A novel chromosomal translocation and heteromorphism in a female with recurrent pregnancy loss--a case studyVenkateshwari Ananthapur
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, 500 016, India
J Assist Reprod Genet 29:651-6. 2012
..To evaluate the clinical, biochemical and cytogenetic analyses of a couple with reproductive failure...
Clinical and behavioural profile of a rare variant of Klinefelter syndrome-48, XXXYA Venkateshwari
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India
Indian J Pediatr 77:447-9. 2010
..The presence of an extra X chromosome/s in these individuals has a great impact on the physical and cognitive functions, which could be attributed to gene dosage effects and genes involved in neurogenic development...
De novo chromosomal translocation t(3;5)(q13;q35) in an infertile manA Venkateshwari
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India
Andrologia 43:428-30. 2011
..Cytogenetic analysis of the male partner showed a de novo chromosomal translocation t(3;5)(q13;q35) which could be involved in the meiotic errors resulting in reproductive failure...
Helicobacter pylori infection in relation to gastric cancer progressionA Venkateshwari
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500 016, India
Indian J Cancer 48:94-8. 2011
..In this review, we discuss the various virulence factors expressed by this bacterium and their interaction with the host factors, to influence pathogenesis...
Mosaic triple X syndrome in a female with primary amenorrheaA Venkateshwari
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, India
Indian J Hum Genet 18:246-9. 2012
..It is a result of absence of an X chromosome or the presence of a structurally abnormal X chromosome. Its most consistent clinical features are short stature and ovarian failure...
Role of matrix metalloproteinase 3 gene promoter polymorphism in chronic pancreatitisK Sri Manjari
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500 016, India
Indian J Gastroenterol 30:217-20. 2011
..To study the role of 5A/6A polymorphism of matrix metalloproteinase (MMP-3) and their levels in the pathogenesis of chronic pancreatitis (CP)...
Heterozygosity for TGF β1 -509C/T Polymorphism is associated with risk for breast cancer in South Indian populationCingeetham Vinod
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, 500016, India
Tumour Biol 34:99-105. 2013
..CT: OR 2.315, 95 % CI 1.143-4.688) and a border line significance with postmenopausal women (CT vs. CC: χ (2) = 3.128, P = 0.07, OR 2.095, 95 % CI 0.991-4.428)...
Plasma TGF-β1, MMP-1 and MMP-3 Levels in Chronic PancreatitisK Sri Manjari
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet Hyderabad, 500 016 India
Indian J Clin Biochem 27:152-6. 2012
..Thus, the present study highlights the role of fibrogenic cytokine marker TGF-β1 and matrix metalloproteinases in the pathogenesis of CP...
Matrix metalloproteinase-9, transforming growth factor-β1, and tumor necrosis factor-α plasma levels in chronic pancreatitisK Sri Manjari
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, 500 016, India
Indian J Gastroenterol 32:103-7. 2013
..The aim of the study was to investigate the plasma levels of matrix metalloproteinase-9 (MMP-9), transforming growth factor-β 1 (TGF-β1), and tumor necrosis factor-α (TNF-α) in chronic pancreatitis (CP)...
Role of transforming growth factor-β1 -509 C/T promoter polymorphism in gastric cancer in south Indian populationAmar Chand Bhayal
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, 500 016, India
Tumour Biol 32:1049-53. 2011
..379 in gastric cancer patients and 0.73 and 0.27 in control subjects, respectively. Our study imply that T allele of TGF-β1 -509 C/T genotypes may be a risk factor of genetic susceptibility to gastric cancer in south Indian population...