- Gene Designer: a synthetic biology tool for constructing artificial DNA segments
DNA 2 0, Inc, 1430 O Brien Drive Suite E, Menlo Park, CA 94025, USA
BMC Bioinformatics 7:285. 2006
..Here we introduce a software tool that drastically facilitates the design of synthetic genes...
- Design parameters to control synthetic gene expression in Escherichia coli
DNA2 0, Menlo Park, CA, USA
PLoS ONE 4:e7002. 2009
..Protein-coding sequences are commonly re-designed to enhance expression, but there are no experimentally supported design principles...
- Designing genes for successful protein expression
DNA2 0, Inc, Suite A, Menlo Park, California, USA
Methods Enzymol 498:43-66. 2011
..Finally, we show how many of these methods can be accomplished using the synthetic biology software tool Gene Designer...
- Engineering genes for predictable protein expression
DNA2 0 Inc, 1140 O Brien Drive, Menlo Park, CA 94025, USA
Protein Expr Purif 83:37-46. 2012
..We here discuss how these new tools are being applied and how they circumvent the constraints of previous approaches, highlighting some of the surprising and promising results emerging from the developing field of gene engineering...
- In silico design of functional DNA constructs
DNA2 0, Inc, Menlo Park, CA, USA
Methods Mol Biol 852:197-213. 2012
..Together, the functions in Gene Designer provide a complete capability to design functional genetic constructs...
- You're one in a googol: optimizing genes for protein expression
DNA 2 0, Inc, 1430 O Brien Drive, Menlo Park, CA 94025, USA
J R Soc Interface 6:S467-76. 2009