René L Vidal

Summary

Publications

  1. ncbi Cellular and subcellular localization of Marlin-1 in the brain
    René L Vidal
    Fisiologia y Biofisica, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Independencia, Santiago, Chile
    BMC Neurosci 10:37. 2009
  2. ncbi RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons
    René L Vidal
    Program of Physiology and Biophysics, Institute of Biomedical Sciences, Universidad de Chile, Santiago, Chile
    Mol Cell Neurosci 51:1-11. 2012
  3. ncbi Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport
    René L Vidal
    Physiology and Biophysics, ICBM, Faculty of Medicine, Universidad de Chile Independencia 1027, Santiago, Chile
    Mol Cell Neurosci 35:501-12. 2007
  4. ncbi Dendritic assembly of heteromeric gamma-aminobutyric acid type B receptor subunits in hippocampal neurons
    Omar A Ramírez
    Physiology and Biophysics, Faculty of Medicine, Universidad de Chile, Santiago, Chile
    J Biol Chem 284:13077-85. 2009
  5. ncbi Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease
    René L Vidal
    Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile
    Autophagy 8:970-2. 2012
  6. ncbi Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
    René L Vidal
    Faculty of Medicine, Neuroscience Biomedical Institute, University of Chile, Santiago, Chile
    Hum Mol Genet 21:2245-62. 2012

Collaborators

Detail Information

Publications6

  1. ncbi Cellular and subcellular localization of Marlin-1 in the brain
    René L Vidal
    Fisiologia y Biofisica, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Independencia, Santiago, Chile
    BMC Neurosci 10:37. 2009
    ..Marlin-1 is expressed mainly in the central nervous system but little is known regarding its cellular and subcellular distribution in the brain...
  2. ncbi RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons
    René L Vidal
    Program of Physiology and Biophysics, Institute of Biomedical Sciences, Universidad de Chile, Santiago, Chile
    Mol Cell Neurosci 51:1-11. 2012
    ..Our results support the involvement of Marlin-1 in the acquisition of the complex architecture and migration of pyramidal neurons, two fundamental processes for the laminar layering of the cortex...
  3. ncbi Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport
    René L Vidal
    Physiology and Biophysics, ICBM, Faculty of Medicine, Universidad de Chile Independencia 1027, Santiago, Chile
    Mol Cell Neurosci 35:501-12. 2007
    ..Finally, we report that a kinesin-I mutant severely impairs receptor transport. We conclude that Marlin-1 and kinesin-1 link GABA(B)Rs to the tubulin cytoskeleton in neurons...
  4. ncbi Dendritic assembly of heteromeric gamma-aminobutyric acid type B receptor subunits in hippocampal neurons
    Omar A Ramírez
    Physiology and Biophysics, Faculty of Medicine, Universidad de Chile, Santiago, Chile
    J Biol Chem 284:13077-85. 2009
    ..Our results are consistent with a bulk flow of segregated subunits through the ER and rule out a post-Golgi vesicular transport of preassembled GABA(B)Rs...
  5. ncbi Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease
    René L Vidal
    Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile
    Autophagy 8:970-2. 2012
    ..These stress sensors control the expression of specialized transcription factors that modulate the upregulation of a variety of target genes involved in folding, protein quality control, autophagy and protein synthesis...
  6. ncbi Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
    René L Vidal
    Faculty of Medicine, Neuroscience Biomedical Institute, University of Chile, Santiago, Chile
    Hum Mol Genet 21:2245-62. 2012
    ..Our results provide strong evidence supporting an involvement of XBP1 in HD pathogenesis probably due to an ER stress-independent mechanism involving the control of FoxO1 and autophagy levels...