Jyrki K Virtanen

Summary

Publications

  1. doi request reprint Associations of egg and cholesterol intakes with carotid intima-media thickness and risk of incident coronary artery disease according to apolipoprotein E phenotype in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
    Jyrki K Virtanen
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland and
    Am J Clin Nutr 103:895-901. 2016
  2. doi request reprint Serum long-chain omega-3 polyunsaturated Fatty acids and future blood pressure in an ageing population
    A N Nyantika
    Jyrki K Virtanen, University of Eastern Finland, Kuopio Campus, Institute of Public Health and Clinical Nutrition, PO Box 1627, 70211 Kuopio, Finland, 358 0 294454542 358 0 403552957 Fax 358 17 162936 E mail
    J Nutr Health Aging 19:498-503. 2015
  3. doi request reprint Dietary fatty acids and risk of coronary heart disease in men: the Kuopio Ischemic Heart Disease Risk Factor Study
    Jyrki K Virtanen
    From the Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Arterioscler Thromb Vasc Biol 34:2679-87. 2014
  4. doi request reprint Serum omega-3 polyunsaturated fatty acids and risk of incident type 2 diabetes in men: the Kuopio Ischemic Heart Disease Risk Factor study
    Jyrki K Virtanen
    Corresponding author Jyrki K Virtanen
    Diabetes Care 37:189-96. 2014
  5. pmc Serum long-chain n-3 polyunsaturated fatty acids, mercury, and risk of sudden cardiac death in men: a prospective population-based study
    Jyrki K Virtanen
    University of Eastern Finland, Institute of Public Health and Clinical Nutrition, Kuopio, Finland
    PLoS ONE 7:e41046. 2012
  6. doi request reprint Serum long-chain n-3 polyunsaturated fatty acids, methylmercury and blood pressure in an older population
    Jyrki K Virtanen
    University of Eastern Finland, Institute of Public Health and Clinical Nutrition, Kuopio, Finland
    Hypertens Res 35:1000-4. 2012
  7. pmc Dietary intake of polyunsaturated fatty acids and risk of hip fracture in men and women
    J K Virtanen
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, P O Box 1627, 70211, Kuopio, Finland
    Osteoporos Int 23:2615-24. 2012
  8. pmc Fish consumption, bone mineral density, and risk of hip fracture among older adults: the cardiovascular health study
    Jyrki K Virtanen
    University of Eastern Finland, Kuopio Campus, Institute of Public Health and Clinical Nutrition, Kuopio, Finland
    J Bone Miner Res 25:1972-9. 2010
  9. doi request reprint Association of serum 25-hydroxyvitamin D with the risk of death in a general older population in Finland
    Jyrki K Virtanen
    University of Eastern Finland, Kuopio Campus, Institute of Public Health and Clinical Nutrition, Finland
    Eur J Nutr 50:305-12. 2011
  10. ncbi request reprint Mercury, fish oils, and risk of acute coronary events and cardiovascular disease, coronary heart disease, and all-cause mortality in men in eastern Finland
    Jyrki K Virtanen
    Research Institute of Public Health, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
    Arterioscler Thromb Vasc Biol 25:228-33. 2005

Collaborators

Detail Information

Publications34

  1. doi request reprint Associations of egg and cholesterol intakes with carotid intima-media thickness and risk of incident coronary artery disease according to apolipoprotein E phenotype in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
    Jyrki K Virtanen
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland and
    Am J Clin Nutr 103:895-901. 2016
    ..There is little information on the association between cholesterol intake and the risk of coronary artery disease (CAD) among those with the ApoE4 phenotype...
  2. doi request reprint Serum long-chain omega-3 polyunsaturated Fatty acids and future blood pressure in an ageing population
    A N Nyantika
    Jyrki K Virtanen, University of Eastern Finland, Kuopio Campus, Institute of Public Health and Clinical Nutrition, PO Box 1627, 70211 Kuopio, Finland, 358 0 294454542 358 0 403552957 Fax 358 17 162936 E mail
    J Nutr Health Aging 19:498-503. 2015
    ..To investigate the associations of serum long-chain omega-3 polyunsaturated fatty acids (PUFA) and hair mercury with future blood pressure in an ageing population...
  3. doi request reprint Dietary fatty acids and risk of coronary heart disease in men: the Kuopio Ischemic Heart Disease Risk Factor Study
    Jyrki K Virtanen
    From the Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Arterioscler Thromb Vasc Biol 34:2679-87. 2014
    ..We investigated the associations of dietary fatty acids with the risk of CHD and carotid atherosclerosis in men with high SFA intake and high rates of CHD...
  4. doi request reprint Serum omega-3 polyunsaturated fatty acids and risk of incident type 2 diabetes in men: the Kuopio Ischemic Heart Disease Risk Factor study
    Jyrki K Virtanen
    Corresponding author Jyrki K Virtanen
    Diabetes Care 37:189-96. 2014
    ..CONCLUSIONS Serum long-chain omega-3 PUFA concentration, an objective biomarker for fish intake, was associated with long-term lower risk of type 2 diabetes. ..
  5. pmc Serum long-chain n-3 polyunsaturated fatty acids, mercury, and risk of sudden cardiac death in men: a prospective population-based study
    Jyrki K Virtanen
    University of Eastern Finland, Institute of Public Health and Clinical Nutrition, Kuopio, Finland
    PLoS ONE 7:e41046. 2012
    ..It is also a major source of methylmercury, which was associated with increased risk of CVD in this study population. Impact of interaction between long-chain n-3 PUFA and methylmercury on the SCD risk is unknown...
  6. doi request reprint Serum long-chain n-3 polyunsaturated fatty acids, methylmercury and blood pressure in an older population
    Jyrki K Virtanen
    University of Eastern Finland, Institute of Public Health and Clinical Nutrition, Kuopio, Finland
    Hypertens Res 35:1000-4. 2012
    ..These results suggest that higher serum long-chain n-3 PUFA concentration has a modest inverse association with blood pressure in older men and women...
  7. pmc Dietary intake of polyunsaturated fatty acids and risk of hip fracture in men and women
    J K Virtanen
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, P O Box 1627, 70211, Kuopio, Finland
    Osteoporos Int 23:2615-24. 2012
    ..We investigated this association in 75,878 women and 46,476 men and did not find a significant role for polyunsaturated fatty acid intake in the prevention of hip fractures...
  8. pmc Fish consumption, bone mineral density, and risk of hip fracture among older adults: the cardiovascular health study
    Jyrki K Virtanen
    University of Eastern Finland, Kuopio Campus, Institute of Public Health and Clinical Nutrition, Kuopio, Finland
    J Bone Miner Res 25:1972-9. 2010
    ..36 for EPA + DHA]. High LA intake did not modify these associations. In this large prospective cohort of older adults, fish consumption was associated with very small differences in BMD and had no association with hip fracture risk...
  9. doi request reprint Association of serum 25-hydroxyvitamin D with the risk of death in a general older population in Finland
    Jyrki K Virtanen
    University of Eastern Finland, Kuopio Campus, Institute of Public Health and Clinical Nutrition, Finland
    Eur J Nutr 50:305-12. 2011
    ....
  10. ncbi request reprint Mercury, fish oils, and risk of acute coronary events and cardiovascular disease, coronary heart disease, and all-cause mortality in men in eastern Finland
    Jyrki K Virtanen
    Research Institute of Public Health, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
    Arterioscler Thromb Vasc Biol 25:228-33. 2005
    ..We investigated the effects of high mercury content in hair on the risk of acute coronary events and cardiovascular and all-cause mortality in men from eastern Finland...
  11. ncbi request reprint Serum homocysteine, folate and risk of stroke: Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study
    Jyrki K Virtanen
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    Eur J Cardiovasc Prev Rehabil 12:369-75. 2005
    ..Homocysteine and folate have been suggested to have opposite effects on the risk of stroke, although the results are controversial...
  12. doi request reprint Intake of fruit, berries, and vegetables and risk of type 2 diabetes in Finnish men: the Kuopio Ischaemic Heart Disease Risk Factor Study
    Jaakko Mursu
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Am J Clin Nutr 99:328-33. 2014
    ..Although higher intakes of fruit, berries, and vegetables (FBV) have been associated with reduced risk of type 2 diabetes (T2D) in some observational studies, the evidence is limited and inconclusive...
  13. ncbi request reprint High dietary methionine intake increases the risk of acute coronary events in middle-aged men
    Jyrki K Virtanen
    Research Institute of Public Health, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
    Nutr Metab Cardiovasc Dis 16:113-20. 2006
    ..To date, the effects of dietary intake of methionine, the key amino acid in homocysteine metabolism, on CVD have not been studied. Our aim was to examine the effects of dietary methionine intake on the risk of acute coronary events...
  14. ncbi request reprint The effects of coffee consumption on lipid peroxidation and plasma total homocysteine concentrations: a clinical trial
    Jaakko Mursu
    Research Institute of Public Health, University of Kuopio, P O Box 1627, 70211 Kuopio, Finland
    Free Radic Biol Med 38:527-34. 2005
    ..In conclusion, the consumption of filtered coffee does not have any detectable effects on lipid peroxidation in healthy nonsmoking men. The effect of coffee consumption on tHcy concentrations needs further investigation...
  15. ncbi request reprint Polyphenol-rich phloem enhances the resistance of total serum lipids to oxidation in men
    Jaakko Mursu
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    J Agric Food Chem 53:3017-22. 2005
    ..in a dose-dependent manner. Our results suggest that polyphenols may inhibit lipid peroxidation in the hydrophilic fraction of serum...
  16. pmc Functional COMT Val158Met polymorphism, risk of acute coronary events and serum homocysteine: the Kuopio ischaemic heart disease risk factor study
    Sari Voutilainen
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    PLoS ONE 2:e181. 2007
    ..Many genetic factors play a role in folate-homocysteine metabolism, like functional polymorphism (Val108Met) in the Catechol-O-methyltransferase (COMT) gene...
  17. ncbi request reprint Mercury as a risk factor for cardiovascular diseases
    Jyrki K Virtanen
    Research Institute of Public Health, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
    J Nutr Biochem 18:75-85. 2007
    ..There are several plausible mechanisms to explain the association; these are discussed in this review. We also review the epidemiological studies that have investigated the association between mercury and CVD...
  18. pmc Relevance of vitamin D receptor target genes for monitoring the vitamin D responsiveness of primary human cells
    Maja Vukić
    School of Medicine, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland
    PLoS ONE 10:e0124339. 2015
    ..In conclusion, both long-term and short-term vitamin D3 supplementation studies allow monitoring the vitamin D responsiveness of human individuals and represent new types of human in vivo vitamin D3 investigations. ..
  19. doi request reprint Dissecting high from low responders in a vitamin D3 intervention study
    Noora Saksa
    School of Medicine, Institute of Biomedicine, University of Eastern Finland, P O Box 1627, FIN 70211 Kuopio, Finland
    J Steroid Biochem Mol Biol 148:275-82. 2015
    ..This article is part of a Special Issue entitled '17th Vitamin D Workshop' . ..
  20. doi request reprint Body iron stores and the risk of type 2 diabetes in middle-aged men
    Alex Aregbesola
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Yliopistonranta 1C, PO Box 1627, FI70211 Kuopio, Finland
    Eur J Endocrinol 169:247-53. 2013
    ..We investigated the risk of type 2 diabetes mellitus (T2DM) over a wide range of body iron stores...
  21. doi request reprint Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals
    Jussi Ryynänen
    School of Medicine, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland
    Mol Nutr Food Res 58:2036-45. 2014
    ..Vitamin D₃, its biologically most active metabolite 1α,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃), and the vitamin D receptor (VDR) are important for adipose tissue biology...
  22. ncbi request reprint Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans
    Jaakko Mursu
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    Free Radic Biol Med 37:1351-9. 2004
    ..Cocoa polyphenols may increase the concentration of HDL cholesterol, whereas chocolate fatty acids may modify the fatty acid composition of LDL and make it more resistant to oxidative damage...
  23. pmc Glucose Metabolism Effects of Vitamin D in Prediabetes: The VitDmet Randomized Placebo-Controlled Supplementation Study
    Tomi Pekka Tuomainen
    Unit of Public Health, The Institute of Public Health and Clinical Nutrition, University of Eastern Finland, P O Box 1627, 70211 Kuopio, Finland
    J Diabetes Res 2015:672653. 2015
    ..070). Vitamin D3 supplementation does not improve glucose metabolism in ageing subjects with prediabetes but may have modest anti-inflammatory effects...
  24. doi request reprint Serum long-chain n-3 polyunsaturated fatty acids and risk of hospital diagnosis of atrial fibrillation in men
    Jyrki K Virtanen
    Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, Kuopio, Finland
    Circulation 120:2315-21. 2009
    ..We tested this hypothesis by studying the association between the serum long-chain n-3 PUFAs eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid and risk of AF in men...
  25. doi request reprint Association of serum 25-hydroxyvitamin D with type 2 diabetes and markers of insulin resistance in a general older population in Finland
    Anne Riina Hurskainen
    The Institute of Public Health and Clinical Nutrition, University of Eastern Finland, PO Box 1627, 70211 Kuopio, Finland
    Diabetes Metab Res Rev 28:418-23. 2012
    ..Our aim was to study the associations between serum 25-hydroxyvitamin D [25(OH)D], a marker of vitamin D status, and glucose homeostasis and type 2 diabetes in a general population sample in Eastern Finland...
  26. doi request reprint Serum ferritin and glucose homeostasis: change in the association by glycaemic state
    Alex Aregbesola
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Yliopistonranta 1C, Kuopio, Finland
    Diabetes Metab Res Rev 31:507-14. 2015
    ....
  27. doi request reprint Serum 25-hydroxyvitamin D3 and the risk of pneumonia in an ageing general population
    Alex Aregbesola
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Yliopistonranta 1C, P O Box 1627, Kuopio, North Savo FI70211, Finland
    J Epidemiol Community Health 67:533-6. 2013
    ..We therefore investigated the effect of serum 25-hydroxyvitamin D₃ (25(OH)D₃) on the risk of incident hospitalised pneumonia in an ageing general population in eastern Finland...
  28. doi request reprint Serum polyunsaturated fatty acids are not associated with the risk of severe depression in middle-aged Finnish men: Kuopio Ischaemic Heart Disease Risk Factor (KIHD) study
    Anu Ruusunen
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, Kuopio, Finland
    Eur J Nutr 50:89-96. 2011
    ..The aim of this study is to investigate whether serum n - 3 polyunsaturated fatty acids (PUFAs) or n - 6 to n - 3 ratio is associated with risk of severe depression in middle-aged Finnish men...
  29. doi request reprint Egg consumption and risk of incident type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
    Jyrki K Virtanen
    From the Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Am J Clin Nutr 101:1088-96. 2015
    ..However, there are limited and conflicting data from prospective population studies on the association between egg consumption and risk of T2D...
  30. doi request reprint The association between serum 25-hydroxyvitamin D3 concentration and risk of disease death in men: modification by magnesium intake
    Jaakko Mursu
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, P O Box 1627, 70211, Kuopio, Finland
    Eur J Epidemiol 30:343-7. 2015
    ..63) in the higher magnesium intake median, P for interaction = 0.08. In this cohort of middle-aged and older men low serum 25(OH)D3 concentration was associated with increased risk of death mainly in those with lower magnesium intake...
  31. pmc Circulating omega-3 polyunsaturated fatty acids and subclinical brain abnormalities on MRI in older adults: the Cardiovascular Health Study
    Jyrki K Virtanen
    University of Eastern Finland, Institute of Public Health and Clinical Nutrition, Kuopio, Finland
    J Am Heart Assoc 2:e000305. 2013
    ..We investigated the association between plasma phospholipid omega-3 polyunsaturated fatty acids (PUFAs), objective biomarkers of exposure, and subclinical brain abnormalities on MRI...
  32. doi request reprint Primary vitamin D receptor target genes as biomarkers for the vitamin D3 status in the hematopoietic system
    Julia Wilfinger
    School of Medicine, Institute of Biomedicine, University of Eastern Finland, FIN 70211 Kuopio, Finland
    J Nutr Biochem 25:875-84. 2014
    ..In particular, NRIP1 exceeds the potential of the previously identified marker CD14 by more than 40% and seems to be a well-suited molecular marker for the vitamin D(3) status in the hematopoietic system...
  33. doi request reprint Serum zinc and risk of type 2 diabetes incidence in men: The Kuopio Ischaemic Heart Disease Risk Factor Study
    Teymoor Yary
    The University of Eastern Finland, Institute of Public Health and Clinical Nutrition, P O Box 1627, 70211 Kuopio, Finland
    J Trace Elem Med Biol 33:120-4. 2016
    ..However, the role of zinc in the etiology of T2D has been poorly investigated. This study was conducted to study the association of serum zinc on T2D risk in middle-aged and older Finnish men...
  34. ncbi request reprint Serum folate and homocysteine and the incidence of acute coronary events: the Kuopio Ischaemic Heart Disease Risk Factor Study
    Sari Voutilainen
    Research Institute of Public Health, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
    Am J Clin Nutr 80:317-23. 2004
    ....