Jeremy N Day

Summary

Affiliation: Ho Chi Minh City
Country: Vietnam

Publications

  1. doi request reprint Combination antifungal therapy for cryptococcal meningitis
    Jeremy N Day
    Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme Vietnam, Ho Chi Minh City, Vietnam
    N Engl J Med 368:1291-302. 2013
  2. pmc Intensified treatment with high dose rifampicin and levofloxacin compared to standard treatment for adult patients with tuberculous meningitis (TBM-IT): protocol for a randomized controlled trial
    Dorothee Heemskerk
    Hospital for Tropical Diseases Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme 190 Ben Ham Tu, District 5, Ho Chi Minh City, Vietnam
    Trials 12:25. 2011
  3. pmc Sample size requirements for separating out the effects of combination treatments: randomised controlled trials of combination therapy vs. standard treatment compared to factorial designs for patients with tuberculous meningitis
    Marcel Wolbers
    Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme and Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    Trials 12:26. 2011
  4. pmc Most cases of cryptococcal meningitis in HIV-uninfected patients in Vietnam are due to a distinct amplified fragment length polymorphism-defined cluster of Cryptococcus neoformans var. grubii VN1
    Jeremy N Day
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    J Clin Microbiol 49:658-64. 2011
  5. pmc A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam - high prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease
    Tran Th Chau
    Hospital for Tropical Diseases, Quan, Ho Chi Minh City, Vietnam
    BMC Infect Dis 10:199. 2010
  6. pmc Epidemiology, seasonality, and predictors of outcome of AIDS-associated Penicillium marneffei infection in Ho Chi Minh City, Viet Nam
    Thuy Le
    Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Viet Nam
    Clin Infect Dis 52:945-52. 2011
  7. doi request reprint The decline of typhoid and the rise of non-typhoid salmonellae and fungal infections in a changing HIV landscape: bloodstream infection trends over 15 years in southern Vietnam
    Tran Vu Thieu Nga
    The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    Trans R Soc Trop Med Hyg 106:26-34. 2012
  8. pmc AIDS-associated Penicillium marneffei infection of the central nervous system
    Thuy Le
    Wellcome Trust Major Overseas Programmes, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    Clin Infect Dis 51:1458-62. 2010
  9. doi request reprint AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic dilemma in resource‐limited settings
    Thuy Le
    Wellcome Trust Major Overseas Programmes, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    Clin Infect Dis 51:e65-8. 2010

Collaborators

Detail Information

Publications9

  1. doi request reprint Combination antifungal therapy for cryptococcal meningitis
    Jeremy N Day
    Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme Vietnam, Ho Chi Minh City, Vietnam
    N Engl J Med 368:1291-302. 2013
    ..We performed a randomized, controlled trial to determine whether combining flucytosine or high-dose fluconazole with high-dose amphotericin B improved survival at 14 and 70 days...
  2. pmc Intensified treatment with high dose rifampicin and levofloxacin compared to standard treatment for adult patients with tuberculous meningitis (TBM-IT): protocol for a randomized controlled trial
    Dorothee Heemskerk
    Hospital for Tropical Diseases Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme 190 Ben Ham Tu, District 5, Ho Chi Minh City, Vietnam
    Trials 12:25. 2011
    ....
  3. pmc Sample size requirements for separating out the effects of combination treatments: randomised controlled trials of combination therapy vs. standard treatment compared to factorial designs for patients with tuberculous meningitis
    Marcel Wolbers
    Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme and Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    Trials 12:26. 2011
    ..This can either be tested with a simple randomized trial of combination versus standard treatment or with a 2 x 2 factorial design...
  4. pmc Most cases of cryptococcal meningitis in HIV-uninfected patients in Vietnam are due to a distinct amplified fragment length polymorphism-defined cluster of Cryptococcus neoformans var. grubii VN1
    Jeremy N Day
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    J Clin Microbiol 49:658-64. 2011
    ..Two clusters of C. neoformans var. grubii VN1 are responsible for the majority of cases of cryptococcal meningitis in Vietnam. The distribution of these clusters differs according to the immune status of the host...
  5. pmc A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam - high prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease
    Tran Th Chau
    Hospital for Tropical Diseases, Quan, Ho Chi Minh City, Vietnam
    BMC Infect Dis 10:199. 2010
    ..We describe a cohort of HIV uninfected Vietnamese patients with cryptococcal meningitis in whom underlying disease is uncommon, and relate presenting features of patients and the characteristics of the infecting species to outcome...
  6. pmc Epidemiology, seasonality, and predictors of outcome of AIDS-associated Penicillium marneffei infection in Ho Chi Minh City, Viet Nam
    Thuy Le
    Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Viet Nam
    Clin Infect Dis 52:945-52. 2011
    ..Penicillium marneffei is an important human immunodeficiency virus (HIV)-associated opportunistic pathogen in Southeast Asia. The epidemiology and the predictors of penicilliosis outcome are poorly understood...
  7. doi request reprint The decline of typhoid and the rise of non-typhoid salmonellae and fungal infections in a changing HIV landscape: bloodstream infection trends over 15 years in southern Vietnam
    Tran Vu Thieu Nga
    The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    Trans R Soc Trop Med Hyg 106:26-34. 2012
    ..We propose such changes are related to increasing economic prosperity and HIV prevalence, and this pattern marks a substantial change in the epidemiology of invasive salmonellosis in Southeast Asia...
  8. pmc AIDS-associated Penicillium marneffei infection of the central nervous system
    Thuy Le
    Wellcome Trust Major Overseas Programmes, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    Clin Infect Dis 51:1458-62. 2010
    ....
  9. doi request reprint AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic dilemma in resource‐limited settings
    Thuy Le
    Wellcome Trust Major Overseas Programmes, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    Clin Infect Dis 51:e65-8. 2010
    ..Itraconazole poorly penetrates the central nervous system, whereas fluconazole has poor activity against P. marneffei. We prospectively report management of 1 patient and retrospectively review 7 coinfection cases from Vietnam...