1386-93. 2008
..Depression has been hypothesized to result in abdominal obesity through the accumulation of visceral fat. No large study has tested this hypothesis longitudinally...
- Alcohol use disorders and the course of depressive and anxiety disorders
Lynn Boschloo
Department of Psychiatry, VU University Medical Centre, Amsterdam, The Netherlands
Br J Psychiatry 200:476-84. 2012
..Inconsistent findings have been reported on the role of comorbid alcohol use disorders as risk factors for a persistent course of depressive and anxiety disorders...
- Predictors of the 2-year recurrence and persistence of alcohol dependence
Lynn Boschloo
Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
Addiction 107:1639-40. 2012
..To identify independent risk factors of the recurrence of alcohol dependence (AD) in people with a remitted disorder at baseline and persistence of AD in people with a current disorder at baseline...
- Leptin, abdominal obesity, and onset of depression in older men and women
Yuri Milaneschi
Department of Psychiatry, VU University Medical Center GGZ inGeest, A J Ernststraat 1187, 1081 HL Amsterdam, The Netherlands
J Clin Psychiatry 73:1205-11. 2012
..We tested whether high circulatory concentration of leptin, alone and in combination with visceral adiposity, is associated with onset of depression in a sample of older persons...
- Insomnia and sleep duration in a large cohort of patients with major depressive disorder and anxiety disorders
Josine G van Mill
NeuroCampus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
J Clin Psychiatry 71:239-46. 2010
....
- Metabolic depression: a chronic depressive subtype? Findings from the InCHIANTI study of older persons
Nicole Vogelzangs
Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
J Clin Psychiatry 72:598-604. 2011
..However, such a longitudinal link has not yet been confirmed. This study examines whether metabolic syndrome or its components are associated with onset and chronicity of depression...
- Cardiovascular disease in persons with depressive and anxiety disorders
Nicole Vogelzangs
Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
J Affect Disord 125:241-8. 2010
..In addition, the role of specific clinical characteristics of depressive and anxiety disorders in the association with cardiovascular disease was explored...
- The impact of stress systems and lifestyle on dyslipidemia and obesity in anxiety and depression
Arianne K B van Reedt Dortland
Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands Electronic address
Psychoneuroendocrinology 38:209-18. 2013
..We aimed to elucidate whether biological stress systems or lifestyle factors underlie these associations. If so, they may be useful targets for CVD prevention and intervention...
- Dysregulation of the autonomic nervous system and its association with the presence and intensity of chronic widespread pain
Ansam Barakat
VU University Medical Center, Amsterdam, The Netherlands
Arthritis Care Res (Hoboken) 64:1209-16. 2012
..To test the hypotheses that dysregulation of the autonomic nervous system (ANS) is associated with the presence of chronic widespread pain (CWP), and that dysregulation of the ANS is associated with higher pain intensity in CWP...
- Urinary cortisol and six-year risk of all-cause and cardiovascular mortality
Nicole Vogelzangs
Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
J Clin Endocrinol Metab 95:4959-64. 2010
..The stress hormone cortisol has been linked with unfavorable cardiovascular risk factors, but longitudinal studies examining whether high levels of cortisol predict cardiovascular mortality are largely absent...
- Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal axis activity is associated with metabolic abnormalities
Carmilla M M Licht
Department of Psychiatry EMGO Institute, Vrije Universiteit Medical Center, AJ Ernststraat 887, 1081 HL Amsterdam, The Netherlands
J Clin Endocrinol Metab 95:2458-66. 2010
..Stress is suggested to lead to metabolic dysregulations as clustered in the metabolic syndrome, but the underlying biological mechanisms are not yet well understood...
- Associations between sex steroid hormone levels and depressive symptoms in elderly men and women: results from the Health ABC study
Lisette F J Morsink
EMGO Institute Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
Psychoneuroendocrinology 32:874-83. 2007
..This study investigates the association between total testosterone, free testosterone, and DHEAS levels with depressive symptoms in a well-functioning elderly population...
- Depressive and anxiety disorders and risk of subclinical atherosclerosis Findings from the Netherlands Study of Depression and Anxiety (NESDA)
Adrie Seldenrijk
Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
J Psychosom Res 69:203-10. 2010
..The present study examined whether subclinical atherosclerosis was more prevalent in a large cohort of persons with depressive or anxiety disorders as compared to non-depressed and non-anxious controls...
- Impact of pain on the course of depressive and anxiety disorders
Marloes M J G Gerrits
Department of Psychiatry, EMGO Institute for Health and Care Research, VU University Medical Center and Academic Outpatient Clinic for Affective Disorders, GGZ inGeest, Amsterdam, The Netherlands
Pain 153:429-36. 2012
..More attention to pain seems to be necessary when diagnosing and treating these disorders. Future research should focus on treatment modalities for this co-occurrence, with joint pain in particular...
- The performance of the Alcohol Use Disorder Identification Test (AUDIT) in detecting alcohol abuse and dependence in a population of depressed or anxious persons
Lynn Boschloo
Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, AJ Ernststraat 887, 1081 HL Amsterdam, The Netherlands
J Affect Disord 126:441-6. 2010
..This study examines the performance of the Alcohol Use Disorder Identification Test (AUDIT) in detecting alcohol abuse and dependence in this high-risk group and compares it to that in healthy controls...
- Hypercortisolemic depression is associated with the metabolic syndrome in late-life
Nicole Vogelzangs
Department of Psychiatry and EMGO Institute, VU University Medical Center, Oldenaller 1, 1081 HJ Amsterdam, The Netherlands
Psychoneuroendocrinology 32:151-9. 2007
..Such a link could be due to increased HPA-axis activity. This study investigates the cross-sectional relationship between depression, urinary cortisol and metabolic syndrome in an older population...
- Physical function as predictor for the persistence of depressive and anxiety disorders
Bianca A van Milligen
Department of Psychiatry, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
J Affect Disord 136:828-32. 2012
..Depressive and anxiety disorders often involve a chronic course. This study examined whether objective physical function is a predictor for the persistence of depressive and anxiety disorders...
- Comparing cognitive and somatic symptoms of depression in myocardial infarction patients and depressed patients in primary and mental health care
Nynke A Groenewold
Interdisciplinary Center for Psychopathology and Emotion regulation, Department of Psychiatry, University Medical Center Groningen, Groningen, The Netherlands
PLoS ONE 8:e53859. 2013
..Future studies should investigate the etiological factors predictive of symptom dimensions in myocardial infarction and late-onset depression patients...
- Differential mortality rates in major and subthreshold depression: meta-analysis of studies that measured both
Pim Cuijpers
Department of Clinical Psychology, VU University Amsterdam, Amsterdam, The Netherlands
Br J Psychiatry 202:22-7. 2013
..Although the association between depression and excess mortality has been well established, it is not clear whether this is greater in major depression than in subthreshold depression...
