Ganesan Venkatasubramanian

Summary

Publications

  1. pmc Chlorpromazine induced cataract in a young patient with schizophrenia
    Anjith Divakaran
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Indian J Psychol Med 32:69-70. 2010
  2. pmc Neuroanatomical, neurochemical, and neurodevelopmental basis of obsessive-compulsive symptoms in schizophrenia
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychol Med 31:3-10. 2009
  3. pmc Entorhinal Cortex Volume in Antipsychotic-naïve Schizophrenia
    Sam P Jose
    Department of Psychiatry, The Schizophrenia Clinic, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychol Med 34:164-9. 2012
  4. pmc Biological investigations in Indian psychiatry
    Rishikesh V Behere
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Indian J Psychiatry 52:S136-8. 2010
  5. pmc A Longitudinal Study of Relation between Side-effects and Clinical Improvement in Schizophrenia: Is There a Neuro-metabolic Threshold for Second Generation Antipsychotics?
    Ganesan Venkatasubramanian
    The Metabolic Clinic in Psychiatry, Department of Psychiatry Translational Psychiatry Laboratory, Cognitive Neurobiology Division, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, India
    Clin Psychopharmacol Neurosci 11:24-7. 2013
  6. pmc Neuroanatomical correlates of psychopathology in antipsychotic-naïve schizophrenia
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Indian J Psychiatry 52:28-36. 2010
  7. pmc Expressed emotion in schizophrenia: an overview
    Anekal C Amaresha
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychol Med 34:12-20. 2012
  8. doi request reprint Comprehensive evaluation of cortical structure abnormalities in drug-naïve, adult patients with obsessive-compulsive disorder: a surface-based morphometry study
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560029, India
    J Psychiatr Res 46:1161-8. 2012
  9. doi request reprint Digit ratio (2D:4D) asymmetry and Schneiderian first rank symptoms: implications for cerebral lateralisation theories of schizophrenia
    Ganesan Venkatasubramanian
    Metabolic Clinic in Psychiatry, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560029, Karnataka, India
    Laterality 16:499-512. 2011
  10. ncbi request reprint Corpus callosum deficits in antipsychotic-naïve schizophrenia: evidence for neurodevelopmental pathogenesis
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Psychiatry Res 182:141-5. 2010

Collaborators

  • Rishikesh V Behere
  • Shivarama Varambally
  • Dhanya Raveendranathan
  • Matcheri S Keshavan
  • Seetharamaiah Chittiprol
  • B N Gangadhar
  • Y C Janardhan Reddy
  • Mukund G Rao
  • Vivek Benegal
  • Biju Viswanath
  • Nithin Krishna
  • Latha Velayudhan
  • Arindam Maitra
  • Dara M Cannon
  • David Mataix-Cols
  • Peruvumba Narayan Jayakumar
  • Naren P Rao
  • Janardhanan C Narayanaswamy
  • Sunil V Kalmady
  • Venkataram Shivakumar
  • Rashmi Arasappa
  • Naveen Jayaram
  • Anjith Divakaran
  • Vijay Danivas
  • Hema Nawani
  • Anushree Bose
  • Aditi Subramaniam
  • Sunil Vasu Kalmady
  • Sri Mahavir Agarwal
  • Anekal C Amaresha
  • Sunil Kalmady
  • Eesha Sharma
  • Nalini N Reddy
  • Gayatri Saraf
  • Gopalkumar Rakesh
  • Monojit Debnath
  • Dania Jose
  • Sam P Jose
  • Harve Shanmugam Virupaksha
  • Vaskar Chakraborty
  • Rajan Nishanth Jayarajan
  • Bangalore G Kalyani
  • Gaurav Goel
  • Rakhee Krishna
  • Naren Rao
  • Sugnyani Devi
  • Karthik Duraiswamy
  • Jagadisha Thirthalli
  • Naren Prahlada Rao
  • Kesavan Muralidharan
  • Dania Alphonse Jose
  • S Gautham
  • Harleen Chhabra
  • Vasanthapuram Ravi
  • Dania A Jose
  • Y C Janardhana Reddy
  • Aniruddh Narasimha
  • Anish V Cherian
  • Vishnurajan Rajendran
  • Vishal Kasal
  • Kandavel Thennarasu
  • Narayan R Mutalik
  • Suresh B Math
  • Channapatna R Chandrashekar
  • Y C Janardhan Reddy
  • Mandapatti K Vasudev
  • Vidya Narayan
  • Shoba Srinath
  • Mandapati K Vasudev
  • Cilna Mariam George
  • Mohammed Faruq
  • Meera Purushottam
  • Keshav J Kumar
  • Pramod Kumar Pal
  • Vinayak Korpade
  • Thennarasu Kandavel
  • Saumya Udupa
  • Hariprasad Rao
  • Sanjeev Jain
  • S Sanmuganathan
  • Mitali Mukherji
  • Shivashankar Ravishankar
  • Jitender Saini
  • Abish Antony
  • Kengeri V Kishore Kumar
  • Magadi N Naveen
  • Udupi Arunachala
  • Basappa K Venkatesh
  • Nalini Narayana Reddy
  • Pradeep Palaniyappan

Detail Information

Publications84

  1. pmc Chlorpromazine induced cataract in a young patient with schizophrenia
    Anjith Divakaran
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Indian J Psychol Med 32:69-70. 2010
    ..We report a patient who developed cataract possibly due to chlorpromazine and reviewed the relevant literature...
  2. pmc Neuroanatomical, neurochemical, and neurodevelopmental basis of obsessive-compulsive symptoms in schizophrenia
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychol Med 31:3-10. 2009
    ..Dopamine may be responsible for the beneficial role of antipsychotics in the treatment of OCD. In summary, we propose that glutamate, serotonin, and dopamine abnormalities may be the probable basis for OCSS...
  3. pmc Entorhinal Cortex Volume in Antipsychotic-naïve Schizophrenia
    Sam P Jose
    Department of Psychiatry, The Schizophrenia Clinic, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychol Med 34:164-9. 2012
    ..Several studies have looked at cytoarchitectural and morphometric changes in the ERC, but results have been inconsistent possibly due to the potential confounding effects of antipsychotic treatment...
  4. pmc Biological investigations in Indian psychiatry
    Rishikesh V Behere
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Indian J Psychiatry 52:S136-8. 2010
    ..In this selective overview we summarize findings of various EEG, neuro-imaging and blood related studies that have been reported in the Indian Journal of Psychiatry...
  5. pmc A Longitudinal Study of Relation between Side-effects and Clinical Improvement in Schizophrenia: Is There a Neuro-metabolic Threshold for Second Generation Antipsychotics?
    Ganesan Venkatasubramanian
    The Metabolic Clinic in Psychiatry, Department of Psychiatry Translational Psychiatry Laboratory, Cognitive Neurobiology Division, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, India
    Clin Psychopharmacol Neurosci 11:24-7. 2013
    ..This prospective study on antipsychotic-naïve schizophrenia patients, for the first-time, examined concurrently the relationship between clinical improvement and these side-effects NIES and Neuroleptic Induced Metabolic Side-effects...
  6. pmc Neuroanatomical correlates of psychopathology in antipsychotic-naïve schizophrenia
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Indian J Psychiatry 52:28-36. 2010
    ..None used automated image analysis to examine gray matter volume correlates of psychopathology in antipsychotic-naïve schizophrenia patients...
  7. pmc Expressed emotion in schizophrenia: an overview
    Anekal C Amaresha
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychol Med 34:12-20. 2012
    ..Hence, it is important that the future studies should focus on both protective and vulnerable factors within the construct of EE in schizophrenia to facilitate comprehensive care...
  8. doi request reprint Comprehensive evaluation of cortical structure abnormalities in drug-naïve, adult patients with obsessive-compulsive disorder: a surface-based morphometry study
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560029, India
    J Psychiatr Res 46:1161-8. 2012
    ....
  9. doi request reprint Digit ratio (2D:4D) asymmetry and Schneiderian first rank symptoms: implications for cerebral lateralisation theories of schizophrenia
    Ganesan Venkatasubramanian
    Metabolic Clinic in Psychiatry, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560029, Karnataka, India
    Laterality 16:499-512. 2011
    ..Since 2D:4D is linked with limbic asymmetry, our study findings offer further support to the cerebral lateralisation theories of schizophrenia...
  10. ncbi request reprint Corpus callosum deficits in antipsychotic-naïve schizophrenia: evidence for neurodevelopmental pathogenesis
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Psychiatry Res 182:141-5. 2010
    ..Together, these findings suggest neurodevelopmentally mediated hypoconnectivity in schizophrenia...
  11. doi request reprint Inverse relationship between serum high density lipoprotein and negative syndrome in antipsychotic-naive schizophrenia
    Ganesan Venkatasubramanian
    The Metabolic Clinic in Psychiatry, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Clin Chem Lab Med 48:95-8. 2010
    ..The objective of this study was to examine the correlation between symptom scores and serum HDL in antipsychotic-naive schizophrenia patients...
  12. doi request reprint Schneiderian first rank symptoms and inferior parietal lobule cortical thickness in antipsychotic-naïve schizophrenia
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560029, India
    Prog Neuropsychopharmacol Biol Psychiatry 35:40-6. 2011
    ..Deficient cortical thickness involving IPL in FRS(+) schizophrenia patients adds further support to the role of internal monitoring system in the pathogenesis of FRS in schizophrenia...
  13. ncbi request reprint A longitudinal study on the impact of antipsychotic treatment on serum leptin in schizophrenia
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Clin Neuropharmacol 33:288-92. 2010
    ..The study objective was to explore the biological basis for link between antipsychotic-induced weight gain and therapeutic response in schizophrenia by examining longitudinal changes in serum leptin level after antipsychotic treatment...
  14. ncbi request reprint Effect of antipsychotic treatment on Insulin-like Growth Factor-1 and cortisol in schizophrenia: a longitudinal study
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560029, India
    Schizophr Res 119:131-7. 2010
    ..These observations suggest a possible link between HPA axis abnormalities and IGF-1 deficits in the neurodevelopmental pathogenesis of schizophrenia...
  15. doi request reprint High energy phosphate abnormalities normalize after antipsychotic treatment in schizophrenia: a longitudinal 31P MRS study of basal ganglia
    Peruvumba N Jayakumar
    Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Bangalore, India
    Psychiatry Res 181:237-40. 2010
    ..Findings support the hypothesis that reduction of energy demand or induction of decreased energy-demanding processes might underlie the mechanism of action of antipsychotics in schizophrenia...
  16. ncbi request reprint First rank symptoms & facial emotion recognition deficits in antipsychotic naïve schizophrenia: Implications for social threat perception model
    Rishikesh V Behere
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Prog Neuropsychopharmacol Biol Psychiatry 35:1653-8. 2011
    ..There is a differential pattern of impairment in FERD, which supports the role of heightened threat perception in the evolution of psychopathology in schizophrenia patients...
  17. doi request reprint Effect of risperidone on emotion recognition deficits in antipsychotic-naïve schizophrenia: a short-term follow-up study
    Rishikesh V Behere
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Schizophr Res 113:72-6. 2009
    ..Facial emotion recognition deficits [FERD] have been consistently demonstrated in treated schizophrenia patients. FERD in treatment-naïve patients and the effect of antipsychotics are yet to be explored...
  18. ncbi request reprint Insulin and insulin-like growth factor-1 abnormalities in antipsychotic-naive schizophrenia
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neuro Sciences, Bangalore 560029, Karnataka, India
    Am J Psychiatry 164:1557-60. 2007
    ..The purpose of this study was to examine the evidence for the insulin-like growth factor-1 (IGF-1) deficiency hypothesis in the pathogenesis of schizophrenia...
  19. doi request reprint Beta2-microglobulin abnormalities in antipsychotic-naïve schizophrenia: evidence for immune pathogenesis
    Seetharamaiah Chittiprol
    Department of Neurochemistry, National Institute of Mental Health and Neurosciences, Bangalore 560029, India
    Brain Behav Immun 23:189-92. 2009
    ..32; p=0.035). These novel observations suggest that beta2M abnormalities might have a potential association with the pathogenesis of schizophrenia...
  20. doi request reprint Oxidative stress and neopterin abnormalities in schizophrenia: a longitudinal study
    Seetharamaiah Chittiprol
    Department of Neurochemistry, National Institute of Mental Health and Neurosciences, Bangalore 560029, India
    J Psychiatr Res 44:310-3. 2010
    ..Our study observations support increased oxidative stress in schizophrenia that improves with antipsychotic treatment...
  21. doi request reprint Late-onset clozapine-induced agranulocytosis in a patient with comorbid multiple sclerosis
    Dhanya Raveendranathan
    Department of Psychiatry, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore 560029, India Electronic address
    Gen Hosp Psychiatry 35:574.e5-6. 2013
    ....
  22. doi request reprint Neural basis of tDCS effects on auditory verbal hallucinations in schizophrenia: a case report evidence for cortical neuroplasticity modulation
    Hema Nawani
    From the Schizophrenia Clinic, Department of Psychiatry and Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 30:e2-4. 2014
    ....
  23. ncbi request reprint Insight facilitation with add-on tDCS in schizophrenia
    Anushree Bose
    The Schizophrenia Clinic, Department of Psychiatry and Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bangalore, India
    Schizophr Res 156:63-5. 2014
    ..Improvement in insight correlated significantly with improvement in severity of auditory hallucinations. These findings suggest improvement of insight with add-on tDCS in schizophrenia with persistent auditory hallucinations. ..
  24. doi request reprint Physical deformity as sequela of chronic catatonia and response to electroconvulsive therapy: a case report
    Sugnyani Devi
    Department of Psychiatry, Kasturba Medical College, Manipal, India
    J ECT 27:e49-50. 2011
    ..Early interventions in the form of electroconvulsive therapy and physical rehabilitation can be useful in reversing such potentially disabling complications...
  25. ncbi request reprint Developmental reflexes and 31P Magnetic Resonance Spectroscopy of basal ganglia in antipsychotic-naive schizophrenia
    Bangalore N Gangadhar
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore 560029, India
    Prog Neuropsychopharmacol Biol Psychiatry 30:910-3. 2006
    ..These patients had younger age-at-onset of psychosis. Together, this suggests neurodevelopmental etiopathogenesis in schizophrenia...
  26. doi request reprint Neuroanatomical correlates of neurological soft signs in antipsychotic-naive schizophrenia
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 5600 29, India
    Psychiatry Res 164:215-22. 2008
    ..Prefrontal and temporal cortices, putamen and cerebellum had significant volume deficits in patients. Cortical and cerebellar correlates of the sub-score MSS support the concept of "cognitive dysmetria" in schizophrenia...
  27. ncbi request reprint Clinical correlates of parametric digit-symbol substitution test in schizophrenia
    Anekal C Amaresha
    Department of Psychiatry, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, India Translational Psychiatry Laboratory, Cognitive Neurobiology Division, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bangalore, India
    Asian J Psychiatr 10:45-50. 2014
    ..Furthermore, pDSST deficits demonstrated a significant association with the psychopathology, especially with the various negative symptoms and bizarre behaviour. ..
  28. doi request reprint Piracetam treatment in patients with cognitive impairment
    Mukund G Rao
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560029, India
    Gen Hosp Psychiatry 35:451.e5-6. 2013
    ..This report highlights the need for caution in the use of piracetam, especially in those with past or family history of psychiatric illness. ..
  29. ncbi request reprint Rimonabant-induced catatonia in schizophrenia: A case report
    Nalini N Reddy
    The Metabolic Clinic in Psychiatry, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore 560029, Karnataka, India
    Obes Res Clin Pract 3:237-9. 2009
    ..In this first time report, we describe a patient with schizophrenia developing catatonia possibly due to rimonabant.: ..
  30. doi request reprint Revisiting Geschwind's hypothesis on brain lateralisation: a functional MRI study of digit ratio (2D:4D) and sex interaction effects on spatial working memory
    Sunil Vasu Kalmady
    Department of Psychiatry and Translational Psychiatry Laboratory, National Institute of Mental Health and Neurosciences, Bangalore, India
    Laterality 18:625-40. 2013
    ..Given the pre-existing background data supporting digit ratio measures as putative indicator of prenatal sex hormonal milieu, our study findings add support to the Geschwind-Behan-Galaburda (GBG) hypothesis. ..
  31. doi request reprint Vitamin B₁₂ levels and psychiatric symptomatology: a case series
    Naveen Jayaram
    Dept of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    J Neuropsychiatry Clin Neurosci 25:150-2. 2013
    ..A review of 19 patients (14 vegetarians) with demonstrable vitamin B₁₂ deficiency showed varied psychiatric symptomatology, with the majority not having significant hematological or neurological manifestations...
  32. doi request reprint Successful use of maintenance electroconvulsive therapy in the treatment of clozapine-associated obsessive-compulsive symptoms in schizophrenia: a case report
    Naren P Rao
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 27:e37-8. 2011
    ..We report, for the first time, the use of maintenance electroconvulsive therapy, in clozapine-associated OC symptoms, in a patient with schizophrenia...
  33. doi request reprint Relationship between corpus callosum abnormalities and schneiderian first-rank symptoms in antipsychotic-naive schizophrenia patients
    Naren P Rao
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560029, India
    J Neuropsychiatry Clin Neurosci 23:155-62. 2011
    ..A novel finding of the study is that only those without FRS differed from control subjects, but not those with FRS. Study findings support a neuro-developmental hypothesis and possible connectivity abnormalities in symptom-genesis...
  34. pmc Inferior parietal lobule volume and schneiderian first-rank symptoms in antipsychotic-naïve schizophrenia: a 3-tesla MRI study
    Vijay Danivas
    Department of Psychiatry, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, India
    Indian J Psychol Med 31:82-7. 2009
    ..The specific role of IPL structural abnormalities in the pathogenesis of FRS is yet to be ascertained...
  35. doi request reprint Psychogenic polydipsia in bipolar affective disorder--a case report
    Karthik Duraiswamy
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560029, India
    Gen Hosp Psychiatry 33:84.e9-10. 2011
    ..One needs to be cautious in choosing the mood stabilizer while treating this condition. We report the successful treatment of a patient with BPAD and polydipsia on a combination of valproate and risperidone...
  36. doi request reprint Antithetical asymmetry in schizophrenia and bipolar affective disorder: a line bisection study
    Naren P Rao
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Bipolar Disord 12:221-9. 2010
    ..For the first time, we report concurrent analyses of asymmetry in BPAD and schizophrenia using a line bisection task...
  37. ncbi request reprint Corpus callosum abnormalities associated with greater externalizing behaviors in subjects at high risk for alcohol dependence
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore 560029, India
    Psychiatry Res 156:209-15. 2007
    ..Smaller CC areas and their negative association with externalizing behaviors may represent yet another marker of susceptibility to alcoholism in high-risk subjects...
  38. ncbi request reprint Clinical correlates of nucleus accumbens volume in drug-naive, adult patients with obsessive-compulsive disorder
    Janardhanan C Narayanaswamy
    Obsessive Compulsive Disorder Clinic and Translational Psychiatry Lab, Neurobiology Research Center at National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, India
    Aust N Z J Psychiatry 47:930-7. 2013
    ..We report on the volumetric abnormalities of NAcc and its correlation with illness severity in drug-naïve, adult patients with OCD...
  39. pmc Neurohemodynamic correlates of 'OM' chanting: A pilot functional magnetic resonance imaging study
    Bangalore G Kalyani
    Department of Psychiatry, Advanced Center for Yoga, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Int J Yoga 4:3-6. 2011
    ..This has the potential for vagus nerve stimulation through its auricular branches and the effects on the brain thereof. The neurohemodynamic correlates of 'OM' chanting are yet to be explored...
  40. doi request reprint Successful treatment of co-morbid schizophrenia and multiple sclerosis
    Eesha Sharma
    Department of Psychiatry, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, India
    Asian J Psychiatr 3:235-6. 2010
    ..We, for the first time, report a patient with MS and paranoid schizophrenia successfully treated with concurrent use of clozapine and risperidone with interferon-beta-1a...
  41. doi request reprint Rapid improvement of auditory verbal hallucinations in schizophrenia after add-on treatment with transcranial direct-current stimulation
    Venkataram Shivakumar
    Schizophrenia Clinic, Department of Psychiatry and Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 29:e43-4. 2013
    ..Because transcranial direct-current stimulation is safe, largely well tolerated, and relatively inexpensive, this add-on treatment option is worth exploring through further rigorous studies. ..
  42. doi request reprint Clinical correlates of caudate volume in drug-naïve adult patients with obsessive-compulsive disorder
    Janardhanan C Narayanaswamy
    Department of Psychiatry, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, India
    Psychiatry Res 212:7-13. 2013
    ..However, it demonstrated a robust relationship between volume of the left caudate body and the severity of OCD. Additionally, there was a sexual dimorphism in caudate volume in OCD...
  43. pmc Obsessive compulsive disorder masquerading as psychosis
    Dhanya Raveendranathan
    Department of Psychiatry, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, Karnataka, India
    Indian J Psychol Med 34:179-80. 2012
    ..This can indeed pose a considerable challenge, especially in a scenario where the phenomenon is difficult to discern. We report a case of OCD, which was initially diagnosed as psychosis...
  44. ncbi request reprint Risperidone treatment for polydipsia and hyponatremia in schizophrenia: a case report
    Naren Rao
    National Institute of Mental Health and Neurosciences, Department of Psychiatry, Bangalore, India
    Turk Psikiyatri Derg 22:123-5. 2011
    ..Herein we present a schizophrenia case with polydipsia and hyponatremia that was successfully treated with risperidone...
  45. ncbi request reprint Longitudinal study of beta2-microglobulin abnormalities in schizophrenia
    Seetharamaiah Chittiprol
    Department of Neurochemistry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Int Immunopharmacol 9:1215-7. 2009
    ..Moreover, the observations suggest the possibility that the mechanism of action of antipsychotics might involve alteration of immune parameters...
  46. ncbi request reprint Electroconvulsive therapy in the treatment of delirious mania: a report of 2 patients
    Vijay Danivas
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 26:278-9. 2010
    ..Differential diagnosis of the above clinical presentation includes neuroleptic malignant syndrome and malignant catatonia. Delirious mania is clinically important owing to the potential for diagnostic confusion and good response to ECTs...
  47. doi request reprint Recent advances in psychoneuroimmunology relevant to schizophrenia therapeutics
    Monojit Debnath
    Department of Human Genetics, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Curr Opin Psychiatry 26:433-9. 2013
    ..Such psychoneuroimmunological aberrations essentially argue for an alternative treatment approach based on immunomodulation in schizophrenia...
  48. pmc Relationship between Interleukin-6 Gene Polymorphism and Hippocampal Volume in Antipsychotic-Naïve Schizophrenia: Evidence for Differential Susceptibility?
    Sunil Vasu Kalmady
    The Schizophrenia Clinic, Department of Psychiatry, National Institute of Mental Health and Neuro Sciences, Bangalore, India Translational Psychiatry Laboratory, Cognitive Neurobiology Division, Neurobiology Research Centre, National Institute of Mental Health and Neuro Sciences, Bangalore, India
    PLoS ONE 9:e96021. 2014
    ..In this first-time study, we evaluated the relationship between functional polymorphism rs1800795 of IL-6 and hippocampal gray matter volume in antipsychotic-naïve schizophrenia patients in comparison with healthy controls...
  49. ncbi request reprint Hyperprolactinemia with aripiprazole: understanding the paradox
    Gayatri Saraf
    1The Metabolic Clinic in Psychiatry, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India and 2Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, India
    Am J Ther 21:e80-1. 2014
    ..This partial D2 agonistic activity of aripiprazole could be dose related, and hence, at higher doses, aripiprazole by itself can have dopamine antagonistic properties and hence cause prolactin system abnormalities. ..
  50. pmc Family history correlates of digit ratio abnormalities in schizophrenia
    Anjith Divakaran
    Department of Psychiatry and Translational Psychiatry Laboratory, Neurobiology Research Center, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychol Med 34:355-9. 2012
    ..In this study, we sought to examine the sex differences and the influence of family history of psychosis on digit ratio in patients with schizophrenia compared to matched healthy controls (HCs)...
  51. doi request reprint Hyperthyroidism presenting as mixed affective state: a case report
    Mukund G Rao
    Department of Psychiatry, National Institute of Mental Health and Neuro Sciences, Bangalore 560029, India
    Gen Hosp Psychiatry 34:703.e13-4. 2012
    ..We present a case of hyperthyroidism presenting as a mixed affective state and the successful resolution of psychiatric symptoms with antithyroid medication along with a mood-stabilizing agent...
  52. ncbi request reprint Abnormalities in cortical and transcallosal inhibitory mechanisms in subjects at high risk for alcohol dependence: a TMS study
    Kesavan Muralidharan
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Addict Biol 13:373-9. 2008
    ....
  53. pmc Volume and asymmetry abnormalities of insula in antipsychotic-naive schizophrenia: a 3-tesla magnetic resonance imaging study
    Harve Shanmugam Virupaksha
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychol Med 34:133-9. 2012
    ..Existing studies on insula volume abnormalities report inconsistent findings potentially due to the evaluation of 'antipsychotic-treated' schizophrenia patients as well as suboptimal methodology...
  54. ncbi request reprint Beneficial effects of add-on raloxifene in schizophrenia
    Dhanya Raveendranathan
    The Metabolic Clinic in Psychiatry, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Arch Womens Ment Health 15:147-148. 2012
    ..The patient, a 29-year-old woman, over a 7-month followup period, showed significant improvement in sociooccupational functioning, with reduction in symptom severity...
  55. ncbi request reprint Has Kahlbaum syndrome disappeared or is it underdiagnosed? Reexamining the nosology of catatonia
    Naren P Rao
    J ECT 28:62-3. 2012
    ..Further prospective studies examining the natural course are needed, which could have significant implications on future classificatory systems...
  56. pmc Acyclovir in bipolar disorder: a mismatched combination?
    Naveen Jayaram
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychol Med 33:208-9. 2011
    ..Our report suggests that acyclovir is a risk factor for mood episode in vulnerable individual and one need to be cautious while using antiviral agents in patients with psychiatric disorders...
  57. ncbi request reprint Olanzapine-induced clinical seizure: a case report
    Rishikesh V Behere
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Clin Neuropharmacol 32:297-8. 2009
    ..Olanzapine has a profile similar to that of clozapine and shares its seizure-inducing potential. Typical antipsychotics such as haloperidol might be a safer option for such patients...
  58. ncbi request reprint Neuropsychological performance in OCD: a study in medication-naïve patients
    Rakhee Krishna
    National Institute of Mental Health and Neuro Sciences NIMHANS, Bangalore, India
    Prog Neuropsychopharmacol Biol Psychiatry 35:1969-76. 2011
    ..One potential reason for poor replication is the confounding influence of medications. There is limited research on neuropsychological performance in medication-naïve, never treated OCD patients...
  59. doi request reprint Evolutionary genetic analyses of MEF2C gene: implications for learning and memory in Homo sapiens
    Sunil V Kalmady
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Asian J Psychiatr 6:56-9. 2013
    ..Further research on this gene might unravel the potential role of this gene in learning and memory as well as its pathogenetic effect in certain hippocampal disorders with evolutionary basis like schizophrenia...
  60. pmc Successful use of add - on topiramate for antipsychotic - induced weight gain
    Venkataram Shivakumar
    Department of Psychiatry, The Metabolic Clinic in Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychol Med 34:85-6. 2012
    ..In this case report, we describe the use of low - dose topiramate as a weight - reducing agent, in a patient with a bipolar affective disorder - mania with psychotic symptoms, who had significant risperidone - induced weight gain...
  61. pmc Orbitofrontal Lobe Volume Deficits in Antipsychotic-Naïve Schizophrenia: A 3-Tesla MRI study
    Rishikesh V Behere
    Department of Psychiatry, The Schizophrenia Clinic, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, India
    Indian J Psychol Med 31:77-81. 2009
    ..While these functional impairments are established in schizophrenia, the OFL volume deficits have not been well studied, especially in antipsychotic-naïve patients...
  62. ncbi request reprint Optimized voxel-based morphometry of gray matter volume in first-episode, antipsychotic-naive schizophrenia
    Peruvamba N Jayakumar
    Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore 560029, India
    Prog Neuropsychopharmacol Biol Psychiatry 29:587-91. 2005
    ..Findings suggest limbic, heteromodal cortical, striatal, thalamic and cerebellar abnormalities in schizophrenia...
  63. doi request reprint Emotional interference in obsessive-compulsive disorder: a neuropsychological study using optimized emotional Stroop test
    Naren Prahlada Rao
    Department of Psychiatry, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, India
    Psychiatry Res 180:99-104. 2010
    ..Study findings suggest the presence of selective emotional bias for OCD relevant stimuli in these patients and this bias is potentially related to symptomatic status. These observations are in tune with the threat-relatedness hypothesis...
  64. pmc Clinical correlates of thalamus volume deficits in anti-psychotic-naïve schizophrenia patients: A 3-Tesla MRI study
    Naren P Rao
    Department of Psychiatry, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore 560 029, India
    Indian J Psychiatry 52:229-35. 2010
    ..The thalamus volume in anti-psychotic-naïve patients determined using high-resolution 3-Tesla magnetic resonance imaging (MRI) has not yet been examined...
  65. ncbi request reprint Gray matter volume abnormalities and externalizing symptoms in subjects at high risk for alcohol dependence
    Vivek Benegal
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Addict Biol 12:122-32. 2007
    ..Subjects at HR for alcoholism have reduced volumes of critical areas of brain gray matter, which are associated with increased externalizing symptoms. These represent key endophenotypes of alcoholism...
  66. ncbi request reprint Successful use of donepezil in treatment of cognitive impairment caused by maintenance electroconvulsive therapy: a case report
    Naren P Rao
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    J ECT 25:216-8. 2009
    ..The role of cholinesterase inhibitors in the treatment of cognitive deficits caused by ECT needs further studies...
  67. doi request reprint The TRIPS (Toll-like receptors in immuno-inflammatory pathogenesis) Hypothesis: a novel postulate to understand schizophrenia
    Ganesan Venkatasubramanian
    The Schizophrenia Clinic, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore 560029, India
    Prog Neuropsychopharmacol Biol Psychiatry 44:301-11. 2013
    ....
  68. doi request reprint Clinically significant hoarding in obsessive-compulsive disorder: results from an Indian study
    Vaskar Chakraborty
    National Institute of Mental Health and Neuro Sciences, Bangalore, India
    Compr Psychiatry 53:1153-60. 2012
    ..Most of the research on hoarding is from the Western countries. This study aimed to provide data on the prevalence and correlates of clinically significant hoarding in a large sample of patients with OCD from the Indian subcontinent...
  69. doi request reprint Neuroimaging studies in schizophrenia: an overview of research from Asia
    Janardhanan C Narayanaswamy
    Schizophrenia Clinic, Department of Psychiatry, Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bangalore, India
    Int Rev Psychiatry 24:405-16. 2012
    ..In addition, theoretically relevant relationships between these brain abnormalities and developmental aberrations suggest possible neurodevelopmental basis for these brain deficits...
  70. ncbi request reprint White matter abnormalities in children and adolescents with obsessive-compulsive disorder: a diffusion tensor imaging study
    Rajan Nishanth Jayarajan
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Depress Anxiety 29:780-8. 2012
    ..There is paucity of data on white matter (WM) abnormalities in juvenile obsessive-compulsive disorder (OCD). This study aimed to identify WM microstructure changes in juvenile OCD...
  71. pmc Neurological soft signs in schizophrenia - The past, the present and the future
    Shivarama Varambally
    Department of Psychiatry, Schizophrenia Clinic, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychiatry 54:73-80. 2012
    ..NSS, by themselves or as a composite index with other neurobiological parameters, hold potential as a candidate endophenotype for schizophrenia...
  72. pmc Proton magnetic resonance spectroscopy in depression
    Naren P Rao
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India
    Indian J Psychiatry 53:307-11. 2011
    ..Spectroscopy also has potential implications in predicting the response to treatment and formulating individualized pharmacotherapy...
  73. pmc Do antipsychotics limit disability in schizophrenia? A naturalistic comparative study in the community
    Jagadisha Thirthalli
    Department of Psychiatry, National Institute of Mental Health and Neurosciences NIMHANS, Bangalore, India
    Indian J Psychiatry 52:37-41. 2010
    ..Though antipsychotics are effective against symptoms of schizophrenia and prevent relapses, their effect on disability has not been studied in a comparative design...
  74. doi request reprint Gray matter volume deficits in spinocerebellar ataxia: an optimized voxel based morphometric study
    Gaurav Goel
    Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore, Karnataka, India
    Parkinsonism Relat Disord 17:521-7. 2011
    ..Voxel-based morphometry (VBM) provides an automated unbiased analysis of structural MRI scans and gives a comprehensive assessment of anatomical differences throughout the brain...
  75. pmc A functional Magnetic Resonance Imaging study of neurohemodynamic abnormalities during emotion processing in subjects at high risk for schizophrenia
    Ganesan Venkatasubramanian
    Department of Psychiatry, National Institute of Mental Health and Neuro Sciences NIMHANS, Bangalore, Karnataka, India
    Indian J Psychiatry 52:308-15. 2010
    ..The brain functional correlates of emotion processing in these HR subjects in the context of ecologically valid, real-life dynamic images using functional Magnetic Resonance Imaging (fMRI) has not been examined previously...