René L Vidal

Summary

Publications

  1. pmc Cellular and subcellular localization of Marlin-1 in the brain
    René L Vidal
    Fisiologia y Biofisica, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Independencia, Santiago, Chile
    BMC Neurosci 10:37. 2009
  2. doi request reprint RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons
    René L Vidal
    Program of Physiology and Biophysics, Institute of Biomedical Sciences, Universidad de Chile, Santiago, Chile
    Mol Cell Neurosci 51:1-11. 2012
  3. ncbi request reprint Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport
    René L Vidal
    Physiology and Biophysics, ICBM, Faculty of Medicine, Universidad de Chile Independencia 1027, Santiago, Chile
    Mol Cell Neurosci 35:501-12. 2007
  4. pmc Dendritic assembly of heteromeric gamma-aminobutyric acid type B receptor subunits in hippocampal neurons
    Omar A Ramírez
    Physiology and Biophysics, Faculty of Medicine, Universidad de Chile, Santiago, Chile
    J Biol Chem 284:13077-85. 2009
  5. pmc Unspliced XBP1 controls autophagy through FoxO1
    René L Vidal
    Neurounion Biomedical Foundation, University of Chile, Santiago, Chile
    Cell Res 23:463-4. 2013
  6. pmc Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease
    René L Vidal
    Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile
    Autophagy 8:970-2. 2012
  7. pmc Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
    René L Vidal
    Faculty of Medicine, Neuroscience Biomedical Institute, University of Chile, Santiago, Chile
    Hum Mol Genet 21:2245-62. 2012

Collaborators

Detail Information

Publications7

  1. pmc Cellular and subcellular localization of Marlin-1 in the brain
    René L Vidal
    Fisiologia y Biofisica, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Independencia, Santiago, Chile
    BMC Neurosci 10:37. 2009
    ..Marlin-1 is expressed mainly in the central nervous system but little is known regarding its cellular and subcellular distribution in the brain...
  2. doi request reprint RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons
    René L Vidal
    Program of Physiology and Biophysics, Institute of Biomedical Sciences, Universidad de Chile, Santiago, Chile
    Mol Cell Neurosci 51:1-11. 2012
    ..Our results support the involvement of Marlin-1 in the acquisition of the complex architecture and migration of pyramidal neurons, two fundamental processes for the laminar layering of the cortex...
  3. ncbi request reprint Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport
    René L Vidal
    Physiology and Biophysics, ICBM, Faculty of Medicine, Universidad de Chile Independencia 1027, Santiago, Chile
    Mol Cell Neurosci 35:501-12. 2007
    ..Finally, we report that a kinesin-I mutant severely impairs receptor transport. We conclude that Marlin-1 and kinesin-1 link GABA(B)Rs to the tubulin cytoskeleton in neurons...
  4. pmc Dendritic assembly of heteromeric gamma-aminobutyric acid type B receptor subunits in hippocampal neurons
    Omar A Ramírez
    Physiology and Biophysics, Faculty of Medicine, Universidad de Chile, Santiago, Chile
    J Biol Chem 284:13077-85. 2009
    ..Our results are consistent with a bulk flow of segregated subunits through the ER and rule out a post-Golgi vesicular transport of preassembled GABA(B)Rs...
  5. pmc Unspliced XBP1 controls autophagy through FoxO1
    René L Vidal
    Neurounion Biomedical Foundation, University of Chile, Santiago, Chile
    Cell Res 23:463-4. 2013
    ..In a paper recently published in Cell Research, Zhu and co-workers uncover a novel biological function of the unspliced form of the UPR transcription factor XBP1 in the modulation of autophagy through the control of FoxO1 turnover...
  6. pmc Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease
    René L Vidal
    Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile
    Autophagy 8:970-2. 2012
    ..These stress sensors control the expression of specialized transcription factors that modulate the upregulation of a variety of target genes involved in folding, protein quality control, autophagy and protein synthesis...
  7. pmc Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
    René L Vidal
    Faculty of Medicine, Neuroscience Biomedical Institute, University of Chile, Santiago, Chile
    Hum Mol Genet 21:2245-62. 2012
    ..Our results provide strong evidence supporting an involvement of XBP1 in HD pathogenesis probably due to an ER stress-independent mechanism involving the control of FoxO1 and autophagy levels...