Edward D Verrier

Summary

Publications

  1. ncbi request reprint Terminal complement blockade with pexelizumab during coronary artery bypass graft surgery requiring cardiopulmonary bypass: a randomized trial
    Edward D Verrier
    Division of Cardiothoracic Surgery, University of Washington School of Medicine, Seattle 98195 6310, USA
    JAMA 291:2319-27. 2004
  2. ncbi request reprint Alpha chemokines regulate direct lung ischemia-reperfusion injury
    Alexander S Farivar
    University of Washington Medical Center, Division of Cardiothoracic Surgery, Seattle, Washington 98195, USA
    J Heart Lung Transplant 23:585-91. 2004
  3. ncbi request reprint Early activation of the alveolar macrophage is critical to the development of lung ischemia-reperfusion injury
    Babu V Naidu
    Division of Cardiothoracic Surgery, Department of Surgery, University of Washington, Seattle 98195, USA
    J Thorac Cardiovasc Surg 126:200-7. 2003
  4. ncbi request reprint Crosstalk between thrombosis and inflammation in lung reperfusion injury
    Alexander S Farivar
    Division of Cardiothoracic Surgery, University of Washington Medical Center, Seattle, Washington 98195, USA
    Ann Thorac Surg 81:1061-7. 2006
  5. ncbi request reprint Toll-like receptor 4 mediates ischemia/reperfusion injury of the heart
    Albert J Chong
    Division of Cardiothoracic Surgery, Department of Surgery, The University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
    J Thorac Cardiovasc Surg 128:170-9. 2004
  6. ncbi request reprint Pexelizumab -- a C5 complement inhibitor for use in both acute myocardial infarction and cardiac surgery with cardiopulmonary bypass
    Ani J Fleisig
    Division of Cardiothoracic Surgery, University of Washington, 1959 NE Pacific Seattle, Washington, WA 98195, USA
    Expert Opin Biol Ther 5:833-9. 2005
  7. ncbi request reprint Myocardial infarction following coronary artery bypass graft surgery increases healthcare resource utilization
    John C Chen
    Division of Cardiothoracic Surgery, University of Hawaii School of Medicine, Honolulu, USA
    Crit Care Med 35:1296-301. 2007
  8. ncbi request reprint FR167653 reduces obliterative airway disease in rats
    Alexander S Farivar
    Department of Surgery, Division of Cardiothoracic Surgery, University of Washington Medical Center, 1959 NE Pacific Street, Seattle, WA 98195, USA
    J Heart Lung Transplant 23:985-92. 2004
  9. pmc Effect of cytokine hemoadsorption on brain death-induced ventricular dysfunction in a porcine model
    Krasimira M Mikhova
    Division of Cardiothoracic Surgery, University of Washington Medical Center, Seattle, Wash, USA
    J Thorac Cardiovasc Surg 145:215-23; discussion 223-4. 2013
  10. pmc Open-chest management after heart transplantation
    Hiroo Takayama
    Division of Cardiothoracic Surgery, University of Washington, Seattle, Washington 98195, USA
    Tex Heart Inst J 33:306-9. 2006

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Terminal complement blockade with pexelizumab during coronary artery bypass graft surgery requiring cardiopulmonary bypass: a randomized trial
    Edward D Verrier
    Division of Cardiothoracic Surgery, University of Washington School of Medicine, Seattle 98195 6310, USA
    JAMA 291:2319-27. 2004
    ..Inflammation and ischemia-reperfusion injury during coronary artery bypass graft (CABG) surgery requiring cardiopulmonary bypass are associated with postoperative myocardial infarction (MI) and mortality...
  2. ncbi request reprint Alpha chemokines regulate direct lung ischemia-reperfusion injury
    Alexander S Farivar
    University of Washington Medical Center, Division of Cardiothoracic Surgery, Seattle, Washington 98195, USA
    J Heart Lung Transplant 23:585-91. 2004
    ....
  3. ncbi request reprint Early activation of the alveolar macrophage is critical to the development of lung ischemia-reperfusion injury
    Babu V Naidu
    Division of Cardiothoracic Surgery, Department of Surgery, University of Washington, Seattle 98195, USA
    J Thorac Cardiovasc Surg 126:200-7. 2003
    ..The present studies were undertaken to determine whether the alveolar macrophage plays a similarly important role in lung ischemia-reperfusion injury...
  4. ncbi request reprint Crosstalk between thrombosis and inflammation in lung reperfusion injury
    Alexander S Farivar
    Division of Cardiothoracic Surgery, University of Washington Medical Center, Seattle, Washington 98195, USA
    Ann Thorac Surg 81:1061-7. 2006
    ..We used hirudin, a potent, specific direct thrombin inhibitor, to define the role of thrombin in lung ischemia-reperfusion injury...
  5. ncbi request reprint Toll-like receptor 4 mediates ischemia/reperfusion injury of the heart
    Albert J Chong
    Division of Cardiothoracic Surgery, Department of Surgery, The University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
    J Thorac Cardiovasc Surg 128:170-9. 2004
    ..We used C3H/HeJ mice, which express a nonfunctional toll-like receptor 4, to assess the pertinence of this receptor to tissue injury after reperfusion of ischemic myocardium...
  6. ncbi request reprint Pexelizumab -- a C5 complement inhibitor for use in both acute myocardial infarction and cardiac surgery with cardiopulmonary bypass
    Ani J Fleisig
    Division of Cardiothoracic Surgery, University of Washington, 1959 NE Pacific Seattle, Washington, WA 98195, USA
    Expert Opin Biol Ther 5:833-9. 2005
    ..Thus, pexelizumab represents a promising therapeutic option with sustained benefit both in AMI and during CABG with CPB...
  7. ncbi request reprint Myocardial infarction following coronary artery bypass graft surgery increases healthcare resource utilization
    John C Chen
    Division of Cardiothoracic Surgery, University of Hawaii School of Medicine, Honolulu, USA
    Crit Care Med 35:1296-301. 2007
    ..To assess the health economic impact of perioperative myocardial infarction in a cohort of patients undergoing coronary artery bypass graft surgery...
  8. ncbi request reprint FR167653 reduces obliterative airway disease in rats
    Alexander S Farivar
    Department of Surgery, Division of Cardiothoracic Surgery, University of Washington Medical Center, 1959 NE Pacific Street, Seattle, WA 98195, USA
    J Heart Lung Transplant 23:985-92. 2004
    ..These studies assessed whether specific inhibition of p38 with FR167653 (FR) protects against the development of OB in rat tracheal allografts...
  9. pmc Effect of cytokine hemoadsorption on brain death-induced ventricular dysfunction in a porcine model
    Krasimira M Mikhova
    Division of Cardiothoracic Surgery, University of Washington Medical Center, Seattle, Wash, USA
    J Thorac Cardiovasc Surg 145:215-23; discussion 223-4. 2013
    ..In an effort to expand the cardiac donor pool, we tested the hypothesis that hemoadsorption of cytokines attenuates brain death-induced ventricular dysfunction...
  10. pmc Open-chest management after heart transplantation
    Hiroo Takayama
    Division of Cardiothoracic Surgery, University of Washington, Seattle, Washington 98195, USA
    Tex Heart Inst J 33:306-9. 2006
    ..No patient had sternal wound infection or impaired wound healing during the follow-up period. We conclude that, when required, open-chest management is an effective and safe measure for hemodynamically unstable heart transplant patients...
  11. ncbi request reprint Activation of the endothelium in cardiac allografts
    Edward D Verrier
    Division of Cardiothoracic Surgery, Department of Surgery, The University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
    J Heart Lung Transplant 23:S229-33. 2004
  12. ncbi request reprint Tissue factor and thrombin mediate myocardial ischemia-reperfusion injury
    Albert J Chong
    Division of Cardiothoracic Surgery, The University of Washington, Seattle, Washington 98104, USA
    Ann Thorac Surg 75:S649-55. 2003
    ..However, defibrinogenating rabbits with ancrod had no effect on infarct size, suggesting a requirement of thrombin generation but not fibrin deposition in myocardial I/R injury...
  13. ncbi request reprint Endogenous interleukin-4 and interleukin-10 regulate experimental lung ischemia reperfusion injury
    Alexander S Farivar
    Division of Cardiothoracic Surgery, University of Washington Medical Center, Seattle, Washington 98195, USA
    Ann Thorac Surg 76:253-9. 2003
    ..These studies were undertaken to investigate the role of two regulatory cytokines, interleukin-4 (IL-4) and IL-10, in an in vivo model of LIRI...
  14. ncbi request reprint Limitation of thrombin generation, platelet activation, and inflammation by elimination of cardiotomy suction in patients undergoing coronary artery bypass grafting treated with heparin-bonded circuits
    Gabriel S Aldea
    Division of Cardiothoracic Surgery, Department of Surgery, University of Washington School of Medicine, Seattle, WA 98195 3166, USA
    J Thorac Cardiovasc Surg 123:742-55. 2002
    ..A prospective, randomized study was undertaken to evaluate the specific effects of cardiotomy suction...
  15. ncbi request reprint Pexelizumab reduces death and myocardial infarction in higher risk cardiac surgical patients
    Axel Haverich
    Hannover Medical School, Hannover, Germany
    Ann Thorac Surg 82:486-92. 2006
    ....
  16. ncbi request reprint Effect of pexelizumab on mortality in patients with acute myocardial infarction or undergoing coronary artery bypass surgery: a systematic overview
    Kenneth W Mahaffey
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Am Heart J 152:291-6. 2006
    ....
  17. ncbi request reprint A short wholly inside-out reversed vascular graft facilitating difficult aortic anastomosis
    Shih Rong Hsieh
    Division of Cardiovascular Surgery, Department of Surgery, Taichung Veterans General Hospital, National Yang Ming University, School of Medicine, Taichung, Taiwan, China
    Ann Thorac Surg 80:1534-6. 2005
    ..We present a new technique derived from a modified elephant trunk technique to simplify some laborious situations...
  18. ncbi request reprint Inhibition of Toll-like receptor 4 with eritoran attenuates myocardial ischemia-reperfusion injury
    Akira Shimamoto
    Department of Thoracic and Cardiovascular Surgery, Mie University Graduate School of Medicine, 2 174, Edobashi, Tsu, Mie 514 8507, Japan
    Circulation 114:I270-4. 2006
    ..To investigate the ligand-activating TLR4 during MI/R injury, we evaluated the effect of eritoran, a specific TLR4 antagonist, on MI/R injury, with the goal of defining better therapeutic options for MI/R injury...
  19. ncbi request reprint Unique considerations for the spinal cord injured patient undergoing cardiac surgery utilizing cardiopulmonary bypass
    Arnold M Benak
    Central Maine Heart and Vascular Institute, Lewiston, Maine 04240, USA
    J Extra Corpor Technol 35:230-7. 2003
    ..Numerous triggering mechanisms may lead to a variety of clinical complications. Consideration of a response/ treatment management plan for potential problems must be exercised by the surgical team...
  20. ncbi request reprint HSP70.1 and -70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts
    Craig R Hampton
    Department of Surgery, University of Washington, 1959 N E Pacific Street, Box 356410, Seattle, WA 98195, USA
    Am J Physiol Heart Circ Physiol 285:H866-74. 2003
    ..1/3(-/-) mice. We conclude that inducible HSP70.1 and HSP70.3 are required for late-phase protection against infarction following IP in mice...
  21. pmc Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy
    Rafal Pawlinski
    The Scripps Research Institute, Department of Immunology, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
    Circulation 116:2298-306. 2007
    ..The purpose of the present study was to investigate the role of PAR-1 in infarction, cardiac remodeling, and hypertrophy after I/R injury. In addition, we analyzed the effect of overexpression of PAR-1 on cardiomyocytes...
  22. ncbi request reprint FR167653 diminishes infarct size in a murine model of myocardial ischemia-reperfusion injury
    Masaki Yada
    Department of Thoracic and Cardiovascular Surgery, Mie University School of Medicine, Tsu, Japan
    J Thorac Cardiovasc Surg 128:588-94. 2004
    ..We examined the effect of a highly specific inhibitor of p38 mitogen-activated protein kinase, FR167653, in an experimental model of regional myocardial ischemia-reperfusion...