Carmen E Contreras
Affiliation: Universidad Central de Venezuela
- Genetics of drug-resistant Plasmodium falciparum malaria in the Venezuelan state of BolivarCarmen E Contreras
Immunology Institute, School of Medicine, Central University, Caracas, Venezuela
Am J Trop Med Hyg 67:400-5. 2002..falciparum malaria in Bolivar, and an invasion of multi-resistant pathogens from Brazil. Despite national restrictions on the use of SP and chloroquine, genotypic resistance to these therapies remains widespread in Bolivar...
- Stage-specific activity of potential antimalarial compounds measured in vitro by flow cytometry in comparison to optical microscopy and hypoxanthine uptakeCarmen E Contreras
Instituto de Inmunologia, Facultad de Medicina, Universidad Central, Apartado Postal 50109, Caracas 1050 A, Venezuela
Mem Inst Oswaldo Cruz 99:179-84. 2004..Advantages of flow cytometry analysis over traditional assays included higher throughput for data collection, insight into the stage-specificity of antimalarial activity avoiding use of radioactive isotopes...
- Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South AmericaJoseph F Cortese
Malaria Section, Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
J Infect Dis 186:999-1006. 2002..This study highlights the importance of continent-wide malaria-control policies and suggests that the containment of resistance to the next generation of therapies may be feasible...