Jamboor K Vishwanatha

Summary

Publications

  1. pmc Breast cancer disparities: Frontline strategies, proceedings of the 7(th) annual texas conference on health disparities
    Marilyne Kpetemey
    Texas Center for Health Disparities, Institute for Cancer Research, University of North Texas Health Science Center, Fort Worth, Texas, USA
    J Carcinog 11:16. 2012
  2. pmc Effect of down-regulation of aquaporins in human corneal endothelial and epithelial cell lines
    Jwalitha Shankardas
    Department of Biomedical Sciences, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Mol Vis 16:1538-48. 2010
  3. pmc Reciprocal regulation of annexin A2 and EGFR with Her-2 in Her-2 negative and herceptin-resistant breast cancer
    Praveenkumar K Shetty
    Department of Biochemistry, SDM College of Medical Sciences and Hospital, Dharwad, India
    PLoS ONE 7:e44299. 2012
  4. pmc Mitigating prolonged QT interval in cancer nanodrug development for accelerated clinical translation
    Amalendu P Ranjan
    Department of Molecular Biology and Immunology and Institute for Cancer Research, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
    J Nanobiotechnology 11:40. 2013
  5. ncbi request reprint Establishment of human retinal microvascular endothelial cells with extended life-span
    Meghana V Kashyap
    Professor and Dean, UNT Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, Texas 76107, U S A
    In Vivo 27:685-94. 2013
  6. ncbi request reprint Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: inhibition of tumor growth and angiogenesis
    Amalendu P Ranjan
    Department of Molecular Biology and Immunology, and Institute for Cancer Research, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, Texas, 76107, USA
    Anticancer Res 33:3603-9. 2013
  7. ncbi request reprint Combinatorial nanoparticles for cancer diagnosis and therapy
    A Mukerjee
    Department of Molecular Biology and Immunology, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
    Curr Med Chem 19:3714-21. 2012
  8. ncbi request reprint Efficient nanoparticle mediated sustained RNA interference in human primary endothelial cells
    Anindita Mukerjee
    Department of Molecular Biology and Immunology, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Nanotechnology 22:445101. 2011
  9. pmc Scale up, optimization and stability analysis of Curcumin C3 complex-loaded nanoparticles for cancer therapy
    Amalendu P Ranjan
    Department of Molecular Biology and Immunology and Institute for Cancer Research, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    J Nanobiotechnology 10:38. 2012
  10. doi request reprint Signal transducer and activator of transcription 6 (STAT6) is a novel interactor of annexin A2 in prostate cancer cells
    Susobhan Das
    Department of Molecular Biology and Immunology and Institute for Cancer Research, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
    Biochemistry 49:2216-26. 2010

Collaborators

Detail Information

Publications28

  1. pmc Breast cancer disparities: Frontline strategies, proceedings of the 7(th) annual texas conference on health disparities
    Marilyne Kpetemey
    Texas Center for Health Disparities, Institute for Cancer Research, University of North Texas Health Science Center, Fort Worth, Texas, USA
    J Carcinog 11:16. 2012
    ..This article summarizes the proceedings of the meeting providing salient strategies and best practices presented by the speakers...
  2. pmc Effect of down-regulation of aquaporins in human corneal endothelial and epithelial cell lines
    Jwalitha Shankardas
    Department of Biomedical Sciences, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Mol Vis 16:1538-48. 2010
    ....
  3. pmc Reciprocal regulation of annexin A2 and EGFR with Her-2 in Her-2 negative and herceptin-resistant breast cancer
    Praveenkumar K Shetty
    Department of Biochemistry, SDM College of Medical Sciences and Hospital, Dharwad, India
    PLoS ONE 7:e44299. 2012
    ..Targeting this AnxA2 dependent positive regulation of EGFR signaling cascade may be of therapeutic value in Her-2 negative breast cancer...
  4. pmc Mitigating prolonged QT interval in cancer nanodrug development for accelerated clinical translation
    Amalendu P Ranjan
    Department of Molecular Biology and Immunology and Institute for Cancer Research, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
    J Nanobiotechnology 11:40. 2013
    ..In our previous studies, we found that lipids have protective actions against hERG channel inhibition and therefore QT prolongation...
  5. ncbi request reprint Establishment of human retinal microvascular endothelial cells with extended life-span
    Meghana V Kashyap
    Professor and Dean, UNT Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, Texas 76107, U S A
    In Vivo 27:685-94. 2013
    ..To generate and characterize a telomerase-immortalized human retinal microvascular endothelial cell (HREC) line. This cell line may be utilized as an in vitro model to study the molecular basis of several diseases of the human retina...
  6. ncbi request reprint Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: inhibition of tumor growth and angiogenesis
    Amalendu P Ranjan
    Department of Molecular Biology and Immunology, and Institute for Cancer Research, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, Texas, 76107, USA
    Anticancer Res 33:3603-9. 2013
    ..The major disadvantage associated with curcumin, a potent anticancer agent, is its poor aqueous solubility and hence low systemic bioavailability. However, curcumin can be encapsulated into liposomes to improve systemic bioavailability...
  7. ncbi request reprint Combinatorial nanoparticles for cancer diagnosis and therapy
    A Mukerjee
    Department of Molecular Biology and Immunology, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
    Curr Med Chem 19:3714-21. 2012
    ..In this review, we have classified these combinatorial targeted nanoparticles into inorganic, polymeric and liposome based nanosystems...
  8. ncbi request reprint Efficient nanoparticle mediated sustained RNA interference in human primary endothelial cells
    Anindita Mukerjee
    Department of Molecular Biology and Immunology, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Nanotechnology 22:445101. 2011
    ..This may serve as a potential adjuvant treatment option for diseases such as diabetic retinopathy, retinopathy of prematurity and age related macular degeneration besides various cancers...
  9. pmc Scale up, optimization and stability analysis of Curcumin C3 complex-loaded nanoparticles for cancer therapy
    Amalendu P Ranjan
    Department of Molecular Biology and Immunology and Institute for Cancer Research, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    J Nanobiotechnology 10:38. 2012
    ..This process is not only critical but also difficult as it involves various formulation parameters to be modulated all in the same process...
  10. doi request reprint Signal transducer and activator of transcription 6 (STAT6) is a novel interactor of annexin A2 in prostate cancer cells
    Susobhan Das
    Department of Molecular Biology and Immunology and Institute for Cancer Research, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
    Biochemistry 49:2216-26. 2010
    ..This report is the first to demonstrate the interaction of AnxA2 with STAT6 and suggests a possible mechanism by which AnxA2 contributes to the metastatic processes of prostate cancer...
  11. doi request reprint Alendronate coated poly-lactic-co-glycolic acid (PLGA) nanoparticles for active targeting of metastatic breast cancer
    Sanjay I Thamake
    Department of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Biomaterials 33:7164-73. 2012
    ..Our data show efficient attachment of Aln on the surface of nanoparticles which could be used as a drug carrier for preferential delivery of multiple therapeutic agents to bone microenvironment...
  12. doi request reprint Spectroscopic properties of curcumin: orientation of transition moments
    Anindita Mukerjee
    Department of Molecular Biology and Immunology, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, Texas 76107, USA
    J Phys Chem B 114:12679-84. 2010
    ....
  13. ncbi request reprint Formulation, characterization and evaluation of curcumin-loaded PLGA nanospheres for cancer therapy
    Anindita Mukerjee
    Department of Molecular Biology, Institute for Cancer Research, Graduate School of Biomedical Sciences, University of North Texas, Health Science Center, Fort Worth, TX, 76107, USA
    Anticancer Res 29:3867-75. 2009
    ..Our present work investigated the efficiency of encapsulation of curcumin in poly (lactic-coglycolic acid) (PLGA) nanospheres using solid/oil/water emulsion solvent evaporation method...
  14. ncbi request reprint Signal transducer and activator of transcription-6 (STAT6) is a constitutively expressed survival factor in human prostate cancer
    Susobhan Das
    Institute of Cancer Research and Department of Molecular Biology and Immunology, University of North Texas Health Science Center at Fort Worth, Texas 76107, USA
    Prostate 67:1550-64. 2007
    ..In this investigation, we examined STAT6 expression in clinical prostate cancer tissue specimen and determined its role in prostate cell proliferation and migration...
  15. ncbi request reprint Enhanced fluorescence of curcumin on plasmonic platforms
    Anindita Mukerjee
    Dept of Molecular Biology and Immunology and Institute of the Cancer Research, UNTHSC, Fort Worth, TX 76107, USA
    Curr Pharm Biotechnol 11:223-8. 2010
    ..We believe that the use of plasmonic platforms will improve detection, delivery and imaging of curcumin...
  16. pmc Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2
    Mallika Valapala
    Department of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
    J Biol Chem 286:30911-25. 2011
    ..The Ca(2+)-dependent exosomal transport constitutes a novel pathway of extracellular transport of AnxA2...
  17. pmc Fluorescence detection of MMP-9. I. MMP-9 selectively cleaves Lys-Gly-Pro-Arg-Ser-Leu-Ser-Gly-Lys peptide
    Rafal Fudala
    Center of Commercialization of Fluorescence Technologies, Department of Molecular Biology and Immunology, UNTHSC, Fort Worth, TX 76107, USA
    Curr Pharm Biotechnol 12:834-8. 2011
    ..The control MMP-2 enzyme does not cause any changes in either 5-FAM or Cy5 fluorescence. We believe that our observation will help in early detection of elevated MMP-9 levels under disease conditions...
  18. doi request reprint A sustained release formulation of chitosan modified PLCL:poloxamer blend nanoparticles loaded with optical agent for animal imaging
    Amalendu P Ranjan
    Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Nanotechnology 22:295104. 2011
    ..The successful formulation of such cationically modified nanoparticles for encapsulating optical agents may lead to a potential deep tissue imaging technique for tumor detection, diagnosis and therapy...
  19. pmc Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis
    Subhamoy Dasgupta
    Department of Biomedical Sciences and Institute for Cancer Research, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
    J Biol Chem 286:25935-46. 2011
    ..These findings demonstrate that prenylation is required for the function of the C17orf37 protein in cancer cells and imply that the post-translational modification may functionally regulate metastatic progression of disease...
  20. pmc A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events
    Mallika Valapala
    Department of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    J Cell Sci 124:1453-64. 2011
    ..These results suggest that AnxA2-mediated plasmin generation is an important event in angiogenesis and is inhibited by a specific competitive peptide that inhibits the binding of tPA to AnxA2...
  21. ncbi request reprint Polymeric nanoparticles for sustained down-regulation of annexin A2 inhibit prostate tumor growth
    Arthur R Braden
    Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    J Nanosci Nanotechnol 9:2856-65. 2009
    ..Our findings suggest that the use of sustained-release polymeric nanoparticles for down-regulation of annexin A2 expression may serve as an effective adjuvant treatment option for prostate cancer...
  22. ncbi request reprint Nanobiosensors: role in cancer detection and diagnosis
    Andrew Gdowski
    Department of Molecular Biology and Immunology, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA
    Adv Exp Med Biol 807:33-58. 2014
    ..Nanobiosensors will begin to transition into clinically validated tests as experimental and engineering techniques advance. This paper presents examples of some such nanobiosensors for cancer diagnosis and detection. ..
  23. pmc 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway
    Pankaj Chaudhary
    Department of Molecular Biology and Immunology and Institute for Cancer Research, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
    J Biol Chem 288:20532-46. 2013
    ..A novel role of GSTA4-4 in the maintenance of genomic integrity is also suggested. ..
  24. ncbi request reprint A comparative study of phytoestrogen action in mitigating apoptosis induced by oxidative stress
    Amber J Ondricek
    Cell Biology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    In Vivo 26:765-75. 2012
    ..Genistin reduced phosphorylation of p42 and p90RSK. Although these phytoestrogens are flavonoids and similar in structure, they exhibit different effects on cell signaling...
  25. ncbi request reprint Regulation of nucleo-cytoplasmic shuttling of human annexin A2: a proposed mechanism
    Jie Liu
    Institute for Cancer Research and Department of Molecular Biology and Immunology, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX 76107, USA
    Mol Cell Biochem 303:211-20. 2007
    ....
  26. doi request reprint A forensic path to RGC-5 cell line identification: lessons learned
    Raghu R Krishnamoorthy
    North Texas Eye Research Institute, Department of Cell Biology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA
    Invest Ophthalmol Vis Sci 54:5712-9. 2013
    ..The present study reviews some of the errors that were made in misidentifying the RGC-5 cell line and offers some insight as to how this may have happened, and ways one can avoid mischaracterization of a potentially important cell line...
  27. pmc Oncogenic activation in prostate cancer progression and metastasis: Molecular insights and future challenges
    Subhamoy Dasgupta
    Department of Molecular Biology and Immunology, and Institute for Cancer Research, University of North Texas Health Science Center, Fort Worth, TX, USA
    J Carcinog 11:4. 2012
    ..Recent advances provide novel insights into the molecular functions of these oncogenic activators, implicating potential therapeutic targeting opportunities for the treatment of prostate cancer...